{"id":"https://openalex.org/W4401751879","doi":"https://doi.org/10.1109/isbi56570.2024.10635469","title":"Enhancing Generalizability in Brain Tumor Segmentation: Model Ensemble with Adaptive Post-Processing","display_name":"Enhancing Generalizability in Brain Tumor Segmentation: Model Ensemble with Adaptive Post-Processing","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401751879","doi":"https://doi.org/10.1109/isbi56570.2024.10635469","pmid":"https://pubmed.ncbi.nlm.nih.gov/41404440"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635469","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635469","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12704145/pdf/nihms-2119394.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068633300","display_name":"Zhifan Jiang","orcid":"https://orcid.org/0000-0001-5713-1675"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhifan Jiang","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020437693","display_name":"Daniel Capell\u00e1n-Mart\u00edn","orcid":"https://orcid.org/0000-0002-9743-0845"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Capell\u00e1n-Mart\u00edn","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089319608","display_name":"Abhijeet Parida","orcid":"https://orcid.org/0000-0002-4978-0576"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abhijeet Parida","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100625902","display_name":"Xinyang Liu","orcid":"https://orcid.org/0000-0002-5827-7729"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinyang Liu","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012910949","display_name":"Mar\u00eda J. Ledesma\u2010Carbayo","orcid":"https://orcid.org/0000-0001-6846-3923"},"institutions":[{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda J. Ledesma-Carbayo","raw_affiliation_strings":["Universidad Politécnica de Madrid & CIBER-BBN,Biomedical Image Technologies, ETSI Telecomunicación,Madrid,Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad Politécnica de Madrid & CIBER-BBN,Biomedical Image Technologies, ETSI Telecomunicación,Madrid,Spain","institution_ids":["https://openalex.org/I4210105141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073762312","display_name":"Syed Muhammad Anwar","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Syed Muhammad Anwar","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085732379","display_name":"Marius George Linguraru","orcid":"https://orcid.org/0000-0001-6175-8665"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marius George Linguraru","raw_affiliation_strings":["Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children’s National Hospital,Sheikh Zayed Institute for Pediatric Surgical Innovation,Washington,DC,USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4299,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.63526801,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9347000122070312,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generalizability-theory","display_name":"Generalizability theory","score":0.906306266784668},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.676662027835846},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5467660427093506},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5394694209098816},{"id":"https://openalex.org/keywords/natural-language-processing","display_name":"Natural language processing","score":0.3257218301296234},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.17448580265045166}],"concepts":[{"id":"https://openalex.org/C27158222","wikidata":"https://www.wikidata.org/wiki/Q5532422","display_name":"Generalizability theory","level":2,"score":0.906306266784668},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.676662027835846},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5467660427093506},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5394694209098816},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.3257218301296234},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.17448580265045166},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635469","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635469","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:41404440","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41404440","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12704145","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12704145/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12704145/pdf/nihms-2119394.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12704145","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12704145/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12704145/pdf/nihms-2119394.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2085528529","display_name":null,"funder_award_id":"PDC2022","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G7770515289","display_name":null,"funder_award_id":"101100633","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7997405460","display_name":null,"funder_award_id":"PDC2022-133865-I00","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G8920660035","display_name":null,"funder_award_id":"PID2022","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322138","display_name":"Universidad Polit\u00e9cnica de Madrid","ror":"https://ror.org/03n6nwv02"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320335598","display_name":"Agencia Estatal de Investigaci\u00f3n","ror":null},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401751879.pdf"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1641498739","https://openalex.org/W1901129140","https://openalex.org/W2106235379","https://openalex.org/W2767128594","https://openalex.org/W2963046541","https://openalex.org/W3014974815","https://openalex.org/W3094502228","https://openalex.org/W3112701542","https://openalex.org/W4212875960","https://openalex.org/W4221163766","https://openalex.org/W4327574677","https://openalex.org/W4376988550","https://openalex.org/W4379087043","https://openalex.org/W4384561507","https://openalex.org/W4386083883","https://openalex.org/W4389543157","https://openalex.org/W6784333009","https://openalex.org/W6852924859","https://openalex.org/W6852931934","https://openalex.org/W6853023569"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2118717649","https://openalex.org/W2413243053","https://openalex.org/W410723623","https://openalex.org/W2015341305","https://openalex.org/W2035068594","https://openalex.org/W4225593417","https://openalex.org/W2573498121","https://openalex.org/W3204019825"],"abstract_inverted_index":{"Segmentation":[0],"of":[1,47,112,124,134],"brain":[2,34],"tumors":[3],"in":[4,39,54,120],"multi-parametric":[5],"magnetic":[6],"resonance":[7],"imaging":[8],"facilitates":[9],"quantitative":[10],"analysis":[11],"crucial":[12],"for":[13,138],"clinical":[14,23],"trials":[15],"and":[16,27,29,128,144],"personalized":[17],"patient":[18,31],"care.":[19],"This":[20],"significantly":[21],"influences":[22],"decision-making,":[24],"encompassing":[25],"diagnosis":[26],"prognosis":[28],"enhancing":[30,140],"outcomes.":[32],"The":[33,110],"tumor":[35,51,108,142],"segmentation":[36,80],"(BraTS)":[37],"challenge,":[38],"its":[40,62],"2023":[41],"edition,":[42],"extended":[43],"to":[44,99],"a":[45,73,86,93],"cluster":[46],"competitions":[48],"incorporating":[49],"multiple":[50],"types.":[52,109],"Now,":[53],"conjunction":[55],"with":[56],"IEEE":[57],"ISBI":[58],"2024,":[59],"BraTS":[60],"organizes":[61],"Generalizability":[63],"Across":[64],"Tumors":[65],"(BraTS-GoAT)":[66],"challenge.":[67],"In":[68],"this":[69],"paper,":[70],"we":[71,83],"introduce":[72,85],"deep-learning-based":[74],"ensemble":[75],"strategy":[76],"involving":[77],"three":[78],"state-of-the-art":[79],"models.":[81],"Furthermore,":[82],"also":[84],"novel":[87],"adaptive":[88],"post-processing":[89],"method,":[90],"based":[91],"on":[92,116],"cross-validated":[94],"tumor-specific":[95],"threshold":[96],"search,":[97],"designed":[98],"output":[100],"enhanced":[101],"accurate":[102],"segmentations,":[103],"ensuring":[104],"generalizability":[105],"across":[106],"various":[107],"evaluation":[111],"our":[113],"proposed":[114],"method":[115],"validation":[117],"cases":[118],"resulted":[119],"lesion-wise":[121,129],"Dice":[122],"scores":[123,133],"0.842,":[125],"0.854,":[126],"0.872":[127],"95th-percentile":[130],"Hausdorff":[131],"Distance":[132],"29.46,":[135],"24.67,":[136],"25.22":[137],"the":[139],"tumor,":[141,146],"core,":[143],"whole":[145],"respectively.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}