{"id":"https://openalex.org/W4313157423","doi":"https://doi.org/10.1109/jbhi.2022.3228603","title":"Multimodal Fusion Network for Detecting Hyperplastic Parathyroid Glands in SPECT/CT Images","display_name":"Multimodal Fusion Network for Detecting Hyperplastic Parathyroid Glands in SPECT/CT Images","publication_year":2022,"publication_date":"2022-12-12","ids":{"openalex":"https://openalex.org/W4313157423","doi":"https://doi.org/10.1109/jbhi.2022.3228603","pmid":"https://pubmed.ncbi.nlm.nih.gov/37015701"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2022.3228603","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2022.3228603","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027393873","display_name":"Meidi Chen","orcid":"https://orcid.org/0000-0002-6184-9820"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meidi Chen","raw_affiliation_strings":["School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-6184-9820","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047297167","display_name":"Zijin Chen","orcid":"https://orcid.org/0009-0000-4075-1499"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zijin Chen","raw_affiliation_strings":["Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I2801556517","https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034416132","display_name":"Yun Xi","orcid":"https://orcid.org/0000-0002-6002-523X"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Xi","raw_affiliation_strings":["Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I2801556517","https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039270843","display_name":"Xiaoya Qiao","orcid":"https://orcid.org/0000-0001-7226-4054"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoya Qiao","raw_affiliation_strings":["School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0001-7226-4054","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002902707","display_name":"Xiaonong Chen","orcid":"https://orcid.org/0000-0002-9092-2695"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaonong Chen","raw_affiliation_strings":["Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I2801556517","https://openalex.org/I183067930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073105215","display_name":"Qiu Huang","orcid":"https://orcid.org/0000-0002-2966-6450"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiu Huang","raw_affiliation_strings":["School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China","Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-2966-6450","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I2801556517","https://openalex.org/I183067930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5027393873"],"corresponding_institution_ids":["https://openalex.org/I183067930"],"apc_list":null,"apc_paid":null,"fwci":1.1275,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.7809211,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"27","issue":"3","first_page":"1524","last_page":"1534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11363","display_name":"Dental Radiography and Imaging","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11363","display_name":"Dental Radiography and Imaging","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6149681806564331},{"id":"https://openalex.org/keywords/modality","display_name":"Modality (human\u2013computer interaction)","score":0.610125720500946},{"id":"https://openalex.org/keywords/image-fusion","display_name":"Image fusion","score":0.5684474110603333},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5037395358085632},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4876224100589752},{"id":"https://openalex.org/keywords/single-photon-emission-computed-tomography","display_name":"Single-photon emission computed tomography","score":0.44429656863212585},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.438468873500824},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.39997369050979614},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.33488529920578003},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3254240155220032},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2939051687717438},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.10831955075263977}],"concepts":[{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6149681806564331},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.610125720500946},{"id":"https://openalex.org/C69744172","wikidata":"https://www.wikidata.org/wiki/Q860822","display_name":"Image fusion","level":3,"score":0.5684474110603333},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5037395358085632},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4876224100589752},{"id":"https://openalex.org/C2780441642","wikidata":"https://www.wikidata.org/wiki/Q849737","display_name":"Single-photon emission computed