{"id":"https://openalex.org/W2005351309","doi":"https://doi.org/10.1109/nems.2012.6196832","title":"Microfluidic circulatory system for the raise of liver urea assay","display_name":"Microfluidic circulatory system for the raise of liver urea assay","publication_year":2012,"publication_date":"2012-03-01","ids":{"openalex":"https://openalex.org/W2005351309","doi":"https://doi.org/10.1109/nems.2012.6196832","mag":"2005351309"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2012.6196832","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2012.6196832","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047502740","display_name":"Yu-Shih Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yu-Shih Chen","raw_affiliation_strings":["Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu, Taiwan","[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]"],"affiliations":[{"raw_affiliation_string":"Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023590611","display_name":"Tzu-Hsuan Dai","orcid":null},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tzu-Hsuan Dai","raw_affiliation_strings":["Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","Department of Power Mechanical Engineering, National Tsing Hua University, HsinChu, TAIWAN"],"affiliations":[{"raw_affiliation_string":"Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"Department of Power Mechanical Engineering, National Tsing Hua University, HsinChu, TAIWAN","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040405562","display_name":"Ling-Yi Ke","orcid":null},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ling-Yi Ke","raw_affiliation_strings":["Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu, Taiwan","[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]"],"affiliations":[{"raw_affiliation_string":"Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]","institution_ids":["https://openalex.org/I25846049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081252439","display_name":"Cheng\u2010Hsien Liu","orcid":"https://orcid.org/0000-0003-1882-3892"},"institutions":[{"id":"https://openalex.org/I25846049","display_name":"National Tsing Hua University","ror":"https://ror.org/00zdnkx70","country_code":"TW","type":"education","lineage":["https://openalex.org/I25846049"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Cheng-Hsien Liu","raw_affiliation_strings":["Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]"],"affiliations":[{"raw_affiliation_string":"Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I25846049"]},{"raw_affiliation_string":"[Institute of NanoEngineering and MicroSystems, National Tsing-Hua University, Hsinchu, Taiwan]","institution_ids":["https://openalex.org/I25846049"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5047502740"],"corresponding_institution_ids":["https://openalex.org/I25846049"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08205086,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"295","issue":null,"first_page":"533","last_page":"536"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9684000015258789,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lobules-of-liver","display_name":"Lobules of liver","score":0.6591694951057434},{"id":"https://openalex.org/keywords/circulatory-system","display_name":"Circulatory system","score":0.6451917290687561},{"id":"https://openalex.org/keywords/blood-vessel","display_name":"Blood vessel","score":0.624157726764679},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.48314279317855835},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.4806289076805115},{"id":"https://openalex.org/keywords/blood-flow","display_name":"Blood flow","score":0.4726908504962921},{"id":"https://openalex.org/keywords/portal-vein","display_name":"Portal vein","score":0.452372670173645},{"id":"https://openalex.org/keywords/organ-on-a-chip","display_name":"Organ-on-a-chip","score":0.43043234944343567},{"id":"https://openalex.org/keywords/microchannel","display_name":"Microchannel","score":0.41384032368659973},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.38265812397003174},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2799869179725647},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.2735065817832947},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2306976318359375},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.21039137244224548},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.14678794145584106},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.12036758661270142}],"concepts":[{"id":"https://openalex.org/C57322979","wikidata":"https://www.wikidata.org/wiki/Q11611496","display_name":"Lobules of liver","level":2,"score":0.6591694951057434},{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.6451917290687561},{"id":"https://openalex.org/C2777663904","wikidata":"https://www.wikidata.org/wiki/Q988343","display_name":"Blood vessel","level":2,"score":0.624157726764679},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.48314279317855835},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.4806289076805115},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4726908504962921},{"id":"https://openalex.org/C2779033008","wikidata":"https://www.wikidata.org/wiki/Q464543","display_name":"Portal vein","level":2,"score":0.452372670173645},{"id":"https://openalex.org/C165932988","wikidata":"https://www.wikidata.org/wiki/Q7101746","display_name":"Organ-on-a-chip","level":3,"score":0.43043234944343567},{"id":"https://openalex.org/C63662833","wikidata":"https://www.wikidata.org/wiki/Q6839341","display_name":"Microchannel","level":2,"score":0.41384032368659973},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.38265812397003174},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2799869179725647},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2735065817832947},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2306976318359375},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21039137244224548},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.14678794145584106},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12036758661270142}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nems.2012.6196832","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2012.6196832","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2030450624","https://openalex.org/W2041558541","https://openalex.org/W2082932879","https://openalex.org/W2093082279","https://openalex.org/W2113042424","https://openalex.org/W2119708685","https://openalex.org/W4211147424","https://openalex.org/W4229950336","https://openalex.org/W4250993795"],"related_works":["https://openalex.org/W1818839458","https://openalex.org/W2387714547","https://openalex.org/W3095560982","https://openalex.org/W2188344331","https://openalex.org/W2074393817","https://openalex.org/W3153910332","https://openalex.org/W2153310131","https://openalex.org/W2005351309","https://openalex.org/W2153579604","https://openalex.org/W2583102966"],"abstract_inverted_index":{"In":[0],"this":[1,73],"research,":[2],"we":[3],"propose":[4],"an":[5],"in":[6,24,42,56,64,72],"vitro":[7],"liver":[8,47,61,91,105],"circulatory":[9,95],"system":[10,63,69,77,96],"via":[11,108],"the":[12,51,60],"concept":[13],"of":[14,28,38,79,82,100],"cell":[15],"pattern":[16,110],"technology":[17],"and":[18,32,90,104,112],"microfluidic":[19,113],"system.":[20],"Liver":[21,94],"lobule":[22,48],"structure":[23],"our":[25],"body":[26],"consisted":[27,78,99],"several":[29],"blood":[30,39,85,101],"vessel":[31,86,102],"hepatic":[33,44,52],"tissue.":[34],"The":[35],"fluid":[36],"direction":[37],"would":[40],"get":[41],"from":[43],"portal":[45],"vein,":[46],"tissue":[49,92,106],"to":[50,58],"central":[53],"vein.":[54],"Hence,":[55],"order":[57],"mimic":[59],"circular":[62],"vitro,":[65],"a":[66],"connected":[67,76],"microchannel":[68],"is":[70,98],"proposed":[71],"research.":[74],"This":[75],"three":[80],"parts":[81],"channel":[83,89,114],"design,":[84],"chamber,":[87],"Lobule-flow-mimic":[88],"chamber.":[93],"chip":[97],"chamber":[103,107],"dielectrophoresis":[109],"method":[111],"design.":[115]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}