{"id":"https://openalex.org/W2085184280","doi":"https://doi.org/10.1109/nems.2013.6559946","title":"Dynamic separation of b-lymphoma cells from red blood cells using optically-induced electrokinetics","display_name":"Dynamic separation of b-lymphoma cells from red blood cells using optically-induced electrokinetics","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2085184280","doi":"https://doi.org/10.1109/nems.2013.6559946","mag":"2085184280"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2013.6559946","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2013.6559946","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009435651","display_name":"Wenfeng Liang","orcid":"https://orcid.org/0000-0002-6605-2511"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenfeng Liang","raw_affiliation_strings":["Chinese Academy of Sciences, Beijing, China","State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100395613","display_name":"Bin Liu","orcid":"https://orcid.org/0009-0007-0797-0658"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Liu","raw_affiliation_strings":["State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040326170","display_name":"Lianqing Liu","orcid":"https://orcid.org/0000-0002-2271-5870"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianqing Liu","raw_affiliation_strings":["State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109102616","display_name":"Zaili Dong","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zaili Dong","raw_affiliation_strings":["State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007513075","display_name":"Gwo\u2010Bin Lee","orcid":"https://orcid.org/0000-0001-6910-9133"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Gwo-Bin Lee","raw_affiliation_strings":["Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036337382","display_name":"Wen J. Li","orcid":"https://orcid.org/0000-0001-9616-6213"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]},{"id":"https://openalex.org/I142078773","display_name":"Shenyang Institute of Automation","ror":"https://ror.org/00ft6nj33","country_code":"CN","type":"facility","lineage":["https://openalex.org/I142078773","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"funder","lineage":["https://openalex.org/I19820366"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Wen J. Li","raw_affiliation_strings":["Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China","State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong, China","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China","institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069604153","display_name":"Weijing Zhang","orcid":"https://orcid.org/0000-0003-0730-7606"},"institutions":[{"id":"https://openalex.org/I2802541053","display_name":"Academy of Military Medical Sciences","ror":"https://ror.org/02bv3c993","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijing Zhang","raw_affiliation_strings":["Department of Lymphoma, Affiliated Hospital of Military Medical Academy of Sciences, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Department of Lymphoma, Affiliated Hospital of Military Medical Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I2802541053"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5009435651"],"corresponding_institution_ids":["https://openalex.org/I142078773","https://openalex.org/I19820366"],"apc_list":null,"apc_paid":null,"fwci":0.2124,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.58469669,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1253","last_page":"1256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dielectrophoresis","display_name":"Dielectrophoresis","score":0.7911025285720825},{"id":"https://openalex.org/keywords/electrokinetic-phenomena","display_name":"Electrokinetic phenomena","score":0.6699380278587341},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6094411015510559},{"id":"https://openalex.org/keywords/raji-cell","display_name":"Raji cell","score":0.5700527429580688},{"id":"https://openalex.org/keywords/electrophoresis","display_name":"Electrophoresis","score":0.49366816878318787},{"id":"https://openalex.org/keywords/polarization","display_name":"Polarization (electrochemistry)","score":0.4103270173072815},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.3875255286693573},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.32649263739585876},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3237978219985962},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.24020549654960632},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.22348180413246155},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.11794567108154297}],"concepts":[{"id":"https://openalex.org/C106825181","wikidata":"https://www.wikidata.org/wiki/Q902890","display_name":"Dielectrophoresis","level":3,"score":0.7911025285720825},{"id":"https://openalex.org/C27703432","wikidata":"https://www.wikidata.org/wiki/Q2778467","display_name":"Electrokinetic