{"id":"https://openalex.org/W4386352840","doi":"https://doi.org/10.1109/isbi53787.2023.10230388","title":"A Robust Framework of Chromosome Straightening With Vit-Patch Gan","display_name":"A Robust Framework of Chromosome Straightening With Vit-Patch Gan","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4386352840","doi":"https://doi.org/10.1109/isbi53787.2023.10230388"},"language":"en","primary_location":{"id":"doi:10.1109/isbi53787.2023.10230388","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi53787.2023.10230388","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004127475","display_name":"Sifan Song","orcid":"https://orcid.org/0000-0002-7940-650X"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]},{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["CN","GB"],"is_corresponding":true,"raw_author_name":"Sifan Song","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China","University of Liverpool, Liverpool, UK"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344687","display_name":"Jinfeng Wang","orcid":"https://orcid.org/0000-0002-9086-7518"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]},{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Jinfeng Wang","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China","University of Liverpool, Liverpool, UK"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035380092","display_name":"Fengrui Cheng","orcid":"https://orcid.org/0000-0002-5261-1028"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengrui Cheng","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042816775","display_name":"Qirui Cao","orcid":"https://orcid.org/0000-0002-4914-318X"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qirui Cao","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033259258","display_name":"Yi-Han Zuo","orcid":null},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yihan Zuo","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042656787","display_name":"Yongteng Lei","orcid":null},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongteng Lei","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036931546","display_name":"Ruomai Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruomai Yang","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100746496","display_name":"Chunxiao Yang","orcid":"https://orcid.org/0000-0003-2116-3354"},"institutions":[{"id":"https://openalex.org/I4210125878","display_name":"Suzhou Research Institute","ror":"https://ror.org/03ebk0c60","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210125878"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxiao Yang","raw_affiliation_strings":["Suzhou Sano Precision Medicine Ltd.,Suzhou,China","Suzhou Sano Precision Medicine Ltd., Suzhou, China"],"affiliations":[{"raw_affiliation_string":"Suzhou Sano Precision Medicine Ltd.,Suzhou,China","institution_ids":["https://openalex.org/I4210125878"]},{"raw_affiliation_string":"Suzhou Sano Precision Medicine Ltd., Suzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073606016","display_name":"Frans Coenen","orcid":"https://orcid.org/0000-0003-1026-6649"},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Frans Coenen","raw_affiliation_strings":["University of Liverpool,Liverpool,UK","University of Liverpool, Liverpool, UK"],"affiliations":[{"raw_affiliation_string":"University of Liverpool,Liverpool,UK","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062986831","display_name":"Jia Meng","orcid":"https://orcid.org/0000-0003-3455-205X"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Meng","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101105741","display_name":"Kang Dang","orcid":"https://orcid.org/0000-0003-0613-2787"},"institutions":[{"id":"https://openalex.org/I4210107590","display_name":"Voxtel (United States)","ror":"https://ror.org/01wywrx16","country_code":"US","type":"company","lineage":["https://openalex.org/I4210107590"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kang Dang","raw_affiliation_strings":["VoxelCloud, Inc.,Los Angeles,USA","VoxelCloud, Inc., Los Angeles, USA"],"affiliations":[{"raw_affiliation_string":"VoxelCloud, Inc.,Los Angeles,USA","institution_ids":["https://openalex.org/I4210107590"]},{"raw_affiliation_string":"VoxelCloud, Inc., Los Angeles, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085156744","display_name":"Jionglong Su","orcid":"https://orcid.org/0000-0001-5360-6493"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jionglong Su","raw_affiliation_strings":["Xi’an Jiaotong-Liverpool University,Suzhou,China"],"affiliations":[{"raw_affiliation_string":"Xi’an Jiaotong-Liverpool