{"id":"https://openalex.org/W2739025351","doi":"https://doi.org/10.1109/med.2017.7984124","title":"Automatic artificial ventilation therapy using the ARDSNet protocol enforcing dynamical constraints","display_name":"Automatic artificial ventilation therapy using the ARDSNet protocol enforcing dynamical constraints","publication_year":2017,"publication_date":"2017-07-01","ids":{"openalex":"https://openalex.org/W2739025351","doi":"https://doi.org/10.1109/med.2017.7984124","mag":"2739025351"},"language":"en","primary_location":{"id":"doi:10.1109/med.2017.7984124","is_oa":false,"landing_page_url":"https://doi.org/10.1109/med.2017.7984124","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 25th Mediterranean Conference on Control and Automation (MED)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110061466","display_name":"Anake Pomprapa","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Anake Pomprapa","raw_affiliation_strings":["Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany"],"affiliations":[{"raw_affiliation_string":"Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067033755","display_name":"Philipp A. Pickerodt","orcid":"https://orcid.org/0000-0001-5875-8250"},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"funder","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Philipp A. Pickerodt","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054773768","display_name":"Wolfgang Braun","orcid":"https://orcid.org/0009-0002-7169-4292"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang Braun","raw_affiliation_strings":["Fritz Stephan GmbH, Gackenbach, Germany"],"affiliations":[{"raw_affiliation_string":"Fritz Stephan GmbH, Gackenbach, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038971858","display_name":"Martin Ru\u00df","orcid":"https://orcid.org/0000-0003-4719-2452"},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"funder","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Russ","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112620077","display_name":"Moritz Benjamin Teja Hofferberth","orcid":null},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"funder","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Moritz B.T. Hofferberth","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088575199","display_name":"Marian Walter","orcid":"https://orcid.org/0000-0003-4137-5370"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marian Walter","raw_affiliation_strings":["Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany"],"affiliations":[{"raw_affiliation_string":"Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091171924","display_name":"Berno J.E. Misgeld","orcid":"https://orcid.org/0000-0001-5989-0894"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Berno Misgeld","raw_affiliation_strings":["Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany"],"affiliations":[{"raw_affiliation_string":"Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044444546","display_name":"Roland C. E. Francis","orcid":"https://orcid.org/0000-0003-1958-9364"},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"funder","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Roland C.E. Francis","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111848788","display_name":"Burkhard Lachmann","orcid":null},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"funder","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Burkhard Lachmann","raw_affiliation_strings":["Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Intensive Care Medicine, Charite-University Medicine, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060021065","display_name":"Steffen Leonhardt","orcid":"https://orcid.org/0000-0002-6898-6887"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Leonhardt","raw_affiliation_strings":["Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany"],"affiliations":[{"raw_affiliation_string":"Chair of Medical Information Technology, RWTH Aachen University, Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5110061466"],"corresponding_institution_ids":["https://openalex.org/I887968799"],"apc_list":null,"apc_paid":null,"fwci":0.2048,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.59139752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"68","issue":null,"first_page":"235","last_page":"240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9860000014305115,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ards","display_name":"ARDS","score":0.9006880521774292},{"id":"https://openalex.org/keywords/acute-respiratory-distress","display_name":"Acute respiratory distress","score":0.6258624792098999},{"id":"https://openalex.org/keywords/ventilation","display_name":"Ventilation (architecture)","score":0.6246873736381531},{"id":"https://openalex.org/keywords/fraction-of-inspired-oxygen","display_name":"Fraction of inspired oxygen","score":0.5679202079772949},{"id":"https://openalex.org/keywords/protocol","display_name":"Protocol (science)","score":0.5414696931838989},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5084692239761353},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"Mechanical ventilation","score":0.4251345992088318},{"id":"https://openalex.org/keywords/artificial-ventilation","display_name":"Artificial