{"id":"https://openalex.org/W4401750703","doi":"https://doi.org/10.1109/isbi56570.2024.10635651","title":"Unsupervised Airway Tree Clustering with Deep Learning: the Multi-Ethnic Study of Atherosclerosis (Mesa) Lung Study","display_name":"Unsupervised Airway Tree Clustering with Deep Learning: the Multi-Ethnic Study of Atherosclerosis (Mesa) Lung Study","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401750703","doi":"https://doi.org/10.1109/isbi56570.2024.10635651","pmid":"https://pubmed.ncbi.nlm.nih.gov/39398280"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635651","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635651","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["arxiv","crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2402.18615","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021855671","display_name":"Sneha N. Naik","orcid":"https://orcid.org/0000-0002-9949-0024"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sneha N. Naik","raw_affiliation_strings":["Columbia University,USA"],"affiliations":[{"raw_affiliation_string":"Columbia University,USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008972669","display_name":"Elsa D. Angelini","orcid":"https://orcid.org/0000-0002-1602-300X"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elsa D. Angelini","raw_affiliation_strings":["Columbia University,USA"],"affiliations":[{"raw_affiliation_string":"Columbia University,USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070233463","display_name":"R. Graham Barr","orcid":"https://orcid.org/0000-0001-8021-0072"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Graham Barr","raw_affiliation_strings":["Columbia University,USA"],"affiliations":[{"raw_affiliation_string":"Columbia University,USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028606685","display_name":"Norrina B. Allen","orcid":"https://orcid.org/0000-0002-6993-4384"},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norrina Allen","raw_affiliation_strings":["Northwestern University,USA"],"affiliations":[{"raw_affiliation_string":"Northwestern University,USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005312014","display_name":"Alain G. Bertoni","orcid":"https://orcid.org/0000-0002-7503-6273"},"institutions":[{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alain Bertoni","raw_affiliation_strings":["Wake Forest University,USA"],"affiliations":[{"raw_affiliation_string":"Wake Forest University,USA","institution_ids":["https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011527598","display_name":"Eric A. Hoffman","orcid":"https://orcid.org/0000-0001-8456-9437"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric A. Hoffman","raw_affiliation_strings":["University of Iowa,USA"],"affiliations":[{"raw_affiliation_string":"University of Iowa,USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029044079","display_name":"Ani Manichaikul","orcid":"https://orcid.org/0000-0002-5998-795X"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ani Manichaikul","raw_affiliation_strings":["University of Virginia,USA"],"affiliations":[{"raw_affiliation_string":"University of Virginia,USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022683360","display_name":"James S. Pankow","orcid":"https://orcid.org/0000-0001-7076-483X"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jim Pankow","raw_affiliation_strings":["University of Minnesota,USA"],"affiliations":[{"raw_affiliation_string":"University of Minnesota,USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047340885","display_name":"Wendy S. Post","orcid":"https://orcid.org/0000-0002-8655-5204"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wendy Post","raw_affiliation_strings":["Johns Hopkins University,USA"],"affiliations":[{"raw_affiliation_string":"Johns Hopkins University,USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078704429","display_name":"Yifei Sun","orcid":"https://orcid.org/0000-0002-6961-5500"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yifei Sun","raw_affiliation_strings":["Columbia University,USA"],"affiliations":[{"raw_affiliation_string":"Columbia University,USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050298082","display_name":"Karol Watson","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karol Watson","raw_affiliation_strings":["University of California,USA"],"affiliations":[{"raw_affiliation_string":"University of California,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043154534","display_name":"Benjamin M. Smith","orcid":"https://orcid.org/0000-0002-0619-5799"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Benjamin M. Smith","raw_affiliation_strings":["McGill University,Canada"],"affiliations":[{"raw_affiliation_string":"McGill University,Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090489079","display_name":"Andrew F. Laine","orcid":"https://orcid.org/0000-0003-3797-0628"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew F. Laine","raw_affiliation_strings":["Columbia University,USA"],"affiliations":[{"raw_affiliation_string":"Columbia University,USA","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5021855671"],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":null,"apc_paid":null,"fwci":0.4081,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.65805346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9783999919891357,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12419","display_name":"Phonocardiography and Auscultation Techniques","score":0.9508000016212463,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesa","display_name":"Mesa","score":0.9168983697891235},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.5668569803237915},{"id":"https://openalex.org/keywords/unsupervised-learning","display_name":"Unsupervised