{"id":"https://openalex.org/W2111828760","doi":"https://doi.org/10.1109/nems.2012.6196759","title":"Three-dimensional lab-on-a-CD with enzyme-linked immunosorbent assay","display_name":"Three-dimensional lab-on-a-CD with enzyme-linked immunosorbent assay","publication_year":2012,"publication_date":"2012-03-01","ids":{"openalex":"https://openalex.org/W2111828760","doi":"https://doi.org/10.1109/nems.2012.6196759","mag":"2111828760"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2012.6196759","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2012.6196759","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090318427","display_name":"Masaki Ishizawa","orcid":null},"institutions":[{"id":"https://openalex.org/I180941496","display_name":"University of Hyogo","ror":"https://ror.org/0151bmh98","country_code":"JP","type":"education","lineage":["https://openalex.org/I180941496"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"M. Ishizawa","raw_affiliation_strings":["Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan","institution_ids":["https://openalex.org/I180941496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027999988","display_name":"Tsukasa Azeta","orcid":null},"institutions":[{"id":"https://openalex.org/I180941496","display_name":"University of Hyogo","ror":"https://ror.org/0151bmh98","country_code":"JP","type":"education","lineage":["https://openalex.org/I180941496"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Azeta","raw_affiliation_strings":["Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan","institution_ids":["https://openalex.org/I180941496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074820882","display_name":"Hiroaki Nose","orcid":null},"institutions":[{"id":"https://openalex.org/I180941496","display_name":"University of Hyogo","ror":"https://ror.org/0151bmh98","country_code":"JP","type":"education","lineage":["https://openalex.org/I180941496"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Nose","raw_affiliation_strings":["Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan","institution_ids":["https://openalex.org/I180941496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021902512","display_name":"Yoshiaki Ukita","orcid":"https://orcid.org/0000-0002-3267-6940"},"institutions":[{"id":"https://openalex.org/I177738480","display_name":"Japan Advanced Institute of Science and Technology","ror":"https://ror.org/03frj4r98","country_code":"JP","type":"education","lineage":["https://openalex.org/I177738480"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Ukita","raw_affiliation_strings":["Japan Advanced Institute of Science and Technology, Japan","Japan Advanced Institute of Science and Technology, Japan#TAB#"],"affiliations":[{"raw_affiliation_string":"Japan Advanced Institute of Science and Technology, Japan","institution_ids":["https://openalex.org/I177738480"]},{"raw_affiliation_string":"Japan Advanced Institute of Science and Technology, Japan#TAB#","institution_ids":["https://openalex.org/I177738480"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056946407","display_name":"Y. Utsumi","orcid":"https://orcid.org/0000-0002-2221-278X"},"institutions":[{"id":"https://openalex.org/I180941496","display_name":"University of Hyogo","ror":"https://ror.org/0151bmh98","country_code":"JP","type":"education","lineage":["https://openalex.org/I180941496"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Utsumi","raw_affiliation_strings":["Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Laboratory of Advanced Science and Technology for Industry, University of Hyogo, Japan","institution_ids":["https://openalex.org/I180941496"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5090318427"],"corresponding_institution_ids":["https://openalex.org/I180941496"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.14960525,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"257","issue":null,"first_page":"213","last_page":"217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microchannel","display_name":"Microchannel","score":0.8646825551986694},{"id":"https://openalex.org/keywords/capillary-action","display_name":"Capillary action","score":0.6970301866531372},{"id":"https://openalex.org/keywords/bundle","display_name":"Bundle","score":0.6564182639122009},{"id":"https://openalex.org/keywords/lithography","display_name":"Lithography","score":0.5988763570785522},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.547310471534729},{"id":"https://openalex.org/keywords/synchrotron","display_name":"Synchrotron","score":0.5134907364845276},{"id":"https://openalex.org/keywords/synchrotron-radiation","display_name":"Synchrotron radiation","score":0.5115047693252563},{"id":"https://openalex.org/keywords/photolithography","display_name":"Photolithography","score":0.45834797620773315},{"id":"https://openalex.org/keywords/detection-limit","display_name":"Detection