{"id":"https://openalex.org/W4285117752","doi":"https://doi.org/10.1109/lra.2022.3183253","title":"Modeling of Critically Ill Patient Pathways to Support Intensive Care Delivery","display_name":"Modeling of Critically Ill Patient Pathways to Support Intensive Care Delivery","publication_year":2022,"publication_date":"2022-06-15","ids":{"openalex":"https://openalex.org/W4285117752","doi":"https://doi.org/10.1109/lra.2022.3183253"},"language":"en","primary_location":{"id":"doi:10.1109/lra.2022.3183253","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lra.2022.3183253","pdf_url":null,"source":{"id":"https://openalex.org/S4210169774","display_name":"IEEE Robotics and Automation Letters","issn_l":"2377-3766","issn":["2377-3766"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Robotics and Automation Letters","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019313726","display_name":"William Trevena","orcid":"https://orcid.org/0000-0001-7011-6867"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William Trevena","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079119849","display_name":"Amos Lal","orcid":"https://orcid.org/0000-0002-0021-2033"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amos Lal","raw_affiliation_strings":["Mayo Clinic, Rochester, MN, USA"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050123798","display_name":"Simon Zec","orcid":"https://orcid.org/0000-0002-4353-8535"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simon Zec","raw_affiliation_strings":["Mayo Clinic, Rochester, MN, USA"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022740901","display_name":"Edin Cubro","orcid":null},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edin Cubro","raw_affiliation_strings":["Mayo Clinic, Rochester, MN, USA"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018562621","display_name":"Xiang Zhong","orcid":"https://orcid.org/0000-0002-6214-5876"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiang Zhong","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077832390","display_name":"Yue Dong","orcid":"https://orcid.org/0000-0002-1737-6536"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yue Dong","raw_affiliation_strings":["Mayo Clinic, Rochester, MN, USA"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108120874","display_name":"Ognjen Gaji\u0107","orcid":null},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ognjen Gajic","raw_affiliation_strings":["Mayo Clinic, Rochester, MN, USA"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5019313726"],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":1.9893,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.88230583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"7","issue":"3","first_page":"7287","last_page":"7294"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9685999751091003,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9685999751091003,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11195","display_name":"Simulation Techniques and Applications","score":0.9453999996185303,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psychological-intervention","display_name":"Psychological intervention","score":0.6636269688606262},{"id":"https://openalex.org/keywords/critically-ill","display_name":"Critically ill","score":0.5752949118614197},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5646979808807373},{"id":"https://openalex.org/keywords/harm","display_name":"Harm","score":0.4945954978466034},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.4934779405593872},{"id":"https://openalex.org/keywords/clinical-decision-support-system","display_name":"Clinical decision support system","score":0.4837510585784912},{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.4584074318408966},{"id":"https://openalex.org/keywords/virtual-patient","display_name":"Virtual patient","score":0.44559621810913086},{"id":"https://openalex.org/keywords/medical-emergency","display_name":"Medical emergency","score":0.36153316497802734},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.34616780281066895},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.29587405920028687},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.21656474471092224},{"id":"https://openalex.org/keywords/nursing","display_name":"Nursing","score":0.17416146397590637},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16649532318115234}],"concepts":[{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.6636269688606262},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.5752949118614197},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5646979808807373},{"id":"https://openalex.org/C2777363581","wikidata":"https://www.wikidata.org/wiki/Q15098235","display_name":"Harm","level":2,"score":0.4945954978466034},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.4934779405593872},{"id":"https://openalex.org/C63527458","wikidata":"https://www.wikidata.org/wiki/Q5133829","display_name":"Clinical decision support system","level":3,"score":0.4837510585784912},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.4584074318408966},{"id":"https://openalex.org/C2778533338","wikidata":"https://www.wikidata.org/wiki/Q7935148","display_name":"Virtual