{"id":"https://openalex.org/W2087177425","doi":"https://doi.org/10.1109/jbhi.2014.2344102","title":"Beta-Band Frequency Peaks Inside the Subthalamic Nucleus as a Biomarker for Motor Improvement After Deep Brain Stimulation in Parkinson's Disease","display_name":"Beta-Band Frequency Peaks Inside the Subthalamic Nucleus as a Biomarker for Motor Improvement After Deep Brain Stimulation in Parkinson's Disease","publication_year":2014,"publication_date":"2014-07-30","ids":{"openalex":"https://openalex.org/W2087177425","doi":"https://doi.org/10.1109/jbhi.2014.2344102","mag":"2087177425","pmid":"https://pubmed.ncbi.nlm.nih.gov/25095273"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2014.2344102","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2014.2344102","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085322272","display_name":"Konstantinos P. Michmizos","orcid":"https://orcid.org/0000-0002-2584-7940"},"institutions":[{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I144112489","display_name":"McGovern Institute for Brain Research","ror":"https://ror.org/05ymca674","country_code":"US","type":"facility","lineage":["https://openalex.org/I144112489","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Konstantinos P. Michmizos","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Boston, MA, USA","Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA","McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210127055","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I144112489","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046967253","display_name":"Polytimi Frangou","orcid":"https://orcid.org/0000-0003-3524-0306"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Polytimi Frangou","raw_affiliation_strings":["Adaptive Brain Laboratory, Department of Psychology, University of Cambridge, Cambridge, U.K"],"affiliations":[{"raw_affiliation_string":"Adaptive Brain Laboratory, Department of Psychology, University of Cambridge, Cambridge, U.K","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087105075","display_name":"Pantelis Stathis","orcid":null},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Pantelis Stathis","raw_affiliation_strings":["Department of Neurology, Mediterraneo Hospital, Athens, Greece","Department of Neurosurgery, \u201cEvangelismos\u201d General Hospital, National and Kapodistrian University of Athens, Athens, Greece","Department of Neurosurgery, \"Evangelismos\" General Hospital, National and Kapodistrian University of Athens, Athens, Greece"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mediterraneo Hospital, Athens, Greece","institution_ids":[]},{"raw_affiliation_string":"Department of Neurosurgery, \u201cEvangelismos\u201d General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214"]},{"raw_affiliation_string":"Department of Neurosurgery, \"Evangelismos\" General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108713136","display_name":"Damianos E. Sakas","orcid":null},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Damianos Sakas","raw_affiliation_strings":["Department of Neurosurgery, \u201cEvangelismos\u201d General Hospital, National and Kapodistrian University of Athens, Athens, Greece","Department of Neurosurgery, \"Evangelismos\" General Hospital, National and Kapodistrian University of Athens, Athens, Greece"],"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, \u201cEvangelismos\u201d General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214"]},{"raw_affiliation_string":"Department of Neurosurgery, \"Evangelismos\" General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082313849","display_name":"Konstantina S. Nikita","orcid":"https://orcid.org/0000-0001-8255-4354"},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Konstantina S. Nikita","raw_affiliation_strings":["Biomedical Simulations and Imaging Laboratory, Faculty of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece"],"affiliations":[{"raw_affiliation_string":"Biomedical Simulations and Imaging Laboratory, Faculty of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I174458059"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5085322272"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I144112489","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":1.0319,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.76881464,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"19","issue":"1","first_page":"174","last_page":"180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"Deep brain stimulation","score":0.9450738430023193},{"id":"https://openalex.org/keywords/subthalamic-nucleus","display_name":"Subthalamic nucleus","score":0.9297069311141968},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.713302493095398},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.6121305823326111},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.592574954032898},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5550918579101562},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.4766462743282318},{"id":"https://openalex.org/keywords/beta-rhythm","display_name":"Beta Rhythm","score":0.47322356700897217},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.4730226993560791},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4580165445804596},{"id":"https://openalex.org/keywords/basal-ganglia","display_name":"Basal ganglia","score":0.43928948044776917},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4192747473716736},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.30895042419433594},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.2883686423301697},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.23773953318595886},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"Central nervous system","score":0.16839033365249634},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11832627654075623}],"concepts":[{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.9450738430023193},{"id":"https://openalex.org/C2777319143","wikidata":"https://www.wikidata.org/wiki/Q2270424","display_name":"Subthalamic nucleus","level":5,"score":0.9297069311141968},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.713302493095398},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6121305823326111},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.592574954032898},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5550918579101562},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.4766462743282318},{"id":"https://openalex.org/C2910144760","wikidata":"https://www.wikidata.org/wiki/Q831014","display_name":"Beta Rhythm","level":3,"score":0.47322356700897217},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4730226993560791},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4580165445804596},{"id":"https://openalex.org/C2778187257","wikidata":"https://www.wikidata.org/wiki/Q464210","display_name":"Basal