{"id":"https://openalex.org/W4400315071","doi":"https://doi.org/10.1109/jbhi.2024.3423019","title":"Insula-Medial Prefrontal Cortex Functional Connectivity Modulated by Transcutaneous Auricular Vagus Nerve Stimulation: An fMRI Study","display_name":"Insula-Medial Prefrontal Cortex Functional Connectivity Modulated by Transcutaneous Auricular Vagus Nerve Stimulation: An fMRI Study","publication_year":2024,"publication_date":"2024-07-04","ids":{"openalex":"https://openalex.org/W4400315071","doi":"https://doi.org/10.1109/jbhi.2024.3423019","pmid":"https://pubmed.ncbi.nlm.nih.gov/38963749"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2024.3423019","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2024.3423019","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111365445","display_name":"Yujiao Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yujiao Zhang","raw_affiliation_strings":["Key Laboratory of Child Development and Learning Science, Ministry of Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China"],"raw_orcid":"https://orcid.org/0009-0007-8050-6042","affiliations":[{"raw_affiliation_string":"Key Laboratory of Child Development and Learning Science, Ministry of Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100689959","display_name":"Pan Lin","orcid":"https://orcid.org/0000-0001-7473-905X"},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pan Lin","raw_affiliation_strings":["Center for Mind & Brain Sciences and Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0001-7473-905X","affiliations":[{"raw_affiliation_string":"Center for Mind & Brain Sciences and Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, China","institution_ids":["https://openalex.org/I173759888"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111365457","display_name":"Ruimin Wang","orcid":"https://orcid.org/0000-0002-1133-2698"},"institutions":[{"id":"https://openalex.org/I177136067","display_name":"Saga University","ror":"https://ror.org/04f4wg107","country_code":"JP","type":"education","lineage":["https://openalex.org/I177136067"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ruimin Wang","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Faculty of Science and Engineering, Saga University, Saga, Japan"],"raw_orcid":"https://orcid.org/0000-0002-1133-2698","affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Faculty of Science and Engineering, Saga University, Saga, Japan","institution_ids":["https://openalex.org/I177136067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064911097","display_name":"Jiang Zhou","orcid":"https://orcid.org/0000-0003-1038-387X"},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiang Zhou","raw_affiliation_strings":["Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078886767","display_name":"Xiao\u2010Quan Xu","orcid":"https://orcid.org/0000-0001-5493-5256"},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoquan Xu","raw_affiliation_strings":["Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020220606","display_name":"Wenhao Jiang","orcid":"https://orcid.org/0000-0001-9169-3487"},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenhao Jiang","raw_affiliation_strings":["Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092566000","display_name":"Xiong\u2010Ying Pu","orcid":"https://orcid.org/0009-0007-7166-4030"},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiongying Pu","raw_affiliation_strings":["Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826","https://openalex.org/I4210152119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065049427","display_name":"Sheng Ge","orcid":"https://orcid.org/0000-0001-6152-1318"},"institutions":[{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sheng Ge","raw_affiliation_strings":["Key Laboratory of Child Development and Learning Science, Ministry of Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0001-6152-1318","affiliations":[{"raw_affiliation_string":"Key Laboratory of Child Development and Learning Science, Ministry of Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China","institution_ids":["https://openalex.org/I76569877"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6545,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.93308388,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"28","issue":"10","first_page":"5962","last_page":"5970"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vagus-nerve-stimulation","display_name":"Vagus nerve stimulation","score":0.8011807203292847},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6674610376358032},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"Prefrontal cortex","score":0.6635228991508484},{"id":"https://openalex.org/keywords/insula","display_name":"Insula","score":0.5706557035446167},{"id":"https://openalex.org/keywords/vagus-nerve","display_name":"Vagus