{"id":"https://openalex.org/W3162598055","doi":"https://doi.org/10.1109/jbhi.2021.3080935","title":"A Controlled Thermoalgesic Stimulation Device for Exploring Novel Pain Perception Biomarkers","display_name":"A Controlled Thermoalgesic Stimulation Device for Exploring Novel Pain Perception Biomarkers","publication_year":2021,"publication_date":"2021-05-17","ids":{"openalex":"https://openalex.org/W3162598055","doi":"https://doi.org/10.1109/jbhi.2021.3080935","mag":"3162598055","pmid":"https://pubmed.ncbi.nlm.nih.gov/33999827"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2021.3080935","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2021.3080935","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.1109/JBHI.2021.3080935","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022969481","display_name":"Maider Nunez-Ibero","orcid":"https://orcid.org/0000-0002-6784-1715"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Maider Nunez-Ibero","raw_affiliation_strings":["Biomedical Research Doctorate Program, University of the Basque Country, Leioa, Spain"],"raw_orcid":"https://orcid.org/0000-0002-6784-1715","affiliations":[{"raw_affiliation_string":"Biomedical Research Doctorate Program, University of the Basque Country, Leioa, Spain","institution_ids":["https://openalex.org/I169108374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019484634","display_name":"Borja Camino\u2010Pontes","orcid":"https://orcid.org/0000-0002-9071-9304"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Borja Camino-Pontes","raw_affiliation_strings":["Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","Biomedical Research Doctorate Program, University of the Basque Country, Leioa, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9071-9304","affiliations":[{"raw_affiliation_string":"Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]},{"raw_affiliation_string":"Biomedical Research Doctorate Program, University of the Basque Country, Leioa, Spain","institution_ids":["https://openalex.org/I169108374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034263638","display_name":"Ibai D\u00edez","orcid":"https://orcid.org/0000-0001-5769-0178"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087356","display_name":"Gordon Center for Medical Imaging","ror":"https://ror.org/004y4rj95","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087356","https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ibai Diez","raw_affiliation_strings":["Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-5769-0178","affiliations":[{"raw_affiliation_string":"Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087356","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083291995","display_name":"Asier Erramuzpe","orcid":"https://orcid.org/0000-0002-9402-2184"},"institutions":[{"id":"https://openalex.org/I162361429","display_name":"Mondragon Unibertsitatea","ror":"https://ror.org/00wvqgd19","country_code":"ES","type":"education","lineage":["https://openalex.org/I162361429"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]}],"countries":["ES","IL"],"is_corresponding":false,"raw_author_name":"Asier Erramuzpe","raw_affiliation_strings":["Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","Biomedical Engineering Department, Faculty of Engineering, Mondragon University, Mondragon, Spain","Edmond & Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel"],"raw_orcid":"https://orcid.org/0000-0002-9402-2184","affiliations":[{"raw_affiliation_string":"Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]},{"raw_affiliation_string":"Biomedical Engineering Department, Faculty of Engineering, Mondragon University, Mondragon, Spain","institution_ids":["https://openalex.org/I162361429"]},{"raw_affiliation_string":"Edmond & Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073983455","display_name":"Endika Mart\u00ednez","orcid":"https://orcid.org/0000-0002-1755-2106"},"institutions":[{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210112283","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Bari","ror":"https://ror.org/022hq6c49","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210112283"]},{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["ES","IT"],"is_corresponding":false,"raw_author_name":"Endika Martinez-Gutierrez","raw_affiliation_strings":["Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","Dipartamento Interateneo di Fisica, Universita degli Studi di Bari Aldo Moro, and INFN, Sezione di Bari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-1755-2106","affiliations":[{"raw_affiliation_string":"Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]},{"raw_affiliation_string":"Dipartamento Interateneo di Fisica, Universita degli Studi di Bari Aldo Moro, and INFN, Sezione di Bari, Italy","institution_ids":["https://openalex.org/I4210112283","https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085541040","display_name":"Sebastiano