{"id":"https://openalex.org/W2036483402","doi":"https://doi.org/10.1109/jbhi.2013.2295262","title":"On the Identification of Circulating Tumor Cells in Breast Cancer","display_name":"On the Identification of Circulating Tumor Cells in Breast Cancer","publication_year":2014,"publication_date":"2014-01-31","ids":{"openalex":"https://openalex.org/W2036483402","doi":"https://doi.org/10.1109/jbhi.2013.2295262","mag":"2036483402","pmid":"https://pubmed.ncbi.nlm.nih.gov/24808221"},"language":"en","primary_location":{"id":"doi:10.1109/jbhi.2013.2295262","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2013.2295262","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012956979","display_name":"Stelios Sfakianakis","orcid":"https://orcid.org/0000-0001-8424-4157"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Stelios Sfakianakis","raw_affiliation_strings":["Foundation for Research and Technology Hellas, Institute of Computer Science, Heraklion, Greece","Inst. of Comput. Sci., Found. for Res. & Technol. Hellas, Heraklion, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology Hellas, Institute of Computer Science, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]},{"raw_affiliation_string":"Inst. of Comput. Sci., Found. for Res. & Technol. Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086247449","display_name":"Ekaterini S. Bei","orcid":null},"institutions":[{"id":"https://openalex.org/I142617266","display_name":"University of Crete","ror":"https://ror.org/00dr28g20","country_code":"GR","type":"education","lineage":["https://openalex.org/I142617266"]},{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Ekaterini S. Bei","raw_affiliation_strings":["Department of Electronic and Computer Engineering, Technical University of Crete, Chania, Greece","Dept. of Electron. & Comput. Eng., Tech. Univ. of Crete, Chania, Greece#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electronic and Computer Engineering, Technical University of Crete, Chania, Greece","institution_ids":["https://openalex.org/I55741626"]},{"raw_affiliation_string":"Dept. of Electron. & Comput. Eng., Tech. Univ. of Crete, Chania, Greece#TAB#","institution_ids":["https://openalex.org/I142617266"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113661535","display_name":"Michalis Zervakis","orcid":null},"institutions":[{"id":"https://openalex.org/I142617266","display_name":"University of Crete","ror":"https://ror.org/00dr28g20","country_code":"GR","type":"education","lineage":["https://openalex.org/I142617266"]},{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Michalis Zervakis","raw_affiliation_strings":["Department of Electronic and Computer Engineering, Technical University of Crete, Chania, Greece","Dept. of Electron. & Comput. Eng., Tech. Univ. of Crete, Chania, Greece#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electronic and Computer Engineering, Technical University of Crete, Chania, Greece","institution_ids":["https://openalex.org/I55741626"]},{"raw_affiliation_string":"Dept. of Electron. & Comput. Eng., Tech. Univ. of Crete, Chania, Greece#TAB#","institution_ids":["https://openalex.org/I142617266"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013164211","display_name":"Despoina Vassou","orcid":"https://orcid.org/0000-0002-4306-1108"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Despoina Vassou","raw_affiliation_strings":["Foundation for Research and Technology Hellas, Institute of Molecular Biology and Biotechnology, Heraklion, Greece","Inst. of Mol. Biol. & Biotechnol, Found. for Res. & Technol. Hellas, Heraklion, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology Hellas, Institute of Molecular Biology and Biotechnology, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]},{"raw_affiliation_string":"Inst. of Mol. Biol. & Biotechnol, Found. for Res. & Technol. Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024607981","display_name":"Dimitrios Kafetzopoulos","orcid":"https://orcid.org/0000-0002-0081-9409"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios Kafetzopoulos","raw_affiliation_strings":["Foundation for Research and Technology Hellas, Institute of Molecular Biology and Biotechnology, Heraklion, Greece","Inst. of Mol. Biol. & Biotechnol, Found. for Res. & Technol. Hellas, Heraklion, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation for Research and Technology Hellas, Institute of Molecular Biology and Biotechnology, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]},{"raw_affiliation_string":"Inst. of Mol. Biol. & Biotechnol, Found. for Res. & Technol. Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I8901234"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.918,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.86587902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"18","issue":"3","first_page":"773","last_page":"782"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.946399986743927,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circulating-tumor-cell","display_name":"Circulating tumor cell","score":0.7989746332168579},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.7780215740203857},{"id":"https://openalex.org/keywords/ca15-3","display_name":"CA15-3","score":0.5633242130279541},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5515854954719543},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5436616539955139},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.5203347206115723},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"Lung