{"id":"https://openalex.org/W2280655674","doi":"https://doi.org/10.1109/jstsp.2016.2601485","title":"Identifying Seizure Onset Zone From the Causal Connectivity Inferred Using Directed Information","display_name":"Identifying Seizure Onset Zone From the Causal Connectivity Inferred Using Directed Information","publication_year":2016,"publication_date":"2016-08-18","ids":{"openalex":"https://openalex.org/W2280655674","doi":"https://doi.org/10.1109/jstsp.2016.2601485","mag":"2280655674"},"language":"en","primary_location":{"id":"doi:10.1109/jstsp.2016.2601485","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jstsp.2016.2601485","pdf_url":null,"source":{"id":"https://openalex.org/S42167783","display_name":"IEEE Journal of Selected Topics in Signal Processing","issn_l":"1932-4553","issn":["1932-4553","1941-0484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Selected Topics in Signal Processing","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/1512.08309","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051279777","display_name":"Rakesh Malladi","orcid":"https://orcid.org/0000-0002-7569-5332"},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rakesh Malladi","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041924687","display_name":"Giridhar P. Kalamangalam","orcid":"https://orcid.org/0000-0002-0178-4332"},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giridhar Kalamangalam","raw_affiliation_strings":["Department of Neurology, University of Texas Health Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Texas Health Center, Houston, TX, USA","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040141277","display_name":"Nitin Tandon","orcid":"https://orcid.org/0000-0002-2752-2365"},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nitin Tandon","raw_affiliation_strings":["Department of Neurosurgery, University of Texas Health Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, University of Texas Health Center, Houston, TX, USA","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061405587","display_name":"Behnaam Aazhang","orcid":"https://orcid.org/0000-0001-9536-7734"},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Behnaam Aazhang","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA","institution_ids":["https://openalex.org/I74775410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":3.1766,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.91596506,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"10","issue":"7","first_page":"1267","last_page":"1283"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transfer-entropy","display_name":"Transfer entropy","score":0.7515046000480652},{"id":"https://openalex.org/keywords/estimator","display_name":"Estimator","score":0.7467463612556458},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6958990097045898},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5340268611907959},{"id":"https://openalex.org/keywords/granger-causality","display_name":"Granger causality","score":0.5105465650558472},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.456913560628891},{"id":"https://openalex.org/keywords/causal-structure","display_name":"Causal structure","score":0.411375492811203},{"id":"https://openalex.org/keywords/entropy","display_name":"Entropy (arrow of time)","score":0.41011476516723633},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3433021903038025},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3363502323627472},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3361603617668152},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3328220844268799},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.21263203024864197},{"id":"https://openalex.org/keywords/principle-of-maximum-entropy","display_name":"Principle of maximum entropy","score":0.20901837944984436},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.14014628529548645}],"concepts":[{"id":"https://openalex.org/C182049051","wikidata":"https://www.wikidata.org/wiki/Q17147155","display_name":"Transfer entropy","level":3,"score":0.7515046000480652},{"id":"https://openalex.org/C185429906","wikidata":"https://www.wikidata.org/wiki/Q1130160","display_name":"Estimator","level":2,"score":0.7467463612556458},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6958990097045898},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5340268611907959},{"id":"https://openalex.org/C129824826","wikidata":"https://www.wikidata.org/wiki/Q2630107","display_name":"Granger causality","level":2,"score":0.5105465650558472},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.456913560628891},{"id":"https://openalex.org/C163504300","wikidata":"https://www.wikidata.org/wiki/Q2364925","display_name":"Causal structure","level":2,"score":0.411375492811203},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.41011476516723633},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3433021903038025},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3363502323627472},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3361603617668152},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3328220844268799},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21263203024864197},{"id":"https://openalex.org/C9679016","wikidata":"https://www.wikidata.org/wiki/Q1417473","display_name":"Principle of maximum entropy","level":2,"score":0.20901837944984436},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.14014628529548645},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/jstsp.2016.2601485","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jstsp.2016.2601485","pdf_url":null,"source":{"id":"https://openalex.org/S42167783","display_name":"IEEE