Stramaglia","orcid":"https://orcid.org/0000-0002-5873-8564"},"institutions":[{"id":"https://openalex.org/I4210112283","display_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Bari","ror":"https://ror.org/022hq6c49","country_code":"IT","type":"facility","lineage":["https://openalex.org/I160013858","https://openalex.org/I4210112283"]},{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sebastiano Stramaglia","raw_affiliation_strings":["Dipartimento Interateneo di Fisica, Universita degli Studi di Bari Aldo Moro, and INFN, Sezione di Bari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-5873-8564","affiliations":[{"raw_affiliation_string":"Dipartimento Interateneo di Fisica, Universita degli Studi di Bari Aldo Moro, and INFN, Sezione di Bari, Italy","institution_ids":["https://openalex.org/I4210112283","https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061409284","display_name":"Javier Ortiz","orcid":"https://orcid.org/0000-0002-2459-5550"},"institutions":[{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier O. Alvarez-Cienfuegos","raw_affiliation_strings":["Department of Electronic Technology, University of the Basque Country, Bilbao, Spain"],"raw_orcid":"https://orcid.org/0000-0002-2459-5550","affiliations":[{"raw_affiliation_string":"Department of Electronic Technology, University of the Basque Country, Bilbao, Spain","institution_ids":["https://openalex.org/I169108374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065897233","display_name":"Jes\u00fas M. Cort\u00e9s","orcid":"https://orcid.org/0000-0002-9059-8194"},"institutions":[{"id":"https://openalex.org/I110594554","display_name":"Ikerbasque","ror":"https://ror.org/01cc3fy72","country_code":"ES","type":"other","lineage":["https://openalex.org/I110594554"]},{"id":"https://openalex.org/I169108374","display_name":"University of the Basque Country","ror":"https://ror.org/000xsnr85","country_code":"ES","type":"education","lineage":["https://openalex.org/I169108374"]},{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jesus M. Cortes","raw_affiliation_strings":["Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","Department of Cell Biology and Histology, University of the Basque Country, Leioa, Spain","IKERBASQUE: The Basque Foundation for Science, Bilbao, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9059-8194","affiliations":[{"raw_affiliation_string":"Biocruces-Bizkaia Health Research Institute, Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]},{"raw_affiliation_string":"Department of Cell Biology and Histology, University of the Basque Country, Leioa, Spain","institution_ids":["https://openalex.org/I169108374"]},{"raw_affiliation_string":"IKERBASQUE: The Basque Foundation for Science, Bilbao, Spain","institution_ids":["https://openalex.org/I110594554"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5022969481"],"corresponding_institution_ids":["https://openalex.org/I169108374"],"apc_list":null,"apc_paid":null,"fwci":0.4851,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.6223722,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"25","issue":"8","first_page":"2948","last_page":"2957"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.714900016784668,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.714900016784668,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12994","display_name":"Infrared Thermography in Medicine","score":0.07900000363588333,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10667","display_name":"Emotion and Mood Recognition","score":0.0649000033736229,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.8425230979919434},{"id":"https://openalex.org/keywords/fibromyalgia","display_name":"Fibromyalgia","score":0.6450172662734985},{"id":"https://openalex.org/keywords/photoplethysmogram","display_name":"Photoplethysmogram","score":0.5934905409812927},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.5650786757469177},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"Hemodynamics","score":0.4677306115627289},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.4585040211677551},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.44247886538505554},{"id":"https://openalex.org/keywords/nociception","display_name":"Nociception","score":0.4249945282936096},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3454105257987976},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.3447185158729553},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.34059250354766846},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.34029698371887207},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.31006383895874023},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.25398099422454834},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.17663192749023438},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.17639240622520447},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.09760233759880066}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.8425230979919434},{"id":"https://openalex.org/C2777