cancer","score":0.5189763903617859},{"id":"https://openalex.org/keywords/metastasis","display_name":"Metastasis","score":0.5069406032562256},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.33685386180877686},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.27891018986701965}],"concepts":[{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.7989746332168579},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7780215740203857},{"id":"https://openalex.org/C118646709","wikidata":"https://www.wikidata.org/wiki/Q1657620","display_name":"CA15-3","level":4,"score":0.5633242130279541},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5515854954719543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5436616539955139},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5203347206115723},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5189763903617859},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5069406032562256},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.33685386180877686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27891018986701965}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/jbhi.2013.2295262","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jbhi.2013.2295262","pdf_url":null,"source":{"id":"https://openalex.org/S2495854775","display_name":"IEEE Journal of Biomedical and Health Informatics","issn_l":"2168-2194","issn":["2168-2194","2168-2208"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Journal of Biomedical and Health Informatics","raw_type":"journal-article"},{"id":"pmid:24808221","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24808221","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE journal of biomedical and health informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.47999998927116394}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W72712630","https://openalex.org/W1484870202","https://openalex.org/W1525223998","https://openalex.org/W1531214929","https://openalex.org/W1965606609","https://openalex.org/W1968328642","https://openalex.org/W1968464607","https://openalex.org/W1973813521","https://openalex.org/W1978042970","https://openalex.org/W1980548655","https://openalex.org/W1980574509","https://openalex.org/W1982191152","https://openalex.org/W1984375010","https://openalex.org/W1987249178","https://openalex.org/W1987293404","https://openalex.org/W1995916005","https://openalex.org/W1995951336","https://openalex.org/W2002876292","https://openalex.org/W2016451402","https://openalex.org/W2018486347","https://openalex.org/W2019223707","https://openalex.org/W2020541351","https://openalex.org/W2027769492","https://openalex.org/W2034269086","https://openalex.org/W2036809882","https://openalex.org/W2044527070","https://openalex.org/W2045412692","https://openalex.org/W2060993043","https://openalex.org/W2069686000","https://openalex.org/W2074465378","https://openalex.org/W2078877034","https://openalex.org/W2087446092","https://openalex.org/W2096192437","https://openalex.org/W2096863518","https://openalex.org/W2103365735","https://openalex.org/W2107665951","https://openalex.org/W2110065044","https://openalex.org/W2111758831","https://openalex.org/W2112995207","https://openalex.org/W2116053761","https://openalex.org/W2117692326","https://openalex.org/W2124640147","https://openalex.org/W2128173047","https://openalex.org/W2128952169","https://openalex.org/W2137028370","https://openalex.org/W2143878386","https://openalex.org/W2146060062","https://openalex.org/W2148823465","https://openalex.org/W2152155643","https://openalex.org/W2153795693","https://openalex.org/W2157795344","https://openalex.org/W2160697532","https://openalex.org/W2167980479","https://openalex.org/W2329066425","https://openalex.org/W4294107304","https://openalex.org/W6631560462","https://openalex.org/W6655177529"],"related_works":["https://openalex.org/W3160695097","https://openalex.org/W2766672491","https://openalex.org/W3030986903","https://openalex.org/W2979892935","https://openalex.org/W377899687","https://openalex.org/W2383305151","https://openalex.org/W3088410393","https://openalex.org/W2395906155","https://openalex.org/W3033874287","https://openalex.org/W2144318661"],"abstract_inverted_index":{"Breast":[0],"cancer":[1,75,122,152],"is":[2,18,76],"a":[3,130],"highly":[4],"heterogeneous":[5],"disease":[6],"and":[7,33,39,56,66,88,123],"very":[8],"common":[9],"among":[10],"western":[11],"women.":[12],"The":[13,41],"main":[14],"cause":[15],"of":[16,43,82,91,103,114,137,146,158],"death":[17],"not":[19],"the":[20,80,101,112,135,144],"primary":[21],"tumor":[22,45,53,64],"but":[23],"its":[24],"metastases":[25],"at":[26],"distant":[27],"sites,":[28],"such":[29,115],"as":[30],"lymph":[31],"nodes":[32],"other":[34],"organs":[35],"(preferentially":[36],"lung,":[37],"liver,":[38],"bones).":[40],"study":[42],"circulating":[44],"cells":[46],"(CTCs)":[47],"in":[48,95,105,150],"peripheral":[49,106,124],"blood":[50,107,125],"resulting":[51],"from":[52],"cell":[54],"invasion":[55],"intravascular":[57],"filtration":[58],"highlights":[59],"their":[60,86],"crucial":[61],"role":[62],"concerning":[63],"aggressiveness":[65],"metastasis.":[67],"Genomic":[68],"research":[69],"regarding":[70],"CTCs":[71,159],"monitoring":[72],"for":[73,85,134],"breast":[74,121,151],"limited":[77],"due":[78],"to":[79],"lack":[81],"indicative":[83,157],"genes":[84,148],"detection":[87],"isolation.":[89],"Instead":[90],"direct":[92],"CTC":[93],"detection,":[94],"our":[96],"study,":[97],"we":[98,128],"focus":[99],"on":[100],"identification":[102,136,145],"factors":[104],"that":[108],"can":[109],"indirectly":[110],"reveal":[111],"presence":[113],"cells.":[116],"Using":[117],"selected":[118],"publicly":[119],"available":[120],"microarray":[126],"datasets,":[127],"follow":[129],"two-step":[131],"elimination":[132],"procedure":[133,142],"several":[138],"discriminant":[139],"factors.":[140],"Our":[141],"facilitates":[143],"major":[147],"involved":[149],"pathology,":[153],"which":[154],"are":[155],"also":[156],"presence.":[160]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}