{"id":"https://openalex.org/W4405968085","doi":"https://doi.org/10.1109/jbhi.2024.3524867","title":"Closed-Loop Respiratory Intervention Enhances Sleep Ventilation and Oxygen Saturation in Healthy Participants With Rapid High-Altitude Exposure","display_name":"Closed-Loop Respiratory Intervention Enhances Sleep Ventilation and Oxygen Saturation in Healthy Participants With Rapid High-Altitude Exposure","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4405968085","doi":"https://doi.org/10.1109/jbhi.2024.3524867","pmid":"https://pubmed.ncbi.nlm.nih.gov/40030781"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2024.3524867","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2024.3524867","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yilin Yang","orcid":"https://orcid.org/0000-0002-8196-8173"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yilin Yang","raw_affiliation_strings":["Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-8196-8173","affiliations":[{"raw_affiliation_string":"Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Li","orcid":"https://orcid.org/0000-0002-2282-1710"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210112150","display_name":"Institute of Automation","ror":"https://ror.org/022c3hy66","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112150"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["State Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-2282-1710","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210112150","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019778692","display_name":"Hanyu Chen","orcid":"https://orcid.org/0009-0009-3110-9360"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanyu Chen","raw_affiliation_strings":["Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0009-0009-3110-9360","affiliations":[{"raw_affiliation_string":"Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100401909","display_name":"Xiaochen Wang","orcid":"https://orcid.org/0000-0001-8911-3690"},"institutions":[{"id":"https://openalex.org/I4210087349","display_name":"China Resources (China)","ror":"https://ror.org/0026yhs27","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210087349"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaochen Wang","raw_affiliation_strings":["BMC Medical Company Ltd., Beijing, China","BMC Medical Co., Ltd., Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BMC Medical Company Ltd., Beijing, China","institution_ids":["https://openalex.org/I4210087349"]},{"raw_affiliation_string":"BMC Medical Co., Ltd., Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017003750","display_name":"Linhong Ji","orcid":"https://orcid.org/0000-0003-4533-4285"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linhong Ji","raw_affiliation_strings":["Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-4533-4285","affiliations":[{"raw_affiliation_string":"Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741594","display_name":"Boda Zhou","orcid":"https://orcid.org/0000-0001-8207-7367"},"institutions":[{"id":"https://openalex.org/I4210153550","display_name":"Beijing Tsinghua Chang Gung Hospital","ror":"https://ror.org/050nfgr37","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153550"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Boda Zhou","raw_affiliation_strings":["Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China","School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0001-8207-7367","affiliations":[{"raw_affiliation_string":"Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I4210153550","https://openalex.org/I99065089"]},{"raw_affiliation_string":"School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210153550"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100424963","display_name":"Chong Li","orcid":"https://orcid.org/0000-0003-4340-7436"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chong Li","raw_affiliation_strings":["School of Clinical Medicine (BTCH), Tsinghua Medicine, Tsinghua University, Beijing, China","Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China","School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-4340-7436","affiliations":[{"raw_affiliation_string":"School of Clinical Medicine (BTCH), Tsinghua Medicine, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Lab of Intelligent and Bio-mimetic Machinery, Department of Mechanical Engineering, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":null,"apc_paid":null,"fwci":1.6049,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.78932551,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"29","issue":"5","first_page":"3687","last_page":"3697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11579","display_name":"Cardiovascular and Diving-Related Complications","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/effects-of-high-altitude-on-humans","display_name":"Effects of high altitude on humans","score":0.6190062761306763},{"id":"https://openalex.org/keywords/ventilation","display_name":"Ventilation (architecture)","score":0.5886577367782593},{"id":"https://openalex.org/keywords/respiratory-rate","display_name":"Respiratory rate","score":0.5859926342964172},{"id":"https://openalex.org/keywords/tidal-volume","display_name":"Tidal