learning","score":0.5647373795509338},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5509870052337646},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5383883714675903},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.4912652373313904},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.487984836101532},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3362399637699127},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19064658880233765}],"concepts":[{"id":"https://openalex.org/C2780940541","wikidata":"https://www.wikidata.org/wiki/Q1042397","display_name":"Mesa","level":2,"score":0.9168983697891235},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.5668569803237915},{"id":"https://openalex.org/C8038995","wikidata":"https://www.wikidata.org/wiki/Q1152135","display_name":"Unsupervised learning","level":2,"score":0.5647373795509338},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5509870052337646},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5383883714675903},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.4912652373313904},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.487984836101532},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3362399637699127},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19064658880233765},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635651","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635651","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:39398280","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39398280","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:arXiv.org:2402.18615","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2402.18615","pdf_url":"https://arxiv.org/pdf/2402.18615","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:11467912","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11467912","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11467912/pdf/nihms-2027023.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},{"id":"doi:10.48550/arxiv.2402.18615","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2402.18615","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2402.18615","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2402.18615","pdf_url":"https://arxiv.org/pdf/2402.18615","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1269631540","display_name":null,"funder_award_id":"75N92020D00005","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1276754516","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1294553593","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G1412221515","display_name":null,"funder_award_id":"75N92020D00003","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1539384734","display_name":null,"funder_award_id":"75N92020D00001","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1657168240","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1803853571","display_name":null,"funder_award_id":"75N92020D00006","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1877939937","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1956357178","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1969827686","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1983464145","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2095942735","display_name":null,"funder_award_id":"UL1-TR","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2125623581","display_name":null,"funder_award_id":"R01-HL093081","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2238490387","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2295196357","display_name":null,"funder_award_id":"00003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2432076436","display_name":null,"funder_award_id":"5N92020D00005","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2580996367","display_name":null,"funder_award_id":"75N92020D00007","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2623405628","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2639998763","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2726417417","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2750540916","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2789588635","display_name":null,"funder_award_id":"NCATS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2832476122","display_name":null,"funder_award_id":"N01-HC-9516","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3259655001","display_name":null,"funder_award_id":"HSN268201500003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3359243492","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3570589137","display_name":null,"funder_award_id":"75N92020D00002","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3575057044","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3595232572","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G3676546685","display_name":null,"funder_award_id":"75N92020D00006","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3826568287","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3982441736","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3983070977","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4043617354","display_name":null,"funder_award_id":"HL093081","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4101536646","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4146420730","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4266184307","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4309390892","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4405402368","display_name":null,"funder_award_id":"R01-HL093081","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4563812999","display_name":null,"funder_award_id":"75N92020D00005","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4590187187","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4842175797","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G486305083","display_name":null,"funder_award_id":"R01-HL093081","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4986157935","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5075046117","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5138253846","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G514410172","display_name":null,"funder_award