{"id":"https://openalex.org/W4386362536","doi":"https://doi.org/10.1109/isbi53787.2023.10230526","title":"A Spatiotemporal Illumination Model for 3d Image Fusion in Optical Coherence Tomography","display_name":"A Spatiotemporal Illumination Model for 3d Image Fusion in Optical Coherence Tomography","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4386362536","doi":"https://doi.org/10.1109/isbi53787.2023.10230526"},"language":"en","primary_location":{"id":"doi:10.1109/isbi53787.2023.10230526","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi53787.2023.10230526","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["arxiv","crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2402.12114","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076283550","display_name":"Stefan B. Ploner","orcid":"https://orcid.org/0000-0003-4286-8687"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stefan Ploner","raw_affiliation_strings":["Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany","Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany","institution_ids":[]},{"raw_affiliation_string":"Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079735026","display_name":"Jungeun Won","orcid":"https://orcid.org/0000-0003-1007-4049"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jungeun Won","raw_affiliation_strings":["Massachusetts Institute of Technology,Research Laboratory of Electronics,Cambridge,MA,USA","Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,Research Laboratory of Electronics,Cambridge,MA,USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037206757","display_name":"Julia Schottenhamml","orcid":"https://orcid.org/0000-0002-9145-9102"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia Schottenhamml","raw_affiliation_strings":["Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany"],"affiliations":[{"raw_affiliation_string":"Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104123530","display_name":"Jessica M. Girgis","orcid":null},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I4210120726","display_name":"Eye Center","ror":"https://ror.org/02jecxg34","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210120726"]}],"countries":["SA","US"],"is_corresponding":false,"raw_author_name":"Jessica Girgis","raw_affiliation_strings":["New England Eye Center,Department of Ophthalmology,Boston,MA,USA","Department of Ophthalmology, New England Eye Center, Boston, MA, USA"],"affiliations":[{"raw_affiliation_string":"New England Eye Center,Department of Ophthalmology,Boston,MA,USA","institution_ids":["https://openalex.org/I4210120726","https://openalex.org/I1287163989"]},{"raw_affiliation_string":"Department of Ophthalmology, New England Eye Center, Boston, MA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012142510","display_name":"Kenneth C. Lam","orcid":"https://orcid.org/0000-0002-2185-0990"},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I4210120726","display_name":"Eye Center","ror":"https://ror.org/02jecxg34","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210120726"]}],"countries":["SA","US"],"is_corresponding":false,"raw_author_name":"Kenneth Lam","raw_affiliation_strings":["New England Eye Center,Department of Ophthalmology,Boston,MA,USA","Department of Ophthalmology, New England Eye Center, Boston, MA, USA"],"affiliations":[{"raw_affiliation_string":"New England Eye Center,Department of Ophthalmology,Boston,MA,USA","institution_ids":["https://openalex.org/I4210120726","https://openalex.org/I1287163989"]},{"raw_affiliation_string":"Department of Ophthalmology, New England Eye Center, Boston, MA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030633237","display_name":"Nadia K. Waheed","orcid":"https://orcid.org/0000-0002-8229-7519"},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I4210120726","display_name":"Eye Center","ror":"https://ror.org/02jecxg34","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210120726"]}],"countries":["SA","US"],"is_corresponding":false,"raw_author_name":"Nadia Waheed","raw_affiliation_strings":["New England Eye Center,Department of Ophthalmology,Boston,MA,USA","Department of Ophthalmology, New England Eye Center, Boston, MA, USA"],"affiliations":[{"raw_affiliation_string":"New England Eye Center,Department of Ophthalmology,Boston,MA,USA","institution_ids":["https://openalex.org/I4210120726","https://openalex.org/I1287163989"]},{"raw_affiliation_string":"Department of Ophthalmology, New England Eye Center, Boston, MA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019768182","display_name":"James G. Fujimoto","orcid":"https://orcid.org/0000-0002-0828-4357"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Fujimoto","raw_affiliation_strings":["Massachusetts Institute of Technology,Research Laboratory of Electronics,Cambridge,MA,USA","Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,Research Laboratory of Electronics,Cambridge,MA,USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101619735","display_name":"Andreas Maier","orcid":"https://orcid.org/0000-0002-9550-5284"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andreas Maier","raw_affiliation_strings":["Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany"],"affiliations":[{"raw_affiliation_string":"Friedrich-Alexander-Universität Erlangen-Nürnberg,Pattern Recognition Lab,Erlangen,Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5076283550"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":0.544,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.61505347,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11377","display_name":"Retinal and Macular Surgery","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.7812380790710449},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.6831102967262268},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6448547840118408},{"id":"https://openalex.org/keywords/raster-scan","display_name":"Raster