{"id":"https://openalex.org/W2138090784","doi":"https://doi.org/10.1109/nems.2011.6017515","title":"Formation of droplets interface bilayer by coplanar EWOD device","display_name":"Formation of droplets interface bilayer by coplanar EWOD device","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2138090784","doi":"https://doi.org/10.1109/nems.2011.6017515","mag":"2138090784"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2011.6017515","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2011.6017515","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112980887","display_name":"Yi\u2010Ying Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yi-Ying Lin","raw_affiliation_strings":["Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069063940","display_name":"Ching\u2010Wen Chen","orcid":"https://orcid.org/0000-0003-1652-1495"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ching-Wen Chen","raw_affiliation_strings":["Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104110814","display_name":"Li-Chi Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Li-Chi Chen","raw_affiliation_strings":["Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023670598","display_name":"Shih\u2010Kang Fan","orcid":"https://orcid.org/0000-0002-1740-2992"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shih-Kang Fan","raw_affiliation_strings":["Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC"],"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu, 300 Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5112980887"],"corresponding_institution_ids":["https://openalex.org/I148366613"],"apc_list":null,"apc_paid":null,"fwci":0.265,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.63717503,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"12","issue":null,"first_page":"964","last_page":"967"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bilayer","display_name":"Bilayer","score":0.6231685876846313},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5870088934898376},{"id":"https://openalex.org/keywords/lipid-bilayer","display_name":"Lipid bilayer","score":0.5778931975364685},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.5538559556007385},{"id":"https://openalex.org/keywords/monolayer","display_name":"Monolayer","score":0.5422864556312561},{"id":"https://openalex.org/keywords/analytical-chemistry","display_name":"Analytical Chemistry (journal)","score":0.4909701645374298},{"id":"https://openalex.org/keywords/ion-channel","display_name":"Ion channel","score":0.47431468963623047},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.4443019926548004},{"id":"https://openalex.org/keywords/aperture","display_name":"Aperture (computer memory)","score":0.4423257112503052},{"id":"https://openalex.org/keywords/capacitance","display_name":"Capacitance","score":0.4347125291824341},{"id":"https://openalex.org/keywords/conductance","display_name":"Conductance","score":0.41753843426704407},{"id":"https://openalex.org/keywords/chemical-engineering","display_name":"Chemical engineering","score":0.38839012384414673},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.32266125082969666},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.26829034090042114},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.1567414104938507}],"concepts":[{"id":"https://openalex.org/C192157962","wikidata":"https://www.wikidata.org/wiki/Q4087243","display_name":"Bilayer","level":3,"score":0.6231685876846313},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5870088934898376},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.5778931975364685},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.5538559556007385},{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.5422864556312561},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.4909701645374298},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.47431468963623047},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4443019926548004},{"id":"https://openalex.org/C78336883","wikidata":"https://www.wikidata.org/wiki/Q4779385","display_name":"Aperture (computer