nerve","score":0.5302481651306152},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.5187864303588867},{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"Deep brain stimulation","score":0.4735502302646637},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.4522762894630432},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4449392259120941},{"id":"https://openalex.org/keywords/cortex","display_name":"Cortex (anatomy)","score":0.43481796979904175},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.4261839985847473},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3335034251213074},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.07975426316261292},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.06962442398071289}],"concepts":[{"id":"https://openalex.org/C2780087125","wikidata":"https://www.wikidata.org/wiki/Q2062293","display_name":"Vagus nerve stimulation","level":4,"score":0.8011807203292847},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6674610376358032},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.6635228991508484},{"id":"https://openalex.org/C104996578","wikidata":"https://www.wikidata.org/wiki/Q827617","display_name":"Insula","level":2,"score":0.5706557035446167},{"id":"https://openalex.org/C2781404750","wikidata":"https://www.wikidata.org/wiki/Q190140","display_name":"Vagus nerve","level":3,"score":0.5302481651306152},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5187864303588867},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.4735502302646637},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.4522762894630432},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4449392259120941},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.43481796979904175},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.4261839985847473},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3335034251213074},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.07975426316261292},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.06962442398071289},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000087623","descriptor_name":"Insular Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004561","descriptor_name":"Transcutaneous Electric Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055536","descriptor_name":"Vagus Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055536","descriptor_name":"Vagus Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055536","descriptor_name":"Vagus Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055536","descriptor_name":"Vagus Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055536","descriptor_name":"Vagus Nerve Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2024.3423019","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2024.3423019","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:38963749","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38963749","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4579472307","display_name":null,"funder_award_id":"2242023k30022","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G7014189227","display_name":null,"funder_award_id":"62271141","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8734624840","display_name":"\u57fa\u4e8e\u591a\u6a21\u6001\u6838\u78c1\u5171\u632f\u6210\u50cf\u6280\u672f\u7684\u989d\u53f6\uff0d\u7eb9\u72b6\u4f53\u8ba4\u77e5\u63a7\u5236\u5927\u8111\u5de5\u4f5c\u673a\u5236\u7814\u7a76","funder_award_id":"62071177","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W1598274867","https://openalex.org/W1983183519","https://openalex.org/W1984796586","https://openalex.org/W1984871167","https://openalex.org/W1987599891","https://openalex.org/W1988343218","https://openalex.org/W1990134753","https://openalex.org/W2000575380","https://openalex.org/W2009494091","https://openalex.org/W2014704049","https://openalex.org/W2017887406","https://openalex.org/W2023808115","https://openalex.org/W2050618347","https://openalex.org/W2050973921","https://openalex.org/W2053258270","https://openalex.org/W2055027221","https://openalex.org/W2055942912","https://openalex.org/W2064445431","https://openalex.org/W2066208486","https://openalex.org/W2066396738","https://openalex.org/W2087755851","https://openalex.org/W2091340414","https://openalex.org/W2094533610","https://openalex.org/W2095350455","https://openalex.org/W2100582026","https://openalex.org/W2102121277","https://openalex.org/W2103654040","https://openalex.org/W2110065044","https://openalex.org/W2116658855","https://openalex.org/W2121478186","https://openalex.org/W2129028793","https://openalex.org/W2129624700","https://openalex.org/W2141015584","https://openalex.org/W2144351977","https://openalex.org/W2144427015","https://openalex.org/W2163973447","https://openalex.org/W2168088150","https://openalex.org/W2254545602","https://openalex.org/W2475049644","https://openalex.org/W2528109306","https://