{"id":"https://openalex.org/W2081578499","doi":"https://doi.org/10.1109/msp.2014.2346443","title":"Automated Histology Analysis: Opportunities for signal processing","display_name":"Automated Histology Analysis: Opportunities for signal processing","publication_year":2014,"publication_date":"2014-12-04","ids":{"openalex":"https://openalex.org/W2081578499","doi":"https://doi.org/10.1109/msp.2014.2346443","mag":"2081578499"},"language":"en","primary_location":{"id":"doi:10.1109/msp.2014.2346443","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2014.2346443","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/Automated_Histology_Analysis_Opportunities_for_Signal_Processing/6468389","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006151881","display_name":"Michael T. McCann","orcid":"https://orcid.org/0000-0001-7645-252X"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael T McCann","raw_affiliation_strings":["Department of Biomedical Engineering, Carnegie Mellon University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Carnegie Mellon University","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052936626","display_name":"John A. Ozolek","orcid":"https://orcid.org/0000-0002-7015-6401"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Ozolek","raw_affiliation_strings":["Children's Hospital of Pittsburgh, University of Pittsburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Pittsburgh, University of Pittsburgh","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101828558","display_name":"Carlos A. Castro","orcid":"https://orcid.org/0000-0003-2419-3604"},"institutions":[{"id":"https://openalex.org/I4210097282","display_name":"Magee-Womens Research Institute","ror":"https://ror.org/00rnw4e09","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210097282"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlos A. Castro","raw_affiliation_strings":["Foundation Histology Core, Magee-Womens Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation Histology Core, Magee-Womens Research Institute","institution_ids":["https://openalex.org/I4210097282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053749724","display_name":"Bahram Parvin","orcid":"https://orcid.org/0000-0002-6433-8006"},"institutions":[{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]},{"id":"https://openalex.org/I148283060","display_name":"Lawrence Berkeley National Laboratory","ror":"https://ror.org/02jbv0t02","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I148283060","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bahram Parvin","raw_affiliation_strings":["Lawrence Berkeley National Laboratory, University of Nevada, Reno"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawrence Berkeley National Laboratory, University of Nevada, Reno","institution_ids":["https://openalex.org/I134113660","https://openalex.org/I148283060"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101863660","display_name":"Jelena Kova\u010devi\u0107","orcid":"https://orcid.org/0000-0003-0139-2803"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jelena Kovacevic","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Center for Bioimage Informatics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Center for Bioimage Informatics","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":14.5036,"has_fulltext":false,"cited_by_count":129,"citation_normalized_percentile":{"value":0.98828098,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"32","issue":"1","first_page":"78","last_page":"87"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/digitization","display_name":"Digitization","score":0.7640694379806519},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7563368082046509},{"id":"https://openalex.org/keywords/histology","display_name":"Histology","score":0.5769416689872742},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.4881654381752014},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.48508965969085693},{"id":"https://openalex.org/keywords/digital-pathology","display_name":"Digital pathology","score":0.4752778112888336},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.3955235481262207},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3354598879814148},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2038082480430603},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.08893594145774841}],"concepts":[{"id":"https://openalex.org/C2779308522","wikidata":"https://www.wikidata.org/wiki/Q843958","display_name":"Digitization","level":2,"score":0.7640694379806519},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7563368082046509},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.5769416689872742},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.4881654381752014},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.48508965969085693},{"id":"https://openalex.org/C2777522853","wikidata":"https://www.wikidata.org/wiki/Q5276128","display_name":"Digital pathology","level":2,"score":0.4752778112888336},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3955235481262207},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3354598879814148},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2038082480430603},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.08893594145774841}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1109/msp.2014.2346443","is_oa":false,"landing_page_url":"https://doi.org/10.1109/msp.2014.2346443","pdf_url":null,"source":{"id":"https://openalex.org/S120977877","display_name":"IEEE Signal Processing Magazine","issn_l":"1053-5888","issn":["1053-5888","1558-0792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Signal Processing Magazine","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.844.6714","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.844.6714","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://repository.cmu.edu/cgi/viewcontent.cgi?article%3D1295%26context%3Dece","raw_type":"text"},{"id":"pmh:oai:repository.cmu.edu:ece-1295","is_oa":false,"landing_page_url":"http://repository.cmu.edu/ece/285","pdf_url":null,"source":{"id":"https://openalex.org/S7407050927","display_name":"KiltHub Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Electrical