{"id":"https://openalex.org/W4416895193","doi":"https://doi.org/10.1109/jas.2025.125609","title":"Robust Brain Tumor Segmentation with Incomplete MRI Modalities Using H\u00f6lder Divergence and Mutual Information-Enhanced Knowledge Transfer","display_name":"Robust Brain Tumor Segmentation with Incomplete MRI Modalities Using H\u00f6lder Divergence and Mutual Information-Enhanced Knowledge Transfer","publication_year":2026,"publication_date":"2026-04-01","ids":{"openalex":"https://openalex.org/W4416895193","doi":"https://doi.org/10.1109/jas.2025.125609"},"language":"en","primary_location":{"id":"doi:10.1109/jas.2025.125609","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jas.2025.125609","pdf_url":null,"source":{"id":"https://openalex.org/S2484288132","display_name":"IEEE/CAA Journal of Automatica Sinica","issn_l":"2329-9266","issn":["2329-9266","2329-9274"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/CAA Journal of Automatica Sinica","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2507.01254","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028223858","display_name":"Runze Cheng","orcid":"https://orcid.org/0000-0001-6410-8975"},"institutions":[{"id":"https://openalex.org/I4210152380","display_name":"Shenzhen Technology University","ror":"https://ror.org/04qzpec27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152380"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Runze Cheng","raw_affiliation_strings":["MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172"],"raw_orcid":"https://orcid.org/0009-0002-5189-2929","affiliations":[{"raw_affiliation_string":"MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172","institution_ids":["https://openalex.org/I4210152380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108978360","display_name":"Xihang Qiu","orcid":"https://orcid.org/0009-0001-9103-8025"},"institutions":[{"id":"https://openalex.org/I4210152380","display_name":"Shenzhen Technology University","ror":"https://ror.org/04qzpec27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152380"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xihang Qiu","raw_affiliation_strings":["MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172"],"raw_orcid":"https://orcid.org/0009-0001-9103-8025","affiliations":[{"raw_affiliation_string":"MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172","institution_ids":["https://openalex.org/I4210152380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351421","display_name":"Ming Li","orcid":"https://orcid.org/0000-0002-4073-0273"},"institutions":[{"id":"https://openalex.org/I4210100255","display_name":"Beijing Academy of Artificial Intelligence","ror":"https://ror.org/016a74861","country_code":"CN","type":"other","lineage":["https://openalex.org/I4210100255"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Li","raw_affiliation_strings":["Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ),Shenzhen,China,518083"],"raw_orcid":"https://orcid.org/0000-0002-7852-0159","affiliations":[{"raw_affiliation_string":"Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ),Shenzhen,China,518083","institution_ids":["https://openalex.org/I4210100255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100449346","display_name":"Ye Zhang","orcid":"https://orcid.org/0000-0003-0709-3767"},"institutions":[{"id":"https://openalex.org/I4210152380","display_name":"Shenzhen Technology University","ror":"https://ror.org/04qzpec27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152380"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Zhang","raw_affiliation_strings":["MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172"],"raw_orcid":"https://orcid.org/0000-0003-4023-6352","affiliations":[{"raw_affiliation_string":"MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172","institution_ids":["https://openalex.org/I4210152380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100373880","display_name":"Chun Li","orcid":"https://orcid.org/0000-0001-7916-2800"},"institutions":[{"id":"https://openalex.org/I4210100255","display_name":"Beijing Academy of Artificial Intelligence","ror":"https://ror.org/016a74861","country_code":"CN","type":"other","lineage":["https://openalex.org/I4210100255"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Richard Yu","raw_affiliation_strings":["Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ),Shenzhen,China,518083"],"raw_orcid":"https://orcid.org/0000-0003-1006-7594","affiliations":[{"raw_affiliation_string":"Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ),Shenzhen,China,518083","institution_ids":["https://openalex.org/I4210100255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075958056","display_name":"Fei Yu","orcid":"https://orcid.org/0000-0001-8854-5707"},"institutions":[{"id":"https://openalex.org/I4210152380","display_name":"Shenzhen Technology University","ror":"https://ror.org/04qzpec27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152380"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chun Li","raw_affiliation_strings":["MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172"],"raw_orcid":"https://orcid.org/0000-0002-2021-751X","affiliations":[{"raw_affiliation_string":"MSU-BIT-SMBU Joint Research Center of Applied Mathematics, Shenzhen MSU-BIT University,Shenzhen,China,518172","institution_ids":["https://openalex.org/I4210152380"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5028223858"],"corresponding_institution_ids":["https://openalex.org/I4210152380"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01064456,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"4","first_page":"939","last_page":"954"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.7802000045776367,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.7802000045776367,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.15649999678134918,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.022600000724196434,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/divergence","display_name":"Divergence (linguistics)","score":0.6086999773979187},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5705000162124634},{"id":"https://openalex.org/keywords/modalities","display_name":"Modalities","score":0.5429999828338623},{"id":"https://openalex.org/keywords/mutual-information","display_name":"Mutual information","score":0.5260999798774719},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45820000767707825},{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.44279998540878296},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.3736000061035156},{"id":"https://openalex.org/keywords/modality","display_name":"Modality (human\u2013computer interaction)","score":0.3517000079154968}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7156000137329102},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6527000069618225},{"id":"https://openalex.org/C207390915","wikidata":"https://www.wikidata.org/wiki/Q1230525","display_name":"Divergence (linguistics)","level":2,"score":0.6086999773979187},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5705000162124634},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.5429999828338623},{"id":"https://openalex.org/C152139883","wikidata":"https://www.wikidata.org/wiki/Q252973","display_name":"Mutual information","level":2,"score":0.5260999798774719},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45820000767707825},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.44279998540878296},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.3736000061035156},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.36329999566078186},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.3517000079154968},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.34040001034736633},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.3352000117301941},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.31029999256134033},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3095000088214874},{"id":"https://openalex.org/C171752962","wikidata":"https://www.wikidata.org/wiki/Q255166","display_name":"Kullback\u2013Leibler divergence","level":2,"score":0.30219998955726624},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.28450000286102295},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.2782999873161316},{"id":"https://openalex.org/C2776175482","wikidata":"https://www.wikidata.org/wiki/Q1195816","display_name":"Transfer (computing)","level":2,"score":0.2709999978542328},{"id":"https://openalex.org/C100776233","wikidata":"https://www.wikidata.org/wiki/Q2532492","display_name":"Bridge (graph theory)","level":2,"score":0.26980000734329224},{"id":"https://openalex.org/C160920958","wikidata":"https://www.wikidata.org/wiki/Q7662746","display_name":"Synthetic data","level":2,"score":0.2680000066757202},{"id":"https://openalex.org/C157787499","wikidata":"https://www.wikidata.org/wiki/Q13479657","display_name":"Real-time MRI","level":3,"score":0.25780001282691956},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.2567000091075897},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.250900000333786},{"id":"https://openalex.org/C113336015","wikidata":"https://www.wikidata.org/wiki/Q574010","display_name":"Complete information","level":2,"score":0.25060001015663147}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/jas.2025.125609","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jas.2025.125609","pdf_url":null,"source":{"id":"https://openalex.org/S2484288132","display_name":"IEEE/CAA Journal of Automatica Sinica","issn_l":"2329-9266","issn":["2329-9266","2329-9274"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE/CAA Journal of Automatica Sinica","raw_type":"journal-article"},{"id":"pmh:oai:arXiv.org:2507.01254","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2507.01254","pdf_url":"https://arxiv.org/pdf/2507.01254","source":{"id":"https://openalex.org/S4393918464","display_name":"ArXiv.org","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2507.01254","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2507.01254","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2507.01254","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2507.01254","pdf_url":"https://arxiv.org/pdf/2507.01254","source":{"id":"https://openalex.org/S4393918464","display_name":"ArXiv.org","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1408260344","display_name":null,"funder_award_id":"2025YFE0113400,2022YFC3310300","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G1561475922","display_name":null,"funder_award_id":"2024A15150 11774","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G2680068897","display_name":null,"funder_award_id":"Z210001","funder_id":"https://openalex.org/F4320322919","funder_display_name":"Natural Science Foundation of Beijing Municipality"},{"id":"https://openalex.org/G8363470664","display_name":null,"funder_award_id":"12171036","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322919","display_name":"Natural Science Foundation of Beijing Municipality","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320337111","display_name":"Basic and Applied Basic Research Foundation of Guangdong Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Multimodal":[0],"MRI":[1],"(magnetic":[2],"resonance":[3],"imaging)":[4],"provides":[5],"critical":[6],"complementary":[7],"information":[8],"for":[9],"accurate":[10,97],"brain":[11],"tumor":[12],"segmentation.":[13,98],"However,":[14],"conventional":[15],"methods":[16,114],"struggle":[17],"when":[18],"certain":[19],"modalities":[20],"are":[21],"missing":[22,117],"due":[23],"to":[24,126],"issues":[25],"like":[26],"image":[27],"quality,":[28],"protocol":[29],"inconsistencies,":[30],"patient":[31],"allergies,":[32],"or":[33],"financial":[34],"constraints.":[35],"To":[36],"address":[37],"this,":[38],"we":[39],"propose":[40],"a":[41],"robust":[42],"single-modality":[43],"parallel":[44],"processing":[45],"framework":[46,85],"that":[47],"achieves":[48],"high":[49],"segmentation":[50],"accuracy":[51],"even":[52],"with":[53,119],"incomplete":[54],"modalities.":[55],"Leveraging":[56],"H\u00f6lder":[57],"divergence":[58,79],"and":[59,80,91,105],"mutual":[60],"information,":[61],"our":[62],"model":[63],"maintains":[64],"modality-specific":[65],"features":[66],"while":[67],"dynamically":[68],"adjusting":[69],"network":[70],"parameters":[71],"based":[72],"on":[73,101],"available":[74],"inputs.":[75],"By":[76],"using":[77],"these":[78],"information-based":[81],"loss":[82],"functions,":[83],"the":[84,102,127],"effectively":[86],"quantifies":[87],"discrepancies":[88],"between":[89],"predictions":[90],"ground-truth":[92],"labels,":[93],"resulting":[94],"in":[95,115],"consistently":[96],"Extensive":[99],"evaluations":[100],"BraTS":[103,106],"2018":[104],"2020":[107],"datasets":[108],"demonstrate":[109],"superior":[110],"performance":[111],"over":[112],"existing":[113],"handling":[116],"modalities,":[118],"ablation":[120],"studies":[121],"validating":[122],"each":[123],"component's":[124],"contribution":[125],"framework.":[128]},"counts_by_year":[],"updated_date":"2026-05-06T06:03:25.996018","created_date":"2025-10-10T00:00:00"}