{"id":"https://openalex.org/W4281748688","doi":"https://doi.org/10.1109/isoen54820.2022.9789617","title":"A Spiking Neural Network-based Olfactory Bionic Model for Periodontal Diseases Screening by Exhaled Breath with Electronic Nose","display_name":"A Spiking Neural Network-based Olfactory Bionic Model for Periodontal Diseases Screening by Exhaled Breath with Electronic Nose","publication_year":2022,"publication_date":"2022-05-29","ids":{"openalex":"https://openalex.org/W4281748688","doi":"https://doi.org/10.1109/isoen54820.2022.9789617"},"language":"en","primary_location":{"id":"doi:10.1109/isoen54820.2022.9789617","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isoen54820.2022.9789617","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064130079","display_name":"Yingying Xue","orcid":"https://orcid.org/0000-0002-9786-0183"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingying Xue","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102755586","display_name":"Yizhou Xiong","orcid":"https://orcid.org/0000-0002-2842-0002"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yizhou Xiong","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049447387","display_name":"Weijie Yu","orcid":"https://orcid.org/0000-0002-7773-6804"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijie Yu","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052515170","display_name":"Shimeng Mou","orcid":null},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shimeng Mou","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087599773","display_name":"Hao Wan","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Wan","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100338600","display_name":"Ping Wang","orcid":"https://orcid.org/0000-0001-6474-2722"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210098734","display_name":"Zhejiang Cancer Hospital","ror":"https://ror.org/0144s0951","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098734"]},{"id":"https://openalex.org/I4210107198","display_name":"State Key Laboratory of Transducer Technology","ror":"https://ror.org/01qg56n75","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210107198","https://openalex.org/I4210110458","https://openalex.org/I4210147322"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Wang","raw_affiliation_strings":["Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University,Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Hangzhou,China,310027","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Shanghai, China","institution_ids":["https://openalex.org/I4210107198","https://openalex.org/I19820366"]},{"raw_affiliation_string":"Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I4210098734","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0817,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.34877694,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"71","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10461","display_name":"Gas Sensing Nanomaterials and Sensors","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electronic-nose","display_name":"Electronic nose","score":0.8432408571243286},{"id":"https://openalex.org/keywords/breath-gas-analysis","display_name":"Breath gas analysis","score":0.7076586484909058},{"id":"https://openalex.org/keywords/periodontal-disease","display_name":"Periodontal disease","score":0.592926025390625},{"id":"https://openalex.org/keywords/nose","display_name":"Nose","score":0.5077741742134094},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.44131535291671753},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4205012917518616},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3199848532676697},{"id":"https://openalex.org/keywords/dentistry","display_name":"Dentistry","score":0.284211128950119},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2798033356666565},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.07908058166503906}],"concepts":[{"id":"https://openalex.org/C23895516","wikidata":"https://www.wikidata.org/wiki/Q550092","display_name":"Electronic nose","level":2,"score":0.8432408571243286},{"id":"https://openalex.org/C93353639","wikidata":"https://www.wikidata.org/wiki/Q754258","display_name":"Breath gas analysis","level":2,"score":0.7076586484909058},{"id":"https://openalex.org/C2992452445","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontal disease","level":2,"score":0.592926025390625},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.5077741742134094},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.44131535291671753},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4205012917518616},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3199848532676697},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.284211128950119},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2798033356666565},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.07908058166503906},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isoen54820.2022.9789617","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isoen54820.2022.9789617","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6200000047683716}],"awards":[{"id":"https://openalex.org/G1400432950","display_name":null,"funder_award_id":"62120106004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8336201900","display_name":null,"funder_award_id":"2021YFC3300303,2021YFB3200801","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1975412204","https://openalex.org/W2019825242","https://openalex.org/W2105580042","https://openalex.org/W2164653071","https://openalex.org/W2913824728","https://openalex.org/W3190301149"],"related_works":["https://openalex.org/W2056596841","https://openalex.org/W2349581046","https://openalex.org/W2080410076","https://openalex.org/W1982974357","https://openalex.org/W2245717424","https://openalex.org/W2991518432","https://openalex.org/W2969710556","https://openalex.org/W2036953109","https://openalex.org/W2883411385","https://openalex.org/W2162406816"],"abstract_inverted_index":{"Periodontal":[0],"diseases":[1],"seriously":[2],"affect":[3],"people's":[4],"physical":[5],"and":[6,53,107,115,152],"mental":[7],"health.":[8],"Electronic":[9],"noses":[10],"combined":[11,125],"with":[12,126,138],"intelligent":[13],"recognition":[14],"technology":[15],"have":[16,142],"been":[17],"widely":[18],"used":[19,148],"in":[20,26,135,150],"the":[21,27,35,66,74,99,102,110,120,127],"detection":[22,36,67],"of":[23,29,37,68,91,101,109],"exhaled":[24],"breath":[25,93],"diagnosis":[28],"diseases,":[30,140],"while":[31],"rarely":[32],"focused":[33],"on":[34,48],"periodontal":[38,69,84,139],"diseases.":[39,70],"In":[40,118],"this":[41],"study,":[42],"an":[43],"electronic":[44,75,122],"nose":[45,76,123],"system":[46,77,124],"based":[47],"electrochemical":[49],"sensors":[50],"was":[51,58],"developed":[52,121],"a":[54,61,132,143],"bionic":[55,129],"olfactory":[56,128],"model":[57,111,130],"constructed":[59],"using":[60],"spiking":[62],"neural":[63],"network":[64],"for":[65],"Results":[71],"show":[72],"that":[73],"can":[78],"accurately":[79],"identify":[80],"biomarkers":[81],"related":[82],"to":[83,97,146],"disease":[85],"(hydrogen":[86],"sulfide,":[87],"methanethiol).":[88],"A":[89],"total":[90],"27":[92],"samples":[94],"were":[95,112],"analyzed":[96],"verify":[98],"performance":[100,134],"model.":[103],"The":[104],"accuracy,":[105],"sensitivity,":[106],"specificity":[108],"88.9%,":[113],"81.3%,":[114],"100%,":[116],"respectively.":[117],"conclusion,":[119],"shows":[131],"high":[133],"identifying":[136],"patients":[137],"which":[141],"great":[144],"potential":[145],"be":[147],"both":[149],"clinical":[151],"point-of-care":[153],"testing.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}