{"id":"https://openalex.org/W3165525854","doi":"https://doi.org/10.1109/isbi48211.2021.9434172","title":"Unsupervised Clustering Of Airway Tree Structures On High-Resolution CT: The Mesa Lung Study","display_name":"Unsupervised Clustering Of Airway Tree Structures On High-Resolution CT: The Mesa Lung Study","publication_year":2021,"publication_date":"2021-04-13","ids":{"openalex":"https://openalex.org/W3165525854","doi":"https://doi.org/10.1109/isbi48211.2021.9434172","mag":"3165525854","pmid":"https://pubmed.ncbi.nlm.nih.gov/39399779"},"language":"en","primary_location":{"id":"doi:10.1109/isbi48211.2021.9434172","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi48211.2021.9434172","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11467910","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029274900","display_name":"Artur Wysoczanski","orcid":null},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Artur Wysoczanski","raw_affiliation_strings":["Department of Biomedical Engineering, Columbia University, New York, NY, USA","Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008972669","display_name":"Elsa D. Angelini","orcid":"https://orcid.org/0000-0002-1602-300X"},"institutions":[{"id":"https://openalex.org/I4210109636","display_name":"NIHR Imperial Biomedical Research Centre","ror":"https://ror.org/01kmhx639","country_code":"GB","type":"facility","lineage":["https://openalex.org/I34931013","https://openalex.org/I4210109636"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Elsa D. Angelini","raw_affiliation_strings":["Department of Biomedical Engineering, Columbia University, New York, NY, USA","ITMAT Data Science Group, NIHR Imperial BRC, Imperial College, London, UK","Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"ITMAT Data Science Group, NIHR Imperial BRC, Imperial College, London, UK","institution_ids":["https://openalex.org/I4210109636","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043154534","display_name":"Benjamin M. Smith","orcid":"https://orcid.org/0000-0002-0619-5799"},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Benjamin M. Smith","raw_affiliation_strings":["Department of Medicine, Columbia University Medical Center, New York, NY, USA","Department of Medicine, McGill University Health Center, Montreal, QC, Canada","McGill University Health Center, Montreal, QC, Canada","Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Department of Medicine, McGill University Health Center, Montreal, QC, Canada","institution_ids":["https://openalex.org/I2801766832"]},{"raw_affiliation_string":"McGill University Health Center, Montreal, QC, Canada","institution_ids":["https://openalex.org/I2801766832"]},{"raw_affiliation_string":"Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011527598","display_name":"Eric A. Hoffman","orcid":"https://orcid.org/0000-0001-8456-9437"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric A. Hoffman","raw_affiliation_strings":["Department of Biomedical Engineering, University of Iowa, Iowa City, IA, USA","Department of Radiology, University of Iowa, Iowa City, IA, USA","University of Iowa, Iowa City, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Iowa, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Radiology, University of Iowa, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"University of Iowa, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042235995","display_name":"Grant Hiura","orcid":"https://orcid.org/0000-0001-5135-4309"},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grant T. Hiura","raw_affiliation_strings":["Department of Medicine, Columbia University Medical Center, New York, NY, USA","Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078704429","display_name":"Yifei Sun","orcid":"https://orcid.org/0000-0002-6961-5500"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yifei Sun","raw_affiliation_strings":["Department of Biostatistics, Columbia University, New York, NY, USA","Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070233463","display_name":"R. Graham Barr","orcid":"https://orcid.org/0000-0001-8021-0072"},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Graham Barr","raw_affiliation_strings":["Department of Epidemiology, Columbia University Medical Center, New York, NY, USA","Department of Medicine, Columbia University Medical Center, New York, NY, USA","Columbia University Medical Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Department of Medicine, Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Columbia University Medical Center, New York, NY, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090489079","display_name":"Andrew F. Laine","orcid":"https://orcid.org/0000-0003-3797-0628"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew F. Laine","raw_affiliation_strings":["Department of Biomedical Engineering, Columbia University, New York, NY, USA","Columbia University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1458,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49754806,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"2021","issue":null,"first_page":"1568","last_page":"1572"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/airway","display_name":"Airway","score":0.6359995007514954},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.533220648765564},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.5014266967773438},{"id":"https://openalex.org/keywords/lung","display_name":"Lung","score":0.4729951322078705},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.457328200340271},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4479793310165405},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.320473313331604},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.313349187374115},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28094878792762756},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2670470178127289},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