_id":"75N92020D00003","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G535872069","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5418415654","display_name":null,"funder_award_id":"5N92020D00001","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5439146981","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5493479587","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5653954166","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G575289800","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6336628147","display_name":null,"funder_award_id":"00002","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6345853531","display_name":null,"funder_award_id":"unknown","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6742279884","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6789189252","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6798586005","display_name":null,"funder_award_id":"75N92020D00004","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6855506055","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6856766826","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G6916991146","display_name":null,"funder_award_id":"R01 HL155816","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6951716892","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7062576961","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7166352866","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G7462069030","display_name":null,"funder_award_id":"75N92020D00007","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7525493423","display_name":null,"funder_award_id":"R01-HL130506","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7610800535","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7811600844","display_name":null,"funder_award_id":"R01-HL130506","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7826153973","display_name":null,"funder_award_id":"75N92020D00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7886706545","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G797182136","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G8068815734","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8145863542","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G8198795195","display_name":null,"funder_award_id":"00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8245670873","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8288036582","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G842756795","display_name":null,"funder_award_id":"75N92020D00002","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8714546325","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8761005068","display_name":null,"funder_award_id":"75N92020D00004","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8810606248","display_name":null,"funder_award_id":"HHSN268201500003","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8852914737","display_name":null,"funder_award_id":"UL1-TR-","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401750703.pdf"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1608072211","https://openalex.org/W1901129140","https://openalex.org/W1966119405","https://openalex.org/W2037315561","https://openalex.org/W2037810426","https://openalex.org/W2120397327","https://openalex.org/W2156097706","https://openalex.org/W2172012864","https://openalex.org/W2524508118","https://openalex.org/W2783379777","https://openalex.org/W2892492415","https://openalex.org/W3033045524","https://openalex.org/W3047298397","https://openalex.org/W3091943745","https://openalex.org/W3165525854","https://openalex.org/W3190742591","https://openalex.org/W4210681352","https://openalex.org/W4379015825","https://openalex.org/W4386575214"],"related_works":["https://openalex.org/W2519447379","https://openalex.org/W13437552","https://openalex.org/W3208464130","https://openalex.org/W3191292493","https://openalex.org/W3190847661","https://openalex.org/W1531192254","https://openalex.org/W1550375662","https://openalex.org/W2919383900","https://openalex.org/W4220926404","https://openalex.org/W3123344745"],"abstract_inverted_index":{"High-resolution":[0],"full":[1],"lung":[2],"CT":[3,88,145],"scans":[4],"now":[5],"enable":[6],"the":[7,15,64,99,142],"detailed":[8],"segmentation":[9],"of":[10,63,84,98,104,120,128],"airway":[11,20,66,90,122,130,139],"trees":[12],"up":[13],"to":[14,34,41],"6th":[16],"branching":[17],"generation.":[18],"The":[19],"binary":[21],"masks":[22],"display":[23],"very":[24],"complex":[25],"tree":[26,67,91],"structures":[27],"that":[28,55],"may":[29],"encode":[30],"biological":[31],"information":[32],"relevant":[33],"disease":[35],"risk":[36],"and":[37,61,78,101,118,136],"yet":[38],"remain":[39,92],"challenging":[40],"exploit":[42],"via":[43],"traditional":[44],"methods":[45],"such":[46],"as":[47,94],"meshing":[48],"or":[49],"skeletonization.":[50],"Recent":[51],"clinical":[52,100],"studies":[53],"suggest":[54],"some":[56],"variations":[57,85],"in":[58,141],"shape":[59],"patterns":[60],"caliber":[62],"human":[65,121],"are":[68],"highly":[69],"associated":[70],"with":[71],"adverse":[72],"health":[73],"outcomes,":[74],"including":[75],"all-cause":[76],"mortality":[77],"incident":[79],"COPD.":[80],"However,":[81],"quantitative":[82],"characterization":[83],"observed":[86],"on":[87],"segmented":[89],"incomplete,":[93],"does":[95],"our":[96],"understanding":[97],"developmental":[102],"implications":[103],"such.":[105],"In":[106],"this":[107],"work,":[108],"we":[109],"present":[110],"an":[111],"unsupervised":[112],"deep-learning":[113],"pipeline":[114],"for":[115],"feature":[116],"extraction":[117],"clustering":[119],"trees,":[123],"learned":[124],"directly":[125],"from":[126],"projections":[127],"3D":[129],"segmentations.":[131],"We":[132],"identify":[133],"four":[134],"reproducible":[135],"clinically":[137],"distinct":[138],"sub-types":[140],"MESA":[143],"Lung":[144],"cohort.":[146]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-12T07:58:50.170612","created_date":"2025-10-10T00:00:00"}