831278","wikidata":"https://www.wikidata.org/wiki/Q540571","display_name":"Fibromyalgia","level":2,"score":0.6450172662734985},{"id":"https://openalex.org/C116390426","wikidata":"https://www.wikidata.org/wiki/Q7187885","display_name":"Photoplethysmogram","level":3,"score":0.5934905409812927},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5650786757469177},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.4677306115627289},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.4585040211677551},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44247886538505554},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.4249945282936096},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3454105257987976},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3447185158729553},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.34059250354766846},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.34029698371887207},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31006383895874023},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.25398099422454834},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.17663192749023438},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17639240622520447},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.09760233759880066},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017288","descriptor_name":"Pain Threshold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017288","descriptor_name":"Pain Threshold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017288","descriptor_name":"Pain Threshold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058748","descriptor_name":"Pain Perception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058748","descriptor_name":"Pain Perception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058748","descriptor_name":"Pain Perception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1109/jbhi.2021.3080935","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2021.3080935","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:33999827","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33999827","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null},{"id":"pmh:oai:dsp.tecnalia.com:11556/6355","is_oa":true,"landing_page_url":"https://doi.org/10.1109/JBHI.2021.3080935","pdf_url":null,"source":{"id":"https://openalex.org/S4306402037","display_name":"TECNALIA Publications (Fundaci\u00f3n TECNALIA Research & Innovation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210113430","host_organization_name":"Tecnalia","host_organization_lineage":["https://openalex.org/I4210113430"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:ebiltegia.mondragon.edu:20.500.11984/5599","is_oa":true,"landing_page_url":"https://katalogoa.mondragon.edu/janium-bin/janium_login_opac.pl?find&ficha_no=164638","pdf_url":null,"source":{"id":"https://openalex.org/S4377196532","display_name":"eRepository Mondragon University (Mondragon University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I162361429","host_organization_name":"Mondragon Unibertsitatea","host_organization_lineage":["https://openalex.org/I162361429"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics Vol. 25. N. 8. P.p. 2948-2957, 2021","raw_type":"info:eu-repo/semantics/submittedVersion"},{"id":"pmh:oai:ricerca.uniba.it:11586/378789","is_oa":false,"landing_page_url":"https://hdl.handle.net/11586/378789","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:dsp.tecnalia.com:11556/6355","is_oa":true,"landing_page_url":"https://doi.org/10.1109/JBHI.2021.3080935","pdf_url":null,"source":{"id":"https://openalex.org/S4306402037","display_name":"TECNALIA Publications (Fundaci\u00f3n TECNALIA Research & Innovation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210113430","host_organization_name":"Tecnalia","host_organization_lineage":["https://openalex.org/I4210113430"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.5699999928474426,"id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322262","display_name":"Ikerbasque, Basque Foundation for Science","ror":"https://ror.org/01cc3fy72"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W1540136440","https://openalex.org/W1587184621","https://openalex.org/W1862394037","https://openalex.org/W1981291046","https://openalex.org/W1982823463","https://openalex.org/W1997452544","https://openalex.org/W1998139571","https://openalex.org/W2001983596","https://openalex.org/W2006763945","https://openalex.org/W2010168206","https://openalex.org/W2010222850","https://openalex.org/W2010389802","https://openalex.org/W2022610999","https://openalex.org/W2033437894","https://openalex.org/W2048644905","https://openalex.org/W2059448132","https://openalex.org/W2059851411","https://openalex.org/W2062700118","https://openalex.org/W2080132175","https://openalex.org/W2091314241","https://openalex.org/W2093266575","https://openalex.org/W2096023955","https://openalex.org/W2096993177","https://openalex.org/W2