and Computer Engineering","raw_type":"text"},{"id":"pmh:doi:10.1184/r1/6468389","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal contribution"},{"id":"pmh:oai:figshare.com:article/6468389","is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Automated_Histology_Analysis_Opportunities_for_Signal_Processing/6468389","pdf_url":null,"source":{"id":"https://openalex.org/S4306402621","display_name":"INDIGO (University of Illinois at Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39422238","host_organization_name":"University of Illinois Chicago","host_organization_lineage":["https://openalex.org/I39422238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"doi:10.1184/r1/6468389.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1184/r1/6468389.v1","pdf_url":null,"source":{"id":"https://openalex.org/S7407050927","display_name":"KiltHub Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/6468389","is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Automated_Histology_Analysis_Opportunities_for_Signal_Processing/6468389","pdf_url":null,"source":{"id":"https://openalex.org/S4306402621","display_name":"INDIGO (University of Illinois at Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39422238","host_organization_name":"University of Illinois Chicago","host_organization_lineage":["https://openalex.org/I39422238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W6585196","https://openalex.org/W22040386","https://openalex.org/W27508393","https://openalex.org/W803682140","https://openalex.org/W1516417927","https://openalex.org/W1597336200","https://openalex.org/W1878606940","https://openalex.org/W1965224467","https://openalex.org/W1969624577","https://openalex.org/W1975389993","https://openalex.org/W1977653087","https://openalex.org/W1980120028","https://openalex.org/W1982390426","https://openalex.org/W1982513269","https://openalex.org/W1984011311","https://openalex.org/W1984372368","https://openalex.org/W1986724697","https://openalex.org/W2002602158","https://openalex.org/W2006167466","https://openalex.org/W2014676949","https://openalex.org/W2026481965","https://openalex.org/W2037255757","https://openalex.org/W2040414046","https://openalex.org/W2050978844","https://openalex.org/W2057114171","https://openalex.org/W2060324894","https://openalex.org/W2066032304","https://openalex.org/W2071844402","https://openalex.org/W2074079901","https://openalex.org/W2078437730","https://openalex.org/W2079385922","https://openalex.org/W2080971197","https://openalex.org/W2083131640","https://openalex.org/W2083494597","https://openalex.org/W2084185625","https://openalex.org/W2089580584","https://openalex.org/W2103243046","https://openalex.org/W2104967324","https://openalex.org/W2105201875","https://openalex.org/W2105739910","https://openalex.org/W2114404477","https://openalex.org/W2114896680","https://openalex.org/W2117299321","https://openalex.org/W2119653719","https://openalex.org/W2122394460","https://openalex.org/W2125942968","https://openalex.org/W2126846422","https://openalex.org/W2132162500","https://openalex.org/W2132763945","https://openalex.org/W2133287637","https://openalex.org/W2133866056","https://openalex.org/W2142332605","https://openalex.org/W2166581609","https://openalex.org/W2167622944","https://openalex.org/W2970106777","https://openalex.org/W3099404130","https://openalex.org/W6600255830","https://openalex.org/W6635816984"],"related_works":["https://openalex.org/W1539704186","https://openalex.org/W2399890175","https://openalex.org/W3202479762","https://openalex.org/W2480493049","https://openalex.org/W4322582183","https://openalex.org/W4308177873","https://openalex.org/W1937392525","https://openalex.org/W2347632764","https://openalex.org/W2286687623","https://openalex.org/W2353982255"],"abstract_inverted_index":{"Histology":[0],"is":[1,11,58],"the":[2,23,44,59,82],"microscopic":[3],"inspection":[4],"of":[5,27,61,81,85,122,144],"plant":[6],"or":[7,148],"animal":[8],"tissue.":[9],"It":[10],"a":[12,19,70,75,89,103,111,153],"critical":[13],"component":[14],"in":[15],"diagnostic":[16],"medicine":[17],"and":[18,25,32],"tool":[20],"for":[21,36,54,113,135],"studying":[22],"pathogenesis":[24],"biology":[26],"processes":[28],"such":[29],"as":[30],"cancer":[31],"embryogenesis.":[33],"Tissue":[34],"processing":[35],"histology":[37,48],"has":[38],"become":[39],"increasingly":[40],"automated,":[41],"drastically":[42],"increasing":[43],"speed":[45],"at":[46,102],"which":[47],"labs":[49],"can":[50,94,118],"produce":[51],"tissue":[52,86],"slides":[53],"viewing.":[55],"Another":[56],"trend":[57],"digitization":[60],"these":[62,78],"slides,":[63],"allowing":[64],"them":[65],"to":[66],"be":[67,96],"viewed":[68],"on":[69],"computer":[71],"rather":[72],"than":[73],"through":[74],"microscope.":[76],"Despite":[77],"changes,":[79],"much":[80],"routine":[83],"analysis":[84,115],"sections":[87],"remains":[88],"painstaking,":[90],"manual":[91],"task":[92],"that":[93,117,131],"only":[95],"completed":[97],"by":[98],"highly":[99],"trained":[100],"pathologists":[101],"high":[104],"cost":[105],"per":[106],"hour.":[107],"There":[108],"is,":[109],"therefore,":[110],"niche":[112],"image":[114],"methods":[116,126],"automate":[119,129],"some":[120],"aspects":[121],"this":[123],"analysis.":[124],"These":[125],"could":[127],"also":[128],"tasks":[130],"are":[132],"prohibitively":[133],"time-consuming":[134],"humans,":[136],"e.g.,":[137],"discovering":[138],"new":[139],"disease":[140],"markers":[141],"from":[142],"hundreds":[143],"whole-slide":[145],"images":[146],"(WSIs)":[147],"precisely":[149],"quantifying":[150],"tissues":[151],"within":[152],"tumor.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":4}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}
