{"id":"https://openalex.org/W2546948708","doi":"https://doi.org/10.1109/jbhi.2016.2623421","title":"Segmentation of White Blood Cells Image Using Adaptive Location and Iteration","display_name":"Segmentation of White Blood Cells Image Using Adaptive Location and Iteration","publication_year":2016,"publication_date":"2016-11-04","ids":{"openalex":"https://openalex.org/W2546948708","doi":"https://doi.org/10.1109/jbhi.2016.2623421","mag":"2546948708","pmid":"https://pubmed.ncbi.nlm.nih.gov/27834657"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2016.2623421","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2016.2623421","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100747879","display_name":"Yuehua Liu","orcid":"https://orcid.org/0000-0002-0312-6763"},"institutions":[{"id":"https://openalex.org/I55538621","display_name":"China Jiliang University","ror":"https://ror.org/05v1y0t93","country_code":"CN","type":"education","lineage":["https://openalex.org/I55538621"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yuehua Liu","raw_affiliation_strings":["College of Sciences, China Jiliang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"College of Sciences, China Jiliang University, Hangzhou, China","institution_ids":["https://openalex.org/I55538621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045211553","display_name":"Feilong Cao","orcid":"https://orcid.org/0000-0002-1690-5694"},"institutions":[{"id":"https://openalex.org/I55538621","display_name":"China Jiliang University","ror":"https://ror.org/05v1y0t93","country_code":"CN","type":"education","lineage":["https://openalex.org/I55538621"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feilong Cao","raw_affiliation_strings":["College of Sciences, China Jiliang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"College of Sciences, China Jiliang University, Hangzhou, China","institution_ids":["https://openalex.org/I55538621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090390841","display_name":"Jianwei Zhao","orcid":"https://orcid.org/0000-0001-9566-2178"},"institutions":[{"id":"https://openalex.org/I55538621","display_name":"China Jiliang University","ror":"https://ror.org/05v1y0t93","country_code":"CN","type":"education","lineage":["https://openalex.org/I55538621"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianwei Zhao","raw_affiliation_strings":["College of Sciences, China Jiliang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"College of Sciences, China Jiliang University, Hangzhou, China","institution_ids":["https://openalex.org/I55538621"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102209154","display_name":"Jianjun Chu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jianjun Chu","raw_affiliation_strings":["Jiashan Jasdaq Medical Device Corporation, Ltd., Jiashan, China"],"affiliations":[{"raw_affiliation_string":"Jiashan Jasdaq Medical Device Corporation, Ltd., Jiashan, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100747879"],"corresponding_institution_ids":["https://openalex.org/I55538621"],"apc_list":null,"apc_paid":null,"fwci":3.0501,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.94573759,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"21","issue":"6","first_page":"1644","last_page":"1655"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9684000015258789,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/initialization","display_name":"Initialization","score":0.8336957097053528},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.775421679019928},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7453717589378357},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7158552408218384},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.6577938795089722},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5677987337112427},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5218071937561035},{"id":"https://openalex.org/keywords/scale-space-segmentation","display_name":"Scale-space segmentation","score":0.44511258602142334}],"concepts":[{"id":"https://openalex.org/C114466953","wikidata":"https://www.wikidata.org/wiki/Q6034165","display_name":"Initialization","level":2,"score":0.8336957097053528},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.775421679019928},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7453717589378357},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7158552408218384},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.6577938795089722},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5677987337112427},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5218071937561035},{"id":"https://openalex.org/C65885262","wikidata":"https://www.wikidata.org/wiki/Q7429708","display_name":"Scale-space