Journal of Selected Topics in Signal Processing","issn_l":"1932-4553","issn":["1932-4553","1941-0484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Selected Topics in Signal Processing","raw_type":"journal-article"},{"id":"pmh:oai:arXiv.org:1512.08309","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1512.08309","pdf_url":"https://arxiv.org/pdf/1512.08309","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:1512.08309","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1512.08309","pdf_url":"https://arxiv.org/pdf/1512.08309","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.44999998807907104,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W250076511","https://openalex.org/W632115384","https://openalex.org/W845985309","https://openalex.org/W1489262227","https://openalex.org/W1534448729","https://openalex.org/W1547648311","https://openalex.org/W1559439075","https://openalex.org/W1563800609","https://openalex.org/W1905316980","https://openalex.org/W1965392255","https://openalex.org/W1971827710","https://openalex.org/W1980934101","https://openalex.org/W1981626709","https://openalex.org/W1985832257","https://openalex.org/W1987387046","https://openalex.org/W1995713768","https://openalex.org/W1999409691","https://openalex.org/W2001123550","https://openalex.org/W2002356739","https://openalex.org/W2009579332","https://openalex.org/W2020233396","https://openalex.org/W2022001004","https://openalex.org/W2024886389","https://openalex.org/W2025366179","https://openalex.org/W2029343818","https://openalex.org/W2031799655","https://openalex.org/W2041782669","https://openalex.org/W2056095844","https://openalex.org/W2058203079","https://openalex.org/W2061023335","https://openalex.org/W2076396344","https://openalex.org/W2078204079","https://openalex.org/W2079059681","https://openalex.org/W2080398083","https://openalex.org/W2082484220","https://openalex.org/W2093507948","https://openalex.org/W2095324495","https://openalex.org/W2095734615","https://openalex.org/W2096409350","https://openalex.org/W2099111195","https://openalex.org/W2101460669","https://openalex.org/W2107974789","https://openalex.org/W2109582949","https://openalex.org/W2111095086","https://openalex.org/W2113762408","https://openalex.org/W2116031726","https://openalex.org/W2119130526","https://openalex.org/W2128565466","https://openalex.org/W2136783219","https://openalex.org/W2139881468","https://openalex.org/W2140911775","https://openalex.org/W2156939381","https://openalex.org/W2163288162","https://openalex.org/W2168614460","https://openalex.org/W2174375947","https://openalex.org/W2178225550","https://openalex.org/W2478708596","https://openalex.org/W2501856495","https://openalex.org/W2963675110","https://openalex.org/W3105581519","https://openalex.org/W3123545922","https://openalex.org/W3123899698","https://openalex.org/W4231318153","https://openalex.org/W4233159434","https://openalex.org/W4243863038","https://openalex.org/W4245651501","https://openalex.org/W4294656048","https://openalex.org/W4300048831","https://openalex.org/W4300414004","https://openalex.org/W4301622824","https://openalex.org/W4302617909","https://openalex.org/W4393219574","https://openalex.org/W6629237864","https://openalex.org/W6680992663","https://openalex.org/W6681130209","https://openalex.org/W6926437754"],"related_works":["https://openalex.org/W1989349725","https://openalex.org/W2945806310","https://openalex.org/W2884017454","https://openalex.org/W2050334647","https://openalex.org/W4285118845","https://openalex.org/W1966203994","https://openalex.org/W2150055352","https://openalex.org/W2356475741","https://openalex.org/W2075237332","https://openalex.org/W2029083536"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3],"developed":[4],"a":[5,8,45,60,112,115],"model-based":[6,113,130,142],"and":[7,28,55,114,131],"data-driven":[9,116,132,137],"estimator":[10],"for":[11,174],"directed":[12],"information":[13,41],"(DI)":[14],"to":[15,29,48,59,81,120],"infer":[16,49],"the":[17,31,66,98,124,129,141,149,154,166],"causal":[18,50,125,160],"connectivity":[19,51,87,126,161],"graph":[20],"between":[21,52,88],"electrocorticographic":[22],"(ECoG)":[23],"signals":[24],"recorded":[25],"from":[26,123],"brain":[27],"identify":[30,121],"seizure":[32],"onset":[33],"zone":[34],"(SOZ)":[35],"in":[36,91],"epileptic":[37,93],"patients.":[38],"DI,":[39],"an":[40],"theoretic":[42],"quantity,":[43],"is":[44,56,95,165],"general":[46],"metric":[47],"time":[53],"series":[54],"not":[57],"restricted":[58],"particular":[61],"class":[62],"of":[63],"models":[64],"unlike":[65],"popular":[67],"metrics":[68],"based":[69],"on":[70,106],"Granger":[71],"causality":[72],"or":[73],"transfer":[74],"entropy.":[75],"The":[76,136,159],"proposed":[77,99,111],"estimators":[78],"are":[79],"shown":[80],"be":[82],"almost":[83],"surely":[84],"convergent.":[85],"Causal":[86],"ECoG":[89],"electrodes":[90],"five":[92],"patients":[94],"inferred":[96],"using":[97,128],"DI":[100,133],"estimators,":[101,134],"after":[102],"validating":[103],"their":[104],"performance":[105],"simulated":[107],"data.":[108],"We":[109],"then":[110],"SOZ":[117,122,138,143],"identification":[118,139,144],"algorithm":[119,145],"inferre":[127],"respectively.":[135],"outperforms":[140],"when":[146],"benchmarked":[147],"against":[148],"visual":[150],"analysis":[151,162],"by":[152],"neurologist,":[153],"current":[155],"clinical":[156],"gold":[157],"standard.":[158],"presented":[163],"here":[164],"first":[167],"step":[168],"toward":[169],"developing":[170],"novel":[171],"nonsurgical":[172],"treatments":[173],"epilepsy.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":2}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}
