{"id":"https://openalex.org/W4386362858","doi":"https://doi.org/10.1109/isbi53787.2023.10230742","title":"Supervised Deep Tree in Alzheimer\u2019s Disease","display_name":"Supervised Deep Tree in Alzheimer\u2019s Disease","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4386362858","doi":"https://doi.org/10.1109/isbi53787.2023.10230742","pmid":"https://pubmed.ncbi.nlm.nih.gov/38362508"},"language":"en","primary_location":{"id":"doi:10.1109/isbi53787.2023.10230742","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi53787.2023.10230742","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10869122/pdf/nihms-1923567.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062577958","display_name":"Xiaowei Yu","orcid":"https://orcid.org/0000-0002-5599-8424"},"institutions":[{"id":"https://openalex.org/I189196454","display_name":"The University of Texas at Arlington","ror":"https://ror.org/019kgqr73","country_code":"US","type":"education","lineage":["https://openalex.org/I189196454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xiaowei Yu","raw_affiliation_strings":["University of Texas at Arlington,Computer Science and Engineering,TX,USA","Computer Science and Engineering, University of Texas at Arlington, TX, USA"],"affiliations":[{"raw_affiliation_string":"University of Texas at Arlington,Computer Science and Engineering,TX,USA","institution_ids":["https://openalex.org/I189196454"]},{"raw_affiliation_string":"Computer Science and Engineering, University of Texas at Arlington, TX, USA","institution_ids":["https://openalex.org/I189196454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100388585","display_name":"Lu Zhang","orcid":"https://orcid.org/0000-0001-9072-5854"},"institutions":[{"id":"https://openalex.org/I189196454","display_name":"The University of Texas at Arlington","ror":"https://ror.org/019kgqr73","country_code":"US","type":"education","lineage":["https://openalex.org/I189196454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lu Zhang","raw_affiliation_strings":["University of Texas at Arlington,Computer Science and Engineering,TX,USA","Computer Science and Engineering, University of Texas at Arlington, TX, USA"],"affiliations":[{"raw_affiliation_string":"University of Texas at Arlington,Computer Science and Engineering,TX,USA","institution_ids":["https://openalex.org/I189196454"]},{"raw_affiliation_string":"Computer Science and Engineering, University of Texas at Arlington, TX, USA","institution_ids":["https://openalex.org/I189196454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053007087","display_name":"Yanjun Lyu","orcid":"https://orcid.org/0000-0003-1243-233X"},"institutions":[{"id":"https://openalex.org/I189196454","display_name":"The University of Texas at Arlington","ror":"https://ror.org/019kgqr73","country_code":"US","type":"education","lineage":["https://openalex.org/I189196454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanjun Lyu","raw_affiliation_strings":["University of Texas at Arlington,Computer Science and Engineering,TX,USA","Computer Science and Engineering, University of Texas at Arlington, TX, USA"],"affiliations":[{"raw_affiliation_string":"University of Texas at Arlington,Computer Science and Engineering,TX,USA","institution_ids":["https://openalex.org/I189196454"]},{"raw_affiliation_string":"Computer Science and Engineering, University of Texas at Arlington, TX, USA","institution_ids":["https://openalex.org/I189196454"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100647156","display_name":"Tianming Liu","orcid":"https://orcid.org/0000-0002-8132-9048"},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tianming Liu","raw_affiliation_strings":["The University of Georgia,Computer Science,Athens,USA","Computer Science, The University of Georgia, Athens, USA"],"affiliations":[{"raw_affiliation_string":"The University of Georgia,Computer Science,Athens,USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"Computer Science, The University of Georgia, Athens, USA","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038582366","display_name":"Dajiang Zhu","orcid":"https://orcid.org/0000-0002-6940-3911"},"institutions":[{"id":"https://openalex.org/I189196454","display_name":"The University of Texas at Arlington","ror":"https://ror.org/019kgqr73","country_code":"US","type":"education","lineage":["https://openalex.org/I189196454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dajiang Zhu","raw_affiliation_strings":["University of Texas at Arlington,Computer Science and Engineering,TX,USA","Computer Science and Engineering, University of Texas at Arlington, TX, USA"],"affiliations":[{"raw_affiliation_string":"University of Texas at Arlington,Computer Science and Engineering,TX,USA","institution_ids":["https://openalex.org/I189196454"]},{"raw_affiliation_string":"Computer Science and Engineering, University of Texas at