volume","score":0.534087598323822},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5175751447677612},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.5058998465538025},{"id":"https://openalex.org/keywords/sleep","display_name":"Sleep (system call)","score":0.47923925518989563},{"id":"https://openalex.org/keywords/respiratory-minute-volume","display_name":"Respiratory minute volume","score":0.4775018095970154},{"id":"https://openalex.org/keywords/exhalation","display_name":"Exhalation","score":0.4548450708389282},{"id":"https://openalex.org/keywords/respiratory-system","display_name":"Respiratory system","score":0.44916635751724243},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.43802890181541443},{"id":"https://openalex.org/keywords/positive-airway-pressure","display_name":"Positive airway pressure","score":0.42370277643203735},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"Continuous positive airway pressure","score":0.41868647933006287},{"id":"https://openalex.org/keywords/oxygen-saturation","display_name":"Oxygen saturation","score":0.4114006757736206},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"Obstructive sleep apnea","score":0.40778130292892456},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.24490350484848022},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.24415510892868042},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.21421045064926147},{"id":"https://openalex.org/keywords/oxygen","display_name":"Oxygen","score":0.16685324907302856},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.10418465733528137},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.08109280467033386}],"concepts":[{"id":"https://openalex.org/C8240015","wikidata":"https://www.wikidata.org/wiki/Q918226","display_name":"Effects of high altitude on humans","level":2,"score":0.6190062761306763},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5886577367782593},{"id":"https://openalex.org/C8213797","wikidata":"https://www.wikidata.org/wiki/Q754250","display_name":"Respiratory rate","level":4,"score":0.5859926342964172},{"id":"https://openalex.org/C2777257755","wikidata":"https://www.wikidata.org/wiki/Q3493813","display_name":"Tidal volume","level":3,"score":0.534087598323822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5175751447677612},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5058998465538025},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.47923925518989563},{"id":"https://openalex.org/C79959777","wikidata":"https://www.wikidata.org/wiki/Q754333","display_name":"Respiratory minute volume","level":3,"score":0.4775018095970154},{"id":"https://openalex.org/C43396882","wikidata":"https://www.wikidata.org/wiki/Q2197000","display_name":"Exhalation","level":2,"score":0.4548450708389282},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.44916635751724243},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.43802890181541443},{"id":"https://openalex.org/C2775867611","wikidata":"https://www.wikidata.org/wiki/Q1024207","display_name":"Positive airway pressure","level":3,"score":0.42370277643203735},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.41868647933006287},{"id":"https://openalex.org/C76538665","wikidata":"https://www.wikidata.org/wiki/Q6294669","display_name":"Oxygen saturation","level":3,"score":0.4114006757736206},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.40778130292892456},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24490350484848022},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.24415510892868042},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21421045064926147},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.16685324907302856},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.10418465733528137},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08109280467033386},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000089382","descriptor_name":"Oxygen Saturation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000089382","descriptor_name":"Oxygen Saturation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000089382","descriptor_name":"Oxygen Saturation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000531","descriptor_name":"Altitude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000531","descriptor_name":"Altitude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000531","descriptor_name":"Altitude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000532","descriptor_name":"Altitude Sickness","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D000532","descriptor_name":"Altitude Sickness","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D000532","descriptor_name":"Altitude Sickness","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2024.3524867","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2024.3524867","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:40030781","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40030781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4300000071525574,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"awards":[{"id":"https://openalex.org/G4917311397","display_name":null,"funder_award_id":"20230484288","funder_id":"https://openalex.org/F4320334978","funder_display_name":"Beijing