{"id":"https://openalex.org/W2603309649","doi":"https://doi.org/10.1109/la-cci.2016.7885738","title":"A Digital Pathology application for whole-slide histopathology image analysis based on genetic algorithm and Convolutional Networks","display_name":"A Digital Pathology application for whole-slide histopathology image analysis based on genetic algorithm and Convolutional Networks","publication_year":2016,"publication_date":"2016-11-01","ids":{"openalex":"https://openalex.org/W2603309649","doi":"https://doi.org/10.1109/la-cci.2016.7885738","mag":"2603309649"},"language":"en","primary_location":{"id":"doi:10.1109/la-cci.2016.7885738","is_oa":false,"landing_page_url":"https://doi.org/10.1109/la-cci.2016.7885738","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE Latin American Conference on Computational Intelligence (LA-CCI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032516586","display_name":"Mateo Puerto","orcid":null},"institutions":[{"id":"https://openalex.org/I3129686679","display_name":"University of the Llanos","ror":"https://ror.org/042335e16","country_code":"CO","type":"education","lineage":["https://openalex.org/I3129686679"]}],"countries":["CO"],"is_corresponding":true,"raw_author_name":"Mateo Puerto","raw_affiliation_strings":["GITECX Research Group, University of Los Llanos"],"affiliations":[{"raw_affiliation_string":"GITECX Research Group, University of Los Llanos","institution_ids":["https://openalex.org/I3129686679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077149811","display_name":"Tania Vargas","orcid":"https://orcid.org/0000-0002-0729-7308"},"institutions":[{"id":"https://openalex.org/I3129686679","display_name":"University of the Llanos","ror":"https://ror.org/042335e16","country_code":"CO","type":"education","lineage":["https://openalex.org/I3129686679"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Tania Vargas","raw_affiliation_strings":["GITECX Research Group, University of Los Llanos"],"affiliations":[{"raw_affiliation_string":"GITECX Research Group, University of Los Llanos","institution_ids":["https://openalex.org/I3129686679"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072005501","display_name":"\u00c1ngel Cruz-Roa","orcid":"https://orcid.org/0000-0003-3389-8913"},"institutions":[{"id":"https://openalex.org/I3129686679","display_name":"University of the Llanos","ror":"https://ror.org/042335e16","country_code":"CO","type":"education","lineage":["https://openalex.org/I3129686679"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Angel Cruz-Roa","raw_affiliation_strings":["GITECX Research Group, University of Los Llanos"],"affiliations":[{"raw_affiliation_string":"GITECX Research Group, University of Los Llanos","institution_ids":["https://openalex.org/I3129686679"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5032516586"],"corresponding_institution_ids":["https://openalex.org/I3129686679"],"apc_list":null,"apc_paid":null,"fwci":0.4285,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.81114833,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9041","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9678999781608582,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/digital-pathology","display_name":"Digital pathology","score":0.8687793016433716},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7799947261810303},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.703055739402771},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6079930067062378},{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.5877076387405396},{"id":"https://openalex.org/keywords/usability","display_name":"Usability","score":0.5534732341766357},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5265472531318665},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.4623035490512848},{"id":"https://openalex.org/keywords/magnification","display_name":"Magnification","score":0.4410393238067627},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.43006622791290283},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.42783018946647644},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.42599207162857056},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.41759246587753296},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3524993062019348},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.34042888879776},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.304465651512146}],"concepts":[{"id":"https://openalex.org/C2777522853","wikidata":"https://www.wikidata.org/wiki/Q5276128","display_name":"Digital