{"id":"https://openalex.org/W2895554062","doi":"https://doi.org/10.1109/jbhi.2018.2874185","title":"Microsimulation Model Using Christiana Care Early Warning System (CEWS) to Evaluate Physiological Deterioration","display_name":"Microsimulation Model Using Christiana Care Early Warning System (CEWS) to Evaluate Physiological Deterioration","publication_year":2018,"publication_date":"2018-10-04","ids":{"openalex":"https://openalex.org/W2895554062","doi":"https://doi.org/10.1109/jbhi.2018.2874185","mag":"2895554062","pmid":"https://pubmed.ncbi.nlm.nih.gov/30295635"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2018.2874185","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2018.2874185","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100365187","display_name":"Bin Li","orcid":"https://orcid.org/0000-0002-5198-6311"},"institutions":[{"id":"https://openalex.org/I78715868","display_name":"University of Arkansas at Fayetteville","ror":"https://ror.org/05jbt9m15","country_code":"US","type":"education","lineage":["https://openalex.org/I78715868"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin Li","raw_affiliation_strings":["College of Engineering, University of Arkansas, Fayetteville, AR, USA"],"raw_orcid":"https://orcid.org/0000-0002-5198-6311","affiliations":[{"raw_affiliation_string":"College of Engineering, University of Arkansas, Fayetteville, AR, USA","institution_ids":["https://openalex.org/I78715868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052240317","display_name":"Shengfan Zhang","orcid":"https://orcid.org/0000-0001-9866-7177"},"institutions":[{"id":"https://openalex.org/I78715868","display_name":"University of Arkansas at Fayetteville","ror":"https://ror.org/05jbt9m15","country_code":"US","type":"education","lineage":["https://openalex.org/I78715868"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shengfan Zhang","raw_affiliation_strings":["College of Engineering, University of Arkansas, Fayetteville, AR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Engineering, University of Arkansas, Fayetteville, AR, USA","institution_ids":["https://openalex.org/I78715868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036400651","display_name":"Stephen Hoover","orcid":"https://orcid.org/0000-0002-3916-4577"},"institutions":[{"id":"https://openalex.org/I1281704429","display_name":"Christiana Care Health System","ror":"https://ror.org/02h905004","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281704429"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Hoover","raw_affiliation_strings":["Value Institute, Christiana Care Health System, Newark, DE, USA"],"raw_orcid":"https://orcid.org/0000-0002-3916-4577","affiliations":[{"raw_affiliation_string":"Value Institute, Christiana Care Health System, Newark, DE, USA","institution_ids":["https://openalex.org/I1281704429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112385471","display_name":"Ryan Arnold","orcid":null},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryan Arnold","raw_affiliation_strings":["Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013796744","display_name":"M\u00fcge Capan","orcid":"https://orcid.org/0000-0003-3194-6117"},"institutions":[{"id":"https://openalex.org/I4210133369","display_name":"Decision Sciences (United States)","ror":"https://ror.org/03gcvf773","country_code":"US","type":"company","lineage":["https://openalex.org/I4210133369"]},{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Muge Capan","raw_affiliation_strings":["Decision Sciences & MIS, Drexel University Bennett's LeBow College of Business, Philadelphia, PA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3194-6117","affiliations":[{"raw_affiliation_string":"Decision Sciences & MIS, Drexel University Bennett's LeBow College of Business, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309","https://openalex.org/I4210133369"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3255,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.63635738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"23","issue":"5","first_page":"2189","last_page":"2195"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.9581999778747559,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12246","display_name":"Chronic Disease Management Strategies","score":0.9555000066757202,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-warning-score","display_name":"Early warning score","score":0.8693090081214905},{"id":"https://openalex.org/keywords/psychological-intervention","display_name":"Psychological