limit","score":0.42573463916778564},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.40655410289764404},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.36027252674102783},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.28369033336639404},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.27806341648101807},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.20005083084106445},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.1662158966064453},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1291247010231018}],"concepts":[{"id":"https://openalex.org/C63662833","wikidata":"https://www.wikidata.org/wiki/Q6839341","display_name":"Microchannel","level":2,"score":0.8646825551986694},{"id":"https://openalex.org/C196806460","wikidata":"https://www.wikidata.org/wiki/Q188603","display_name":"Capillary action","level":2,"score":0.6970301866531372},{"id":"https://openalex.org/C2778134712","wikidata":"https://www.wikidata.org/wiki/Q1047307","display_name":"Bundle","level":2,"score":0.6564182639122009},{"id":"https://openalex.org/C204223013","wikidata":"https://www.wikidata.org/wiki/Q133036","display_name":"Lithography","level":2,"score":0.5988763570785522},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.547310471534729},{"id":"https://openalex.org/C21368211","wikidata":"https://www.wikidata.org/wiki/Q689863","display_name":"Synchrotron","level":2,"score":0.5134907364845276},{"id":"https://openalex.org/C16332341","wikidata":"https://www.wikidata.org/wiki/Q212871","display_name":"Synchrotron radiation","level":2,"score":0.5115047693252563},{"id":"https://openalex.org/C105487726","wikidata":"https://www.wikidata.org/wiki/Q622938","display_name":"Photolithography","level":2,"score":0.45834797620773315},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.42573463916778564},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.40655410289764404},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.36027252674102783},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.28369033336639404},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.27806341648101807},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.20005083084106445},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.1662158966064453},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1291247010231018}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nems.2012.6196759","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2012.6196759","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1649220013","https://openalex.org/W1994277623","https://openalex.org/W1999402111","https://openalex.org/W2005780072","https://openalex.org/W2016824683","https://openalex.org/W2022998334","https://openalex.org/W2026908430","https://openalex.org/W2031223405","https://openalex.org/W2052549353","https://openalex.org/W2077018068","https://openalex.org/W2121757279","https://openalex.org/W2182524538","https://openalex.org/W6686046796"],"related_works":["https://openalex.org/W2088257409","https://openalex.org/W2091796379","https://openalex.org/W3102196204","https://openalex.org/W2095169963","https://openalex.org/W1670732023","https://openalex.org/W1993104109","https://openalex.org/W2002555761","https://openalex.org/W1996523313","https://openalex.org/W2330651818","https://openalex.org/W1631512605"],"abstract_inverted_index":{"This":[0],"paper":[1],"reports":[2],"a":[3],"new":[4],"type":[5],"of":[6,21,39,68,94],"lab-on-a-CD":[7,24],"device":[8,19],"with":[9,26,48],"three-dimensional":[10,104],"microchannel":[11],"networks":[12],"and":[13,30,42,62,87,106],"vertical":[14,31,49,77],"capillary":[15,78],"bundle":[16,79],"structure.":[17],"The":[18,45],"consist":[20],"the":[22,36,64,103,111],"multiple":[23],"chips":[25,65],"conventional":[27],"planer":[28],"microchannels":[29,32],"which":[33],"constructed":[34],"on":[35],"disks":[37],"made":[38],"poly-dimethylsiloxane":[40],"(PDMS)":[41],"poly-methylmethacrilrate":[43],"(PMMA).":[44],"PMMA":[46],"layer":[47],"channel":[50],"were":[51],"fabricated":[52,63],"by":[53,83,123],"deep":[54],"X-ray":[55],"lithography":[56],"using":[57],"synchrotron":[58],"radiation.":[59],"We":[60],"designed":[61],"for":[66],"aim":[67],"taking":[69],"enzyme-linked":[70],"immunosorbent":[71],"assay(ELISA).":[72],"Three-dimensional":[73],"liquid":[74],"transportation":[75],"through":[76],"structure":[80],"is":[81,89,99,108],"suggested":[82],"computational":[84],"fluid":[85],"dynamics":[86],"it":[88,107],"successfully":[90,100],"demonstrated":[91,101],"chips.":[92],"Detection":[93],"immunogroblin":[95],"G(IgG)":[96],"from":[97],"mouse":[98],"in":[102],"devices":[105],"notable":[109],"that":[110],"result":[112],"suggests":[113],"quite":[114],"high-sensitive":[115],"implying":[116],"detection":[117],"limit":[118],"down":[119],"to":[120],"few":[121],"ng/mL":[122],"primitive":[124],"result.":[125]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}