phenomena","level":2,"score":0.6699380278587341},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6094411015510559},{"id":"https://openalex.org/C16232356","wikidata":"https://www.wikidata.org/wiki/Q4215980","display_name":"Raji cell","level":3,"score":0.5700527429580688},{"id":"https://openalex.org/C40250595","wikidata":"https://www.wikidata.org/wiki/Q185098","display_name":"Electrophoresis","level":2,"score":0.49366816878318787},{"id":"https://openalex.org/C205049153","wikidata":"https://www.wikidata.org/wiki/Q2698605","display_name":"Polarization (electrochemistry)","level":2,"score":0.4103270173072815},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3875255286693573},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.32649263739585876},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3237978219985962},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24020549654960632},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.22348180413246155},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.11794567108154297},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nems.2013.6559946","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2013.6559946","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320326784","display_name":"CAS-Croucher Funding Scheme for Joint Laboratories","ror":null},{"id":"https://openalex.org/F4320334994","display_name":"CAS-SAFEA International Partnership Program for Creative Research Teams","ror":"https://ror.org/055gka453"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W208653037","https://openalex.org/W1991115160","https://openalex.org/W2018421561","https://openalex.org/W2021621458","https://openalex.org/W2036345425","https://openalex.org/W2049599658","https://openalex.org/W2069939467","https://openalex.org/W2087096498","https://openalex.org/W2132731060","https://openalex.org/W2133862726","https://openalex.org/W2136129902","https://openalex.org/W2223822801"],"related_works":["https://openalex.org/W2133073029","https://openalex.org/W2133195325","https://openalex.org/W1553078627","https://openalex.org/W2137256762","https://openalex.org/W2592418396","https://openalex.org/W1675708030","https://openalex.org/W170918341","https://openalex.org/W2949555527","https://openalex.org/W3105048124","https://openalex.org/W592448233"],"abstract_inverted_index":{"This":[0],"study":[1],"reports":[2],"an":[3,22],"approach":[4],"to":[5],"dynamically":[6],"separate":[7],"cultured":[8],"human":[9,15],"B-lymphoma":[10],"(Raji)":[11],"cells":[12,18,47,84,101,172],"from":[13,173],"normal":[14],"red":[16],"blood":[17],"(RBCs),":[19],"mixed":[20],"in":[21],"isotonic":[23],"solution,":[24],"by":[25,88,105],"utilizing":[26],"a":[27,60,71,141,148],"hydrogenated":[28],"amorphous":[29],"silicon-based":[30],"optically-induced":[31,64,176],"electrokinetics":[32],"chip.":[33],"A":[34],"theoretical":[35,76],"calculation":[36],"of":[37,46,62,83,100,111,144,151,157,167,170],"the":[38,42,55,63,80,90,97,120,125,130,155,163],"polarization":[39],"model":[40],"for":[41,128],"two":[43,81,98,107],"different":[44,112],"types":[45,82,99],"is":[48,68,134,162],"first":[49,164],"presented.":[50],"The":[51,75],"differential":[52],"velocity":[53],"between":[54],"cell":[56],"types,":[57],"generated":[58],"as":[59,124],"result":[61],"dielectrophoresis":[65],"(ODEP)":[66],"force":[67],"obtained":[69],"using":[70,89,106,140,175],"finite":[72],"element":[73],"method.":[74],"results":[77,94],"indicate":[78],"that":[79,96],"could":[85],"be":[86,103],"separated":[87,104],"ODEP":[91,131],"force.":[92,132],"Experimental":[93],"verified":[95],"can":[102],"optically":[108],"projected":[109,116],"lines":[110],"widths,":[113],"with":[114,136],"one":[115],"line":[117,122],"moving":[118],"and":[119],"other":[121],"stationary,":[123],"virtual":[126,138],"electrodes":[127,139],"generating":[129],"Separation":[133],"achieved":[135],"these":[137],"bias":[142],"potential":[143],"20":[145],"Vpp":[146],"at":[147],"driving":[149],"frequency":[150],"50":[152],"kHz.":[153],"To":[154],"best":[156],"our":[158],"knowledge,":[159],"this":[160],"work":[161],"experimental":[165],"validation":[166],"rapid":[168],"separation":[169],"Raji":[171],"RBCs":[174],"electrokinetics.":[177]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}