{"id":"https://openalex.org/W2968485268","doi":"https://doi.org/10.1109/memea.2019.8802132","title":"Highly Linear Amperometric Glucose Detection System Realized in Deep Submicron CMOS Technology","display_name":"Highly Linear Amperometric Glucose Detection System Realized in Deep Submicron CMOS Technology","publication_year":2019,"publication_date":"2019-06-01","ids":{"openalex":"https://openalex.org/W2968485268","doi":"https://doi.org/10.1109/memea.2019.8802132","mag":"2968485268"},"language":"en","primary_location":{"id":"doi:10.1109/memea.2019.8802132","is_oa":false,"landing_page_url":"https://doi.org/10.1109/memea.2019.8802132","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082579923","display_name":"Hanfeng Wang","orcid":"https://orcid.org/0000-0002-8819-318X"},"institutions":[{"id":"https://openalex.org/I75027704","display_name":"University of Tennessee at Knoxville","ror":"https://ror.org/020f3ap87","country_code":"US","type":"education","lineage":["https://openalex.org/I75027704"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hanfeng Wang","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN","institution_ids":["https://openalex.org/I75027704"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051013059","display_name":"Samira Shamsir","orcid":"https://orcid.org/0000-0003-1311-8270"},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samira Shamsir","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041993740","display_name":"Ifana Mahbub","orcid":"https://orcid.org/0000-0002-5561-0880"},"institutions":[{"id":"https://openalex.org/I123534392","display_name":"University of North Texas","ror":"https://ror.org/00v97ad02","country_code":"US","type":"education","lineage":["https://openalex.org/I123534392"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ifana Mahbub","raw_affiliation_strings":["Department of Electrical Engineering, University of North Texas, Denton, TX"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of North Texas, Denton, TX","institution_ids":["https://openalex.org/I123534392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062878427","display_name":"Syed K. Islam","orcid":"https://orcid.org/0000-0002-0501-0027"},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Syed K. Islam","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029437739","display_name":"Allen Legassey","orcid":"https://orcid.org/0009-0002-0814-7472"},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allen Legassey","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT","institution_ids":["https://openalex.org/I140172145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110632729","display_name":"Raja Hari Gudlavelleti","orcid":null},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raja Hari Gudlavelleti","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT","institution_ids":["https://openalex.org/I140172145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083216962","display_name":"Fotios Papadimitrakopoulos","orcid":null},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fotios Papadimitrakopoulos","raw_affiliation_strings":["Department of Chemistry, University of Connecticut, Storrs, CT"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Connecticut, Storrs, CT","institution_ids":["https://openalex.org/I140172145"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061990217","display_name":"F. Jain","orcid":"https://orcid.org/0000-0003-3961-6665"},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Faquir Jain","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT","institution_ids":["https://openalex.org/I140172145"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5082579923"],"corresponding_institution_ids":["https://openalex.org/I75027704"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.11526896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/potentiostat","display_name":"Potentiostat","score":0.9137436151504517},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.805689811706543},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.6791040897369385},{"id":"https://openalex.org/keywords/application-specific-integrated-circuit","display_name":"Application-specific integrated circuit","score":0.6118350625038147},{"id":"https://openalex.org/keywords/amperometry","display_name":"Amperometry","score":0.5580148696899414},{"id":"https://openalex.org/keywords/linearity","display_name":"Linearity","score":0.5407898426055908},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.45065662264823914},{"id":"https://openalex.org/keywords/system-of-measurement","display_name":"System of