{"id":"https://openalex.org/W3182889567","doi":"https://doi.org/10.1109/jbhi.2021.3095476","title":"Multimodal Disentangled Variational Autoencoder With Game Theoretic Interpretability for Glioma Grading","display_name":"Multimodal Disentangled Variational Autoencoder With Game Theoretic Interpretability for Glioma Grading","publication_year":2021,"publication_date":"2021-07-08","ids":{"openalex":"https://openalex.org/W3182889567","doi":"https://doi.org/10.1109/jbhi.2021.3095476","mag":"3182889567","pmid":"https://pubmed.ncbi.nlm.nih.gov/34236971"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2021.3095476","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2021.3095476","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045637179","display_name":"Jianhong Cheng","orcid":"https://orcid.org/0000-0001-6092-211X"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhong Cheng","raw_affiliation_strings":["Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","Institute of Guizhou Aerospace Measuring and Testing Technology, Guiyang, China"],"raw_orcid":"https://orcid.org/0000-0001-6092-211X","affiliations":[{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Institute of Guizhou Aerospace Measuring and Testing Technology, Guiyang, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101432685","display_name":"Min Gao","orcid":"https://orcid.org/0000-0001-6588-5936"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Gao","raw_affiliation_strings":["Department of Radiology Quality Control Center, Changsha, China","Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Quality Control Center, Changsha, China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I4210153856","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100642610","display_name":"Jin Liu","orcid":"https://orcid.org/0000-0002-4961-7074"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Liu","raw_affiliation_strings":["Department of Radiology Quality Control Center, Changsha, China","Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0002-4961-7074","affiliations":[{"raw_affiliation_string":"Department of Radiology Quality Control Center, Changsha, China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I4210153856","https://openalex.org/I139660479"]},{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031919173","display_name":"Hailin Yue","orcid":"https://orcid.org/0000-0002-3171-6445"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailin Yue","raw_affiliation_strings":["Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0002-3171-6445","affiliations":[{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005496603","display_name":"Hulin Kuang","orcid":"https://orcid.org/0000-0001-7341-9871"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hulin Kuang","raw_affiliation_strings":["Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0001-7341-9871","affiliations":[{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100361941","display_name":"Jun Liu","orcid":"https://orcid.org/0000-0002-7851-6782"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Liu","raw_affiliation_strings":["Department of Radiology Quality Control Center, Changsha, China","Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0002-7851-6782","affiliations":[{"raw_affiliation_string":"Department of Radiology Quality Control Center, Changsha, China","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China","institution_ids":["https://openalex.org/I4210153856","https://openalex.org/I139660479"]},{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100438360","display_name":"Jianxin Wang","orcid":"https://orcid.org/0000-0003-1516-0480"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Wang","raw_affiliation_strings":["Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China"],"raw_orcid":"https://orcid.org/0000-0003-1516-0480","affiliations":[{"raw_affiliation_string":"Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.4484,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.96613586,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"26","issue":"2","first_page":"673","last_page":"684"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.7641284465789795},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7148019075393677},{"id":"https://openalex.org/keywords/autoencoder","display_name":"Autoencoder","score":0.7108672857284546},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6844528913497925},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5196762681007385},{"id":"https://openalex.org/keywords/modalities","display_name":"Modalities","score":0.49422934651374817},{"id":"https://openalex.org/keywords/complementarity","display_name":"Complementarity (molecular biology)","score":0.47037166357040405},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4652370512485504},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.43651413917541504},{"id":"https://openalex.org/keywords/grading","display_name":"Grading (engineering)","score":0.423144668340683}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.7641284465789795},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7148019075393677},{"id":"https://openalex.org/C101738243","wikidata":"https://www.wikidata.org/wiki/Q786435","display_name":"Autoencoder","level":3,"score":0.7108672857284546},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6844528913497925},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5196762681007385},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.49422934651374817},{"id":"https://openalex.org/C202269582","wikidata":"https://www.wikidata.org/wiki/Q2644277","display_name":"Complementarity (molecular biology)","level":2,"score":0.47037166357040405},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4652370512485504},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.43651413917541504},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.423144668340683},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C147176958","wikidata":"https://www.wikidata.org/wiki/Q77590","display_name":"Civil