openalex.org/W2530226740","https://openalex.org/W2531418941","https://openalex.org/W2595720156","https://openalex.org/W2602583719","https://openalex.org/W2766962312","https://openalex.org/W2769026572","https://openalex.org/W2779532603","https://openalex.org/W2805229772","https://openalex.org/W2907341743","https://openalex.org/W2950180172","https://openalex.org/W2952903119","https://openalex.org/W2966254614","https://openalex.org/W2969944507","https://openalex.org/W2975198608","https://openalex.org/W2990150699","https://openalex.org/W3003628688","https://openalex.org/W3006109198","https://openalex.org/W3013419568","https://openalex.org/W3041018587","https://openalex.org/W3060956048","https://openalex.org/W3080971128","https://openalex.org/W3083909200","https://openalex.org/W3116371286","https://openalex.org/W3116829887","https://openalex.org/W3129406656","https://openalex.org/W3155335235","https://openalex.org/W3157149916","https://openalex.org/W3185178437","https://openalex.org/W3186047960","https://openalex.org/W3193876530","https://openalex.org/W3204675924","https://openalex.org/W3206254875","https://openalex.org/W4200145046","https://openalex.org/W4200460660","https://openalex.org/W4220735996","https://openalex.org/W4224061345","https://openalex.org/W4224994945","https://openalex.org/W4247236552","https://openalex.org/W4283763518","https://openalex.org/W4284889011","https://openalex.org/W4285707174","https://openalex.org/W4292167789","https://openalex.org/W4295269025","https://openalex.org/W4306670546","https://openalex.org/W4316039147","https://openalex.org/W4361285787","https://openalex.org/W4377140674","https://openalex.org/W4383342967","https://openalex.org/W4385064633","https://openalex.org/W4387297157","https://openalex.org/W4390115356","https://openalex.org/W4393950167","https://openalex.org/W4394851020"],"related_works":["https://openalex.org/W4301396970","https://openalex.org/W2006689666","https://openalex.org/W2550683708","https://openalex.org/W3146991102","https://openalex.org/W3010486731","https://openalex.org/W2899224757","https://openalex.org/W2015202629","https://openalex.org/W2094219890","https://openalex.org/W2013954586","https://openalex.org/W4280569028"],"abstract_inverted_index":{"Transcutaneous":[0],"auricular":[1],"vagus":[2],"nerve":[3],"stimulation":[4],"(taVNS)":[5],"is":[6,32,51],"an":[7],"emerging":[8],"neuromodulation":[9,108],"technology":[10],"that":[11,39,138,183],"has":[12,36],"been":[13,37],"reported":[14],"to":[15,54,189],"be":[16],"beneficial":[17],"in":[18,84,133,158,218],"the":[19,46,66,73,91,99,107,116,142,145,159,187,199,202,214],"treatment":[20],"of":[21,30,48,76,110,119,127,216],"diseases":[22],"by":[23,197],"several":[24],"studies,":[25],"but":[26],"its":[27],"exact":[28],"mechanism":[29,215],"action":[31],"still":[33],"unclear.":[34],"It":[35],"demonstrated":[38],"taVNS":[40,184,217],"can":[41],"influence":[42],"interoceptive":[43,49,85,103,192],"signals.":[44],"Notably,":[45],"processing":[47,105],"signals":[50],"directly":[52],"related":[53],"many":[55],"diseases,":[56],"such":[57],"as":[58],"depression,":[59],"anxiety,":[60],"and":[61,65,79,93,106,129,144,177,194,204],"insomnia.":[62],"The":[63,206],"insula":[64,92,143,203],"medial":[67],"prefrontal":[68],"cortex":[69],"(MPFC)":[70],"communicate":[71],"during":[72],"bottom-up":[74],"transmission":[75],"taVNS-induced":[77],"signals,":[78],"both":[80],"play":[81],"a":[82],"role":[83],"signal":[86,104],"processing.":[87],"By":[88],"focusing":[89],"on":[90],"MPFC,":[94],"our":[95,180],"research":[96],"pioneers":[97],"detail":[98],"potential":[100,165],"interactions":[101],"between":[102,141,201],"effects":[109,208],"taVNS,":[111,151],"providing":[112],"novel":[113],"insights":[114],"into":[115],"neurobiological":[117],"mechanisms":[118,166],"taVNS.":[120],"Two":[121],"functional":[122],"connectivity":[123,140],"(FC)":[124],"analyses":[125],"(region":[126],"interest-based":[128],"seed-based)":[130],"were":[131,154],"used":[132],"this":[134],"study.":[135],"We":[136],"observed":[137],"negative":[139],"MPFC":[146],"was":[147],"significantly":[148],"weakened":[149],"following":[150],"while":[152],"there":[153],"no":[155],"statistical":[156],"changes":[157],"sham":[160],"group.":[161],"Our":[162],"findings":[163],"elucidate":[164],"linking":[167],"vagal":[168],"activity":[169],"with":[170],"intrinsic":[171],"FC":[172,200],"among":[173],"specific":[174],"brain":[175],"regions":[176],"networks.":[178],"Specifically,":[179],"results":[181],"indicate":[182],"may":[185,209],"enhance":[186],"ability":[188],"flexibly":[190],"balance":[191],"awareness":[193],"cognitive":[195],"experiences":[196],"modulating":[198],"MPFC.":[205],"modulation":[207],"impact":[210],"body-brain":[211],"interactions,":[212],"suggesting":[213],"therapeutic":[219],"applications.":[220]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}