{"id":"https://openalex.org/W2998473000","doi":"https://doi.org/10.1109/jbhi.2019.2953978","title":"Towards Improving Skin Cancer Diagnosis by Integrating Microarray and RNA-Seq Datasets","display_name":"Towards Improving Skin Cancer Diagnosis by Integrating Microarray and RNA-Seq Datasets","publication_year":2019,"publication_date":"2019-12-23","ids":{"openalex":"https://openalex.org/W2998473000","doi":"https://doi.org/10.1109/jbhi.2019.2953978","mag":"2998473000","pmid":"https://pubmed.ncbi.nlm.nih.gov/31871000"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2019.2953978","is_oa":true,"landing_page_url":"https://doi.org/10.1109/jbhi.2019.2953978","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1109/jbhi.2019.2953978","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040100241","display_name":"Juan Manuel G\u00e1lvez","orcid":"https://orcid.org/0000-0003-2139-0565"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan M. Galvez","raw_affiliation_strings":["Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0003-2139-0565","affiliations":[{"raw_affiliation_string":"Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086984973","display_name":"Daniel Castillo-Secilla","orcid":"https://orcid.org/0000-0002-7380-1023"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Daniel Castillo-Secilla","raw_affiliation_strings":["Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0002-7380-1023","affiliations":[{"raw_affiliation_string":"Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059976520","display_name":"Luis Javier Herrera","orcid":"https://orcid.org/0000-0003-3220-9389"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Luis J. Herrera","raw_affiliation_strings":["Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0003-3220-9389","affiliations":[{"raw_affiliation_string":"Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058407177","display_name":"Olga Valenzuela","orcid":"https://orcid.org/0000-0001-6034-9392"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Olga Valenzuela","raw_affiliation_strings":["Department of Applied Mathematics, University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0001-6034-9392","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics, University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026264004","display_name":"Octavio Caba","orcid":"https://orcid.org/0000-0003-3426-8294"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Octavio Caba","raw_affiliation_strings":["Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0003-3426-8294","affiliations":[{"raw_affiliation_string":"Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089503870","display_name":"Jos\u00e9 Prados","orcid":"https://orcid.org/0000-0003-4303-7746"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jose C. Prados","raw_affiliation_strings":["Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0003-4303-7746","affiliations":[{"raw_affiliation_string":"Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047036875","display_name":"Francisco Ortu\u00f1o","orcid":"https://orcid.org/0000-0001-7424-1753"},"institutions":[{"id":"https://openalex.org/I4210086910","display_name":"Fundaci\u00f3n Progreso y Salud","ror":"https://ror.org/0048t7e91","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210086910","https://openalex.org/I4210152975","https://openalex.org/I918821925"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco M. Ortuno","raw_affiliation_strings":["Clinical Bioinformatics Area, Fundacion Progreso y Salud, Consejeria de Salud, Seville, Spain"],"raw_orcid":"https://orcid.org/0000-0001-7424-1753","affiliations":[{"raw_affiliation_string":"Clinical Bioinformatics Area, Fundacion Progreso y Salud, Consejeria de Salud, Seville, Spain","institution_ids":["https://openalex.org/I4210086910"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089029287","display_name":"Ignacio Rojas","orcid":"https://orcid.org/0000-0002-1033-5635"},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ignacio Rojas","raw_affiliation_strings":["Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain"],"raw_orcid":"https://orcid.org/0000-0002-1033-5635","affiliations":[{"raw_affiliation_string":"Department of Computer Architecture and Computer Technology, University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1968,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.7941631,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"24","issue":"7","first_page":"2119","last_page":"2130"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9904999732971191,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9904999732971191,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.9605000019073486,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.9585999846458435,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skin-cancer","display_name":"Skin cancer","score":0.6712716817855835},{"id":"https://openalex.org/keywords/multiclass-classification","display_name":"Multiclass