{"id":"https://openalex.org/W4214625964","doi":"https://doi.org/10.1109/msp.2021.3126573","title":"Explainable Artificial Intelligence for Magnetic Resonance Imaging Aging Brainprints: Grounds and challenges","display_name":"Explainable Artificial Intelligence for Magnetic Resonance Imaging Aging Brainprints: Grounds and challenges","publication_year":2022,"publication_date":"2022-02-24","ids":{"openalex":"https://openalex.org/W4214625964","doi":"https://doi.org/10.1109/msp.2021.3126573"},"language":"en","primary_location":{"id":"doi:10.1109/msp.2021.3126573","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2021.3126573","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082628560","display_name":"Ilaria Boscolo Galazzo","orcid":"https://orcid.org/0000-0002-4153-3749"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Boscolo Galazzo","raw_affiliation_strings":["Department of Computer Science, University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091352402","display_name":"Federica Cruciani","orcid":"https://orcid.org/0000-0001-7258-1463"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Cruciani","raw_affiliation_strings":["University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003571740","display_name":"Lorenza Brusini","orcid":"https://orcid.org/0000-0001-5357-5180"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorenza Brusini","raw_affiliation_strings":["Department of Computer Science Neuroimaging Lab, University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science Neuroimaging Lab, University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021895255","display_name":"Ahmed Salih","orcid":"https://orcid.org/0000-0002-0871-8282"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ahmed Salih","raw_affiliation_strings":["University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083867344","display_name":"Petia Radeva","orcid":"https://orcid.org/0000-0003-0047-5172"},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Petia Radeva","raw_affiliation_strings":["University of Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074934100","display_name":"Silvia Francesca Storti","orcid":"https://orcid.org/0000-0002-8605-803X"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Silvia Francesca Storti","raw_affiliation_strings":["Department of Computer Science, University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042078827","display_name":"Gloria Menegaz","orcid":"https://orcid.org/0000-0002-6889-3461"},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gloria Menegaz","raw_affiliation_strings":["Department of Computer Science, University of Verona, Verona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Verona, Verona, Italy","institution_ids":["https://openalex.org/I119439378"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.4818,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.93164908,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"39","issue":"2","first_page":"99","last_page":"116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6065723896026611},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5102756023406982},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3547353744506836},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11028337478637695}],"concepts":[{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6065723896026611},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5102756023406982},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3547353744506836},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11028337478637695},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/msp.2021.3126573","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2021.3126573","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/82549","is_oa":false,"landing_page_url":"https://qmro.qmul.ac.uk/xmlui/handle/123456789/82549","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8470115619","display_name":null,"funder_award_id":"2018.0855.2019","funder_id":"https://openalex.org/F4320324084","funder_display_name":"Fondazione Cassa di Risparmio di Verona Vicenza Belluno e Ancona"}],"funders":[{"id":"https://openalex.org/F4320324084","display_name":"Fondazione Cassa di Risparmio di Verona Vicenza Belluno e Ancona","ror":"https://ror.org/04wkyys07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W2113127248","https://openalex.org/W2467047798","https://openalex.org/W2752410016","https://openalex.org/W2766141193","https://openalex.org/W2806974828","https://openalex.org/W2919964601","https://openalex.org/W2927351257","https://openalex.org/W2951042025","https://openalex.org/W2961560364","https://openalex.org/W2976981404","https://openalex.org/W2977685912","https://openalex.org/W2990008890","https://openalex.org/W2990366895","https://openalex.org/W2995959638","https://openalex.org/W3007648700","https://openalex.org/W3009640614","https://openalex.org/W3010138595","https://openalex.org/W3010910782","https://openalex.org/W3015236716","https://openalex.org/W3016088911","https://openalex.org/W3017066732","https://openalex.org/W3021228217","https://openalex.org/W3027625971","https://openalex.org/W3027718029","https://openalex.org/W3033270146","https://openalex.org/W3033423750","https://openalex.org/W3033794115","https://openalex.org/W3047472563","https://openalex.org/W3061342290","https://openalex.org/W3092783643","https://openalex.org/W3094272371","https://openalex.org/W3098786448","https://openalex.org/W3116212359","https://openalex.org/W3116286104","https://openalex.org/W3126007897","https://openalex.org/W3129030047","https://openalex.org/W3138819813","https://openalex.org/W3149253096","https://openalex.org/W3177894841"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Marked":[0],"changes":[1],"occur":[2],"in":[3,102,125],"the":[4,25,28,74,83,86,126,135],"brain":[5,46,89],"during":[6],"people\u2019s":[7],"lives,":[8],"and":[9,41,58,105,117,139],"individual":[10],"rates":[11],"of":[12,27,37,45,88,122,128],"aging":[13,90],"have":[14],"revealed":[15],"pronounced":[16],"differences,":[17],"giving":[18],"rise":[19],"to":[20,66,76,81],"subject-specific":[21],"brainprints":[22],"that":[23],"are":[24,31,79,97],"signature":[26],"brain.":[29],"These":[30],"shaped":[32],"by":[33,55],"a":[34,119],"great":[35],"variety":[36],"factors,":[38],"both":[39],"endogenous":[40],"exogenous.":[42],"Accurate":[43],"predictions":[44,78],"age":[47],"(BA)":[48],"can":[49],"be":[50],"derived":[51],"from":[52],"neuroimaging":[53],"endophenotypes":[54],"using":[56],"machine":[57,130],"deep":[59],"learning":[60,131],"(DL)":[61],"techniques.":[62],"Predictive":[63],"models":[64],"leading":[65],"accurate":[67],"estimates":[68],"while":[69],"revealing":[70],"which":[71],"features":[72],"contribute":[73],"most":[75],"final":[77],"key":[80],"unveiling":[82],"mechanisms":[84],"underlying":[85],"evolution":[87],"patterns.":[91],"Explainable":[92],"artificial":[93],"intelligence":[94],"(XAI)":[95],"methods":[96],"emerging":[98],"as":[99],"enabling":[100],"technology":[101],"different":[103],"fields,":[104],"biomedicine":[106],"is":[107],"no":[108],"exception.":[109],"Within":[110],"this":[111,113],"framework,":[112],"article":[114],"examines":[115],"BA":[116],"presents":[118],"comprehensive":[120],"review":[121],"recent":[123],"advances":[124],"exploitation":[127],"explainable":[129],"(ML)/DL":[132],"methods,":[133],"highlighting":[134],"main":[136],"open":[137],"issues":[138],"providing":[140],"hints":[141],"for":[142],"future":[143],"directions.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":2}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}