pathology","level":2,"score":0.8687793016433716},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7799947261810303},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.703055739402771},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6079930067062378},{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.5877076387405396},{"id":"https://openalex.org/C170130773","wikidata":"https://www.wikidata.org/wiki/Q216378","display_name":"Usability","level":2,"score":0.5534732341766357},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5265472531318665},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.4623035490512848},{"id":"https://openalex.org/C4144372","wikidata":"https://www.wikidata.org/wiki/Q675287","display_name":"Magnification","level":2,"score":0.4410393238067627},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.43006622791290283},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.42783018946647644},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.42599207162857056},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.41759246587753296},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3524993062019348},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34042888879776},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.304465651512146},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/la-cci.2016.7885738","is_oa":false,"landing_page_url":"https://doi.org/10.1109/la-cci.2016.7885738","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE Latin American Conference on Computational Intelligence (LA-CCI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W22040386","https://openalex.org/W155183334","https://openalex.org/W1101750244","https://openalex.org/W1965451568","https://openalex.org/W1966730383","https://openalex.org/W1975103383","https://openalex.org/W1997864537","https://openalex.org/W2008797112","https://openalex.org/W2023244209","https://openalex.org/W2026893473","https://openalex.org/W2032679776","https://openalex.org/W2040245343","https://openalex.org/W2051765910","https://openalex.org/W2062177968","https://openalex.org/W2080971197","https://openalex.org/W2103061399","https://openalex.org/W2103243046","https://openalex.org/W2111892567","https://openalex.org/W2112936761","https://openalex.org/W2122394460","https://openalex.org/W2132031490","https://openalex.org/W2151608510","https://openalex.org/W2152150600","https://openalex.org/W2315817934","https://openalex.org/W3140395577","https://openalex.org/W6600893292","https://openalex.org/W6606191898","https://openalex.org/W6682679816"],"related_works":["https://openalex.org/W2905433371","https://openalex.org/W2888392564","https://openalex.org/W4310278675","https://openalex.org/W4388422664","https://openalex.org/W4390569940","https://openalex.org/W4361193272","https://openalex.org/W3023714767","https://openalex.org/W4282934193","https://openalex.org/W3082372604","https://openalex.org/W3115735825"],"abstract_inverted_index":{"The":[0,126,145],"last":[1],"decade":[2],"Digital":[3],"Pathology":[4],"is":[5],"coming":[6],"as":[7],"a":[8,89,95,110,115,173],"relevant":[9],"and":[10,16,36,101,169],"promising":[11],"area":[12],"for":[13,31,44,79,99,107,154,160],"cancer":[14],"research":[15],"clinical":[17],"practice":[18],"thanks":[19,165],"to":[20,55],"two":[21],"main":[22],"trends,":[23],"1)":[24],"the":[25,38,57,138,151,177,182],"availability":[26],"of":[27,40,88,103,105,141,166,176],"whole":[28],"slide":[29,34],"scanners":[30],"complete":[32],"pathology":[33],"digitalization,":[35],"2)":[37],"development":[39],"several":[41],"computational":[42,77],"method":[43,92,153],"histopathology":[45],"image":[46],"analysis.":[47,81],"However,":[48],"there":[49],"are":[50],"very":[51],"few":[52],"works":[53,123],"addressed":[54],"analyze":[56],"whole-slide":[58],"digitized":[59],"images":[60],"(WSI)":[61],"because":[62],"their":[63],"large":[64],"resolution":[65],"(e.g.":[66],"80,000":[67,69],"\u00d7":[68],"pixels":[70],"at":[71],"40\u00d7":[72],"magnification)":[73],"resulting":[74],"in":[75,109,112,121,134,148,181],"huge":[76],"cost":[78],"automatic":[80],"This":[82],"paper":[83],"presents":[84],"an":[85],"application":[86,147],"design":[87],"meta-heuristic":[90],"optimization":[91],"based":[93],"on":[94],"genetic":[96],"algorithm":[97],"(GA)":[98],"exploration":[100],"exploitation":[102],"regions":[104,180],"interest":[106],"diagnosis":[108,161],"WSI":[111,155],"combination":[113],"with":[114],"Convolutional":[116],"Neural":[117],"Network":[118],"(CNN)":[119],"trained":[120],"previous":[122],"[10],":[124],"[11].":[125],"preliminary":[127],"results":[128],"show":[129],"that":[130],"presented":[131],"solution":[132],"scales":[133],"computing":[135],"time":[136],"given":[137],"initial":[139],"number":[140],"samples":[142],"(initial":[143],"population).":[144],"developed":[146],"Java":[149],"including":[150],"GA":[152],"analysis":[156],"could":[157],"be":[158],"used":[159],"support":[162],"by":[163],"pathologists":[164],"its":[167],"usability":[168],"visual":[170],"interpretability":[171],"through":[172],"probability":[174],"map":[175],"invasive":[178],"tumor":[179],"WSI.":[183]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}