{"id":"https://openalex.org/W2943692866","doi":"https://doi.org/10.1109/iscas.2019.8702817","title":"A Reprogrammable Low Power Closed-Loop Optogenetic Platform for Freely Moving Animals","display_name":"A Reprogrammable Low Power Closed-Loop Optogenetic Platform for Freely Moving Animals","publication_year":2019,"publication_date":"2019-05-01","ids":{"openalex":"https://openalex.org/W2943692866","doi":"https://doi.org/10.1109/iscas.2019.8702817","mag":"2943692866"},"language":"en","primary_location":{"id":"doi:10.1109/iscas.2019.8702817","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iscas.2019.8702817","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Symposium on Circuits and Systems (ISCAS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101778648","display_name":"Junwen Luo","orcid":"https://orcid.org/0000-0003-1007-7354"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jun-Wen Luo","raw_affiliation_strings":["School of Engineering, Newcastle University, Newcastle upon Tyne, UK"],"affiliations":[{"raw_affiliation_string":"School of Engineering, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045550469","display_name":"Andrew Jackson","orcid":"https://orcid.org/0000-0001-8701-6387"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Jackson","raw_affiliation_strings":["School of Engineering, Newcastle University, Newcastle upon Tyne, UK"],"affiliations":[{"raw_affiliation_string":"School of Engineering, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085160507","display_name":"Dimitris Firfilionis","orcid":null},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dimitris Firfilionis","raw_affiliation_strings":["School of Engineering, Newcastle University, Newcastle upon Tyne, UK"],"affiliations":[{"raw_affiliation_string":"School of Engineering, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021118449","display_name":"Patrick Degenaar","orcid":"https://orcid.org/0000-0002-5984-6698"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Patrick Degenaar","raw_affiliation_strings":["Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087371461","display_name":"Ahmed Soltan","orcid":"https://orcid.org/0000-0002-5153-3056"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ahmed Soltan","raw_affiliation_strings":["School of Engineering, Newcastle University, Newcastle upon Tyne, UK"],"affiliations":[{"raw_affiliation_string":"School of Engineering, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5101778648"],"corresponding_institution_ids":["https://openalex.org/I84884186"],"apc_list":null,"apc_paid":null,"fwci":0.1079,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.40951074,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/application-specific-integrated-circuit","display_name":"Application-specific integrated circuit","score":0.7038183212280273},{"id":"https://openalex.org/keywords/optogenetics","display_name":"Optogenetics","score":0.6955054998397827},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6534639000892639},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.5653172731399536},{"id":"https://openalex.org/keywords/flexibility","display_name":"Flexibility (engineering)","score":0.538700520992279},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.4482998251914978},{"id":"https://openalex.org/keywords/electronics","display_name":"Electronics","score":0.42060911655426025},{"id":"https://openalex.org/keywords/battery","display_name":"Battery (electricity)","score":0.41404253244400024},{"id":"https://openalex.org/keywords/power","display_name":"Power (physics)","score":0.40136995911598206},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.25459909439086914},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.22962340712547302}],"concepts":[{"id":"https://openalex.org/C77390884","wikidata":"https://www.wikidata.org/wiki/Q217302","display_name":"Application-specific integrated circuit","level":2,"score":0.7038183212280273},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.6955054998397827},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6534639000892639},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.5653172731399536},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.538700520992279},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.4482998251914978},{"id":"https://openalex.org/C138331895","wikidata":"https://www.wikidata.org/wiki/Q11650","display_name":"Electronics","level":2,"score":0.42060911655426025},{"id":"https://openalex.org/C555008776","wikidata":"https://www.wikidata.org/wiki/Q267298","display_name":"Battery (electricity)","level":3,"score":0.41404253244400024},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.40136995911598206},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.25459909439086914},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.22962340712547302},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iscas.2019.8702817","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iscas.2019.8702817","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Symposium on Circuits and Systems (ISCAS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Affordable and clean energy","score":0.8500000238418579,"id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W2056493740","https://openalex.org/W2067834276","https://openalex.org/W2126144964","https://openalex.org/W2470469249","https://openalex.org/W2513932403","https://openalex.org/W2563408576","https://openalex.org/W2736148182","https://openalex.org/W2754839168","https://openalex.org/W2782134926","https://openalex.org/W2805030207"],"related_works":["https://openalex.org/W4206570293","https://openalex.org/W3121604985","https://openalex.org/W3169838070","https://openalex.org/W3155801447","https://openalex.org/W1995267282","https://openalex.org/W4386305173","https://openalex.org/W2096235556","https://openalex.org/W4234016227","https://openalex.org/W2109867632","https://openalex.org/W4243806211"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3],"present":[4],"a":[5,35,94,102,108,117],"reprogrammable":[6],"low":[7],"power":[8,57,66,75],"optogenetic":[9],"based":[10,161],"platform":[11],"for":[12,40,143,156],"closed-loop":[13,110],"processing,":[14],"which":[15,71,123],"aims":[16],"on":[17],"neural":[18,136],"abnormal":[19,147],"activity":[20],"invention":[21],"such":[22,166],"as":[23,167],"epilepsy.":[24],"The":[25],"system":[26,79,95,126,139],"is":[27,52,113],"comprised":[28],"of":[29,77,146],"an":[30],"embedded":[31],"control":[32,160],"system,":[33],"and":[34,43,162],"custom":[36],"designed":[37],"ASIC":[38,90],"chip":[39],"electrical":[41],"recording":[42,85],"optical":[44],"stimulation.":[45],"Compared":[46],"to":[47,81,89,98,115],"current":[48],"technologies,":[49],"developed":[50,151],"technology":[51,152],"not":[53],"only":[54],"show":[55],"ultra-low":[56],"consumptions":[58],"but":[59],"also":[60],"displays":[61],"strong":[62],"computational":[63],"flexibility.":[64],"A":[65],"cycling":[67],"technique":[68],"was":[69],"implemented,":[70],"reduces":[72],"the":[73,78,125,141,150],"average":[74],"consumption":[76],"down":[80],"2.93":[82],"mA":[83],"at":[84],"frequency":[86],"50Hz":[87],"(equal":[88],"level).":[91],"This":[92],"allows":[93,124],"lifetime":[96],"up":[97],"56":[99],"hours":[100],"with":[101],"single":[103],"Lithium-Polymer":[104],"battery":[105],"(165mAh).":[106],"Then":[107],"three-stage":[109],"processing":[111],"scheme":[112],"employed":[114],"foster":[116],"Brain-machine":[118],"Interface":[119],"(BMI)":[120],"tool":[121],"box,":[122],"meets":[127],"various":[128],"biomedical":[129],"application":[130],"requirements.":[131],"By":[132],"using":[133],"in-vivo":[134],"epilepsy":[135],"data,":[137],"our":[138],"demonstrates":[140],"capability":[142],"realtime":[144],"intervention":[145],"activities.":[148],"Hence,":[149],"shows":[153],"great":[154],"potential":[155],"both":[157],"rodent":[158],"behavior":[159],"implantable":[163],"electronics":[164],"applications":[165],"chest":[168],"units.":[169]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}