{"id":"https://openalex.org/W2042926996","doi":"https://doi.org/10.1109/msp.2014.2359131","title":"Signal Processing Challenges in Quantitative 3-D Cell Morphology: More than meets the eye","display_name":"Signal Processing Challenges in Quantitative 3-D Cell Morphology: More than meets the eye","publication_year":2014,"publication_date":"2014-12-04","ids":{"openalex":"https://openalex.org/W2042926996","doi":"https://doi.org/10.1109/msp.2014.2359131","mag":"2042926996"},"language":"en","primary_location":{"id":"doi:10.1109/msp.2014.2359131","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2014.2359131","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080519875","display_name":"Alexandre Dufour","orcid":"https://orcid.org/0000-0002-9417-7389"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alexandre Cecilien Dufour","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","BioImage Anal., Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"BioImage Anal., Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028621487","display_name":"Tzu\u2010Yu Liu","orcid":"https://orcid.org/0009-0002-1792-5053"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tzu-Yu Liu","raw_affiliation_strings":["University of California Berkeley, Berkeley, CA, US","Comput. Sci., Univ. of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Berkeley, Berkeley, CA, US","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Comput. Sci., Univ. of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006804831","display_name":"Christel Ducroz","orcid":null},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christel Ducroz","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","BioImage Anal., Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"BioImage Anal., Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088923639","display_name":"Robin Tournemenne","orcid":null},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Robin Tournemenne","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","BioImage Anal., Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"BioImage Anal., Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041718122","display_name":"Beryl Cummings","orcid":null},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beryl Cummings","raw_affiliation_strings":["Duke University, Durham, NC, US","Genome Sci. & Policy, Duke Univ., Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University, Durham, NC, US","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Genome Sci. & Policy, Duke Univ., Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069553925","display_name":"Roman Thibeaux","orcid":"https://orcid.org/0000-0002-4872-0088"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Roman Thibeaux","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","Cell Biol. of Parasitism, Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Cell Biol. of Parasitism, Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049181453","display_name":"Nancy Guill\u00e9n","orcid":"https://orcid.org/0000-0001-6551-9012"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nancy Guillen","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","Cell Biol. of Parasitism, Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Cell Biol. of Parasitism, Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077692655","display_name":"Alfred O. Hero","orcid":"https://orcid.org/0000-0002-2531-9670"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alfred O. Hero","raw_affiliation_strings":["University of Michigan, Ann Arbor, MI, US","EECS, University of Michigan, Ann Arbor-MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan, Ann Arbor, MI, US","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"EECS, University of Michigan, Ann Arbor-MI, USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003562216","display_name":"Jean\u2010Christophe Olivo\u2010Mar\u00edn","orcid":"https://orcid.org/0000-0001-6796-0696"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Christophe Olivo-Marin","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","BioImage Anal., Inst. Pasteur, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"BioImage Anal., Inst. Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.3014,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.93609889,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"32","issue":"1","first_page":"30","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9886000156402588,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7057814598083496},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.5819749236106873},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5036737322807312},{"id":"https://openalex.org/keywords/signal-processing","display_name":"Signal processing","score":0.5006730556488037},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.4310237169265747},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.404785692691803},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3363325595855713},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.18597981333732605},{"id":"https://openalex.org/keywords/digital-signal-processing","display_name":"Digital signal processing","score":0.12891027331352234},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.10787540674209595}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7057814598083496},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.5819749236106873},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5036737322807312},{"id":"https://openalex.org/C104267543","wikidata":"https://www.wikidata.org/wiki/Q208163","display_name":"Signal