{"id":"https://openalex.org/W4401749864","doi":"https://doi.org/10.1109/isbi56570.2024.10635870","title":"Medisure: Towards Assuring Machine Learning-Based Medical Image Classifiers Using Mixup Boundary Analysis","display_name":"Medisure: Towards Assuring Machine Learning-Based Medical Image Classifiers Using Mixup Boundary Analysis","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401749864","doi":"https://doi.org/10.1109/isbi56570.2024.10635870"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635870","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635870","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093356365","display_name":"Adam Byfield","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Adam Byfield","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093356366","display_name":"William Poulett","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"William Poulett","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049734286","display_name":"Ben Wallace","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ben Wallace","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114211551","display_name":"Anusha Jose","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anusha Jose","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111296913","display_name":"Shatakshi Tyagi","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shatakshi Tyagi","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093356367","display_name":"Smita Shembekar","orcid":null},"institutions":[{"id":"https://openalex.org/I125671874","display_name":"National Health Service","ror":"https://ror.org/02wnqcb97","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I125671874","https://openalex.org/I1311074006"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Smita Shembekar","raw_affiliation_strings":["NHS England (National Health Service),UK","NHS England (National Health Service), UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NHS England (National Health Service),UK","institution_ids":["https://openalex.org/I125671874"]},{"raw_affiliation_string":"NHS England (National Health Service), UK","institution_ids":["https://openalex.org/I125671874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024012801","display_name":"Adnan Qayyum","orcid":"https://orcid.org/0000-0002-6732-7601"},"institutions":[{"id":"https://openalex.org/I1323252656","display_name":"Information Technology University","ror":"https://ror.org/00ngv8j44","country_code":"PK","type":"education","lineage":["https://openalex.org/I1323252656"]},{"id":"https://openalex.org/I172780181","display_name":"University of the Punjab","ror":"https://ror.org/011maz450","country_code":"PK","type":"education","lineage":["https://openalex.org/I172780181"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Adnan Qayyum","raw_affiliation_strings":["Information Technology University of the Punjab,Lahore,Pakistan","Information Technology University of the Punjab, Lahore, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Information Technology University of the Punjab,Lahore,Pakistan","institution_ids":["https://openalex.org/I172780181","https://openalex.org/I1323252656"]},{"raw_affiliation_string":"Information Technology University of the Punjab, Lahore, Pakistan","institution_ids":["https://openalex.org/I172780181","https://openalex.org/I1323252656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037574053","display_name":"Junaid Qadir","orcid":"https://orcid.org/0000-0001-9466-2475"},"institutions":[{"id":"https://openalex.org/I60342839","display_name":"Qatar University","ror":"https://ror.org/00yhnba62","country_code":"QA","type":"education","lineage":["https://openalex.org/I60342839"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Junaid Qadir","raw_affiliation_strings":["Qatar University,Doha,Qatar","Qatar University, Doha, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qatar University,Doha,Qatar","institution_ids":["https://openalex.org/I60342839"]},{"raw_affiliation_string":"Qatar University, Doha, Qatar","institution_ids":["https://openalex.org/I60342839"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111005051","display_name":"Muhammad Bilal","orcid":"https://orcid.org/0000-0002-3823-3905"},"institutions":[{"id":"https://openalex.org/I12870472","display_name":"Birmingham City University","ror":"https://ror.org/00t67pt25","country_code":"GB","type":"education","lineage":["https://openalex.org/I12870472"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Muhammad Bilal","raw_affiliation_strings":["Birmingham City University (BCU),Birmingham,UK","Birmingham City University (BCU), Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Birmingham City University (BCU),Birmingham,UK","institution_ids":["https://openalex.org/I12870472"]},{"raw_affiliation_string":"Birmingham City University (BCU), Birmingham, UK","institution_ids":["https://openalex.org/I12870472"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10850878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.755259096622467},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5721808075904846},{"id":"https://openalex.org/keywords/boundary","display_name":"Boundary (topology)","score":0.5494633316993713},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5120266079902649},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.49117371439933777},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.39354071021080017},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.08512628078460693}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.755259096622467},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5721808075904846},{"id":"https://openalex.org/C62354387","wikidata":"https://www.wikidata.org/wiki/Q875399","display_name":"Boundary (topology)","level":2,"score":0.5494633316993713},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5120266079902649},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.49117371439933777},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.39354071021080017},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08512628078460693},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635870","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635870","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:www.open-access.bcu.ac.uk:15560","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402654","display_name":"BCU Open Access Repository (Birmingham City University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I12870472","host_organization_name":"Birmingham City University","host_organization_lineage":["https://openalex.org/I12870472"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"pmh:oai:qspace.qu.edu.qa:10576/66054","is_oa":false,"landing_page_url":"http://hdl.handle.net/10576/66054","pdf_url":null,"source":{"id":"https://openalex.org/S4306400014","display_name":"Qatar University QSpace (Qatar University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60342839","host_organization_name":"Qatar University","host_organization_lineage":["https://openalex.org/I60342839"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W3004684240","https://openalex.org/W3010293082","https://openalex.org/W3046918297","https://openalex.org/W3096759520","https://openalex.org/W3163960008","https://openalex.org/W3209901185","https://openalex.org/W4220891756","https://openalex.org/W4223506650","https://openalex.org/W4307823382","https://openalex.org/W4312921627","https://openalex.org/W6773493696"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W2772917594","https://openalex.org/W2036807459","https://openalex.org/W2058170566","https://openalex.org/W2755342338","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407"],"abstract_inverted_index":{"Machine":[0],"learning":[1],"(ML)":[2],"models":[3,24,95],"are":[4,25,50],"becoming":[5],"integral":[6],"in":[7,40,96,115],"healthcare":[8,156],"technologies,":[9],"necessitating":[10],"formal":[11],"assurance":[12,44,76,143],"methods":[13],"to":[14,30,54,72,145],"ensure":[15],"their":[16],"safety,":[17],"fairness,":[18],"robustness,":[19],"and":[20,33,59,89,126,131,153],"trustworthiness.":[21],"However,":[22],"these":[23],"inherently":[26],"error-prone,":[27],"posing":[28],"risks":[29],"patient":[31],"health":[32],"potentially":[34],"causing":[35],"irreparable":[36],"harm":[37],"when":[38],"deployed":[39],"clinics.":[41],"Traditional":[42],"software":[43,75],"techniques,":[45],"designed":[46],"for":[47],"fixed":[48],"code,":[49],"not":[51],"directly":[52],"applicable":[53],"ML":[55,94,147],"models,":[56,148],"which":[57],"adapt":[58,73],"learn":[60],"from":[61],"curated":[62],"datasets":[63],"during":[64],"training.":[65],"Thus,":[66],"there":[67],"is":[68,160],"an":[69],"urgent":[70],"need":[71],"established":[74],"principles":[77,144],"such":[78],"as":[79],"boundary":[80],"testing":[81],"with":[82],"synthetic":[83],"data.":[84],"To":[85],"bridge":[86],"this":[87],"gap":[88],"enable":[90],"objective":[91],"assessment":[92],"of":[93,112,117,140,155],"real-world":[97],"clinical":[98],"settings,":[99],"we":[100],"propose":[101],"Mix-Up":[102],"Boundary":[103],"Analysis":[104],"(MUBA),":[105],"a":[106],"novel":[107],"technique":[108],"facilitating":[109],"the":[110,138,151],"evaluation":[111],"image":[113],"classifiers":[114],"terms":[116],"prediction":[118],"fairness.":[119],"We":[120],"evaluated":[121],"MUBA":[122],"using":[123],"brain":[124],"tumour":[125],"breast":[127],"cancer":[128],"classification":[129],"tasks":[130],"achieved":[132],"promising":[133],"results.":[134],"This":[135],"research":[136],"underscores":[137],"importance":[139],"adapting":[141],"traditional":[142],"assess":[146],"ultimately":[149],"enhancing":[150],"safety":[152],"reliability":[154],"technologies.":[157],"Our":[158],"code":[159],"available":[161],"at":[162],"https:":[163],"//github.com/willpoulett/MUBA_pipeline.":[164]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}