{"id":"https://openalex.org/W4386350460","doi":"https://doi.org/10.1109/isbi53787.2023.10230782","title":"Multitask Learning for Improved Late Mechanical Activation Detection of Heart from Cine Dense MRI","display_name":"Multitask Learning for Improved Late Mechanical Activation Detection of Heart from Cine Dense MRI","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4386350460","doi":"https://doi.org/10.1109/isbi53787.2023.10230782","pmid":"https://pubmed.ncbi.nlm.nih.gov/40124116"},"language":"en","primary_location":{"id":"doi:10.1109/isbi53787.2023.10230782","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi53787.2023.10230782","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11929564/pdf/nihms-2065981.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053371530","display_name":"Jiarui Xing","orcid":null},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiarui Xing","raw_affiliation_strings":["University of Virginia,Department of Electrical and Computer Engineering,USA","Department of Electrical and Computer Engineering, University of Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia,Department of Electrical and Computer Engineering,USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Virginia, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100400118","display_name":"Shuo Wang","orcid":"https://orcid.org/0000-0001-5095-1435"},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuo Wang","raw_affiliation_strings":["University of Virginia Health System,School of Medicine,USA","School of Medicine, University of Virginia Health System, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia Health System,School of Medicine,USA","institution_ids":["https://openalex.org/I2799765794"]},{"raw_affiliation_string":"School of Medicine, University of Virginia Health System, USA","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063695524","display_name":"Kenneth C. Bilchick","orcid":"https://orcid.org/0000-0002-5188-3603"},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth C. Bilchick","raw_affiliation_strings":["University of Virginia Health System,School of Medicine,USA","School of Medicine, University of Virginia Health System, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia Health System,School of Medicine,USA","institution_ids":["https://openalex.org/I2799765794"]},{"raw_affiliation_string":"School of Medicine, University of Virginia Health System, USA","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065140237","display_name":"Frederick H. Epstein","orcid":"https://orcid.org/0000-0002-1954-1988"},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frederick H. Epstein","raw_affiliation_strings":["University of Virginia Health System,Department of Biomedical Engineering,USA","Department of Biomedical Engineering, University of Virginia Health System, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia Health System,Department of Biomedical Engineering,USA","institution_ids":["https://openalex.org/I2799765794"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Virginia Health System, USA","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039107780","display_name":"Amit R. Patel","orcid":"https://orcid.org/0000-0001-7621-6463"},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit R. Patel","raw_affiliation_strings":["University of Virginia Health System,School of Medicine,USA","School of Medicine, University of Virginia Health System, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia Health System,School of Medicine,USA","institution_ids":["https://openalex.org/I2799765794"]},{"raw_affiliation_string":"School of Medicine, University of Virginia Health System, USA","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100357912","display_name":"Miaomiao Zhang","orcid":"https://orcid.org/0000-0003-0457-3335"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miaomiao Zhang","raw_affiliation_strings":["University of Virginia,Department of Electrical and Computer Engineering,USA","Department of Computer Science, University of Virginia, USA","Department of Electrical and Computer Engineering, University of Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia,Department of Electrical and Computer Engineering,USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Computer Science, University of Virginia, USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Virginia, USA","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8245,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.76272196,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"2023","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.7531396150588989},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6380090713500977},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6035088300704956},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.561824381351471},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5031341910362244},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.48325592279434204},{"id":"https://openalex.org/keywords/cardiac-resynchronization-therapy","display_name":"Cardiac resynchronization therapy","score":0.4129182696342468},{"id":"https://openalex.org/keywords/heart-failure","display_name":"Heart