{"id":"https://openalex.org/W4410295694","doi":"https://doi.org/10.1109/isbi60581.2025.10980963","title":"Deep Learning-Driven Automated Aortic Valve Calcification Assessment in CT Calcium Score Screening Images","display_name":"Deep Learning-Driven Automated Aortic Valve Calcification Assessment in CT Calcium Score Screening Images","publication_year":2025,"publication_date":"2025-04-14","ids":{"openalex":"https://openalex.org/W4410295694","doi":"https://doi.org/10.1109/isbi60581.2025.10980963"},"language":"en","primary_location":{"id":"doi:10.1109/isbi60581.2025.10980963","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi60581.2025.10980963","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028294888","display_name":"Ananya Subramaniam","orcid":null},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ananya Subramaniam","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054938412","display_name":"Ammar Hoori","orcid":"https://orcid.org/0000-0002-8458-1214"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ammar Hoori","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066091502","display_name":"Tao Hu","orcid":"https://orcid.org/0009-0002-6661-2723"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao Hu","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083170497","display_name":"Hao Wu","orcid":"https://orcid.org/0000-0003-1269-7354"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hao Wu","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021561489","display_name":"Arthure Olivia Tchilibou Wane","orcid":null},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arthure Olivia Tchilibou Wane","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048842209","display_name":"Neda Shafiabadi Hassani","orcid":"https://orcid.org/0000-0001-8492-2683"},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neda Shafiabadi Hassani","raw_affiliation_strings":["Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022334933","display_name":"Sanjay Rajagopalan","orcid":"https://orcid.org/0000-0001-6669-8163"},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjay Rajagopalan","raw_affiliation_strings":["University Hospitals of Cleveland,Harrington Heart and Vascular Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospitals of Cleveland,Harrington Heart and Vascular Center","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059314323","display_name":"David L. Wilson","orcid":"https://orcid.org/0000-0001-9763-1463"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David L. Wilson","raw_affiliation_strings":["Case Western Reserve University,Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University,Department of Biomedical Engineering","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08378699,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9764000177383423,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9764000177383423,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10736","display_name":"Hydrogen embrittlement and corrosion behaviors in metals","score":0.9736999869346619,"subfield":{"id":"https://openalex.org/subfields/2506","display_name":"Metals and Alloys"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9670000076293945,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcification","display_name":"Calcification","score":0.6704555153846741},{"id":"https://openalex.org/keywords/aortic-valve","display_name":"Aortic valve","score":0.4866088628768921},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4603753685951233},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.42319542169570923},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.40761733055114746},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.39545220136642456},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3480314016342163},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.336678147315979},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.33646202087402344}],"concepts":[{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.6704555153846741},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.4866088628768921},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4603753685951233},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.42319542169570923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40761733055114746},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39545220136642456},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3480314016342163},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.336678147315979},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33646202087402344}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi60581.2025.10980963","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi60581.2025.10980963","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4099999964237213,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1575075233","https://openalex.org/W2108823687","https://openalex.org/W2464708700","https://openalex.org/W2661865952","https://openalex.org/W2751630023","https://openalex.org/W3115258265","https://openalex.org/W3127209854","https://openalex.org/W3195353558","https://openalex.org/W4211137352","https://openalex.org/W4281867324","https://openalex.org/W4311441990","https://openalex.org/W4380991841","https://openalex.org/W4388731864","https://openalex.org/W4393341617","https://openalex.org/W4401153181"],"related_works":["https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W2899084033","https://openalex.org/W1531601525","https://openalex.org/W2037906439","https://openalex.org/W2027697512","https://openalex.org/W2096216372","https://openalex.org/W2396995375","https://openalex.org/W992448008","https://openalex.org/W2142754305"],"abstract_inverted_index":{"Aortic":[0],"valve":[1,37,92,101,110,188],"stenosis":[2],"(AVS)":[3],"is":[4,40,66],"the":[5,11,22,57,144,148,192],"most":[6,13],"common":[7,14],"valvular":[8],"disease":[9],"and":[10,88,112,131,139],"third":[12],"cardiovascular":[15],"disease,":[16],"with":[17,45,169],"a":[18,41,67],"growing":[19],"impact":[20],"in":[21,27,185],"aging":[23],"population.":[24],"AVS":[25,85,196],"culminates":[26],"heart":[28,63],"failure":[29],"if":[30],"left":[31],"undiagnosed":[32],"or":[33],"untreated.":[34],"Transcatheter":[35],"aortic":[36,91,100,109,187],"replacement":[38],"(TAVR)":[39],"successful":[42],"interventional":[43],"procedure":[44],"reduced":[46],"risk":[47],"compared":[48],"to":[49,82,97,119],"surgical":[50],"alternatives.":[51],"As":[52],"early":[53,70,195],"intervention":[54],"may":[55],"reduce":[56],"number":[58],"of":[59,72,90,172],"patients":[60,126,146],"who":[61,127],"experience":[62],"failure,":[64],"there":[65],"need":[68],"for":[69,134,137,141,194],"detection":[71],"AVS.":[73],"CT":[74],"calcium":[75],"score":[76],"(CTCS)":[77],"exams":[78],"can":[79],"be":[80],"leveraged":[81],"opportunistically":[83],"detect":[84,99],"via":[86],"identification":[87],"evaluation":[89],"calcifications.":[93,121],"We":[94,122],"developed":[95],"methods":[96],"automatically":[98],"calcifications":[102],"from":[103,147,160],"CTCS":[104,129],"images":[105],"by":[106],"identifying":[107],"an":[108],"ROI":[111],"applying":[113],"clinically":[114],"approved":[115],"Agatston":[116,157,176],"(Ag)":[117],"criteria":[118],"obtain":[120],"retrospectively":[123],"collected":[124],"263":[125],"underwent":[128],"exams,":[130],"used":[132],"70%":[133],"training,":[135],"15%":[136,140],"validation,":[138],"testing.":[142],"Among":[143],"40":[145],"held-out":[149,173],"test":[150],"set,":[151],"we":[152],"had":[153],"82.5%":[154],"agreement":[155],"between":[156],"scores":[158],"calculated":[159],"manually":[161],"labeled":[162],"ground":[163],"truth":[164],"vs.":[165],"predicted":[166],"cylinder":[167],"masks,":[168],"only":[170],"5%":[171],"cases":[174],"having":[175],"differences":[177],"\u2265":[178],"200":[179],"Ag.":[180],"This":[181],"method":[182],"offers":[183],"promise":[184],"automated":[186],"calcification":[189],"identification,":[190],"paving":[191],"way":[193],"detection.":[197]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}