Nova Program"}],"funders":[{"id":"https://openalex.org/F4320334978","display_name":"Beijing Nova Program","ror":"https://ror.org/034k14f91"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W187665295","https://openalex.org/W1531279644","https://openalex.org/W1809000764","https://openalex.org/W1856825239","https://openalex.org/W1978296737","https://openalex.org/W1993234082","https://openalex.org/W2003416886","https://openalex.org/W2004116308","https://openalex.org/W2017577928","https://openalex.org/W2022584457","https://openalex.org/W2024919601","https://openalex.org/W2026191693","https://openalex.org/W2026222028","https://openalex.org/W2037855611","https://openalex.org/W2040463739","https://openalex.org/W2057087470","https://openalex.org/W2065732442","https://openalex.org/W2080022935","https://openalex.org/W2107664674","https://openalex.org/W2110238752","https://openalex.org/W2113227332","https://openalex.org/W2130249957","https://openalex.org/W2135809352","https://openalex.org/W2136167986","https://openalex.org/W2141474912","https://openalex.org/W2144969857","https://openalex.org/W2166766206","https://openalex.org/W2169167592","https://openalex.org/W2173309548","https://openalex.org/W2173373226","https://openalex.org/W2233774635","https://openalex.org/W2291362072","https://openalex.org/W2294535923","https://openalex.org/W2322458195","https://openalex.org/W2441644746","https://openalex.org/W2473660555","https://openalex.org/W2560252946","https://openalex.org/W2584358852","https://openalex.org/W2742188149","https://openalex.org/W2751069763","https://openalex.org/W2770886369","https://openalex.org/W2791697938","https://openalex.org/W2794272841","https://openalex.org/W2912654414","https://openalex.org/W3015537361","https://openalex.org/W3083327820","https://openalex.org/W3135025442","https://openalex.org/W3157936821","https://openalex.org/W4225144558","https://openalex.org/W4321508254","https://openalex.org/W6640432717"],"related_works":["https://openalex.org/W3032736716","https://openalex.org/W1996447318","https://openalex.org/W2239550753","https://openalex.org/W1732138557","https://openalex.org/W2032936085","https://openalex.org/W2144328154","https://openalex.org/W2072898286","https://openalex.org/W2083596363","https://openalex.org/W2549160642","https://openalex.org/W2059403142"],"abstract_inverted_index":{"Individuals":[0],"who":[1],"rapidly":[2],"exposed":[3],"to":[4,27,62,70,143],"high-altitude":[5,246],"environments":[6],"are":[7,60,68],"at":[8,64,95,132],"risk":[9],"of":[10,92,101,135,227],"developing":[11],"acute":[12],"mountain":[13],"sickness,":[14],"which":[15,38,88],"can":[16],"inhibit":[17],"the":[18,90,99,116,123,225,228,234],"respiratory":[19,85,146,167],"center":[20],"or":[21],"cause":[22],"upper":[23],"airway":[24,51,150],"obstruction,":[25],"leading":[26],"sleep":[28,42,171,176,216,219,243],"apnea":[29,209,244],"(SA).":[30],"SA":[31],"reduces":[32],"oxygen":[33],"saturation":[34],"(SPO2)":[35],"during":[36,126],"sleep,":[37],"not":[39],"only":[40],"impairs":[41],"quality":[43,177],"but":[44,57],"affects":[45],"cognitive":[46],"and":[47,67,118,154,170,175,211,218],"memory":[48],"function.":[49],"Positive":[50],"pressure":[52,104,120,151],"ventilation":[53,86,190],"helps":[54],"alleviate":[55],"SA,":[56],"existing":[58],"devices":[59],"prone":[61],"failure":[63,94],"high":[65,96],"altitudes":[66,97],"unable":[69],"realize":[71],"real-time":[72],"intervention":[73],"based":[74,121],"on":[75,122,157,204],"user's":[76,124],"physiological":[77],"parameters.":[78],"In":[79],"this":[80],"paper,":[81],"we":[82,108],"propose":[83],"a":[84,111,238],"system":[87],"addresses":[89],"issue":[91],"equipment":[93],"through":[98],"implementation":[100],"an":[102,133,186,195,212],"atmospheric":[103],"compensation":[105],"algorithm.":[106],"Additionally,":[107],"have":[109],"developed":[110],"closed-loop":[112,145,229],"algorithm":[113,230],"that":[114,183,224],"adjusts":[115],"inhalation":[117],"exhalation":[119],"SPO2":[125,199],"sleep.":[127],"Experimental":[128,180],"evaluations":[129],"were":[130,140,173],"conducted":[131],"altitude":[134],"3650":[136],"m,":[137],"where":[138],"participants":[139,184],"randomly":[141],"assigned":[142],"receive":[144],"intervention,":[147],"bi-level":[148],"positive":[149],"(Bi-PAP)":[152],"ventilation,":[153],"sham":[155],"stimulation":[156],"three":[158,205],"days.":[159],"Heart":[160],"rate":[161,168],"(HR),":[162],"SPO2,":[163],"tidal":[164],"volume":[165],"(VT),":[166],"(Rf)":[169],"papameters":[172],"collected,":[174],"was":[178],"assessed.":[179],"results":[181],"showed":[182],"experienced":[185],"26.3%":[187],"elevate":[188],"in":[189,198,208,214,245],"(p=0.004,":[191],"0.002,":[192],"0.003,":[193],"respectively),":[194],"8%":[196],"increase":[197],"(p":[200],"$<":[201],"$":[202],"0.001":[203],"days),":[206],"reduction":[207],"events":[210],"enhancement":[213],"deep":[215],"duration":[217],"stability.":[220],"These":[221],"findings":[222],"demonstrate":[223],"incorporation":[226],"has":[231],"significantly":[232],"enhanced":[233],"system's":[235],"effectiveness,":[236],"offering":[237],"novel":[239],"solution":[240],"for":[241],"addressing":[242],"environments.":[247]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}