108197576","https://openalex.org/W2112084158","https://openalex.org/W2114949906","https://openalex.org/W2115530814","https://openalex.org/W2139268737","https://openalex.org/W2144322310","https://openalex.org/W2145996826","https://openalex.org/W2153898363","https://openalex.org/W2155063410","https://openalex.org/W2161666777","https://openalex.org/W2165515236","https://openalex.org/W2266454428","https://openalex.org/W2272371184","https://openalex.org/W2338971691","https://openalex.org/W2488443118","https://openalex.org/W2491407016","https://openalex.org/W2536119267","https://openalex.org/W2564157307","https://openalex.org/W2580180620","https://openalex.org/W2588230266","https://openalex.org/W2588447348","https://openalex.org/W2609728307","https://openalex.org/W2610109047","https://openalex.org/W2752330802","https://openalex.org/W2759943737","https://openalex.org/W2782647253","https://openalex.org/W2790139232","https://openalex.org/W2898827376","https://openalex.org/W2900559304","https://openalex.org/W2903249182","https://openalex.org/W2904842854","https://openalex.org/W2906106440","https://openalex.org/W2909436996","https://openalex.org/W2910499539","https://openalex.org/W2917362868","https://openalex.org/W2921747393","https://openalex.org/W2931665018","https://openalex.org/W2973932066","https://openalex.org/W2977016586","https://openalex.org/W2981567370","https://openalex.org/W2982585903","https://openalex.org/W3000888090","https://openalex.org/W6722455756","https://openalex.org/W6736836267","https://openalex.org/W6760999836","https://openalex.org/W6767845875","https://openalex.org/W6769835177"],"related_works":["https://openalex.org/W2732360296","https://openalex.org/W1994871954","https://openalex.org/W4297152434","https://openalex.org/W2072858761","https://openalex.org/W1540261775","https://openalex.org/W4200107443","https://openalex.org/W4239033438","https://openalex.org/W1968279762","https://openalex.org/W4318970012","https://openalex.org/W2170552210"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"develop":[2],"a":[3,29,38,178,217],"new":[4],"device":[5,219],"for":[6,78,157,169,185,191],"identifying":[7],"physiological":[8],"markers":[9],"of":[10,114,127,151,181,208,224],"pain":[11,75,203,214],"perception":[12,215],"by":[13],"reading":[14],"the":[15,73,83,87,92,97,102,106,115,120,125,132,135,143,149,155,167,232],"brain's":[16],"electrical":[17],"activity":[18],"and":[19,47,134,145,187,197,220],"hemodynamic":[20],"interactions":[21,199],"while":[22,42,166],"applying":[23],"thermoalgesic":[24,128],"stimulation.":[25,129],"METHODS:":[26],"We":[27,70],"designed":[28],"compact":[30],"prototype":[31],"that":[32,86,230],"generates":[33],"well-controlled":[34],"thermal":[35,202,213],"stimuli":[36],"using":[37,216],"computer-driven":[39],"Peltier":[40,93],"cell":[41,94],"simultaneously":[43],"capturing":[44],"electroencephalography":[45],"(EEG)":[46],"photoplethysmography":[48],"(PPG)":[49],"signals.":[50],"The":[51,206],"study":[52,227],"was":[53,159],"performed":[54],"on":[55],"35":[56],"healthy":[57],"subjects":[58],"(mean":[59],"age":[60],"30.46":[61],"years,":[62],"SD":[63],"4.93":[64],"years;":[65],"20":[66],"males,":[67],"15":[68],"females).":[69],"first":[71],"determined":[72],"heat":[74],"threshold":[76],"(HPT)":[77],"each":[79],"subject,":[80],"defined":[81,101],"as":[82,105,237],"maximum":[84],"temperature":[85,110],"subject":[88],"can":[89,200],"withstand":[90],"when":[91],"gradually":[95],"increased":[96,171],"temperature.":[98],"Next,":[99],"we":[100],"painful":[103,243],"condition":[104,150],"one":[107],"occurring":[108],"at":[109],"equal":[111],"to":[112,119,226],"90%":[113],"HPT,":[116],"comparing":[117],"this":[118],"no-pain":[121],"state":[122],"(control)":[123],"in":[124,162,212],"absence":[126],"RESULTS:":[130],"Both":[131],"one-dimensional":[133],"two-dimensional":[136],"spectral":[137],"entropy":[138],"(SE)":[139],"obtained":[140],"from":[141],"both":[142],"EEG":[144,170,186],"PPG":[146,158],"signals":[147],"differentiated":[148],"pain.":[152],"In":[153],"particular,":[154],"SE":[156,168],"significantly":[160],"reduced":[161],"association":[163],"with":[164],"pain,":[165],"slightly.":[172],"Moreover,":[173],"significant":[174],"discrimination":[175],"occurred":[176],"within":[177],"specific":[179],"range":[180],"frequencies,":[182],"26-30":[183],"Hz":[184,190],"about":[188],"5-10":[189],"PPG.":[192],"CONCLUSION:":[193],"Hemodynamics,":[194],"brain":[195],"dynamics":[196],"their":[198],"discriminate":[201],"perception.":[204],"SIGNIFICANCE:":[205],"possibility":[207],"monitoring":[209],"on-line":[210],"variations":[211],"similar":[218],"algorithms":[221],"may":[222],"be":[223],"interest":[225],"different":[228],"pathologies":[229],"affect":[231],"peripheral":[233],"nervous":[234],"system,":[235],"such":[236],"small":[238],"fiber":[239],"neuropathies,":[240],"fibromyalgia":[241],"or":[242],"diabetic":[244],"neuropathy.":[245]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}