memory)","level":2,"score":0.4423257112503052},{"id":"https://openalex.org/C30066665","wikidata":"https://www.wikidata.org/wiki/Q164399","display_name":"Capacitance","level":3,"score":0.4347125291824341},{"id":"https://openalex.org/C121932024","wikidata":"https://www.wikidata.org/wiki/Q5159376","display_name":"Conductance","level":2,"score":0.41753843426704407},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.38839012384414673},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32266125082969666},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26829034090042114},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.1567414104938507},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nems.2011.6017515","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2011.6017515","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5400000214576721,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1593321126","https://openalex.org/W1968386305","https://openalex.org/W1988901585","https://openalex.org/W1990107552","https://openalex.org/W2009025716","https://openalex.org/W2029678840","https://openalex.org/W2030683115","https://openalex.org/W2038770257","https://openalex.org/W2060996417","https://openalex.org/W2068561631","https://openalex.org/W2074370114","https://openalex.org/W2075124964","https://openalex.org/W2085381747","https://openalex.org/W2093513832","https://openalex.org/W2093638357","https://openalex.org/W2104034653","https://openalex.org/W2106847663","https://openalex.org/W2108952399","https://openalex.org/W2131445842","https://openalex.org/W2150068960","https://openalex.org/W2159159884"],"related_works":["https://openalex.org/W2389992822","https://openalex.org/W2061481432","https://openalex.org/W2100090167","https://openalex.org/W2010688654","https://openalex.org/W2718515487","https://openalex.org/W4367601614","https://openalex.org/W2072230736","https://openalex.org/W1963901611","https://openalex.org/W2059795428","https://openalex.org/W4206087209"],"abstract_inverted_index":{"Droplet":[0],"interface":[1,92],"bilayer":[2,24],"(DIB)":[3],"is":[4,43,88,137],"formed":[5],"on":[6],"a":[7,85,149,272],"microfabricated":[8],"aperture":[9,68,114,248],"between":[10,249],"two":[11,107,118,250],"addressable":[12],"encapsulated":[13,59,104,119,251,264],"droplets":[14,120,252,265],"driven":[15,111,253],"by":[16,121,141,193,254],"coplanar":[17,54],"EWOD":[18,55],"electrodes.":[19],"The":[20,106,167,205,256],"DIBs,":[21],"or":[22],"artificial":[23],"lipid":[25,83,86,108,268],"membranes":[26],"(BLMs),":[27],"are":[28,110,153,176,188,222,238],"fundamental":[29],"to":[30,112,226,271],"the":[31,48,62,78,82,91,94,103,113,117,125,130,132,135,160,164,171,174,191,201,209,217,242,263,267],"in":[32,129,198,241,277,282],"vitro":[33,278],"studies":[34,281],"of":[35,81,93,102,134,173,200,211,262],"purified":[36],"membrane":[37,279],"channel":[38,215],"proteins.":[39],"A":[40],"sandwich":[41],"device":[42,258],"designed":[44],"with":[45,69],"three":[46],"plates:":[47],"top":[49],"and":[50,72,98,139,143,148,163,170,182,208,224,230,266],"bottom":[51],"plates":[52],"contain":[53],"electrodes":[56,147],"for":[57,74,155,276],"individual":[58],"droplet":[60,284],"manipulations;":[61],"middle":[63],"silicon":[64],"plate":[65],"holds":[66],"an":[67],"proper":[70],"dimension":[71],"wettability":[73],"DIB":[75,136,175,192,274],"formation.":[76],"For":[77],"amphiphilic":[79],"characteristic":[80],"molecules,":[84],"monolayer":[87],"assembled":[89],"at":[90,216],"water":[95],"(KCl)":[96],"core":[97,203],"oil":[99,127],"(decane)":[100],"shell":[101],"droplet.":[105,204],"monolayers":[109],"through":[115],"manipulating":[116],"EWOD.":[122,255],"After":[123],"thinning":[124],"excess":[126],"film":[128],"aperture,":[131],"formation":[133,275],"completed":[138],"confirmed":[140],"optical":[142],"electrical":[144],"means.":[145],"Ag/AgCl":[146],"patch":[150],"clamp":[151,220],"amplifier":[152],"used":[154],"electrophysiological":[156],"signal":[157],"examinations,":[158],"including":[159],"transmembrane":[161],"capacitance":[162,169],"ion":[165,206,214,236],"current.":[166],"specific":[168],"thickness":[172],"0.5":[177],"\u03bcF/cm":[178],"<sup":[179],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[180],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>":[181],"6.8":[183],"nm,":[184],"respectively.":[185,233],"Ion":[186],"channels":[187,237],"incorporated":[189,213,240],"into":[190],"adding":[194],"alpha-hemolysin":[195],"(a-HL)":[196],"molecules":[197],"one":[199],"KCl":[202],"current":[207],"conductance":[210],"each":[212],"150":[218],"mV":[219],"voltage":[221],"monitored":[223],"measured":[225],"be":[227],"80":[228],"pA":[229],"500":[231],"pS,":[232],"Around":[234],"10":[235],"successfully":[239],"100":[243,246],"\u03bcm":[244,247],"\u00d7":[245],"demonstrated":[257],"exhibits":[259],"precise":[260],"control":[261],"monolayers,":[269],"contributing":[270],"stable":[273],"proteins":[280],"isolated":[283],"environments.":[285]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}