{"id":"https://openalex.org/W3217704975","doi":"https://doi.org/10.1109/lcsys.2021.3129320","title":"Chaos and Its Degradation-Promoting-Based Control in an Antithetic Integral Feedback Circuit","display_name":"Chaos and Its Degradation-Promoting-Based Control in an Antithetic Integral Feedback Circuit","publication_year":2021,"publication_date":"2021-11-19","ids":{"openalex":"https://openalex.org/W3217704975","doi":"https://doi.org/10.1109/lcsys.2021.3129320","mag":"3217704975"},"language":"en","primary_location":{"id":"doi:10.1109/lcsys.2021.3129320","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lcsys.2021.3129320","pdf_url":null,"source":{"id":"https://openalex.org/S4306422535","display_name":"IEEE Control Systems Letters","issn_l":"2475-1456","issn":["2475-1456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Control Systems Letters","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://jyx.jyu.fi/bitstreams/ec5fc371-093e-498d-972a-87f7f57559c9/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028246156","display_name":"Armin M. Zand","orcid":"https://orcid.org/0000-0002-0791-6156"},"institutions":[{"id":"https://openalex.org/I133529467","display_name":"Sharif University of Technology","ror":"https://ror.org/024c2fq17","country_code":"IR","type":"education","lineage":["https://openalex.org/I133529467"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Armin M. Zand","raw_affiliation_strings":["Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran","institution_ids":["https://openalex.org/I133529467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003620596","display_name":"Mohammad Saleh Tavazoei","orcid":"https://orcid.org/0000-0002-5428-0816"},"institutions":[{"id":"https://openalex.org/I133529467","display_name":"Sharif University of Technology","ror":"https://ror.org/024c2fq17","country_code":"IR","type":"education","lineage":["https://openalex.org/I133529467"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Saleh Tavazoei","raw_affiliation_strings":["Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran","institution_ids":["https://openalex.org/I133529467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083808886","display_name":"\u041d. \u0412. \u041a\u0443\u0437\u043d\u0435\u0446\u043e\u0432","orcid":"https://orcid.org/0000-0002-6474-9657"},"institutions":[{"id":"https://openalex.org/I94722563","display_name":"University of Jyv\u00e4skyl\u00e4","ror":"https://ror.org/05n3dz165","country_code":"FI","type":"education","lineage":["https://openalex.org/I94722563"]},{"id":"https://openalex.org/I172901346","display_name":"St Petersburg University","ror":"https://ror.org/023znxa73","country_code":"RU","type":"education","lineage":["https://openalex.org/I172901346"]},{"id":"https://openalex.org/I4210142628","display_name":"Institute of Problems of Mechanical Engineering","ror":"https://ror.org/047pt5178","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210142628","https://openalex.org/I4210164537"]}],"countries":["FI","RU"],"is_corresponding":false,"raw_author_name":"Nikolay V. Kuznetsov","raw_affiliation_strings":["Faculty of Information Technology, University of Jyv\u00e4skyl\u00e4, Jyv\u00e4skyl\u00e4, Finland","Mathematics and Mechanics Faculty, St. Petersburg State University, St. Petersburg, Russia","Russian Academy of Sciences, Institute for Problems in Mechanical Engineering, St. Petersburg, Russia"],"affiliations":[{"raw_affiliation_string":"Faculty of Information Technology, University of Jyv\u00e4skyl\u00e4, Jyv\u00e4skyl\u00e4, Finland","institution_ids":["https://openalex.org/I94722563"]},{"raw_affiliation_string":"Mathematics and Mechanics Faculty, St. Petersburg State University, St. Petersburg, Russia","institution_ids":["https://openalex.org/I172901346"]},{"raw_affiliation_string":"Russian Academy of Sciences, Institute for Problems in Mechanical Engineering, St. Petersburg, Russia","institution_ids":["https://openalex.org/I4210142628"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5028246156"],"corresponding_institution_ids":["https://openalex.org/I133529467"],"apc_list":null,"apc_paid":null,"fwci":1.4279,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.82267442,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"6","issue":null,"first_page":"1622","last_page":"1627"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11187","display_name":"Nonlinear Dynamics and Pattern Formation","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1705","display_name":"Computer Networks and Communications"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.7693964242935181},{"id":"https://openalex.org/keywords/chaotic","display_name":"Chaotic","score":0.6319162249565125},{"id":"https://openalex.org/keywords/attractor","display_name":"Attractor","score":0.5805726647377014},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.577172577381134},{"id":"https://openalex.org/keywords/electronic-circuit","display_name":"Electronic circuit","score":0.4806193709373474},{"id":"https://openalex.org/keywords/controller","display_name":"Controller (irrigation)","score":0.46805423498153687},{"id":"https://openalex.org/keywords/bifurcation","display_name":"Bifurcation","score":0.4270648658275604},{"id":"https://openalex.org/keywords/aperiodic-graph","display_name":"Aperiodic graph","score":0.42580994963645935},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.3540393114089966},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.3454206883907318},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2901805341243744},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.26856231689453125},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16439011693000793},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.09201627969741821}],"concepts":[{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.7693964242935181},{"id":"https://openalex.org/C2777052490","wikidata":"https://www.wikidata.org/wiki/Q5072826","display_name":"Chaotic","level":2,"score":0.6319162249565125},{"id":"https://openalex.org/C164380108","wikidata":"https://www.wikidata.org/wiki/Q507187","display_name":"Attractor","level":2,"score":0.5805726647377014},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.577172577381134},{"id":"https://openalex.org/C134146338","wikidata":"https://www.wikidata.org/wiki/Q1815901","display_name":"Electronic