ganglia","level":3,"score":0.43928948044776917},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4192747473716736},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.30895042419433594},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2883686423301697},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23773953318595886},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.16839033365249634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11832627654075623},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001611","descriptor_name":"Beta Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001611","descriptor_name":"Beta Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001611","descriptor_name":"Beta Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D009069","descriptor_name":"Movement Disorders","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019919","descriptor_name":"Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019919","descriptor_name":"Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019919","descriptor_name":"Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064795","descriptor_name":"Intraoperative Neurophysiological Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064795","descriptor_name":"Intraoperative Neurophysiological Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064795","descriptor_name":"Intraoperative Neurophysiological Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2014.2344102","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2014.2344102","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:25095273","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25095273","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6600000262260437,"display_name":"No poverty","id":"https://metadata.un.org/sdg/1"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1971283363","https://openalex.org/W1982394722","https://openalex.org/W1983965289","https://openalex.org/W1999318740","https://openalex.org/W2000963066","https://openalex.org/W2003581012","https://openalex.org/W2009543464","https://openalex.org/W2011887884","https://openalex.org/W2016358077","https://openalex.org/W2022280818","https://openalex.org/W2022385615","https://openalex.org/W2024564270","https://openalex.org/W2025203077","https://openalex.org/W2029940240","https://openalex.org/W2037608973","https://openalex.org/W2043796909","https://openalex.org/W2045116961","https://openalex.org/W2045989321","https://openalex.org/W2046910164","https://openalex.org/W2053727139","https://openalex.org/W2054472230","https://openalex.org/W2058691511","https://openalex.org/W2070149136","https://openalex.org/W2073248892","https://openalex.org/W2074191835","https://openalex.org/W2079369992","https://openalex.org/W2084910998","https://openalex.org/W2085073811","https://openalex.org/W2091474479","https://openalex.org/W2091527263","https://openalex.org/W2094679226","https://openalex.org/W2096699700","https://openalex.org/W2100365094","https://openalex.org/W2106822551","https://openalex.org/W2108157570","https://openalex.org/W2124227727","https://openalex.org/W2127146698","https://openalex.org/W2131918703","https://openalex.org/W2138986042","https://openalex.org/W2140978740","https://openalex.org/W2141405085","https://openalex.org/W2141881609","https://openalex.org/W2143126434","https://openalex.org/W2147306744","https://openalex.org/W2156785179","https://openalex.org/W2159924449","https://openalex.org/W2161472384","https://openalex.org/W2168860829","https://openalex.org/W2231485474","https://openalex.org/W2328435466","https://openalex.org/W2401500688","https://openalex.org/W3025643029","https://openalex.org/W4293857795"],"related_works":["https://openalex.org/W2060063293","https://openalex.org/W2093780015","https://openalex.org/W4289755640","https://openalex.org/W2913536894","https://openalex.org/W4301179225","https://openalex.org/W2607326016","https://openalex.org/W1983965289","https://openalex.org/W22241804","https://openalex.org/W1564112868","https://openalex.org/W1936532143"],"abstract_inverted_index":{"Deep":[0],"brain":[1],"stimulation":[2,27,180],"(DBS)":[3],"of":[4,28,94,122,178],"the":[5,29,52,82,92,95,167,172,176,179,188,207],"subthalamic":[6],"nucleus":[7],"(STN)":[8],"remains":[9],"an":[10],"empirical,":[11],"yet":[12],"highly":[13],"effective,":[14],"surgical":[15],"treatment":[16],"for":[17,91],"advanced":[18],"Parkinson's":[19],"disease":[20],"(PD).":[21],"DBS":[22,130,155],"outcome":[23],"depends":[24],"on":[25,133],"accurate":[26],"STN":[30,96,208],"sensorimotor":[31,97,209],"area":[32,210],"which":[33],"is":[34,56],"a":[35,57,89,138],"trial-and-error":[36],"procedure":[37],"taking":[38],"place":[39],"during":[40],"and":[41,86,105,112,128,141,175,202],"after":[42,117],"surgery.":[43],"Pathologically":[44],"enhanced":[45],"beta-band":[46,69],"(13-35":[47],"Hz)":[48],"oscillatory":[49],"activity":[50],"across":[51,171],"cortico-basal":[53],"ganglia":[54],"pathways":[55],"prominent":[58],"neurophysiological":[59],"phenomenon":[60],"associated":[61,211],"with":[62,103,212],"PD.":[63],"We":[64,99,125],"hypothesized":[65],"that":[66],"weighing":[67],"together":[68],"frequency":[70],"peaks":[71],"from":[72],"simultaneous":[73],"microelectrode":[74],"recordings":[75],"in":[76,145,158,187,205],"\"off-state\"":[77],"PD":[78,148],"patients":[79,107],"could":[80,198],"map":[81],"individual":[83],"neuroanatomical":[84],"variability":[85],"serve":[87],"as":[88],"biomarker":[90,197],"location":[93],"neurons.":[98],"validated":[100],"our":[101],"hypothesis":[102],"9":[104],"11":[106],"that,":[108],"respectively,":[109,144],"responded":[110],"well":[111],"poorly":[113],"to":[114],"bilateral":[115],"DBS,":[116],"at":[118],"least":[119],"two":[120,189],"years":[121],"follow":[123],"up.":[124],"categorized":[126],"\"good\"":[127],"\"poor\"":[129],"responders":[131,156],"based":[132],"their":[134],"clinical":[135,215],"assessment":[136],"alongside":[137],">":[139],"40%":[140],"<30%":[142],"change,":[143],"\"off\"":[146],"unified":[147],"rating":[149],"scale":[150],"motor":[151],"scores.":[152],"Good":[153],"(poor)":[154],"had,":[157],"average,":[159],"1":[160],"mm":[161],"(3.5":[162],"mm)":[163],"vertical":[164],"distance":[165],"between":[166],"maximum":[168],"beta-peak":[169],"weighted":[170],"parallel":[173],"microelectrodes":[174],"center":[177],"area.":[181],"The":[182],"distances":[183],"were":[184],"statistically":[185],"different":[186],"groups":[190],"(":[191],"p":[192],"=":[193],"0.0025":[194],").":[195],"Our":[196],"provide":[199],"personalized":[200],"intra-":[201],"postoperative":[203],"support":[204],"stimulating":[206],"optimal":[213],"long-term":[214],"benefits.":[216]},"counts_by_year":[{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}