{"id":"https://openalex.org/W2111634507","doi":"https://doi.org/10.1109/mmsp.2008.4665059","title":"Adaptive fuzzy clustering in constructing parametric images for low SNR functional imaging","display_name":"Adaptive fuzzy clustering in constructing parametric images for low SNR functional imaging","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W2111634507","doi":"https://doi.org/10.1109/mmsp.2008.4665059","mag":"2111634507"},"language":"en","primary_location":{"id":"doi:10.1109/mmsp.2008.4665059","is_oa":false,"landing_page_url":"https://doi.org/10.1109/mmsp.2008.4665059","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 IEEE 10th Workshop on Multimedia Signal Processing","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://ira.lib.polyu.edu.hk/bitstream/10397/1906/1/Wen_et_al_Constructing_Parametric_Image.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023376066","display_name":"Lingfeng Wen","orcid":"https://orcid.org/0000-0001-6413-5666"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I14243506","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98","country_code":"HK","type":"education","lineage":["https://openalex.org/I14243506"]},{"id":"https://openalex.org/I2799732068","display_name":"Royal Prince Alfred Hospital","ror":"https://ror.org/05gpvde20","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799732068"]}],"countries":["AU","HK"],"is_corresponding":false,"raw_author_name":"Lingfeng Wen","raw_affiliation_strings":["Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China","Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hong Kong, China","institution_ids":["https://openalex.org/I14243506"]},{"raw_affiliation_string":"Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia","institution_ids":["https://openalex.org/I2799732068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033497816","display_name":"Stefan Eberl","orcid":"https://orcid.org/0000-0001-6069-7530"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2799732068","display_name":"Royal Prince Alfred Hospital","ror":"https://ror.org/05gpvde20","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799732068"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stefan Eberl","raw_affiliation_strings":["Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia","institution_ids":["https://openalex.org/I2799732068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082979981","display_name":"Michael Fulham","orcid":"https://orcid.org/0000-0003-0602-6319"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2799732068","display_name":"Royal Prince Alfred Hospital","ror":"https://ror.org/05gpvde20","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799732068"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael Fulham","raw_affiliation_strings":["Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia","Faculty of Medicine, University of Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia","institution_ids":["https://openalex.org/I2799732068"]},{"raw_affiliation_string":"Faculty of Medicine, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068891693","display_name":"Dagan Feng","orcid":"https://orcid.org/0000-0002-3381-214X"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2799732068","display_name":"Royal Prince Alfred Hospital","ror":"https://ror.org/05gpvde20","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799732068"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dagan Feng","raw_affiliation_strings":["Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]},{"raw_affiliation_string":"Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, Australia","institution_ids":["https://openalex.org/I2799732068"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100746164","display_name":"Jing Bai","orcid":"https://orcid.org/0000-0001-5412-7793"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Bai","raw_affiliation_strings":["Department of Biomedical Engineering, Tsinghua University, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tsinghua University, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20197348,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"117","last_page":"121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9801999926567078,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7276597619056702},{"id":"https://openalex.org/keywords/normalization","display_name":"Normalization (sociology)","score":0.6991487145423889},{"id":"https://openalex.org/keywords/parametric-statistics","display_name":"Parametric statistics","score":0.698755145072937},{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.6775537729263306},{"id":"https://openalex.org/keywords/fuzzy-logic","display_name":"Fuzzy logic","score":0.6444690227508545},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6364038586616516},{"id":"https://openalex.org/keywords/fuzzy-clustering","display_name":"Fuzzy clustering","score":0.5665902495384216},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5427027940750122},{"id":"https://openalex.org/keywords/monte-carlo-method","display_name":"Monte Carlo method","score":0.4651442766189575},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.461518257856369},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.42469435930252075},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.4200842082500458},{"id":"https://openalex.org/keywords/signal-to-noise-ratio","display_name":"Signal-to-noise ratio (imaging)","score":0.4155097007751465},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.41309213638305664},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2752847671508789},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.2563222646713257},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.16006618738174438}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7276597619056702},{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.6991487145423889},{"id":"https://openalex.org/C117251300","wikidata":"https://www.wikidata.org/wiki/Q1849855","display_name":"Parametric statistics","level":2,"score":0.698755145072937},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.6775537729263306},{"id":"https://openalex.org/C58166","wikidata":"https://www.wikidata.org/wiki/Q224821","display_name":"Fuzzy