University,Suzhou,China","institution_ids":["https://openalex.org/I69356397"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5004127475"],"corresponding_institution_ids":["https://openalex.org/I146655781","https://openalex.org/I69356397"],"apc_list":null,"apc_paid":null,"fwci":0.9633,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.80481213,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"32","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6245668530464172},{"id":"https://openalex.org/keywords/discriminator","display_name":"Discriminator","score":0.5846529006958008},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5690854787826538},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.5117713809013367},{"id":"https://openalex.org/keywords/karyotype","display_name":"Karyotype","score":0.5014245510101318},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.46848973631858826},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4312973916530609},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20440346002578735},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17086845636367798},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.09589114785194397}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6245668530464172},{"id":"https://openalex.org/C2779803651","wikidata":"https://www.wikidata.org/wiki/Q5282088","display_name":"Discriminator","level":3,"score":0.5846529006958008},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5690854787826538},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5117713809013367},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.5014245510101318},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.46848973631858826},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4312973916530609},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20440346002578735},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17086845636367798},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.09589114785194397},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi53787.2023.10230388","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/isbi53787.2023.10230388","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6200000047683716,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1964569440","https://openalex.org/W2012031796","https://openalex.org/W2060084956","https://openalex.org/W2071370054","https://openalex.org/W2134871593","https://openalex.org/W2194775991","https://openalex.org/W2736536606","https://openalex.org/W2794198923","https://openalex.org/W2885847278","https://openalex.org/W2890193969","https://openalex.org/W2891173463","https://openalex.org/W2912101381","https://openalex.org/W2962785568","https://openalex.org/W2963073614","https://openalex.org/W2963446712","https://openalex.org/W2988066048","https://openalex.org/W3008823916","https://openalex.org/W3094502228","https://openalex.org/W3131457306","https://openalex.org/W3135174958","https://openalex.org/W3178284600","https://openalex.org/W4283820236","https://openalex.org/W4301206121","https://openalex.org/W6729966448","https://openalex.org/W6765779288","https://openalex.org/W6767264202"],"related_works":["https://openalex.org/W2108498225","https://openalex.org/W2390806584","https://openalex.org/W2357064814","https://openalex.org/W4312270766","https://openalex.org/W2060929468","https://openalex.org/W2586947668","https://openalex.org/W2022999990","https://openalex.org/W2390766987","https://openalex.org/W2353740429","https://openalex.org/W2015266748"],"abstract_inverted_index":{"Chromosomes":[0],"carry":[1],"the":[2,42,87,95,98,101,116],"genetic":[3],"information":[4],"of":[5,16,44,71,90,97],"humans.":[6],"They":[7],"exhibit":[8],"non-rigid":[9],"and":[10,30,50,77,107,133,138],"non-articulated":[11],"nature":[12],"with":[13],"varying":[14],"degrees":[15],"curvature.":[17],"Chromosome":[18],"straightening":[19,37],"is":[20],"an":[21],"important":[22],"step":[23],"for":[24,92],"subsequent":[25],"karyotype":[26],"construction,":[27],"pathological":[28],"diagnosis":[29],"cytogenetic":[31],"map":[32],"development.":[33],"However,":[34],"robust":[35],"chromosome":[36,48,135],"remains":[38],"challenging,":[39],"due":[40],"to":[41],"unavailability":[43],"training":[45],"images,":[46],"distorted":[47],"details":[49],"shapes":[51],"after":[52],"straightening,":[53],"as":[54,56],"well":[55],"poor":[57],"generalization":[58,141],"capability.":[59],"In":[60],"this":[61],"paper,":[62],"we":[63],"propose":[64],"a":[65,72,78,144],"novel":[66],"architecture,":[67],"ViT-Patch":[68,99],"GAN,":[69],"consisting":[70],"self-learned":[73],"motion":[74,88],"transformation":[75],"generator":[76,85],"Vision":[79],"Transformer-based":[80],"patch":[81],"(ViT-Patch)":[82],"discriminator.":[83],"The":[84,111],"learns":[86],"representation":[89],"chromosomes":[91,103],"straightening.":[93],"With":[94],"help":[96],"discriminator,":[100],"straightened":[102],"retain":[104],"more":[105],"shape":[106],"banding":[108],"pattern":[109],"details.":[110],"experimental":[112],"results":[113],"show":[114],"that":[115],"proposed":[117],"method":[118],"achieves":[119],"better":[120],"performance":[121],"on":[122,143],"Fr\u00e9chet":[123],"Inception":[124],"Distance":[125],"(FID),":[126],"Learned":[127],"Perceptual":[128],"Image":[129],"Patch":[130],"Similarity":[131],"(LPIPS)":[132],"downstream":[134],"classification":[136],"accuracy,":[137],"shows":[139],"excellent":[140],"capability":[142],"large":[145],"dataset.":[146]},"counts_by_year":[{"year":2023,"cited_by_count":3}],"updated_date":"2025-12-22T23:10:17.713674","created_date":"2025-10-10T00:00:00"}