engineering","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2021.3095476","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2021.3095476","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:34236971","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34236971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17","score":0.5}],"awards":[{"id":"https://openalex.org/G4066238608","display_name":null,"funder_award_id":"B18059","funder_id":"https://openalex.org/F4320327912","funder_display_name":"Higher Education Discipline Innovation Project"},{"id":"https://openalex.org/G423505088","display_name":null,"funder_award_id":"2019JJ50775","funder_id":"https://openalex.org/F4320322843","funder_display_name":"Natural Science Foundation of\u00a0Hunan Province"},{"id":"https://openalex.org/G4997333434","display_name":null,"funder_award_id":"61877059","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6199091500","display_name":null,"funder_award_id":"61802442","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322843","display_name":"Natural Science Foundation of\u00a0Hunan Province","ror":null},{"id":"https://openalex.org/F4320327912","display_name":"Higher Education Discipline Innovation Project","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W186912772","https://openalex.org/W1522301498","https://openalex.org/W1641498739","https://openalex.org/W1686810756","https://openalex.org/W1950489527","https://openalex.org/W1994406579","https://openalex.org/W2012231760","https://openalex.org/W2106235379","https://openalex.org/W2117060022","https://openalex.org/W2153444770","https://openalex.org/W2163352848","https://openalex.org/W2174661749","https://openalex.org/W2543050677","https://openalex.org/W2585666748","https://openalex.org/W2590458167","https://openalex.org/W2624516058","https://openalex.org/W2743924567","https://openalex.org/W2744130673","https://openalex.org/W2751069891","https://openalex.org/W2763355946","https://openalex.org/W2770261599","https://openalex.org/W2782414034","https://openalex.org/W2793691907","https://openalex.org/W2794055917","https://openalex.org/W2796433514","https://openalex.org/W2808184309","https://openalex.org/W2888749348","https://openalex.org/W2900530921","https://openalex.org/W2901381629","https://openalex.org/W2901906577","https://openalex.org/W2909533222","https://openalex.org/W2910109668","https://openalex.org/W2931870777","https://openalex.org/W2941818753","https://openalex.org/W2943960805","https://openalex.org/W2959170286","https://openalex.org/W2975798645","https://openalex.org/W2997339445","https://openalex.org/W3004935450","https://openalex.org/W3005711091","https://openalex.org/W3012174479","https://openalex.org/W3018852185","https://openalex.org/W3023317280","https://openalex.org/W3033039186","https://openalex.org/W3035399978","https://openalex.org/W3042519501","https://openalex.org/W3047472563","https://openalex.org/W3049320518","https://openalex.org/W3093725908","https://openalex.org/W3124559631","https://openalex.org/W3163024060","https://openalex.org/W6631190155","https://openalex.org/W6637373629","https://openalex.org/W6786593484","https://openalex.org/W7024228899"],"related_works":["https://openalex.org/W2905433371","https://openalex.org/W2888392564","https://openalex.org/W4310278675","https://openalex.org/W4388422664","https://openalex.org/W4390569940","https://openalex.org/W4361193272","https://openalex.org/W2963326959","https://openalex.org/W4388685194","https://openalex.org/W4312407344","https://openalex.org/W2894289927"],"abstract_inverted_index":{"Effective":[0],"fusion":[1,50],"of":[2,9,16,93,102,137,169],"multimodal":[3,64,79],"magnetic":[4],"resonance":[5],"imaging":[6,27],"(MRI)":[7],"is":[8,43,160],"great":[10],"significance":[11],"to":[12,20,31,40,115,133,150,162,173],"boost":[13],"the":[14,21,33,83,91,99,117,135,138,142,152,167,170,183],"accuracy":[15],"glioma":[17,70,153],"grading":[18,71],"thanks":[19],"complementary":[22,120],"information":[23,37,49],"provided":[24],"by":[25],"different":[26],"modalities.":[28,123],"However,":[29],"how":[30],"extract":[32],"common":[34,111,144],"and":[35,88,112,119,128,145,155,165,196,209,217],"distinctive":[36,113,146],"from":[38,77,90],"MRI":[39,80],"achieve":[41],"complementarity":[42],"still":[44],"an":[45],"open":[46],"problem":[47],"in":[48],"research.":[51],"In":[52],"this":[53],"study,":[54],"we":[55],"propose":[56],"a":[57,193,202],"deep":[58],"neural":[59],"network":[60],"model":[61,186],"termed":[62],"as":[63],"disentangled":[65,109,139,143],"variational":[66,103],"autoencoder":[67,104],"(MMD-VAE)":[68],"for":[69,95,105,222],"based":[72],"on":[73,177,192,201],"radiomics":[74,84],"features":[75,85,107,172],"extracted":[76,89],"preoperative":[78],"images.":[81],"Specifically,":[82],"are":[86,108,131,148],"quantized":[87],"region":[92],"interest":[94],"each":[96],"modality.":[97],"Then,":[98],"latent":[100],"representations":[101,114,147],"these":[106],"into":[110],"obtain":[116],"shared":[118],"data":[121],"among":[122],"Afterwards,":[124],"cross-modality":[125],"reconstruction":[126],"loss":[127,130],"common-distinctive":[129],"designed":[132],"ensure":[134],"effectiveness":[136],"representations.":[140],"Finally,":[141],"fused":[149],"predict":[151],"grades,":[154],"SHapley":[156],"Additive":[157],"exPlanations":[158],"(SHAP)":[159],"adopted":[161],"quantitatively":[163],"interpret":[164],"analyze":[166],"contribution":[168],"important":[171],"grading.":[174],"Experimental":[175],"results":[176,208],"two":[178],"benchmark":[179],"datasets":[180],"demonstrate":[181],"that":[182],"proposed":[184],"MMD-VAE":[185],"achieves":[187],"encouraging":[188],"predictive":[189],"performance":[190,199],"(AUC:0.9939)":[191],"public":[194],"dataset,":[195],"good":[197],"generalization":[198],"(AUC:0.9611)":[200],"cross-institutional":[203],"private":[204],"dataset.":[205],"These":[206],"quantitative":[207],"interpretations":[210],"may":[211],"help":[212],"radiologists":[213],"understand":[214],"gliomas":[215],"better":[216,219],"make":[218],"treatment":[220],"decisions":[221],"improving":[223],"clinical":[224],"outcomes.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":3}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}