segmentation","level":4,"score":0.44511258602142334},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2016.2623421","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2016.2623421","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:27834657","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27834657","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8452094105","display_name":null,"funder_award_id":"61571410","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8846416659","display_name":null,"funder_award_id":"61672477","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1678695179","https://openalex.org/W1689909837","https://openalex.org/W1980276039","https://openalex.org/W1983626406","https://openalex.org/W1996326832","https://openalex.org/W2008700866","https://openalex.org/W2008840310","https://openalex.org/W2041878092","https://openalex.org/W2044562217","https://openalex.org/W2066624635","https://openalex.org/W2077915271","https://openalex.org/W2080860745","https://openalex.org/W2087699088","https://openalex.org/W2097459996","https://openalex.org/W2098663280","https://openalex.org/W2104095591","https://openalex.org/W2110158442","https://openalex.org/W2110218375","https://openalex.org/W2113201641","https://openalex.org/W2116046277","https://openalex.org/W2119391377","https://openalex.org/W2121927366","https://openalex.org/W2124351162","https://openalex.org/W2138398901","https://openalex.org/W2143516773","https://openalex.org/W2145023731","https://openalex.org/W2155687875","https://openalex.org/W2161969291","https://openalex.org/W2164507445","https://openalex.org/W2167171202","https://openalex.org/W2168356304","https://openalex.org/W2170796084","https://openalex.org/W2440598369","https://openalex.org/W2467617155","https://openalex.org/W2534457893","https://openalex.org/W2534622136","https://openalex.org/W4239147634","https://openalex.org/W6637264554","https://openalex.org/W6674715393"],"related_works":["https://openalex.org/W1986655823","https://openalex.org/W2185902295","https://openalex.org/W2103507220","https://openalex.org/W3144569342","https://openalex.org/W3011384228","https://openalex.org/W2124969951","https://openalex.org/W2945274617","https://openalex.org/W4313052709","https://openalex.org/W4298131179","https://openalex.org/W2375430703"],"abstract_inverted_index":{"Segmentation":[0],"of":[1,17,35],"white":[2],"blood":[3],"cells":[4,19],"(WBCs)":[5],"image":[6],"is":[7,62,108,119,142],"meaningful":[8],"but":[9,77,146],"challenging":[10,131],"due":[11],"to":[12,57,111],"the":[13,18,36,67,73,83,86,90,102,136,139,156],"complex":[14],"internal":[15],"characteristics":[16],"and":[20,26,40,101,163,169],"external":[21],"factors,":[22],"such":[23],"as":[24,99,126,128],"illumination":[25],"different":[27],"microscopic":[28],"views.":[29],"This":[30],"paper":[31],"addresses":[32],"two":[33],"problems":[34],"segmentation:":[37],"WBC":[38,75],"location":[39,68,91,162],"subimage":[41,84],"segmentation.":[42],"To":[43],"locate":[44],"WBCs,":[45],"a":[46,59,94,123,129],"method":[47],"that":[48,155],"uses":[49],"multiple":[50],"windows":[51],"obtained":[52],"by":[53],"scoring":[54],"multiscale":[55],"cues":[56],"extract":[58],"rectangular":[60],"region":[61],"proposed.":[63],"In":[64,82],"this":[65],"manner,":[66],"window":[69,92],"not":[70,143],"only":[71,144],"covers":[72],"whole":[74],"completely,":[76],"also":[78,147],"achieves":[79],"adaptive":[80],"adjustment.":[81],"segmentation,":[85],"subimages":[87],"preprocessed":[88],"from":[89],"with":[93,135],"replace":[95],"procedure":[96],"are":[97],"taken":[98],"initialization,":[100],"GrabCut":[103],"algorithm":[104,118,141,158],"based":[105],"on":[106],"dilation":[107],"iteratively":[109],"run":[110],"obtain":[112],"more":[113,130],"precise":[114],"results.":[115],"The":[116,152],"proposed":[117,140,157],"extensively":[120],"evaluated":[121],"using":[122],"CellaVision":[124],"dataset":[125],"well":[127],"Jiashan":[132],"dataset.":[133],"Compared":[134],"existing":[137],"methods,":[138,165],"concise,":[145],"can":[148],"produce":[149],"high-quality":[150],"segmentations.":[151],"results":[153],"demonstrate":[154],"consistently":[159],"outperforms":[160],"other":[161],"segmentation":[164],"yielding":[166],"higher":[167],"recall":[168],"better":[170],"precision":[171],"rates.":[172]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3}],"updated_date":"2026-03-18T14:38:29.013473","created_date":"2025-10-10T00:00:00"}