Arlington, TX, USA","institution_ids":["https://openalex.org/I189196454"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5062577958"],"corresponding_institution_ids":["https://openalex.org/I189196454"],"apc_list":null,"apc_paid":null,"fwci":2.104,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.87422017,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"2023","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9659000039100647,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9659000039100647,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.948199987411499,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9383999705314636,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5742436647415161},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5273260474205017},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5062974691390991},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.5007636547088623},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20063626766204834},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15325874090194702},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.06634590029716492},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.06559678912162781}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5742436647415161},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5273260474205017},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5062974691390991},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5007636547088623},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20063626766204834},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15325874090194702},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06634590029716492},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.06559678912162781}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi53787.2023.10230742","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi53787.2023.10230742","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:38362508","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38362508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10869122","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10869122","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10869122/pdf/nihms-1923567.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10869122","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10869122","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10869122/pdf/nihms-1923567.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386362858.pdf"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1981115828","https://openalex.org/W1997417397","https://openalex.org/W2008301592","https://openalex.org/W2038003677","https://openalex.org/W2040434160","https://openalex.org/W2049943618","https://openalex.org/W2072361983","https://openalex.org/W2119848633","https://openalex.org/W2144631174","https://openalex.org/W2145450560","https://openalex.org/W2150667092","https://openalex.org/W2167720733","https://openalex.org/W2167840686","https://openalex.org/W2527896982","https://openalex.org/W2533064745","https://openalex.org/W2791743234","https://openalex.org/W3026450975","https://openalex.org/W3028024203","https://openalex.org/W3157129463","https://openalex.org/W4206046172","https://openalex.org/W4206774749","https://openalex.org/W4210354859","https://openalex.org/W4224285717","https://openalex.org/W4296120751","https://openalex.org/W6810624682"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"As":[0],"a":[1,37,97,120,124],"progressive":[2],"neurodegenerative":[3],"disorder,":[4],"the":[5,20,26,29,65,72,86,115,135,143,146,157,172],"pathological":[6],"changes":[7],"of":[8,22,28,32,64,74,90,117,137,159],"Alzheimer's":[9,180],"disease":[10,42],"(AD)":[11],"might":[12],"begin":[13],"as":[14,16,119],"much":[15],"two":[17],"decades":[18],"before":[19],"manifestation":[21],"clinical":[23],"symptoms.":[24],"Since":[25],"nature":[27],"irreversible":[30],"pathology":[31],"AD,":[33],"early":[34,53],"diagnosis":[35],"provides":[36],"more":[38],"tractable":[39],"way":[40],"for":[41,52,164],"intervention":[43],"and":[44,107,175],"treatment.":[45],"Therefore,":[46],"numerous":[47],"approaches":[48],"have":[49,60],"been":[50,61],"developed":[51],"diagnostic":[54],"purposes.":[55],"Although":[56],"several":[57],"important":[58],"biomarkers":[59],"established,":[62],"most":[63],"existing":[66],"methods":[67],"show":[68],"limitations":[69],"in":[70,123],"describing":[71],"continuum":[73,136,158],"AD":[75,105,118,138,160],"progression.":[76],"However,":[77],"understanding":[78],"this":[79,93,133],"continuous":[80],"development":[81],"is":[82,140],"essential":[83],"to":[84,103],"understand":[85],"intrinsic":[87],"progression":[88,106,116,139],"mechanism":[89],"AD.":[91],"In":[92,132],"work,":[94],"we":[95],"proposed":[96,111],"supervised":[98],"deep":[99],"tree":[100,121,147,151],"model":[101],"(SDTree)":[102],"integrate":[104],"individual":[108],"prediction.":[109],"The":[110,149],"SDTree":[112],"method":[113,170],"models":[114],"embedded":[122],"latent":[125],"space":[126],"using":[127],"nonlinear":[128],"reversed":[129],"graph":[130],"embedding.":[131],"way,":[134],"encoded":[141],"into":[142],"locations":[144],"on":[145,171,179],"structure.":[148],"learned":[150],"structure":[152],"can":[153],"not":[154],"only":[155],"represent":[156],"but":[161],"make":[162],"predictions":[163],"new":[165],"subjects.":[166],"We":[167],"evaluated":[168],"our":[169],"classification":[173],"task":[174],"achieved":[176],"promising":[177],"results":[178],"Disease":[181],"Neuroimaging":[182],"Initiative":[183],"dataset.":[184]},"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2}],"updated_date":"2026-03-13T16:22:10.518609","created_date":"2025-10-10T00:00:00"}