tomography","level":2,"score":0.44429656863212585},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.438468873500824},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.39997369050979614},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.33488529920578003},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3254240155220032},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2939051687717438},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.10831955075263977},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2022.3228603","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2022.3228603","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:37015701","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37015701","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W145469275","https://openalex.org/W169242661","https://openalex.org/W178047496","https://openalex.org/W639708223","https://openalex.org/W1536680647","https://openalex.org/W2028911404","https://openalex.org/W2063288762","https://openalex.org/W2136991956","https://openalex.org/W2261815052","https://openalex.org/W2405766151","https://openalex.org/W2524399695","https://openalex.org/W2531409750","https://openalex.org/W2565639579","https://openalex.org/W2626997132","https://openalex.org/W2805544462","https://openalex.org/W2883546801","https://openalex.org/W2884584803","https://openalex.org/W2884585870","https://openalex.org/W2895328943","https://openalex.org/W2902972155","https://openalex.org/W2911997543","https://openalex.org/W2973716406","https://openalex.org/W2979564444","https://openalex.org/W2979736498","https://openalex.org/W2980091915","https://openalex.org/W2991251333","https://openalex.org/W3019001223","https://openalex.org/W3046969780","https://openalex.org/W3083622693","https://openalex.org/W3093023437","https://openalex.org/W3106286734","https://openalex.org/W3106492384","https://openalex.org/W3125205865","https://openalex.org/W3130171175","https://openalex.org/W3136354976","https://openalex.org/W3136763234","https://openalex.org/W3154422954","https://openalex.org/W3199713133","https://openalex.org/W3201641086","https://openalex.org/W4211214771","https://openalex.org/W4225596864","https://openalex.org/W6692791147","https://openalex.org/W6756804208","https://openalex.org/W6801283239"],"related_works":["https://openalex.org/W2385859805","https://openalex.org/W2530972254","https://openalex.org/W4293226380","https://openalex.org/W2374013449","https://openalex.org/W73545470","https://openalex.org/W2364381299","https://openalex.org/W2374430585","https://openalex.org/W3144423903","https://openalex.org/W2377397762","https://openalex.org/W4313906399"],"abstract_inverted_index":{"In":[0,62],"secondary":[1],"hyperparathyroidism":[2],"(SHPT)":[3],"disease,":[4],"preoperatively":[5],"localizing":[6],"hyperplastic":[7,78],"parathyroid":[8,79,192],"glands":[9,17,47,53,80,149,178,193,206],"is":[10,54,122,185],"crucial":[11],"in":[12,48,81,146,194],"the":[13,22,89,108,112,117,164,167,177,186,202],"surgical":[14],"procedure.":[15],"These":[16],"can":[18],"be":[19],"detected":[20],"via":[21],"dual-modality":[23],"imaging":[24],"technique":[25],"single-photon":[26],"emission":[27],"computed":[28],"tomography/computed":[29],"tomography":[30],"(SPECT/CT)":[31],"since":[32],"it":[33],"has":[34],"high":[35],"sensitivity":[36,158],"and":[37,116,128],"provides":[38],"an":[39,156],"accurate":[40],"location.":[41],"However,":[42],"due":[43],"to":[44,57,76,124,189],"possible":[45],"low-uptake":[46,133,148],"SPECT":[49],"images,":[50,199],"manually":[51],"labeling":[52],"challenging,":[55],"not":[56],"mention":[58],"automatic":[59],"label":[60],"methods.":[61],"this":[63,184],"work,":[64],"we":[65],"present":[66],"a":[67,72,95],"deep":[68],"learning":[69],"method":[70,143],"with":[71,94,136,151,170],"novel":[73],"fusion":[74,86,104,142,153,173],"network":[75,87,92,174],"detect":[77,190],"SPECT/CT":[82,198],"images.":[83],"Our":[84,161],"proposed":[85,172],"follows":[88],"convolutional":[90],"neural":[91],"(CNN)":[93],"three-pathway":[96,168],"architecture":[97,169],"that":[98,140],"extracts":[99],"modality-specific":[100,118],"feature":[101,113],"maps.":[102],"The":[103],"network,":[105],"composed":[106],"of":[107,159,166,204],"channel":[109],"attention":[110,120],"module,":[111,115,121],"selection":[114],"spatial":[119],"designed":[123],"integrate":[125],"complementary":[126],"anatomical":[127],"functional":[129],"information,":[130],"especially":[131],"for":[132,175],"glands.":[134],"Experiments":[135],"patient":[137],"data":[138],"show":[139],"our":[141,171,182],"improves":[144],"performance":[145],"discerning":[147],"compared":[150],"current":[152],"strategies,":[154],"achieving":[155],"average":[157],"0.822.":[160],"results":[162],"prove":[163],"effectiveness":[165],"solving":[176],"detection":[179],"task.":[180],"To":[181],"knowledge,":[183],"first":[187],"study":[188],"abnormal":[191],"SHPT":[195],"disease":[196],"using":[197],"which":[200],"promotes":[201],"application":[203],"preoperative":[205],"localization.":[207]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}