intervention","score":0.6649245619773865},{"id":"https://openalex.org/keywords/informatics","display_name":"Informatics","score":0.5928245186805725},{"id":"https://openalex.org/keywords/warning-system","display_name":"Warning system","score":0.5676571726799011},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.54847252368927},{"id":"https://openalex.org/keywords/health-informatics","display_name":"Health informatics","score":0.530483067035675},{"id":"https://openalex.org/keywords/rapid-response-team","display_name":"Rapid response team","score":0.4837524890899658},{"id":"https://openalex.org/keywords/demographics","display_name":"Demographics","score":0.4825277030467987},{"id":"https://openalex.org/keywords/microsimulation","display_name":"Microsimulation","score":0.44599252939224243},{"id":"https://openalex.org/keywords/medical-emergency","display_name":"Medical emergency","score":0.4433097541332245},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.42812809348106384},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4053126573562622},{"id":"https://openalex.org/keywords/actuarial-science","display_name":"Actuarial science","score":0.34223678708076477},{"id":"https://openalex.org/keywords/nursing","display_name":"Nursing","score":0.2214103639125824},{"id":"https://openalex.org/keywords/business","display_name":"Business","score":0.18096008896827698},{"id":"https://openalex.org/keywords/demography","display_name":"Demography","score":0.15409252047538757},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.12255859375},{"id":"https://openalex.org/keywords/public-health","display_name":"Public health","score":0.11771884560585022}],"concepts":[{"id":"https://openalex.org/C2777671062","wikidata":"https://www.wikidata.org/wiki/Q6889402","display_name":"Early warning score","level":2,"score":0.8693090081214905},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.6649245619773865},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.5928245186805725},{"id":"https://openalex.org/C29825287","wikidata":"https://www.wikidata.org/wiki/Q1427940","display_name":"Warning system","level":2,"score":0.5676571726799011},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.54847252368927},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.530483067035675},{"id":"https://openalex.org/C2910912111","wikidata":"https://www.wikidata.org/wiki/Q7294220","display_name":"Rapid response team","level":2,"score":0.4837524890899658},{"id":"https://openalex.org/C2780084366","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demographics","level":2,"score":0.4825277030467987},{"id":"https://openalex.org/C2780015235","wikidata":"https://www.wikidata.org/wiki/Q1934035","display_name":"Microsimulation","level":2,"score":0.44599252939224243},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.4433097541332245},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42812809348106384},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4053126573562622},{"id":"https://openalex.org/C162118730","wikidata":"https://www.wikidata.org/wiki/Q1128453","display_name":"Actuarial science","level":1,"score":0.34223678708076477},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2214103639125824},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.18096008896827698},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.15409252047538757},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.12255859375},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.11771884560585022},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C22212356","wikidata":"https://www.wikidata.org/wiki/Q775325","display_name":"Transport engineering","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000075902","descriptor_name":"Clinical Deterioration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000075902","descriptor_name":"Clinical Deterioration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000075902","descriptor_name":"Clinical Deterioration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000080162","descriptor_name":"Early Warning Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000080162","descriptor_name":"Early Warning Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000080162","descriptor_name":"Early Warning Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008991","descriptor_name":"Monitoring, Physiologic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008991","descriptor_name":"Monitoring, Physiologic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008991","descriptor_name":"Monitoring, Physiologic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2018.2874185","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2018.2874185","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:30295635","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30295635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"display_name":"Gender