{"id":"https://openalex.org/W2164808534","doi":"https://doi.org/10.1109/itw.2008.4578630","title":"On new stochastic approaches for solving forward and backward problems of biochemical networks","display_name":"On new stochastic approaches for solving forward and backward problems of biochemical networks","publication_year":2008,"publication_date":"2008-05-01","ids":{"openalex":"https://openalex.org/W2164808534","doi":"https://doi.org/10.1109/itw.2008.4578630","mag":"2164808534"},"language":"en","primary_location":{"id":"doi:10.1109/itw.2008.4578630","is_oa":false,"landing_page_url":"https://doi.org/10.1109/itw.2008.4578630","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 IEEE Information Theory Workshop","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006962534","display_name":"Petar M. Djuri\u0107","orcid":"https://orcid.org/0000-0001-7791-3199"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Petar M. Djuric","raw_affiliation_strings":["Dept. Electrical and Computer Eng., Stony Brook University, NY"],"affiliations":[{"raw_affiliation_string":"Dept. Electrical and Computer Eng., Stony Brook University, NY","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058778434","display_name":"M\u00f3nica F. Bugallo","orcid":"https://orcid.org/0000-0003-2963-1474"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monica F. Bugallo","raw_affiliation_strings":["Dept. Electrical and Computer Eng., Stony Brook University, Stony Brook, NY, USA"],"affiliations":[{"raw_affiliation_string":"Dept. Electrical and Computer Eng., Stony Brook University, Stony Brook, NY, USA","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016880244","display_name":"Vibha Mane","orcid":"https://orcid.org/0000-0001-9071-7715"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vibha Mane","raw_affiliation_strings":["Dept. Electrical and Computer Eng., Stony Brook University, Stony Brook, NY, USA"],"affiliations":[{"raw_affiliation_string":"Dept. Electrical and Computer Eng., Stony Brook University, Stony Brook, NY, USA","institution_ids":["https://openalex.org/I59553526"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5006962534"],"corresponding_institution_ids":["https://openalex.org/I59553526"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13022444,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":null,"first_page":"99","last_page":"103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9930999875068665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inverse-problem","display_name":"Inverse problem","score":0.6374075412750244},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6299855709075928},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.6250879764556885},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.542930006980896},{"id":"https://openalex.org/keywords/monte-carlo-method","display_name":"Monte Carlo method","score":0.542062520980835},{"id":"https://openalex.org/keywords/particle-filter","display_name":"Particle filter","score":0.5373916029930115},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3391657769680023},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.32847684621810913},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2621646225452423},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16690334677696228},{"id":"https://openalex.org/keywords/kalman-filter","display_name":"Kalman filter","score":0.08158871531486511}],"concepts":[{"id":"https://openalex.org/C135252773","wikidata":"https://www.wikidata.org/wiki/Q1567213","display_name":"Inverse problem","level":2,"score":0.6374075412750244},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6299855709075928},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.6250879764556885},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.542930006980896},{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.542062520980835},{"id":"https://openalex.org/C52421305","wikidata":"https://www.wikidata.org/wiki/Q1151499","display_name":"Particle filter","level":3,"score":0.5373916029930115},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3391657769680023},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.32847684621810913},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2621646225452423},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16690334677696228},{"id":"https://openalex.org/C157286648","wikidata":"https://www.wikidata.org/wiki/Q846780","display_name":"Kalman filter","level":2,"score":0.08158871531486511},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/itw.2008.4578630","is_oa":false,"landing_page_url":"https://doi.org/10.1109/itw.2008.4578630","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 IEEE Information Theory Workshop","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6600000262260437,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1483307070","https://openalex.org/W1499965417","https://openalex.org/W1946177469","https://openalex.org/W1968856189","https://openalex.org/W2030551718","https://openalex.org/W2085266415","https://openalex.org/W2093179886","https://openalex.org/W2148613679","https://openalex.org/W2155418451","https://openalex.org/W2165609874","https://openalex.org/W2185269062","https://openalex.org/W2294875987","https://openalex.org/W4255133955","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2015530857","https://openalex.org/W2556064263","https://openalex.org/W1991846142","https://openalex.org/W1583020711","https://openalex.org/W2943623134","https://openalex.org/W2494523064","https://openalex.org/W2393870460","https://openalex.org/W1497573972","https://openalex.org/W2071659383","https://openalex.org/W1846253165"],"abstract_inverted_index":{"There":[0],"are":[1,14,27,74,79],"two":[2,93,112],"distinct":[3],"problems":[4],"in":[5,36,47,62],"the":[6,17,24,40,45,49,54,60,63,69,82,89,92,100,104,121,138],"stochastic":[7],"analysis":[8],"of":[9,23,33,53,59,81,84,86,88,103],"biochemical":[10,70],"networks,":[11],"and":[12,19],"they":[13],"known":[15],"as":[16],"forward":[18,122],"inverse":[20,139],"problems.":[21,118],"Solutions":[22,52],"former":[25],"problem":[26,56,123,140],"used":[28],"for":[29,115,136],"simulating":[30],"a":[31,126],"system":[32,64],"molecular":[34],"species":[35,50],"time":[37],"according":[38],"to":[39],"random":[41],"laws":[42],"that":[43,65,78,128],"govern":[44],"reactions":[46],"which":[48],"participate.":[51],"latter":[55],"provide":[57],"estimates":[58,73],"unknowns":[61],"is":[66],"represented":[67],"by":[68],"network.":[71,106],"The":[72],"obtained":[75],"from":[76],"measurements":[77],"functions":[80],"number":[83],"molecules":[85],"some":[87],"species.":[90],"In":[91,107],"problems,":[94],"we":[95,110,124,141],"have":[96],"underlying":[97],"assumptions":[98],"about":[99],"probabilistic":[101],"models":[102],"studied":[105],"this":[108],"paper":[109],"present":[111],"new":[113],"methods":[114],"addressing":[116],"these":[117],"For":[119],"solving":[120,137],"propose":[125],"method":[127],"does":[129],"not":[130],"employ":[131],"Monte":[132],"Carlo":[133],"simulations,":[134],"whereas":[135],"use":[142],"particle":[143],"filtering.":[144]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}