scan","score":0.6344654560089111},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6172024011611938},{"id":"https://openalex.org/keywords/raster-graphics","display_name":"Raster graphics","score":0.5788632035255432},{"id":"https://openalex.org/keywords/classification-of-discontinuities","display_name":"Classification of discontinuities","score":0.5169307589530945},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.45429813861846924},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.4532044231891632},{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.42353278398513794},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3592449426651001},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.2181609570980072},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18589594960212708},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.18438470363616943}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.7812380790710449},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.6831102967262268},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6448547840118408},{"id":"https://openalex.org/C145406643","wikidata":"https://www.wikidata.org/wiki/Q2641959","display_name":"Raster scan","level":2,"score":0.6344654560089111},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6172024011611938},{"id":"https://openalex.org/C181844469","wikidata":"https://www.wikidata.org/wiki/Q182270","display_name":"Raster graphics","level":2,"score":0.5788632035255432},{"id":"https://openalex.org/C15627037","wikidata":"https://www.wikidata.org/wiki/Q541961","display_name":"Classification of discontinuities","level":2,"score":0.5169307589530945},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.45429813861846924},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4532044231891632},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.42353278398513794},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3592449426651001},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.2181609570980072},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18589594960212708},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18438470363616943},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi53787.2023.10230526","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi53787.2023.10230526","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:arXiv.org:2402.12114","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2402.12114","pdf_url":"https://arxiv.org/pdf/2402.12114","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2402.12114","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2402.12114","pdf_url":"https://arxiv.org/pdf/2402.12114","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3789688987","display_name":null,"funder_award_id":"508075009","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4951618211","display_name":null,"funder_award_id":"5-R01-","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5106512922","display_name":null,"funder_award_id":"Deutsche Forschungsgemeinschaft (DFG","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7560515207","display_name":null,"funder_award_id":"R01-EY011289","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4386362536.pdf"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W2014210274","https://openalex.org/W2418802570","https://openalex.org/W2418833711","https://openalex.org/W2474279305","https://openalex.org/W2519115761","https://openalex.org/W2775636951","https://openalex.org/W2905349048","https://openalex.org/W2955200554","https://openalex.org/W2992783718","https://openalex.org/W3034580843","https://openalex.org/W3093201159","https://openalex.org/W3158049181","https://openalex.org/W4295939676","https://openalex.org/W6765152186"],"related_works":["https://openalex.org/W1984055937","https://openalex.org/W4385770201","https://openalex.org/W1974004953","https://openalex.org/W2072796508","https://openalex.org/W204409194","https://openalex.org/W2093392189","https://openalex.org/W2377833861","https://openalex.org/W2028294394","https://openalex.org/W2027078417","https://openalex.org/W1983764641"],"abstract_inverted_index":{"Optical":[0],"coherence":[1],"tomography":[2],"(OCT)":[3],"is":[4,96,149],"a":[5,13,49,101],"non-invasive,":[6],"micrometer-scale":[7],"imaging":[8,33],"modality":[9],"that":[10,39,53],"has":[11],"become":[12],"clinical":[14],"standard":[15],"in":[16,56,79,105,110,113,125,160],"ophthalmology.":[17],"By":[18],"raster-scanning":[19],"the":[20,72,80,97,128,141],"retina,":[21],"sequential":[22],"cross-sectional":[23],"image":[24,107,158],"slices":[25,38],"are":[26],"acquired":[27],"to":[28,66],"generate":[29],"volumetric":[30],"data.":[31,60],"In-vivo":[32],"suffers":[34],"from":[35,116],"discontinuities":[36],"between":[37],"show":[40],"up":[41],"as":[42,75,77],"motion":[43,145],"and":[44,130,152,155],"illumination":[45,51,67,123,136],"artifacts.":[46,137],"We":[47],"present":[48],"new":[50],"model":[52,104],"exploits":[54],"continuity":[55,68],"orthogonally":[57],"raster-scanned":[58],"volume":[59],"Our":[61],"novel":[62],"spatiotemporal":[63],"parametrization":[64],"adheres":[65],"both":[69],"temporally,":[70],"along":[71],"imaged":[73],"slices,":[74],"well":[76],"spatially,":[78],"transverse":[81],"directions.":[82],"Yet,":[83],"our":[84],"formulation":[85],"does":[86],"not":[87],"make":[88],"inter-slice":[89],"assumptions,":[90],"which":[91,148],"could":[92],"have":[93],"discontinuities.":[94],"This":[95],"first":[98],"optimization":[99],"of":[100,122,127,143],"3D":[102,157],"inverse":[103],"an":[106],"reconstruction":[108,159],"context":[109],"OCT.":[111,161],"Evaluation":[112],"68":[114],"volumes":[115],"eyes":[117],"with":[118],"pathology":[119],"showed":[120,133],"reduction":[121],"artifacts":[124],"88%":[126],"data,":[129,147],"only":[131],"6%":[132],"moderate":[134],"residual":[135],"The":[138],"method":[139],"enables":[140,153],"use":[142],"forward-warped":[144],"corrected":[146],"more":[150],"accurate,":[151],"supersampling":[154],"advanced":[156]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}