{"id":"https://openalex.org/W2137914866","doi":"https://doi.org/10.1109/nems.2009.5068565","title":"Synthesis of gold nanoparticles using a vortex-type micro-mixing system","display_name":"Synthesis of gold nanoparticles using a vortex-type micro-mixing system","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2137914866","doi":"https://doi.org/10.1109/nems.2009.5068565","mag":"2137914866"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2009.5068565","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2009.5068565","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045990220","display_name":"Sung-Yi Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Sung-Yi Yang","raw_affiliation_strings":["Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019052583","display_name":"Fong\u2010Yu Cheng","orcid":"https://orcid.org/0000-0002-7826-0676"},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Fong-Yu Cheng","raw_affiliation_strings":["Department of Chemistry, National Cheng Kung University, Tainan, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027993272","display_name":"Chen\u2010Sheng Yeh","orcid":"https://orcid.org/0000-0001-5102-3884"},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chen-Sheng Yeh","raw_affiliation_strings":["Department of Chemistry, National Cheng Kung University, Tainan, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108094728","display_name":"Huan\u2010Yao Lei","orcid":null},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Huan-Yao Lei","raw_affiliation_strings":["Department of Microbiology and Immunology, National Cheng Kung University, Tainan, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007513075","display_name":"Gwo\u2010Bin Lee","orcid":"https://orcid.org/0000-0001-6910-9133"},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]},{"id":"https://openalex.org/I4210148468","display_name":"Industrial Technology Research Institute","ror":"https://ror.org/05szzwt63","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I4210148468"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Gwo-Bin Lee","raw_affiliation_strings":["Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan","Medical Electronics and Device Technology Center, Industrial Technology Research Institute, Hsinchu, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan","institution_ids":["https://openalex.org/I91807558"]},{"raw_affiliation_string":"Medical Electronics and Device Technology Center, Industrial Technology Research Institute, Hsinchu, Taiwan","institution_ids":["https://openalex.org/I4210148468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5045990220"],"corresponding_institution_ids":["https://openalex.org/I91807558"],"apc_list":null,"apc_paid":null,"fwci":0.2223,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.61510425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"227","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.807238757610321},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.7541687488555908},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.750373125076294},{"id":"https://openalex.org/keywords/colloidal-gold","display_name":"Colloidal gold","score":0.7293466329574585},{"id":"https://openalex.org/keywords/mixing","display_name":"Mixing (physics)","score":0.7269991040229797},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.6662889719009399},{"id":"https://openalex.org/keywords/microreactor","display_name":"Microreactor","score":0.4956403970718384},{"id":"https://openalex.org/keywords/vortex","display_name":"Vortex","score":0.4925697445869446},{"id":"https://openalex.org/keywords/reagent","display_name":"Reagent","score":0.46789419651031494},{"id":"https://openalex.org/keywords/micromixer","display_name":"Micromixer","score":0.4628185033798218},{"id":"https://openalex.org/keywords/microfluidic-chip","display_name":"Microfluidic chip","score":0.42814770340919495},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.13392698764801025},{"id":"https://openalex.org/keywords/catalysis","display_name":"Catalysis","score":0.07231888175010681},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.05861958861351013}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.807238757610321},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7541687488555908},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.750373125076294},{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.7293466329574585},{"id":"https://openalex.org/C138777275","wikidata":"https://www.wikidata.org/wiki/Q6884054","display_name":"Mixing (physics)","level":2,"score":0.7269991040229797},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6662889719009399},{"id":"https://openalex.org/C147831808","wikidata":"https://www.wikidata.org/wiki/Q1431442","display_name":"Microreactor","level":3,"score":0.4956403970718384},{"id":"https://openalex.org/C140820882","wikidata":"https://www.wikidata.org/wiki/Q732722","display_name":"Vortex","level":2,"score":0.4925697445869446},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.46789419651031494},{"id":"https://openalex.org/C2780982322","wikidata":"https://www.wikidata.org/wiki/Q3312230","display_name":"Micromixer","level":3,"score":0.4628185033798218},{"id":"https://openalex.org/C2988198817","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Microfluidic chip","level":3,"score":0.42814770340919495},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13392698764801025},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.07231888175010681},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05861958861351013},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nems.2009.5068565","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2009.5068565","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1972148782","https://openalex.org/W2045834797","https://openalex.org/W2077228161","https://openalex.org/W2078206345","https://openalex.org/W2084124931","https://openalex.org/W2126741288","https://openalex.org/W2165270459"],"related_works":["https://openalex.org/W2014213468","https://openalex.org/W2744361580","https://openalex.org/W3213968017","https://openalex.org/W2094324632","https://openalex.org/W4390403920","https://openalex.org/W2075367436","https://openalex.org/W4244444919","https://openalex.org/W2058246061","https://openalex.org/W2356576053","https://openalex.org/W4367182701"],"abstract_inverted_index":{"A":[0],"new":[1],"microfluidic":[2,38,141],"reaction":[3,39,142],"chip":[4,40],"capable":[5,65],"of":[6,15,34,43,66,86,97,114,125,139,148],"mixing,":[7],"transporting":[8],"and":[9,26,46,55,119],"reacting":[10],"is":[11,64,144],"developed":[12],"for":[13,23,146,151],"synthesis":[14,33,85,147],"gold":[16,35,88,108],"nanoparticles":[17,89,109,127,150],"with":[18,134],"tunable":[19],"sizes.":[20],"It":[21],"allows":[22],"a":[24,27,52,56,59,68,74,94],"rapid":[25],"cost-effective":[28],"approach":[29],"to":[30,50,72,103],"accelerate":[31],"the":[32,126,140],"nanoparticles.":[36],"The":[37,62,106,123,137],"was":[41],"made":[42],"CNC":[44],"machining":[45],"PDMS":[47],"casting":[48],"process":[49],"integrate":[51],"vortex-type":[53,69],"micro-mixer":[54,63],"micro-pump":[57],"on":[58],"single":[60],"chip.":[61],"generating":[67],"flow":[70],"field":[71],"achieve":[73],"mixing":[75],"efficiency":[76],"as":[77,79,101],"high":[78],"94%":[80],"within":[81,93],"1":[82],"second.":[83],"Successful":[84],"dispersed":[87,107],"has":[90],"been":[91],"demonstrated":[92],"shorter":[95],"period":[96],"time":[98],"(5":[99],"minutes),":[100],"compared":[102],"traditional":[104],"methods.":[105],"had":[110],"an":[111],"average":[112],"diameter":[113],"17":[115],"nm,":[116,121],"23":[117],"nm":[118],"48":[120],"respectively.":[122],"size":[124],"can":[128],"be":[129],"fine-tuned":[130],"by":[131],"using":[132],"reagents":[133],"different":[135],"volumes.":[136],"development":[138],"system":[143],"promising":[145],"functional":[149],"further":[152],"biomedical":[153],"applications.":[154]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}