{"id":"https://openalex.org/W4401749536","doi":"https://doi.org/10.1109/isbi56570.2024.10635503","title":"Self-Supervised Learning for Genetically Relevant Domain Identification in Morphological Images","display_name":"Self-Supervised Learning for Genetically Relevant Domain Identification in Morphological Images","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401749536","doi":"https://doi.org/10.1109/isbi56570.2024.10635503"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635503","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi56570.2024.10635503","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085918736","display_name":"Eduard Chelebian","orcid":"https://orcid.org/0000-0001-6852-6605"},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I4210158519","display_name":"Informa (Sweden)","ror":"https://ror.org/04yt64d76","country_code":"SE","type":"company","lineage":["https://openalex.org/I4210154378","https://openalex.org/I4210158519"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Eduard Chelebian","raw_affiliation_strings":["Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden"],"affiliations":[{"raw_affiliation_string":"Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I4210158519","https://openalex.org/I2800139495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003593517","display_name":"Christophe Avenel","orcid":"https://orcid.org/0000-0002-1835-921X"},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I4210158519","display_name":"Informa (Sweden)","ror":"https://ror.org/04yt64d76","country_code":"SE","type":"company","lineage":["https://openalex.org/I4210154378","https://openalex.org/I4210158519"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christophe Avenel","raw_affiliation_strings":["Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden"],"affiliations":[{"raw_affiliation_string":"Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I4210158519","https://openalex.org/I2800139495"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028372092","display_name":"Carolina W\u00e4hlby","orcid":"https://orcid.org/0000-0002-4139-7003"},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I4210158519","display_name":"Informa (Sweden)","ror":"https://ror.org/04yt64d76","country_code":"SE","type":"company","lineage":["https://openalex.org/I4210154378","https://openalex.org/I4210158519"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carolina W\u00e4hlby","raw_affiliation_strings":["Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden"],"affiliations":[{"raw_affiliation_string":"Uppsala University,Department of Information Technology and SciLifeLab,Uppsala,Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I4210158519","https://openalex.org/I2800139495"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5085918736"],"corresponding_institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495","https://openalex.org/I4210158519"],"apc_list":null,"apc_paid":null,"fwci":0.2624,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.52346971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.982200026512146,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.982200026512146,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10627","display_name":"Advanced Image and Video Retrieval Techniques","score":0.9632999897003174,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10689","display_name":"Remote-Sensing Image Classification","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6422333121299744},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6385445594787598},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.613763689994812},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.5204135179519653},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.44623643159866333},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14844581484794617},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.11241957545280457}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6422333121299744},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6385445594787598},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.613763689994812},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5204135179519653},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.44623643159866333},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14844581484794617},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11241957545280457},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635503","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi56570.2024.10635503","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1984689597","https://openalex.org/W2124386111","https://openalex.org/W2194775991","https://openalex.org/W2994000519","https://openalex.org/W3027278249","https://openalex.org/W3032266082","https://openalex.org/W3108118546","https://openalex.org/W3204251661","https://openalex.org/W3212889265","https://openalex.org/W4206826076","https://openalex.org/W4235169531","https://openalex.org/W4281618613","https://openalex.org/W4303438684","https://openalex.org/W4304730933","https://openalex.org/W4313156423","https://openalex.org/W4385515928","https://openalex.org/W6774314701"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W3046775127","https://openalex.org/W3107602296","https://openalex.org/W4394896187","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W4364306694","https://openalex.org/W4312192474","https://openalex.org/W4283697347"],"abstract_inverted_index":{"Spatial-omics":[0],"techniques":[1],"are":[2],"used":[3,17],"for":[4,18,94,114,122],"profiling":[5],"the":[6,20,26,30,101,109],"local":[7],"gene":[8,27,49],"expression":[9,50],"of":[10,66,73,112],"a":[11],"sample,":[12],"while":[13],"imaging":[14,69],"is":[15,91,127],"typically":[16],"capturing":[19,95],"phenotype,":[21],"in":[22,56],"turn":[23],"determined":[24],"by":[25],"expression.":[28],"However,":[29],"correlation":[31],"between":[32],"them":[33],"may":[34,51],"not":[35,52,128],"necessarily":[36],"be":[37],"direct.":[38],"Tissue":[39],"morphology":[40],"can":[41],"also":[42,121],"reflect":[43],"genes":[44],"expressed":[45],"during":[46],"development,":[47],"or":[48],"yet":[53],"have":[54,62],"resulted":[55],"tissue":[57,97],"restructuring.":[58],"Thus,":[59],"recent":[60],"efforts":[61],"shown":[63],"that":[64,81],"integration":[65,120],"spatial-omics":[67],"with":[68,100],"provides":[70],"additional":[71],"information":[72],"biological":[74],"relevance.":[75],"In":[76],"this":[77],"work,":[78],"we":[79],"show":[80],"morphological":[82,119],"feature":[83],"extraction":[84],"on":[85],"H&E":[86,125],"images":[87],"using":[88],"self-supervised":[89,106],"learning":[90,107],"more":[92],"versatile":[93],"relevant":[96],"domains":[98],"compared":[99],"previously":[102],"proposed":[103],"approaches.":[104],"Furthermore,":[105],"allows":[108],"novel":[110],"use":[111],"DAPI":[113],"domain":[115],"identification,":[116],"which":[117],"enables":[118],"experiments":[123],"where":[124],"staining":[126],"available.":[129]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-12-26T23:08:49.675405","created_date":"2025-10-10T00:00:00"}