failure","score":0.18903490900993347},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.17959389090538025},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.16454961895942688},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1351337432861328}],"concepts":[{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.7531396150588989},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6380090713500977},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6035088300704956},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.561824381351471},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5031341910362244},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.48325592279434204},{"id":"https://openalex.org/C2776034619","wikidata":"https://www.wikidata.org/wiki/Q3428020","display_name":"Cardiac resynchronization therapy","level":4,"score":0.4129182696342468},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.18903490900993347},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17959389090538025},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.16454961895942688},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1351337432861328},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi53787.2023.10230782","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi53787.2023.10230782","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:40124116","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40124116","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11929564","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11929564","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11929564/pdf/nihms-2065981.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11929564","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11929564","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11929564/pdf/nihms-2065981.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3429725638","display_name":null,"funder_award_id":"R21 EB032597","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4386350460.pdf"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W203530735","https://openalex.org/W1522301498","https://openalex.org/W1818584899","https://openalex.org/W1998999499","https://openalex.org/W2047198412","https://openalex.org/W2063467501","https://openalex.org/W2100056258","https://openalex.org/W2104095591","https://openalex.org/W2131241448","https://openalex.org/W2143419558","https://openalex.org/W2145240384","https://openalex.org/W2146521529","https://openalex.org/W2567973848","https://openalex.org/W2913340405","https://openalex.org/W2962858109","https://openalex.org/W3164435966","https://openalex.org/W4307823382","https://openalex.org/W6631190155","https://openalex.org/W6678911119"],"related_works":["https://openalex.org/W2111887156","https://openalex.org/W2051061635","https://openalex.org/W2594890226","https://openalex.org/W4220884743","https://openalex.org/W2013162077","https://openalex.org/W2592912933","https://openalex.org/W2740060271","https://openalex.org/W2141214479","https://openalex.org/W2966415242","https://openalex.org/W2371084835"],"abstract_inverted_index":{"The":[0],"selection":[1],"of":[2,19,27,33,43,131,138],"an":[3],"optimal":[4],"pacing":[5],"site,":[6],"which":[7],"is":[8,14],"ideally":[9],"scar-free":[10,78],"and":[11,75,125,150],"late":[12,35],"activated,":[13],"critical":[15],"to":[16,109,178],"the":[17,25,31,77,110,129,136,152,156,172,180,196],"response":[18],"cardiac":[20,147],"resynchronization":[21],"therapy":[22],"(CRT).":[23],"Despite":[24],"success":[26],"current":[28],"approaches":[29],"formulating":[30],"detection":[32],"such":[34],"mechanical":[36],"activation":[37,44,175],"(LMA)":[38],"regions":[39,80],"as":[40],"a":[41,65,95],"problem":[42],"time":[45],"regression,":[46],"their":[47,119],"accuracy":[48],"remains":[49],"unsatisfactory,":[50],"particularly":[51],"in":[52,122,126],"cases":[53],"where":[54],"myocardial":[55,115],"scar":[56,132],"exists.":[57],"To":[58,134],"address":[59],"this":[60,62],"issue,":[61],"paper":[63],"introduces":[64],"multi-task":[66],"deep":[67],"learning":[68],"framework":[69],"that":[70,161,190],"simultaneously":[71],"estimates":[72],"LMA":[73,79,99,123,154,197],"amount":[74],"classify":[76],"based":[81],"on":[82,145],"cine":[83],"displacement":[84],"encoding":[85],"with":[86,155],"stimulated":[87],"echoes":[88],"(DENSE)":[89],"magnetic":[90],"resonance":[91],"imaging":[92],"(MRI).":[93],"With":[94],"newly":[96],"introduced":[97],"auxiliary":[98],"region":[100,198],"classification":[101],"sub-network,":[102],"our":[103,139,143,162,191],"proposed":[104,192],"model":[105,144,193],"shows":[106,160],"more":[107],"robustness":[108],"complex":[111],"pattern":[112],"cause":[113],"by":[114,184],"scar,":[116],"significantly":[117],"eliminates":[118],"negative":[120],"effects":[121],"detection,":[124],"turn":[127],"improves":[128],"performance":[130],"classification.":[133],"evaluate":[135],"effectiveness":[137],"method,":[140],"we":[141,170],"tests":[142],"real":[146],"MR":[148],"images":[149],"compare":[151],"predicted":[153],"state-of-the-art":[157],"approaches.":[158],"It":[159],"approach":[163],"achieves":[164],"substantially":[165],"increased":[166],"accuracy.":[167],"In":[168],"addition,":[169],"employ":[171],"gradient-weighted":[173],"class":[174],"mapping":[176],"(Grad-CAM)":[177],"visualize":[179],"feature":[181],"maps":[182],"learned":[183],"all":[185],"methods.":[186],"Experimental":[187],"results":[188],"suggest":[189],"better":[194],"recognizes":[195],"pattern.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2}],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2025-10-10T00:00:00"}