processing","level":3,"score":0.5006730556488037},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.4310237169265747},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.404785692691803},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3363325595855713},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.18597981333732605},{"id":"https://openalex.org/C84462506","wikidata":"https://www.wikidata.org/wiki/Q173142","display_name":"Digital signal processing","level":2,"score":0.12891027331352234},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.10787540674209595},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/msp.2014.2359131","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2014.2359131","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},{"id":"pmh:oai:HAL:hal-01504210v1","is_oa":false,"landing_page_url":"https://hal.science/hal-01504210","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Signal Processing Magazine, 2014, 32 (1), pp.30 - 40. ⟨10.1109/MSP.2014.2359131⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W1251994293","https://openalex.org/W1534943575","https://openalex.org/W1601795611","https://openalex.org/W1642811002","https://openalex.org/W1968059064","https://openalex.org/W1970480709","https://openalex.org/W1973537206","https://openalex.org/W1978372216","https://openalex.org/W1978377738","https://openalex.org/W1989571703","https://openalex.org/W1995054497","https://openalex.org/W1995899361","https://openalex.org/W2003410902","https://openalex.org/W2012807282","https://openalex.org/W2015446637","https://openalex.org/W2019645677","https://openalex.org/W2028201091","https://openalex.org/W2031813546","https://openalex.org/W2034987376","https://openalex.org/W2037793186","https://openalex.org/W2037947871","https://openalex.org/W2042094955","https://openalex.org/W2043778742","https://openalex.org/W2055034152","https://openalex.org/W2055575746","https://openalex.org/W2055680969","https://openalex.org/W2065455422","https://openalex.org/W2075844130","https://openalex.org/W2080805673","https://openalex.org/W2087133170","https://openalex.org/W2091781764","https://openalex.org/W2092617318","https://openalex.org/W2092877776","https://openalex.org/W2095200344","https://openalex.org/W2096260418","https://openalex.org/W2096897625","https://openalex.org/W2101491865","https://openalex.org/W2102238397","https://openalex.org/W2102872573","https://openalex.org/W2103706175","https://openalex.org/W2105622447","https://openalex.org/W2112946416","https://openalex.org/W2114609172","https://openalex.org/W2116529502","https://openalex.org/W2119848633","https://openalex.org/W2125493690","https://openalex.org/W2126653712","https://openalex.org/W2132304537","https://openalex.org/W2132822444","https://openalex.org/W2134301144","https://openalex.org/W2137594541","https://openalex.org/W2139210474","https://openalex.org/W2140099710","https://openalex.org/W2141273399","https://openalex.org/W2142152320","https://openalex.org/W2145871384","https://openalex.org/W2148512517","https://openalex.org/W2148743296","https://openalex.org/W2156472837","https://openalex.org/W2157033249","https://openalex.org/W2159498975","https://openalex.org/W2159960204","https://openalex.org/W2160041854","https://openalex.org/W2164765928","https://openalex.org/W2167279371","https://openalex.org/W2170740693","https://openalex.org/W2171033594","https://openalex.org/W2171314935","https://openalex.org/W2539842262","https://openalex.org/W2998216295","https://openalex.org/W3149760511","https://openalex.org/W4239328123","https://openalex.org/W4285719527","https://openalex.org/W4319292979","https://openalex.org/W6628200253","https://openalex.org/W6728591343","https://openalex.org/W7066667914"],"related_works":["https://openalex.org/W2012531322","https://openalex.org/W2785900585","https://openalex.org/W2353730437","https://openalex.org/W2490303674","https://openalex.org/W2609066826","https://openalex.org/W2810752900","https://openalex.org/W2365677836","https://openalex.org/W2531295127","https://openalex.org/W2131169870","https://openalex.org/W3014136459"],"abstract_inverted_index":{"Modern":[0],"developments":[1],"in":[2,69,112],"light":[3],"microscopy":[4],"have":[5],"allowed":[6],"the":[7,26,35,44,63,71],"observation":[8],"of":[9,22,62,73],"cell":[10,105],"deformation":[11],"with":[12,79],"remarkable":[13],"spatiotemporal":[14],"resolution":[15],"and":[16,29,49,52,66,87,117],"reproducibility.":[17],"Analyzing":[18],"such":[19],"phenomena":[20],"is":[21],"particular":[23,81],"interest":[24],"for":[25],"signal":[27],"processing":[28],"computer":[30],"vision":[31],"communities":[32],"due":[33],"to":[34,46],"numerous":[36],"computational":[37],"challenges":[38,68],"involved,":[39],"from":[40],"image":[41],"acquisition":[42],"all":[43],"way":[45],"shape":[47,84],"analysis":[48],"pattern":[50],"recognition":[51],"interpretation.":[53],"This":[54],"article":[55],"aims":[56],"at":[57],"providing":[58],"an":[59],"up-to-date":[60],"overview":[61],"problems,":[64],"solutions,":[65],"remaining":[67],"deciphering":[70],"morphology":[72],"living":[74],"cells":[75],"via":[76],"computerized":[77],"approaches,":[78],"a":[80,94],"focus":[82],"on":[83,103],"description":[85],"frameworks":[86],"their":[88],"exploitation":[89],"using":[90],"machine-learning":[91],"techniques.":[92],"As":[93],"concrete":[95],"illustration,":[96],"we":[97],"use":[98],"our":[99],"recently":[100],"acquired":[101],"data":[102],"amoeboid":[104],"deformation,":[106],"motivated":[107],"by":[108],"its":[109],"direct":[110],"implication":[111],"immune":[113],"responses,":[114],"bacterial":[115],"invasion,":[116],"cancer":[118],"metastasis.":[119]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2015,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}