{"id":"https://openalex.org/W3022952264","doi":"https://doi.org/10.1109/lifetech48969.2020.1570618909","title":"Estimating the Binding and Unbinding Rate of Motor Protein from Mitochondrial Motion","display_name":"Estimating the Binding and Unbinding Rate of Motor Protein from Mitochondrial Motion","publication_year":2020,"publication_date":"2020-03-01","ids":{"openalex":"https://openalex.org/W3022952264","doi":"https://doi.org/10.1109/lifetech48969.2020.1570618909","mag":"3022952264"},"language":"en","primary_location":{"id":"doi:10.1109/lifetech48969.2020.1570618909","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lifetech48969.2020.1570618909","pdf_url":null,"source":{"id":"https://openalex.org/S4306498653","display_name":"2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091763903","display_name":"Xu\u2010Dong Chen","orcid":"https://orcid.org/0000-0002-0152-5410"},"institutions":[{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xudong Chen","raw_affiliation_strings":["School of Electronic Science and Engineering, Nanjing University, Nanjing, China"],"affiliations":[{"raw_affiliation_string":"School of Electronic Science and Engineering, Nanjing University, Nanjing, China","institution_ids":["https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351500","display_name":"Ming Li","orcid":"https://orcid.org/0000-0003-1396-0767"},"institutions":[{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Li","raw_affiliation_strings":["School of Electronic Science and Engineering, Nanjing University, Nanjing, China"],"affiliations":[{"raw_affiliation_string":"School of Electronic Science and Engineering, Nanjing University, Nanjing, China","institution_ids":["https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100461271","display_name":"Tong Chen","orcid":"https://orcid.org/0000-0002-2456-7170"},"institutions":[{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tong Chen","raw_affiliation_strings":["School of Electronic Science and Engineering, Nanjing University, Nanjing, China"],"affiliations":[{"raw_affiliation_string":"School of Electronic Science and Engineering, Nanjing University, Nanjing, China","institution_ids":["https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016539834","display_name":"Sidan Du","orcid":"https://orcid.org/0000-0002-9966-3765"},"institutions":[{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sidan Du","raw_affiliation_strings":["School of Electronic Science and Engineering, Nanjing University, Nanjing, China"],"affiliations":[{"raw_affiliation_string":"School of Electronic Science and Engineering, Nanjing University, Nanjing, China","institution_ids":["https://openalex.org/I881766915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100421418","display_name":"Yang Li","orcid":"https://orcid.org/0000-0002-0736-251X"},"institutions":[{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Li","raw_affiliation_strings":["School of Electronic Science and Engineering, Nanjing University, Nanjing, China"],"affiliations":[{"raw_affiliation_string":"School of Electronic Science and Engineering, Nanjing University, Nanjing, China","institution_ids":["https://openalex.org/I881766915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5091763903"],"corresponding_institution_ids":["https://openalex.org/I881766915"],"apc_list":null,"apc_paid":null,"fwci":0.6026,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.60754717,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"109","issue":null,"first_page":"226","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.97079998254776,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hidden-markov-model","display_name":"Hidden Markov model","score":0.6683923602104187},{"id":"https://openalex.org/keywords/motion","display_name":"Motion (physics)","score":0.5209437608718872},{"id":"https://openalex.org/keywords/statistic","display_name":"Statistic","score":0.5032462477684021},{"id":"https://openalex.org/keywords/tracking","display_name":"Tracking (education)","score":0.4807819724082947},{"id":"https://openalex.org/keywords/markov-process","display_name":"Markov process","score":0.478431761264801},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.47182995080947876},{"id":"https://openalex.org/keywords/mitochondrion","display_name":"Mitochondrion","score":0.4588504433631897},{"id":"https://openalex.org/keywords/motion-estimation","display_name":"Motion estimation","score":0.43691766262054443},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.42936205863952637},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3488296866416931},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.342809796333313},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.33978718519210815},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3266751170158386},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.27728450298309326},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.21279096603393555},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1408660113811493},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.11389759182929993}],"concepts":[{"id":"https://openalex.org/C23224414","wikidata":"https://www.wikidata.org/wiki/Q176769","display_name":"Hidden