logic","level":2,"score":0.6444690227508545},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6364038586616516},{"id":"https://openalex.org/C17212007","wikidata":"https://www.wikidata.org/wiki/Q5511111","display_name":"Fuzzy clustering","level":3,"score":0.5665902495384216},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5427027940750122},{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.4651442766189575},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.461518257856369},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.42469435930252075},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.4200842082500458},{"id":"https://openalex.org/C13944312","wikidata":"https://www.wikidata.org/wiki/Q7512748","display_name":"Signal-to-noise ratio (imaging)","level":2,"score":0.4155097007751465},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.41309213638305664},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2752847671508789},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.2563222646713257},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.16006618738174438},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/mmsp.2008.4665059","is_oa":false,"landing_page_url":"https://doi.org/10.1109/mmsp.2008.4665059","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 IEEE 10th Workshop on Multimedia Signal Processing","raw_type":"proceedings-article"},{"id":"pmh:oai:ira.lib.polyu.edu.hk:10397/1906","is_oa":true,"landing_page_url":"http://hdl.handle.net/10397/1906","pdf_url":"http://ira.lib.polyu.edu.hk/bitstream/10397/1906/1/Wen_et_al_Constructing_Parametric_Image.pdf","source":{"id":"https://openalex.org/S4306400205","display_name":"PolyU Institutional Research Archive (Hong Kong Polytechnic University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I14243506","host_organization_name":"Hong Kong Polytechnic University","host_organization_lineage":["https://openalex.org/I14243506"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference Paper"}],"best_oa_location":{"id":"pmh:oai:ira.lib.polyu.edu.hk:10397/1906","is_oa":true,"landing_page_url":"http://hdl.handle.net/10397/1906","pdf_url":"http://ira.lib.polyu.edu.hk/bitstream/10397/1906/1/Wen_et_al_Constructing_Parametric_Image.pdf","source":{"id":"https://openalex.org/S4306400205","display_name":"PolyU Institutional Research Archive (Hong Kong Polytechnic University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I14243506","host_organization_name":"Hong Kong Polytechnic University","host_organization_lineage":["https://openalex.org/I14243506"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference Paper"},"sustainable_development_goals":[{"score":0.5099999904632568,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322598","display_name":"Hong Kong Polytechnic University","ror":"https://ror.org/0030zas98"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2111634507.pdf","grobid_xml":"https://content.openalex.org/works/W2111634507.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W30668343","https://openalex.org/W149814209","https://openalex.org/W565818782","https://openalex.org/W1972193165","https://openalex.org/W1974540670","https://openalex.org/W1992419399","https://openalex.org/W1996023182","https://openalex.org/W2036536353","https://openalex.org/W2095897724","https://openalex.org/W2108707886","https://openalex.org/W2112155856","https://openalex.org/W2115212575","https://openalex.org/W2120277106","https://openalex.org/W2149779354","https://openalex.org/W2153233077","https://openalex.org/W2154744699","https://openalex.org/W2161281052","https://openalex.org/W2166432026","https://openalex.org/W2167399681","https://openalex.org/W2798763302","https://openalex.org/W4285719527","https://openalex.org/W6601256463","https://openalex.org/W6605953855","https://openalex.org/W6659642488"],"related_works":["https://openalex.org/W3027020613","https://openalex.org/W2016533837","https://openalex.org/W2591697403","https://openalex.org/W3167885074","https://openalex.org/W2892386716","https://openalex.org/W1998563493","https://openalex.org/W2944728705","https://openalex.org/W4306164210","https://openalex.org/W2904022177","https://openalex.org/W4313316311"],"abstract_inverted_index":{"Functional":[0],"imaging":[1],"can":[2],"provide":[3],"quantitative":[4,80],"functional":[5,18],"parameters":[6],"to":[7,13,36,46,65,73,122,133],"aid":[8],"early":[9],"diagnosis.":[10],"Low":[11],"signal":[12],"noise":[14],"ratio":[15],"(SNR)":[16],"in":[17,30,115],"imaging,":[19],"especially":[20],"for":[21,82,136],"single":[22],"photon":[23],"emission":[24],"computed":[25],"tomography,":[26],"poses":[27],"a":[28],"challenge":[29],"generating":[31],"voxel-wise":[32],"parametric":[33,117],"images":[34,118],"due":[35],"unreliable":[37],"or":[38],"physiologically":[39],"meaningless":[40],"parameter":[41],"estimates.":[42],"Our":[43],"aim":[44],"was":[45],"systematically":[47],"investigate":[48],"the":[49,83,86],"performance":[50],"of":[51,126],"our":[52],"recently":[53],"proposed":[54],"adaptive":[55],"fuzzy":[56,63,113],"clustering":[57,64,114],"(AFC)":[58],"technique,":[59],"which":[60],"applies":[61],"standard":[62,112],"sub-divided":[66],"data.":[67],"Monte":[68],"Carlo":[69],"simulations":[70],"were":[71],"performed":[72],"generate":[74],"noisy":[75],"dynamic":[76],"SPECT":[77],"data":[78],"with":[79],"analysis":[81],"fitting":[84],"using":[85],"general":[87],"linear":[88],"least":[89],"square":[90],"method":[91],"(GLLS)":[92],"and":[93,107],"enhanced":[94],"model-aided":[95],"GLLS":[96],"methods.":[97],"The":[98],"results":[99],"show":[100],"that":[101],"AFC":[102,140],"substantially":[103],"improves":[104],"computational":[105],"efficiency":[106],"obtains":[108],"improved":[109],"reliability":[110],"as":[111],"estimating":[116],"but":[119],"is":[120,141],"prone":[121],"slight":[123],"underestimation.":[124],"Normalization":[125],"tissue":[127],"time":[128],"activity":[129],"curves":[130],"may":[131],"lead":[132],"severe":[134],"overestimation":[135],"small":[137],"structures":[138],"when":[139],"applied.":[142]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}