{"id":"https://openalex.org/W4399768945","doi":"https://doi.org/10.1109/isoen61239.2024.10556109","title":"Simulating Olfactory System in vitro based on a Transwell Co-culture Model","display_name":"Simulating Olfactory System in vitro based on a Transwell Co-culture Model","publication_year":2024,"publication_date":"2024-05-12","ids":{"openalex":"https://openalex.org/W4399768945","doi":"https://doi.org/10.1109/isoen61239.2024.10556109"},"language":"en","primary_location":{"id":"doi:10.1109/isoen61239.2024.10556109","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isoen61239.2024.10556109","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101829648","display_name":"Mengxue Liu","orcid":"https://orcid.org/0000-0003-3779-6789"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Mengxue Liu","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015668757","display_name":"Nan Jiang","orcid":"https://orcid.org/0000-0001-9221-9568"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Nan Jiang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049126182","display_name":"Qifei Wang","orcid":"https://orcid.org/0000-0002-9365-0373"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qifei Wang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100430530","display_name":"Yajie Zhang","orcid":"https://orcid.org/0000-0003-2510-6015"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yajie Zhang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111232437","display_name":"Shunuo Shang","orcid":null},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shunuo Shang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100338622","display_name":"Liujing Zhuang","orcid":"https://orcid.org/0000-0001-9607-1302"},"institutions":[{"id":"https://openalex.org/I4210123185","display_name":"Zhejiang Lab","ror":"https://ror.org/02m2h7991","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210123185"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liujing Zhuang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","The MOE Frontier Science Center for Brain Science & Brain-machine Integration, Zhejiang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"The MOE Frontier Science Center for Brain Science & Brain-machine Integration, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210123185","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100338600","display_name":"Ping Wang","orcid":"https://orcid.org/0000-0001-6474-2722"},"institutions":[{"id":"https://openalex.org/I4210123185","display_name":"Zhejiang Lab","ror":"https://ror.org/02m2h7991","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210123185"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Wang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","The MOE Frontier Science Center for Brain Science & Brain-machine Integration, Zhejiang University, Hangzhou, China"],"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"The MOE Frontier Science Center for Brain Science & Brain-machine Integration, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210123185","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5101829648"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08970711,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.6507846117019653},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.503788411617279},{"id":"https://openalex.org/keywords/olfactory-system","display_name":"Olfactory system","score":0.4320109784603119},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.3242751359939575},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.23073232173919678},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2210012674331665}],"concepts":[{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6507846117019653},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.503788411617279},{"id":"https://openalex.org/C201792869","wikidata":"https://www.wikidata.org/wiki/Q1054094","display_name":"Olfactory system","level":2,"score":0.4320109784603119},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3242751359939575},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.23073232173919678},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2210012674331665},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isoen61239.2024.10556109","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isoen61239.2024.10556109","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5600000023841858,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1483715699","https://openalex.org/W2057038893","https://openalex.org/W2069186336","https://openalex.org/W2922105518","https://openalex.org/W3097347715","https://openalex.org/W3193542643","https://openalex.org/W4211240480","https://openalex.org/W4307947537","https://openalex.org/W4388680535"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052","https://openalex.org/W2382290278","https://openalex.org/W4395014643"],"abstract_inverted_index":{"The":[0],"sense":[1],"of":[2,33,59,68,147,166],"smell":[3],"is":[4,42],"quite":[5],"important":[6],"for":[7,161],"vital":[8],"functions":[9],"such":[10],"as":[11],"warning":[12],"and":[13,18,30,81,88,111,140,169],"protection":[14],"from":[15],"environmental":[16],"hazards,":[17],"social":[19],"communication.":[20],"However,":[21],"there":[22],"still":[23],"need":[24,73],"to":[25,44,74,106,112,150],"study":[26,107],"the":[27,37,60,64,69,78,85,97,148,152,163],"encoding":[28],"mechanism":[29,32,165],"perception":[31,168],"olfactory":[34,38,48,61,70,86,89,122,153,167],"information":[35,170],"in":[36,56,98,117],"system.":[39,154],"Therefore,":[40],"it":[41,104],"necessary":[43],"establish":[45],"an":[46],"effective":[47],"model.":[49],"Most":[50],"studies":[51],"have":[52],"focused":[53],"on":[54,128,144],"changes":[55],"one":[57],"part":[58],"system,":[62],"but":[63],"connections":[65,80,133],"between":[66,84,109],"parts":[67],"system":[71,123],"also":[72],"be":[75],"studied,":[76],"especially":[77],"neural":[79,115],"coding":[82],"mechanisms":[83],"epithelium":[87],"bulb.":[90],"For":[91],"co-culture":[92,121],"techniques":[93],"can":[94],"nearly":[95],"mimic":[96],"vivo":[99],"environment,":[100],"which":[101],"has":[102],"made":[103],"possible":[105],"interactions":[108],"neurons":[110],"reproduce":[113],"complex":[114],"circuits":[116],"vitro.":[118],"Here,":[119],"a":[120,158],"model":[124,156],"was":[125],"established":[126,135],"based":[127],"Transwell":[129],"microporous":[130],"membrane.":[131],"Neural":[132],"were":[134],"by":[136],"culturing":[137],"OE":[138],"organoids":[139],"OB":[141],"neuronal":[142],"network":[143],"both":[145],"sides":[146],"membrane":[149],"simulate":[151],"This":[155],"provides":[157],"promising":[159],"tool":[160],"exploring":[162],"molecular":[164],"encoding.":[171]},"counts_by_year":[],"updated_date":"2025-12-22T23:10:17.713674","created_date":"2025-10-10T00:00:00"}