Markov model","level":2,"score":0.6683923602104187},{"id":"https://openalex.org/C104114177","wikidata":"https://www.wikidata.org/wiki/Q79782","display_name":"Motion (physics)","level":2,"score":0.5209437608718872},{"id":"https://openalex.org/C89128539","wikidata":"https://www.wikidata.org/wiki/Q1949963","display_name":"Statistic","level":2,"score":0.5032462477684021},{"id":"https://openalex.org/C2775936607","wikidata":"https://www.wikidata.org/wiki/Q466845","display_name":"Tracking (education)","level":2,"score":0.4807819724082947},{"id":"https://openalex.org/C159886148","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov process","level":2,"score":0.478431761264801},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.47182995080947876},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.4588504433631897},{"id":"https://openalex.org/C10161872","wikidata":"https://www.wikidata.org/wiki/Q557891","display_name":"Motion estimation","level":2,"score":0.43691766262054443},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.42936205863952637},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3488296866416931},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.342809796333313},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.33978718519210815},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3266751170158386},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27728450298309326},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.21279096603393555},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1408660113811493},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.11389759182929993},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/lifetech48969.2020.1570618909","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lifetech48969.2020.1570618909","pdf_url":null,"source":{"id":"https://openalex.org/S4306498653","display_name":"2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W131176016","https://openalex.org/W1984510450","https://openalex.org/W1992264711","https://openalex.org/W1996764498","https://openalex.org/W2009885573","https://openalex.org/W2010179451","https://openalex.org/W2017267148","https://openalex.org/W2031280902","https://openalex.org/W2041625018","https://openalex.org/W2046353863","https://openalex.org/W2047460306","https://openalex.org/W2052939877","https://openalex.org/W2055572268","https://openalex.org/W2066179635","https://openalex.org/W2070319450","https://openalex.org/W2070376310","https://openalex.org/W2074935554","https://openalex.org/W2078056153","https://openalex.org/W2083971828","https://openalex.org/W2100664594","https://openalex.org/W2119818636","https://openalex.org/W2132379826","https://openalex.org/W2136425673","https://openalex.org/W2136937485","https://openalex.org/W2139861422","https://openalex.org/W2148819754","https://openalex.org/W2149090315","https://openalex.org/W2152913938","https://openalex.org/W2163859059","https://openalex.org/W2168187778","https://openalex.org/W2171029615","https://openalex.org/W3023299584","https://openalex.org/W4297810568"],"related_works":["https://openalex.org/W2053269318","https://openalex.org/W2364370872","https://openalex.org/W2025614924","https://openalex.org/W2294335174","https://openalex.org/W2097963413","https://openalex.org/W3145575561","https://openalex.org/W2001275470","https://openalex.org/W2073996508","https://openalex.org/W1591475660","https://openalex.org/W2164162849"],"abstract_inverted_index":{"Axonal":[0],"transport":[1],"plays":[2],"an":[3],"important":[4],"role":[5],"in":[6,18],"neuronal":[7],"growth,":[8],"survival":[9],"and":[10,29,43,46,88],"function.":[11],"Automatic":[12],"parameters":[13],"estimation":[14,56],"of":[15,36,66,73],"mitochondrial":[16,31,38,67,82],"motion":[17,39],"a":[19,26],"large":[20],"quantity":[21],"remains":[22],"challenging.":[23],"We":[24],"propose":[25],"method":[27,34,61,76],"imaging":[28],"quantifying":[30],"movement.":[32],"The":[33,55,75],"consists":[35],"tracking":[37],"from":[40],"fluorescent":[41],"images":[42],"estimating":[44],"binding":[45,87],"unbinding":[47,89],"rate":[48],"based":[49,84],"on":[50,85],"HMM":[51],"(hidden":[52],"Markov":[53],"model).":[54],"considers":[57],"not":[58],"only":[59],"statistic":[60],"but":[62],"also":[63],"the":[64,71,81,86],"mechanism":[65],"transport,":[68],"which":[69],"indicates":[70],"environment":[72,83],"axons.":[74],"allowed":[77],"us":[78],"to":[79],"detect":[80],"rate.":[90]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}