circuit","level":2,"score":0.4806193709373474},{"id":"https://openalex.org/C203479927","wikidata":"https://www.wikidata.org/wiki/Q5165939","display_name":"Controller (irrigation)","level":2,"score":0.46805423498153687},{"id":"https://openalex.org/C2781349735","wikidata":"https://www.wikidata.org/wiki/Q4904824","display_name":"Bifurcation","level":3,"score":0.4270648658275604},{"id":"https://openalex.org/C104247578","wikidata":"https://www.wikidata.org/wiki/Q4779368","display_name":"Aperiodic graph","level":2,"score":0.42580994963645935},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.3540393114089966},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3454206883907318},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2901805341243744},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.26856231689453125},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16439011693000793},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.09201627969741821},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/lcsys.2021.3129320","is_oa":false,"landing_page_url":"https://doi.org/10.1109/lcsys.2021.3129320","pdf_url":null,"source":{"id":"https://openalex.org/S4306422535","display_name":"IEEE Control Systems Letters","issn_l":"2475-1456","issn":["2475-1456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Control Systems Letters","raw_type":"journal-article"},{"id":"pmh:oai:jyx.jyu.fi:123456789/78876","is_oa":true,"landing_page_url":"http://urn.fi/URN:NBN:fi:jyu-202112025874","pdf_url":"https://jyx.jyu.fi/bitstreams/ec5fc371-093e-498d-972a-87f7f57559c9/download","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"A1"}],"best_oa_location":{"id":"pmh:oai:jyx.jyu.fi:123456789/78876","is_oa":true,"landing_page_url":"http://urn.fi/URN:NBN:fi:jyu-202112025874","pdf_url":"https://jyx.jyu.fi/bitstreams/ec5fc371-093e-498d-972a-87f7f57559c9/download","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"A1"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land","score":0.7400000095367432}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3217704975.pdf","grobid_xml":"https://content.openalex.org/works/W3217704975.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W114979488","https://openalex.org/W1515224583","https://openalex.org/W2016767879","https://openalex.org/W2030945597","https://openalex.org/W2117056464","https://openalex.org/W2128605063","https://openalex.org/W2139882086","https://openalex.org/W2152254020","https://openalex.org/W2247294682","https://openalex.org/W2472786230","https://openalex.org/W2805635954","https://openalex.org/W2914037619","https://openalex.org/W2949593751","https://openalex.org/W2951169596","https://openalex.org/W2952738056","https://openalex.org/W2954255554","https://openalex.org/W2992478128","https://openalex.org/W3002645837","https://openalex.org/W3105737633","https://openalex.org/W3169086554","https://openalex.org/W4234402252","https://openalex.org/W4245296879","https://openalex.org/W4253712238","https://openalex.org/W6770467227"],"related_works":["https://openalex.org/W2379488025","https://openalex.org/W2318462079","https://openalex.org/W2585728124","https://openalex.org/W2169362996","https://openalex.org/W2340294931","https://openalex.org/W2565482338","https://openalex.org/W2082884906","https://openalex.org/W2377705019","https://openalex.org/W2001163940","https://openalex.org/W2384473241"],"abstract_inverted_index":{"This":[0],"letter":[1],"deals":[2],"with":[3,31,94],"a":[4,20,32,55,81,101,174],"novel":[5],"variant":[6],"of":[7,35,44,50,64,79,119,171,185],"antithetic":[8,88,162],"integral":[9],"feedback":[10],"controller":[11,57,83,124],"(AIFC)":[12],"motifs":[13],"which":[14],"can":[15,90,107,178],"feature":[16],"robust":[17],"perfect":[18],"adaptation,":[19],"pervasive":[21],"(desired)":[22],"ability":[23],"in":[24,46,146],"natural":[25],"(synthetic)":[26],"biomolecular":[27],"circuits,":[28],"when":[29,110],"coupled":[30],"wide":[33],"class":[34],"process":[36],"networks":[37],"to":[38,84,104,122,129,141],"be":[39,142],"regulated.":[40],"Using":[41],"the":[42,47,60,65,87,98,116,123,154,159,169,183],"separation":[43],"time-scales":[45],"proposed":[48],"kind":[49],"AIFC,":[51],"here":[52],"we":[53,75,157],"find":[54],"reduced-order":[56],"that":[58,86,168],"captures":[59],"governing":[61],"slow":[62],"part":[63],"original":[66],"solutions":[67],"under":[68],"suitable":[69],"assumptions.":[70],"Inspired":[71],"by":[72,138,173],"R\u00f6ssler":[73],"systems,":[74],"then":[76],"make":[77],"use":[78],"such":[80],"simpler":[82],"show":[85],"circuit":[89],"exhibit":[91],"chaotic":[92,105],"behaviors":[93],"strange":[95],"attractors,":[96],"where":[97],"bifurcation":[99],"from":[100],"homeostatic":[102],"state":[103],"orbits":[106],"happen,":[108],"e.g.,":[109],"considering":[111],"saturated":[112],"Hill-type":[113],"reactions":[114],"for":[115],"actuation.":[117],"Addition":[118],"degradation":[120,172],"terms":[121],"species,":[125],"whether":[126],"naturally":[127],"due":[128],"dilution":[130],"or":[131],"exogenously":[132],"using":[133],"protein":[134],"tags,":[135],"is":[136],"showcased":[137],"simulation":[139],"results":[140],"an":[143],"effective":[144],"solution":[145],"suppressing":[147],"deterministic":[148],"chaos":[149,180],"and":[150,166,181],"aperiodic":[151],"oscillations.":[152],"In":[153],"same":[155],"vein,":[156],"recapitulate":[158],"recently":[160],"introduced":[161],"rein":[163,175],"IFC":[164],"motif":[165],"confirm":[167],"promotion":[170],"mechanism":[176],"also":[177],"control":[179],"improve":[182],"stability":[184],"closed-loop":[186],"circuit.":[187]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}