{"id":"https://openalex.org/W4405755746","doi":"https://doi.org/10.1109/metroxraine62247.2024.10796585","title":"An Explainable Approach for Early Diagnosis of Parkinson's Disease Exploring Motor Symptoms","display_name":"An Explainable Approach for Early Diagnosis of Parkinson's Disease Exploring Motor Symptoms","publication_year":2024,"publication_date":"2024-10-21","ids":{"openalex":"https://openalex.org/W4405755746","doi":"https://doi.org/10.1109/metroxraine62247.2024.10796585"},"language":"en","primary_location":{"id":"doi:10.1109/metroxraine62247.2024.10796585","is_oa":false,"landing_page_url":"https://doi.org/10.1109/metroxraine62247.2024.10796585","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Metrology for eXtended Reality, Artificial Intelligence and Neural Engineering (MetroXRAINE)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021224978","display_name":"Lerina Aversano","orcid":"https://orcid.org/0000-0003-2436-6835"},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lerina Aversano","raw_affiliation_strings":["University of Foggia,Department of Agricultural, Food, Natural Resources and Engineering Sciences,Foggia,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Foggia,Department of Agricultural, Food, Natural Resources and Engineering Sciences,Foggia,Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092571290","display_name":"Antonella Madau","orcid":null},"institutions":[{"id":"https://openalex.org/I16337185","display_name":"University of Sannio","ror":"https://ror.org/04vc81p87","country_code":"IT","type":"education","lineage":["https://openalex.org/I16337185"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonella Madau","raw_affiliation_strings":["University of Sannio,Dept. of Engineering,Benevento,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Sannio,Dept. of Engineering,Benevento,Italy","institution_ids":["https://openalex.org/I16337185"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068404222","display_name":"Debora Montano","orcid":"https://orcid.org/0000-0002-5598-0822"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Debora Montano","raw_affiliation_strings":["Regional Center Information Communication Technology,CeRICT scrl,Benevento,Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regional Center Information Communication Technology,CeRICT scrl,Benevento,Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35826342,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"855","last_page":"860"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9383999705314636,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9383999705314636,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9309999942779541,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/motor-symptoms","display_name":"Motor symptoms","score":0.5820236206054688},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5431392192840576},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.5401638150215149},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.4936607778072357},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42327994108200073},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.41475000977516174},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3393983542919159},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.29823625087738037},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1018470823764801}],"concepts":[{"id":"https://openalex.org/C3018987647","wikidata":"https://www.wikidata.org/wiki/Q3221083","display_name":"Motor symptoms","level":4,"score":0.5820236206054688},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5431392192840576},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.5401638150215149},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4936607778072357},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42327994108200073},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41475000977516174},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3393983542919159},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.29823625087738037},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1018470823764801}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/metroxraine62247.2024.10796585","is_oa":false,"landing_page_url":"https://doi.org/10.1109/metroxraine62247.2024.10796585","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Metrology for eXtended Reality, Artificial Intelligence and Neural Engineering (MetroXRAINE)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5400000214576721,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1988494453","https://openalex.org/W2053097986","https://openalex.org/W2123714584","https://openalex.org/W2148143831","https://openalex.org/W2961064073","https://openalex.org/W3036689927","https://openalex.org/W3046238651","https://openalex.org/W3092273386","https://openalex.org/W4206062903","https://openalex.org/W4211123396","https://openalex.org/W4281990723","https://openalex.org/W4294559022","https://openalex.org/W4312270979","https://openalex.org/W4312348909","https://openalex.org/W4360604552","https://openalex.org/W4376141987","https://openalex.org/W4379740280","https://openalex.org/W4383645869","https://openalex.org/W4388760453"],"related_works":["https://openalex.org/W3134596587","https://openalex.org/W3216329096","https://openalex.org/W3113736494","https://openalex.org/W2416973532","https://openalex.org/W3116665257","https://openalex.org/W2011324577","https://openalex.org/W3117140735","https://openalex.org/W3118175407","https://openalex.org/W4300409703","https://openalex.org/W2775767512"],"abstract_inverted_index":{"Parkinson's":[0,61,171],"disease":[1,6,62,79,94,163],"is":[2,20,63,68],"a":[3,24,89],"progressive":[4,25],"neurodegen-erative":[5],"that":[7,105,184],"affects":[8],"the":[9,30,34,43,52,58,78,129,132,135,142,153,157,160,170,182,186],"nervous":[10],"system":[11],"causing":[12],"severe":[13],"cognitive,":[14],"motor,":[15],"and":[16,37,54,76,84,96,110],"behavioral":[17],"dysfunctions.":[18],"It":[19],"mainly":[21],"caused":[22],"by":[23,116,127],"loss":[26],"of":[27,45,60,144,159],"neurons":[28],"in":[29,33,42,74],"substantia":[31],"nigra":[32],"basal":[35],"ganglia":[36],"this":[38,56],"leads":[39],"to":[40,70,92,107],"abnormalities":[41],"control":[44],"movements.":[46],"The":[47,146,165],"symptoms":[48],"progress":[49,99],"slowly":[50],"over":[51],"years":[53],"for":[55,113,162],"reason,":[57],"diagnosis":[59],"very":[64],"complex,":[65],"so":[66],"it":[67],"important":[69],"support":[71],"medical":[72],"personnel":[73],"identifying":[75],"predicting":[77],"with":[80,131,151],"Artificial":[81,102],"Intelligence":[82,103],"tools":[83],"techniques.":[85],"This":[86],"study":[87],"proposes":[88],"new":[90],"approach":[91],"predict":[93],"onset":[95],"monitor":[97],"patient":[98],"through":[100,141],"Explainable":[101],"(XAI)":[104],"aims":[106],"provide":[108],"clear":[109],"understandable":[111],"explanations":[112],"decisions":[114],"made":[115],"machine":[117],"learning":[118],"algorithms.":[119],"Initially,":[120],"different":[121],"classification":[122],"algorithms":[123],"were":[124,139],"evaluated":[125],"and,":[126],"choosing":[128],"one":[130],"best":[133],"performance,":[134],"most":[136],"significant":[137],"features":[138],"identified":[140],"use":[143,158],"SHAP.":[145],"model":[147],"was":[148,167],"subsequently":[149],"re-evaluated":[150],"only":[152,181],"selected":[154],"features,":[155],"evaluating":[156],"XAI":[161],"identification.":[164],"methodology":[166],"validated":[168],"on":[169],"Progression":[172],"Markers":[173],"Initiative":[174],"(PPMI),":[175],"more":[176],"specifically":[177],"taking":[178],"into":[179],"consideration":[180],"characteristics":[183],"concern":[185],"motor":[187],"sphere.":[188]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}