{"id":"https://openalex.org/W4401748830","doi":"https://doi.org/10.1109/isbi56570.2024.10635567","title":"Image Synthesis of Hepatobiliary Phase using Contrast-Enhanced MRI and Diffusion Model","display_name":"Image Synthesis of Hepatobiliary Phase using Contrast-Enhanced MRI and Diffusion Model","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401748830","doi":"https://doi.org/10.1109/isbi56570.2024.10635567"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635567","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi56570.2024.10635567","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048473504","display_name":"Shangxuan Li","orcid":"https://orcid.org/0009-0006-0896-288X"},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shangxuan Li","raw_affiliation_strings":["Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026558230","display_name":"Baoer Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baoer Liu","raw_affiliation_strings":["Southern Medical University,Department of Medical Imaging Center, Nanfang Hospital,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Southern Medical University,Department of Medical Imaging Center, Nanfang Hospital,China","institution_ids":["https://openalex.org/I58200834","https://openalex.org/I4210103346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114211581","display_name":"Feilin Deng","orcid":null},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feilin Deng","raw_affiliation_strings":["Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111290361","display_name":"Yikai Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yikai Xu","raw_affiliation_strings":["Southern Medical University,Department of Medical Imaging Center, Nanfang Hospital,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Southern Medical University,Department of Medical Imaging Center, Nanfang Hospital,China","institution_ids":["https://openalex.org/I58200834","https://openalex.org/I4210103346"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103039481","display_name":"Zhou Wu","orcid":"https://orcid.org/0000-0002-1211-334X"},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wu Zhou","raw_affiliation_strings":["Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangzhou University of Chinese Medicine,School of Medical Information Engineering,China","institution_ids":["https://openalex.org/I117532281"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.22071239,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"abs/2006.11239","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9739000201225281,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9739000201225281,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.972100019454956,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9559999704360962,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contrast","display_name":"Contrast (vision)","score":0.5880669355392456},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.561917781829834},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5280723571777344},{"id":"https://openalex.org/keywords/phase","display_name":"Phase (matter)","score":0.4827953577041626},{"id":"https://openalex.org/keywords/phase-contrast-microscopy","display_name":"Phase contrast microscopy","score":0.4819647967815399},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.4150509834289551},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.393787682056427},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3671993613243103},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3618339002132416},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3437705934047699},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.303053617477417},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2211655080318451},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2089959979057312},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.1611471176147461},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16099074482917786}],"concepts":[{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.5880669355392456},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.561917781829834},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5280723571777344},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.4827953577041626},{"id":"https://openalex.org/C151193507","wikidata":"https://www.wikidata.org/wiki/Q898815","display_name":"Phase contrast microscopy","level":2,"score":0.4819647967815399},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.4150509834289551},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.393787682056427},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3671993613243103},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3618339002132416},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3437705934047699},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.303053617477417},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2211655080318451},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2089959979057312},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1611471176147461},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16099074482917786},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635567","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi56570.2024.10635567","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2011193325","https://openalex.org/W2023116210","https://openalex.org/W2058174138","https://openalex.org/W2486210662","https://openalex.org/W2785800998","https://openalex.org/W3007486523","https://openalex.org/W3018177167","https://openalex.org/W3036167779","https://openalex.org/W3131055003","https://openalex.org/W3132541979","https://openalex.org/W4214497062","https://openalex.org/W4220945685","https://openalex.org/W4312933868","https://openalex.org/W4379660313","https://openalex.org/W6847338848"],"related_works":["https://openalex.org/W2069592018","https://openalex.org/W2075740387","https://openalex.org/W2358990940","https://openalex.org/W2093931120","https://openalex.org/W2329812990","https://openalex.org/W1768769760","https://openalex.org/W2413360119","https://openalex.org/W2349116365","https://openalex.org/W186269150","https://openalex.org/W2081487848"],"abstract_inverted_index":{"Hepatobiliary":[0],"phase":[1],"(HBP)":[2],"imaging":[3,16],"is":[4,20,166],"of":[5,11,18,33,121,151,157,183,193,196,202],"great":[6],"value":[7],"in":[8,46,140],"the":[9,15,31,75,141,145,155,158,163,169,176,181,184,191,200],"diagnosis":[10],"liver":[12],"cancer.":[13],"However,":[14],"process":[17],"HBP":[19,40,63,81,203],"very":[21],"time-consuming,":[22],"and":[23,44,68,86,137],"it":[24,206],"needs":[25],"to":[26,38,99,117,134,168,199],"wait":[27],"20":[28],"minutes":[29],"after":[30],"injection":[32],"contrast":[34],"agent.":[35],"In":[36,115,174],"order":[37,116],"obtain":[39],"images":[41,64,67,82],"more":[42],"conveniently":[43],"efficiently":[45],"clinic,":[47],"we":[48,129,188],"propose":[49,130],"a":[50,107,131],"novel":[51],"method":[52,165],"based":[53],"on":[54,101],"multimodal":[55,104],"image":[56,171],"synthesis":[57,172],"with":[58],"deep":[59],"learning,":[60],"which":[61],"generates":[62],"through":[65,90,106],"contrast-enhanced":[66,122,197],"diffusion":[69,77,95,142],"models.":[70],"We":[71],"first":[72],"independently":[73],"train":[74],"late":[76],"models":[78,96],"for":[79,83,208],"generating":[80],"each":[84],"modality,":[85],"pre-align":[87],"all":[88],"encoders":[89],"contrastive":[91],"learning.":[92],"Then,":[93],"these":[94],"effectively":[97],"learn":[98],"focus":[100],"cross-modal":[102],"joint":[103,146],"generation":[105,127,147,201],"transformer":[108],"mechanism":[109],"called":[110],"\"latent":[111],"spatiotemporal":[112,119,132],"alignment\"":[113],"(LSAT).":[114],"model":[118],"characteristics":[120],"MR":[123,198],"while":[124],"maintaining":[125],"visual":[126],"quality,":[128],"module":[133],"construct":[135],"diffusers":[136],"achieve":[138],"cross-attention":[139],"stream":[143],"during":[144],"process.":[148],"The":[149],"results":[150],"clinical":[152,209],"experiments":[153],"demonstrate":[154],"effectiveness":[156,182],"proposed":[159,164,185],"method,":[160],"indicating":[161],"that":[162],"superior":[167],"typical":[170],"methods.":[173],"addition,":[175],"ablation":[177],"study":[178],"also":[179],"demonstrates":[180],"modules.":[186],"Finally,":[187],"quantitatively":[189],"reveal":[190],"contribution":[192],"different":[194],"modalities":[195],"images,":[204],"making":[205],"easier":[207],"interpretability.":[210]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}