measurement","score":0.44256120920181274},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.4312842786312103},{"id":"https://openalex.org/keywords/footprint","display_name":"Footprint","score":0.42481040954589844},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.4103180170059204},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4071948230266571},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35254019498825073},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.32353436946868896},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.25501447916030884},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.23027241230010986},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.21786195039749146},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.17853856086730957},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.17092138528823853},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09552326798439026}],"concepts":[{"id":"https://openalex.org/C2779995598","wikidata":"https://www.wikidata.org/wiki/Q629290","display_name":"Potentiostat","level":4,"score":0.9137436151504517},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.805689811706543},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.6791040897369385},{"id":"https://openalex.org/C77390884","wikidata":"https://www.wikidata.org/wiki/Q217302","display_name":"Application-specific integrated circuit","level":2,"score":0.6118350625038147},{"id":"https://openalex.org/C139369640","wikidata":"https://www.wikidata.org/wiki/Q474536","display_name":"Amperometry","level":4,"score":0.5580148696899414},{"id":"https://openalex.org/C77170095","wikidata":"https://www.wikidata.org/wiki/Q1753188","display_name":"Linearity","level":2,"score":0.5407898426055908},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.45065662264823914},{"id":"https://openalex.org/C37649242","wikidata":"https://www.wikidata.org/wiki/Q932268","display_name":"System of measurement","level":2,"score":0.44256120920181274},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.4312842786312103},{"id":"https://openalex.org/C132943942","wikidata":"https://www.wikidata.org/wiki/Q2562511","display_name":"Footprint","level":2,"score":0.42481040954589844},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.4103180170059204},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4071948230266571},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35254019498825073},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.32353436946868896},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.25501447916030884},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.23027241230010986},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.21786195039749146},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17853856086730957},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.17092138528823853},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09552326798439026},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/memea.2019.8802132","is_oa":false,"landing_page_url":"https://doi.org/10.1109/memea.2019.8802132","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy","score":0.8799999952316284}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1013120588","https://openalex.org/W1970975244","https://openalex.org/W1971775068","https://openalex.org/W1973279852","https://openalex.org/W1980884957","https://openalex.org/W1989157562","https://openalex.org/W2034718383","https://openalex.org/W2060323122","https://openalex.org/W2062011845","https://openalex.org/W2068773777","https://openalex.org/W2073243905","https://openalex.org/W2102375473","https://openalex.org/W2128508216","https://openalex.org/W2133849398","https://openalex.org/W2146524624","https://openalex.org/W2158178644","https://openalex.org/W2161313513","https://openalex.org/W2161811052","https://openalex.org/W2367834128","https://openalex.org/W2469510328","https://openalex.org/W3149729898"],"related_works":["https://openalex.org/W2051207682","https://openalex.org/W4319875893","https://openalex.org/W3035104883","https://openalex.org/W1986208677","https://openalex.org/W2757875722","https://openalex.org/W2096951988","https://openalex.org/W2897418078","https://openalex.org/W2559042708","https://openalex.org/W2070359565","https://openalex.org/W1024889183"],"abstract_inverted_index":{"The":[0,110],"aim":[1],"of":[2,15,75,80,82,90,131],"this":[3],"work":[4],"is":[5,27,66,113],"to":[6,41,47,70,98],"realize":[7],"a":[8,38,43,61,91,120],"needle":[9],"implantable":[10],"biosensor":[11,40,77],"for":[12],"continuous":[13],"monitoring":[14],"interstitial":[16],"glucose":[17,39,49,83],"levels.":[18],"A":[19,52],"highly":[20],"miniaturized":[21],"application":[22],"specific":[23],"integrated":[24],"circuit":[25],"(ASIC)":[26],"designed":[28,67],"using":[29],"130":[30],"nm":[31],"standard":[32],"CMOS":[33],"technology":[34],"and":[35,60,68,127],"combined":[36],"with":[37,101,115],"produce":[42],"frequency":[44],"signal":[45,62],"proportional":[46],"the":[48,73,76,102],"concentration":[50],"level.":[51],"prototype":[53,86],"system":[54,87,112],"incorporating":[55],"an":[56],"on-chip":[57],"amperometric":[58],"potentiostat":[59],"processing":[63],"unit":[64],"(SPU)":[65],"implemented":[69],"amperiometrically":[71],"assess":[72],"performance":[74],"in":[78],"term":[79],"measurement":[81,89],"values.":[84],"This":[85],"demonstrated":[88],"wide":[92],"current":[93],"range":[94],"from":[95],"1":[96],"nA":[97],"10":[99],"\u03bcA":[100],"output":[103],"read-out":[104],"exhibiting":[105],"linearity":[106],"higher":[107],"than":[108],"99%.":[109],"realized":[111],"optimized":[114],"small":[116],"physical":[117],"footprint":[118],"occupying":[119],"1.5":[121],"mm":[122,125],"\u00d7":[123],"0.439":[124],"die":[126],"maximum":[128],"power":[129],"consumption":[130],"about":[132],"80":[133],"\u03bcW.":[134]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}