classification","score":0.5879553556442261},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5568020343780518},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4835657775402069},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.47177743911743164},{"id":"https://openalex.org/keywords/pathological","display_name":"Pathological","score":0.4693148136138916},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.4455201029777527},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.4310108423233032},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3925524055957794},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24633270502090454},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.21672865748405457},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.19866317510604858},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13531139492988586}],"concepts":[{"id":"https://openalex.org/C2777789703","wikidata":"https://www.wikidata.org/wiki/Q192102","display_name":"Skin cancer","level":3,"score":0.6712716817855835},{"id":"https://openalex.org/C123860398","wikidata":"https://www.wikidata.org/wiki/Q6934605","display_name":"Multiclass classification","level":3,"score":0.5879553556442261},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5568020343780518},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4835657775402069},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47177743911743164},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4693148136138916},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4455201029777527},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4310108423233032},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3925524055957794},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24633270502090454},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.21672865748405457},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19866317510604858},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13531139492988586},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000081246","descriptor_name":"RNA-Seq","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/jbhi.2019.2953978","is_oa":true,"landing_page_url":"https://doi.org/10.1109/jbhi.2019.2953978","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:31871000","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31871000","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null},{"id":"pmh:oai:digibug.ugr.es:10481/96330","is_oa":true,"landing_page_url":"https://hdl.handle.net/10481/96330","pdf_url":"https://digibug.ugr.es/bitstream/10481/96330/1/Towards_Improving_Skin_Cancer_Diagnosis_by_Integrating_Microarray_and_RNA-Seq_Datasets.pdf","source":{"id":"https://openalex.org/S4306400567","display_name":"Institutional Repository of the University of Granada (University of Granada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I173304897","host_organization_name":"Universidad de Granada","host_organization_lineage":["https://openalex.org/I173304897"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal article"},{"id":"pmh:oai:www.repositoriosalud.es:10668/14873","is_oa":true,"landing_page_url":"http://hdl.handle.net/10668/14873","pdf_url":"https://ieeexplore.ieee.org/ielx7/6221020/9130988/08939388.pdf","source":{"id":"https://openalex.org/S4377196114","display_name":"RISalud Institutional Health Repository of Andaluc\u00eda","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"research article"}],"best_oa_location":{"id":"doi:10.1109/jbhi.2019.2953978","is_oa":true,"landing_page_url":"https://doi.org/10.1109/jbhi.2019.2953978","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4300000071525574,"id":"https://metadata.un.org/sdg/3"},{"display_name":"Peace, Justice and strong institutions","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W1490161904","https://openalex.org/W1529230314","https://openalex.org/W1559060276","https://openalex.org/W1577029325","https://openalex.org/W1964940342","https://openalex.org/W1973094248","https://openalex.org/W1981509058","https://openalex.org/W1981552604","https://openalex.org/W1986348806","https://openalex.org/W1986849266","https://openalex.org/W2003880562","https://openalex.org/W2008264512","https://openalex.org/W2010834438","https://openalex.org/W2014461750","https://openalex.org/W2021880506","https://openalex.org/W2024858956","https://openalex.org/W2026791237","https://openalex.org/W2037275986","https://openalex.org/W2052570068","https://openalex.org/W2054233335","https://openalex.org/W2063261057","https://openalex.org/W2063295519","https://openalex.org/W2072602203","https://openalex.org/W2093745661","https://openalex.org/W2096192437","https://openalex.org/W2098872693","https://openalex.org/W2100239923","https://openalex.org/W2102921564","https://openalex.org/W2106608030","https://openalex.org/W2107665951","https://openalex.org/W2108234281","https://openalex.org/W2108722802","https://openalex.org/W2109488005","https://openalex.org/W2110112697","https://openalex.org/W2116041602","https://openalex.org/W2116079122","https://openalex.org/W2116634113","https://openalex.org/W2120865735","https://openalex.org/W2127274965","https://openalex.org/W2131987814","https://openalex.org/W2134526812","https://openalex.org/W2141335157","https://openalex.org/W2146512944","https://openalex.org/W2148708580","https://openalex.org/W2149175829","https://openalex.org/W2152393933","https://openalex.org/W2154362705","https://openalex.org/W2154698608","https://openalex.org/W2155345760","https://openalex.org/W2158217645","https://openalex.org/W2159096710","https://openalex.org/W2170219300","https://openalex.org/W2170505850","https://openalex.org/W2170551349","https://openalex.org/W2183056077","https://openalex.org/W2237162482","https://openalex.org/W2284583894","https://openalex.org/W2289125335","https://openalex.org/W2400121309","https://openalex.org/W2407778364","https://openalex.org/W2418387125","https://openalex.org/W2461041754","https://openalex.org/W2497764970","https://openalex.org/W2573152477","https://openalex.org/W2573337666","https://openalex.org/W2603756957","https://openalex.org/W2616823333","https://openalex.org/W2620782833","https://openalex.org/W2767944948","https://openalex.org/W2769165274","https://openalex.org/W2769619799","https://openalex.org/W2778008284","https://openalex.org/W2790347080","https://openalex.org/W2791315675","https://openalex.org/W2795960027","https://openalex.org/W2800788706","https://openalex.org/W2800942801","https://openalex.org/W2801400022","https://openalex.org/W2810775565","https://openalex.org/W2885669402","https://openalex.org/W2890837645","https://openalex.org/W2896850685","https://openalex.org/W2911935466","https://openalex.org/W2915815599","https://openalex.org/W2939354219","https://openalex.org/W3104887532","https://openalex.org/W3191661929","https://openalex.org/W4244848121","https://openalex.org/W4250359879","https://openalex.org/W4292671544","https://openalex.org/W6633301734","https://openalex.org/W6651154441","https://openalex.org/W6748964210","https://openalex.org/W6761751852"],"related_works":["https://openalex.org/W2365243064","https://openalex.org/W3108298832","https://openalex.org/W2386699790","https://openalex.org/W2055939901","https://openalex.org/W2018724029","https://openalex.org/W4388992558","https://openalex.org/W2063918854","https://openalex.org/W2533581028","https://openalex.org/W2373252393","https://openalex.org/W3037187668"],"abstract_inverted_index":{"Many":[0],"clinical":[1,34],"studies":[2],"have":[3,115,208],"revealed":[4],"the":[5,20,100,120],"high":[6,209],"biological":[7,219],"similarities":[8,16],"existing":[9],"among":[10,214],"different":[11,69,222],"skin":[12,24,54,107,127,146,151,158,163,223],"pathological":[13,55,128,147,224],"states.":[14,164,225],"These":[15],"create":[17],"difficulties":[18],"in":[19,57,119],"efficient":[21,81],"diagnosis":[22,168],"of":[23,63,102,135,167,193],"cancer,":[25],"and":[26,30,80,160,186,195,216],"encourage":[27],"to":[28,72,84,116,144,203,221],"study":[29,131],"design":[31],"new":[32,104,111,170],"intelligent":[33],"decision":[35],"support":[36],"systems.":[37],"In":[38],"this":[39],"sense,":[40],"gene":[41,210],"expression":[42,211],"analysis":[43],"can":[44],"help":[45],"find":[46],"differentially":[47],"expressed":[48],"genes":[49],"(DEGs)":[50],"simultaneously":[51],"discerning":[52,142],"multiple":[53,64],"states":[56],"a":[58,91,133,153],"single":[59],"test.":[60],"The":[61],"integration":[62],"heterogeneous":[65],"transcriptomic":[66],"datasets":[67],"requires":[68],"pipeline":[70],"stages":[71],"be":[73,117],"properly":[74],"designed:":[75],"from":[76],"suitable":[77],"batch":[78],"merging":[79],"biomarker":[82],"selection":[83],"automated":[85],"classification":[86,178],"assessment.":[87],"This":[88],"article":[89],"presents":[90],"novel":[92],"approach":[93],"addressing":[94],"all":[95],"these":[96],"technical":[97],"issues,":[98],"with":[99],"intention":[101],"providing":[103],"sights":[105],"about":[106],"cancer":[108],"diagnosis.":[109],"Although":[110],"future":[112],"efforts":[113],"will":[114],"made":[118],"search":[121],"for":[122,141],"better":[123],"biomarkers":[124],"recognizing":[125],"specific":[126],"states,":[129],"our":[130],"found":[132],"panel":[134],"8":[136],"highly":[137],"relevant":[138],"multiclass":[139,188,205],"DEGs":[140,206],"up":[143],"10":[145],"states:":[148],"2":[149,155],"healthy":[150],"conditions":[152],"priori,":[154],"cataloged":[156],"precancerous":[157],"diseases":[159],"6":[161],"cancerous":[162],"Their":[165],"power":[166],"over":[169],"samples":[171],"was":[172],"widely":[173],"tested":[174],"by":[175],"previously":[176],"well-trained":[177],"models.":[179],"Robust":[180],"performance":[181],"metrics":[182],"such":[183],"as":[184],"overall":[185],"mean":[187],"F1-score":[189],"outperformed":[190],"recognition":[191],"rates":[192],"94%":[194],"80%,":[196],"respectively.":[197],"Clinicians":[198],"should":[199],"give":[200],"special":[201],"attention":[202],"highlighted":[204],"that":[207],"changes":[212],"present":[213],"them,":[215],"understand":[217],"their":[218],"relationship":[220]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}