patient","level":2,"score":0.44559621810913086},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.36153316497802734},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34616780281066895},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.29587405920028687},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.21656474471092224},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.17416146397590637},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16649532318115234},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/lra.2022.3183253","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lra.2022.3183253","pdf_url":null,"source":{"id":"https://openalex.org/S4210169774","display_name":"IEEE Robotics and Automation Letters","issn_l":"2377-3766","issn":["2377-3766"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Robotics and Automation Letters","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7400000095367432,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G3885908740","display_name":null,"funder_award_id":"IIS-2123848","funder_id":"https://openalex.org/F4320335353","funder_display_name":"National Science Foundation of Sri Lanka"}],"funders":[{"id":"https://openalex.org/F4320335353","display_name":"National Science Foundation of Sri Lanka","ror":"https://ror.org/010xaa060"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1568586930","https://openalex.org/W1971574914","https://openalex.org/W2045946146","https://openalex.org/W2124436671","https://openalex.org/W2130637270","https://openalex.org/W2160691650","https://openalex.org/W2161511352","https://openalex.org/W2165405120","https://openalex.org/W2261885804","https://openalex.org/W2280404143","https://openalex.org/W2784195458","https://openalex.org/W2786689981","https://openalex.org/W2789343869","https://openalex.org/W2891400669","https://openalex.org/W2896893468","https://openalex.org/W2910608433","https://openalex.org/W2914446816","https://openalex.org/W2941876953","https://openalex.org/W2945644530","https://openalex.org/W2954595068","https://openalex.org/W2964696298","https://openalex.org/W2975302727","https://openalex.org/W2980832087","https://openalex.org/W2987930349","https://openalex.org/W3024273243","https://openalex.org/W3092002364","https://openalex.org/W3102833601","https://openalex.org/W3174468581","https://openalex.org/W4220902343","https://openalex.org/W6777206567"],"related_works":["https://openalex.org/W2046929026","https://openalex.org/W2779278343","https://openalex.org/W2533987749","https://openalex.org/W1996434451","https://openalex.org/W1569026615","https://openalex.org/W2791725133","https://openalex.org/W2112831187","https://openalex.org/W2122149485","https://openalex.org/W4232131108","https://openalex.org/W2128124510"],"abstract_inverted_index":{"The":[0],"COVID-19":[1],"pandemic":[2],"has":[3],"exposed":[4],"long":[5],"standing":[6],"deficiencies":[7],"in":[8,14,133,143],"critical":[9],"care":[10],"knowledge":[11],"and":[12,19,24,111,121,140,212,225],"practice":[13],"hospitals":[15],"worldwide.":[16],"New":[17],"methods":[18],"strategies":[20],"to":[21,34,42,49,58,75,155,163,178,219,222],"facilitate":[22],"timely":[23],"accurate":[25],"interventions":[26,184],"are":[27,152],"needed.":[28],"A":[29],"virtual":[30,68],"counterpart":[31],"(digital":[32],"twin)":[33],"critically":[35,92,169],"ill":[36,93,170],"patients":[37,171],"would":[38],"allow":[39],"bedside":[40,215],"providers":[41],"visualize":[43],"how":[44],"the":[45,56,60,88,96,100,109,165,180,193],"organ":[46,115],"systems":[47],"interact":[48],"cause":[50],"a":[51,63,67,83,134,144,157,173,196,214],"clinical":[52,89,104,119],"effect,":[53],"offering":[54],"them":[55,132,142],"opportunity":[57],"evaluate":[59],"effect":[61],"of":[62,91,102,168,182],"specific":[64],"intervention":[65],"on":[66,185],"patient":[69,74,186],"before":[70],"exposing":[71],"an":[72,206],"actual":[73],"potential":[76],"harm.":[77],"This":[78,188],"work":[79],"aims":[80],"at":[81],"developing":[82],"digital":[84,198],"simulation":[85,158,189],"that":[86,160],"models":[87],"pathway":[90],"patients.":[94],"Using":[95],"mixed-methods":[97],"approach":[98],"with":[99],"support":[101,217],"multiprofessional":[103],"experts,":[105],"we":[106],"first":[107],"identify":[108],"causal":[110],"associative":[112],"relationships":[113,126],"between":[114],"systems,":[116],"medical":[117,210],"conditions,":[118],"markers,":[120],"interventions.":[122],"We":[123],"record":[124],"these":[125],"as":[127,205,213],"structured":[128,149],"expert":[129,150],"rules,":[130],"depict":[131],"directed":[135],"acyclic":[136],"graph":[137,145],"(DAG)":[138],"format,":[139],"store":[141],"database":[146],"(Neo4j).":[147],"These":[148],"rules":[151],"subsequently":[153],"utilized":[154],"drive":[156],"application":[159],"enables":[161],"users":[162],"simulate":[164],"state":[166],"trajectory":[167],"over":[172],"given":[174],"simulated":[175],"time":[176],"period":[177],"test":[179],"impact":[181],"different":[183],"outcomes.":[187],"model":[190],"will":[191,202],"be":[192,203],"engine":[194],"driving":[195],"future":[197],"twin":[199],"prototype,":[200],"which":[201],"used":[204],"educational":[207],"tool":[208,218],"for":[209],"students,":[211],"decision":[216],"enable":[220],"clinicians":[221],"make":[223],"faster":[224],"more":[226],"informed":[227],"treatment":[228],"decisions.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}