equality","id":"https://metadata.un.org/sdg/5"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1911849192","https://openalex.org/W1993827883","https://openalex.org/W2001324925","https://openalex.org/W2023957014","https://openalex.org/W2031777168","https://openalex.org/W2033668092","https://openalex.org/W2047944129","https://openalex.org/W2052324431","https://openalex.org/W2063985057","https://openalex.org/W2073455467","https://openalex.org/W2095056449","https://openalex.org/W2096083921","https://openalex.org/W2101199071","https://openalex.org/W2102399689","https://openalex.org/W2113633980","https://openalex.org/W2116600877","https://openalex.org/W2121103668","https://openalex.org/W2122080175","https://openalex.org/W2122693662","https://openalex.org/W2132400950","https://openalex.org/W2133677911","https://openalex.org/W2151256554","https://openalex.org/W2169901874","https://openalex.org/W2270416318","https://openalex.org/W2301550665","https://openalex.org/W2601918726","https://openalex.org/W2605955539","https://openalex.org/W4241894325","https://openalex.org/W4285719527","https://openalex.org/W6735651947"],"related_works":["https://openalex.org/W3126956915","https://openalex.org/W4318917545","https://openalex.org/W2137861465","https://openalex.org/W3212229609","https://openalex.org/W2888171411","https://openalex.org/W2397677514","https://openalex.org/W2914293784","https://openalex.org/W2407382301","https://openalex.org/W1495820741","https://openalex.org/W1807259383"],"abstract_inverted_index":{"While":[0],"physiological":[1,34,69],"warning":[2,70],"signs":[3,71],"prior":[4],"to":[5,66,82,122,134,160,164,202,237],"deterioration":[6,35,205],"events":[7],"during":[8],"hospitalization":[9],"have":[10],"been":[11],"widely":[12],"studied,":[13],"evaluating":[14,247],"clinical":[15,249],"interventions,":[16],"such":[17],"as":[18],"rapid":[19],"response":[20],"team":[21],"(RRT)":[22],"activations,":[23],"based":[24,87,212],"on":[25,88,126,154,168,213,216,244],"scoring":[26,39,59],"systems":[27,40],"remains":[28],"an":[29],"understudied":[30],"area.":[31],"Simulation":[32],"of":[33,78,101,144,185,193,224,226],"patterns":[36,206],"represented":[37],"by":[38,129],"can":[41],"facilitate":[42],"testing":[43],"different":[44],"RRT":[45,74,85,124,210],"policies":[46,86,125,165,211],"without":[47],"disturbing":[48],"care":[49,231],"processes.":[50],"Christiana":[51],"Care":[52],"Early":[53],"Warning":[54],"System":[55],"(CEWS)":[56],"is":[57,81,198],"a":[58,99,115,199,234],"system":[60],"developed":[61,114],"at":[62],"the":[63,68,141,174,182,188,222],"study":[64,80],"hospital":[65],"detect":[67],"and":[72,91,108,132,171,207,232,240,246],"inform":[73,238],"activations.":[75],"The":[76,195],"objective":[77],"this":[79],"evaluate":[83,209],"CEWS-triggered":[84],"patient":[89],"demographics":[90],"policy":[92],"structures.":[93],"Using":[94],"retrospective":[95],"data":[96],"derived":[97],"from":[98],"subset":[100],"electronic":[102],"health":[103,217,241],"records":[104],"between":[105],"December":[106,109],"2015":[107],"2016":[110],"(6000":[111],"patients),":[112],"we":[113],"microsimulation":[116],"model":[117,197],"with":[118],"integrated":[119],"regression":[120],"analysis":[121],"compare":[123],"subpopulations":[127],"defined":[128],"age,":[130],"gender,":[131],"comorbidities":[133],"find":[135],"score":[136,178],"thresholds":[137],"that":[138,152,166],"result":[139],"in":[140,173],"lowest":[142,183],"percent":[143],"time":[145,186],"spent":[146],"above":[147],"critical":[148,189],"CEWS":[149],"values.":[150],"Policies":[151],"rely":[153,167],"average":[155],"scores":[156],"were":[157],"more":[158],"sensitive":[159],"threshold":[161,179],"changes":[162],"compared":[163],"current":[169],"value":[170],"change":[172],"CEWS.":[175],"Policy":[176],"using":[177],"10":[180],"provided":[181],"percentage":[184],"under":[187],"condition":[190],"for":[191],"majority":[192],"subpopulations.":[194],"proposed":[196],"novel":[200],"framework":[201],"simulate":[203],"individual":[204],"systematically":[208],"their":[214],"impact":[215],"conditions.":[218],"Our":[219],"work":[220],"highlights":[221],"importance":[223],"integration":[225],"data-driven":[227],"models":[228],"into":[229],"personalized":[230],"represents":[233],"significant":[235],"opportunity":[236],"biomedical":[239],"informatics":[242],"research":[243],"designing":[245],"EWS-based":[248],"interventions.":[250]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}