{"id":"https://openalex.org/W2800082866","doi":"https://doi.org/10.1109/iscas.2018.8351719","title":"Reconfigurable Low-noise Multichannel Amplifier for Neurochemical Recording","display_name":"Reconfigurable Low-noise Multichannel Amplifier for Neurochemical Recording","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2800082866","doi":"https://doi.org/10.1109/iscas.2018.8351719","mag":"2800082866"},"language":"en","primary_location":{"id":"doi:10.1109/iscas.2018.8351719","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iscas.2018.8351719","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE International Symposium on Circuits and Systems (ISCAS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040448709","display_name":"Nishanth Kulasekeram","orcid":null},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nishanth Kulasekeram","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039130246","display_name":"Krzysztof Wildner","orcid":"https://orcid.org/0000-0003-0531-8563"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Krzysztof Wildner","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018680323","display_name":"Khalid B. Mirza","orcid":"https://orcid.org/0000-0001-8754-6468"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Khalid B. Mirza","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063863728","display_name":"Konstantin Nikoli\u0107","orcid":"https://orcid.org/0000-0002-6551-2977"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Konstantin Nikolic","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035891124","display_name":"C. Toumazou","orcid":"https://orcid.org/0000-0001-8773-7360"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christofer Toumazou","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5040448709"],"corresponding_institution_ids":["https://openalex.org/I47508984"],"apc_list":null,"apc_paid":null,"fwci":0.3269,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.55768545,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amplifier","display_name":"Amplifier","score":0.6877813339233398},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.5363295078277588},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5317826271057129},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.45983263850212097},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.44583770632743835},{"id":"https://openalex.org/keywords/low-noise-amplifier","display_name":"Low-noise amplifier","score":0.4377599060535431},{"id":"https://openalex.org/keywords/instrumentation-amplifier","display_name":"Instrumentation amplifier","score":0.4373071789741516},{"id":"https://openalex.org/keywords/operational-amplifier","display_name":"Operational amplifier","score":0.4323044419288635},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.25371092557907104}],"concepts":[{"id":"https://openalex.org/C194257627","wikidata":"https://www.wikidata.org/wiki/Q211554","display_name":"Amplifier","level":3,"score":0.6877813339233398},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.5363295078277588},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5317826271057129},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.45983263850212097},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.44583770632743835},{"id":"https://openalex.org/C155332784","wikidata":"https://www.wikidata.org/wiki/Q1151304","display_name":"Low-noise amplifier","level":4,"score":0.4377599060535431},{"id":"https://openalex.org/C89123640","wikidata":"https://www.wikidata.org/wiki/Q1523756","display_name":"Instrumentation amplifier","level":5,"score":0.4373071789741516},{"id":"https://openalex.org/C145366948","wikidata":"https://www.wikidata.org/wiki/Q178947","display_name":"Operational amplifier","level":4,"score":0.4323044419288635},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.25371092557907104}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iscas.2018.8351719","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iscas.2018.8351719","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE International Symposium on Circuits and Systems (ISCAS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7","score":0.7699999809265137}],"awards":[{"id":"https://openalex.org/G234491443","display_name":null,"funder_award_id":"EP/K009842/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6991775769","display_name":null,"funder_award_id":"EP/N002474/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1978223632","https://openalex.org/W2054043241","https://openalex.org/W2091665061","https://openalex.org/W2112929516","https://openalex.org/W2117901377","https://openalex.org/W2119652223","https://openalex.org/W2135388396","https://openalex.org/W2139426119","https://openalex.org/W2152963787","https://openalex.org/W2159318368","https://openalex.org/W2166535941","https://openalex.org/W2291728831","https://openalex.org/W2294437926","https://openalex.org/W2555109516","https://openalex.org/W2582798323","https://openalex.org/W2737660229","https://openalex.org/W4229689031","https://openalex.org/W6680218278"],"related_works":["https://openalex.org/W1595733580","https://openalex.org/W2011204264","https://openalex.org/W2381412985","https://openalex.org/W2566648942","https://openalex.org/W2744687610","https://openalex.org/W2501353045","https://openalex.org/W4234561568","https://openalex.org/W2965147246","https://openalex.org/W3199448205","https://openalex.org/W2165692906"],"abstract_inverted_index":{"An":[0],"integrated":[1,196],"circuit":[2,67,139,189,197],"for":[3,24,28,161,198,206],"real-time,":[4],"simultaneous":[5],"recording":[6,21,202],"of":[7,12,19,44,77,90,182,203],"electrical":[8,25,60,162],"and":[9,26,41,61,69,101,146,165],"chemical(pH)":[10],"signatures":[11],"neural":[13,163,204],"activity":[14,205],"is":[15,50,79],"presented.":[16],"It":[17],"consists":[18],"six":[20],"channels,":[22],"three":[23,27],"chemical":[29,62],"signals.":[30,173],"Each":[31,174],"channel":[32,175],"has":[33],"a":[34,39,53,71,155,166,199],"low-noise":[35],"amplifier":[36,78,150],"which":[37,86],"utilizes":[38],"new":[40],"optimized":[42],"technique":[43,122],"flicker":[45],"noise":[46,109,129],"suppression.":[47],"Our":[48],"approach":[49],"based":[51],"on":[52,112],"modified":[54],"switched":[55],"bias":[56,84],"current":[57],"technique.":[58],"Both":[59],"amplifiers":[63],"use":[64],"the":[65,75,83,88,91,113,177],"same":[66],"topology":[68],"have":[70,118],"common":[72],"footprint,":[73],"but":[74],"type":[76],"reconfigured":[80],"by":[81,131],"controlling":[82],"current,":[85],"controls":[87],"bandwidth":[89],"amplifier.":[92],"The":[93,149],"chip":[94,147],"was":[95,151],"fabricated":[96],"using":[97],"an":[98,133,142,180,195],"AMS":[99],"0.35\u03bcm":[100],"four":[102],"metal":[103],"double":[104],"poly":[105],"CMOS":[106],"technology.":[107],"Measured":[108],"reduction":[110],"depends":[111],"switching":[114,135],"frequency.":[115],"Bench":[116],"tests":[117],"shown":[119],"that":[120],"our":[121],"achieves":[123],"up":[124],"to":[125,153],"60%":[126],"intrinsic":[127],"1/f":[128],"suppression":[130],"determining":[132],"optimal":[134],"frequency,":[136],"without":[137],"additional":[138],"complexity":[140],"or":[141],"increase":[143],"in":[144],"transistor":[145],"area.":[148],"designed":[152],"exhibit":[154],"60":[156],"dB":[157,168],"closed":[158,169],"loop":[159,170],"gain":[160,171],"signals,":[164],"20":[167],"neurochemical":[172],"within":[176],"design":[178,190],"occupied":[179],"area":[181],"3.66mm":[183],"<sup":[184],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[185],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>":[186],".":[187],"This":[188],"will":[191],"be":[192],"used":[193],"as":[194],"real-time":[200],"bimodal":[201],"closed-loop":[207],"neuromodulation":[208],"therapies.":[209]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