ventilation","score":0.42409682273864746},{"id":"https://openalex.org/keywords/oxygenation","display_name":"Oxygenation","score":0.4218299686908722},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.31814414262771606},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.2071431577205658},{"id":"https://openalex.org/keywords/lung","display_name":"Lung","score":0.1974148154258728},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1365106701850891},{"id":"https://openalex.org/keywords/respiratory-disease","display_name":"Respiratory disease","score":0.09258115291595459}],"concepts":[{"id":"https://openalex.org/C2776348555","wikidata":"https://www.wikidata.org/wiki/Q344873","display_name":"ARDS","level":3,"score":0.9006880521774292},{"id":"https://openalex.org/C2909621147","wikidata":"https://www.wikidata.org/wiki/Q344873","display_name":"Acute respiratory distress","level":3,"score":0.6258624792098999},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.6246873736381531},{"id":"https://openalex.org/C2780807750","wikidata":"https://www.wikidata.org/wiki/Q5477511","display_name":"Fraction of inspired oxygen","level":3,"score":0.5679202079772949},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.5414696931838989},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5084692239761353},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.4251345992088318},{"id":"https://openalex.org/C2777387402","wikidata":"https://www.wikidata.org/wiki/Q545991","display_name":"Artificial ventilation","level":4,"score":0.42409682273864746},{"id":"https://openalex.org/C70289976","wikidata":"https://www.wikidata.org/wiki/Q17143603","display_name":"Oxygenation","level":2,"score":0.4218299686908722},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31814414262771606},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2071431577205658},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.1974148154258728},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1365106701850891},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.09258115291595459},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/med.2017.7984124","is_oa":false,"landing_page_url":"https://doi.org/10.1109/med.2017.7984124","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 25th Mediterranean Conference on Control and Automation (MED)","raw_type":"proceedings-article"},{"id":"pmh:oai:publications.rwth-aachen.de:710862","is_oa":false,"landing_page_url":"https://publications.rwth-aachen.de/record/710862","pdf_url":null,"source":{"id":"https://openalex.org/S4306401033","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"[Piscataway, NJ] : IEEE 235-240 (2017). doi:10.1109/MED.2017.7984124","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7799999713897705,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1803784511","https://openalex.org/W1974404062","https://openalex.org/W1982338176","https://openalex.org/W2015305844","https://openalex.org/W2033299686","https://openalex.org/W2035314463","https://openalex.org/W2042782991","https://openalex.org/W2056559632","https://openalex.org/W2059853297","https://openalex.org/W2082841424","https://openalex.org/W2092367700","https://openalex.org/W2138926201","https://openalex.org/W2139110166","https://openalex.org/W2147782759","https://openalex.org/W2161328469","https://openalex.org/W2169732472","https://openalex.org/W2270590048","https://openalex.org/W2338278109","https://openalex.org/W2342102222","https://openalex.org/W2593451995","https://openalex.org/W2597070792","https://openalex.org/W6703504181","https://openalex.org/W6734318641","https://openalex.org/W6996902813"],"related_works":["https://openalex.org/W361746133","https://openalex.org/W3109505888","https://openalex.org/W2058958688","https://openalex.org/W2493937886","https://openalex.org/W2325461875","https://openalex.org/W2335616073","https://openalex.org/W103021685","https://openalex.org/W2329701331","https://openalex.org/W3013904011","https://openalex.org/W2781222976"],"abstract_inverted_index":{"In":[0],"this":[1],"work,":[2],"a":[3,114],"medical":[4],"expert":[5],"system":[6],"is":[7,78,102],"further":[8],"developed":[9],"for":[10,83,89],"automatic":[11,84],"ventilation":[12,88,124],"therapy":[13],"based":[14],"on":[15,55,113],"the":[16,29,90,99],"well-known":[17],"ARDSNet":[18],"protocol":[19],"by":[20],"imposing":[21],"additional":[22,81],"dynamical":[23],"constraints.":[24],"This":[25],"protocol-driven":[26],"approach":[27],"strengthens":[28],"overall":[30],"treatment":[31,91],"of":[32,40,47,62,86,92],"patients":[33],"with":[34,118],"acute":[35,93],"lung":[36],"injury":[37],"in":[38,104],"terms":[39],"improving":[41],"oxygenation":[42],"dynamics.":[43],"The":[44,75],"proposed":[45,100],"dynamics":[46],"quick":[48],"action":[49],"and":[50,70],"long":[51],"idleness":[52],"are":[53],"introduced":[54],"two":[56],"independent":[57],"ventilatory":[58],"variables,":[59],"namely":[60],"fraction":[61],"inspiratory":[63],"oxygen":[64],"(FiO":[65],"<sub":[66],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[67],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[68],")":[69],"positive":[71],"end-expiratory":[72],"pressure":[73],"(PEEP).":[74],"therapeutic":[76],"algorithm":[77,101],"realizable":[79],"forming":[80],"rules":[82],"control":[85],"artificial":[87],"respiratory":[94],"distress":[95],"syndrome":[96],"(ARDS).":[97],"Furthermore,":[98],"applicable":[103],"real":[105],"clinical":[106],"practice.":[107],"A":[108],"validation":[109],"test":[110],"was":[111],"performed":[112],"52-kg":[115],"induced-ARDS":[116],"pig":[117],"outstanding":[119],"results":[120],"to":[121],"meet":[122],"all":[123],"goals.":[125]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}