.21429985761642456},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.16942691802978516},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.09227681159973145}],"concepts":[{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.6359995007514954},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.533220648765564},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5014266967773438},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4729951322078705},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.457328200340271},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4479793310165405},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.320473313331604},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.313349187374115},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28094878792762756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2670470178127289},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21429985761642456},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16942691802978516},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.09227681159973145},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi48211.2021.9434172","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi48211.2021.9434172","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:39399779","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39399779","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11467910","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11467910","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11467910","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11467910","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G1539384734","display_name":null,"funder_award_id":"75N92020D00001","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1803853571","display_name":null,"funder_award_id":"75N92020D00006","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2262782284","display_name":null,"funder_award_id":"N01 HC095163","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2390308769","display_name":null,"funder_award_id":"R01 HL130506","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2580996367","display_name":null,"funder_award_id":"75N92020D00007","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3467146285","display_name":null,"funder_award_id":"UL1 TR001079","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G3570589137","display_name":null,"funder_award_id":"75N92020D00002","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3687594596","display_name":null,"funder_award_id":"N01 HC095168","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4563812999","display_name":null,"funder_award_id":"75N92020D00005","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5088122703","display_name":null,"funder_award_id":"HHSN268201500003C","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G514410172","display_name":null,"funder_award_id":"75N92020D00003","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5157437253","display_name":null,"funder_award_id":"N01 HC095162","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5787256936","display_name":null,"funder_award_id":"N01 HC095167","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6359107525","display_name":null,"funder_award_id":"N01 HC095166","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6514094751","display_name":null,"funder_award_id":"N01 HC095164","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6541339090","display_name":null,"funder_award_id":"UL1 TR000040","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G6916991146","display_name":null,"funder_award_id":"R01 HL155816","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7214327690","display_name":null,"funder_award_id":"N01 HC095165","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7560043174","display_name":null,"funder_award_id":"R01 HL121270","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7611454640","display_name":null,"funder_award_id":"N01 HC095169","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7618974688","display_name":null,"funder_award_id":"R01 HL093081","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7619456116","display_name":null,"funder_award_id":"N01 HC095160","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7812722938","display_name":null,"funder_award_id":"UL1 TR001420","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G8045119095","display_name":null,"funder_award_id":"N01 HC095159","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8614520802","display_name":null,"funder_award_id":"N01 HC095161","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8714546325","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8761005068","display_name":null,"funder_award_id":"75N92020D00004","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8924857150","display_name":null,"funder_award_id":"R01 HL077612","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1597843003","https://openalex.org/W1608072211","https://openalex.org/W2110042849","https://openalex.org/W2120397327","https://openalex.org/W2124209874","https://openalex.org/W2154675536","https://openalex.org/W2156097706","https://openalex.org/W2159545748","https://openalex.org/W2195393701","https://openalex.org/W2204024259","https://openalex.org/W2753087220","https://openalex.org/W2783379777","https://openalex.org/W2975509737","https://openalex.org/W3033045524","https://openalex.org/W4210681352","https://openalex.org/W4297729182","https://openalex.org/W4301187199","https://openalex.org/W6725577755","https://openalex.org/W6753351031"],"related_works":["https://openalex.org/W4298130764","https://openalex.org/W2804364458","https://openalex.org/W2332296840","https://openalex.org/W2132641928","https://openalex.org/W4310225030","https://openalex.org/W2090259340","https://openalex.org/W1926736923","https://openalex.org/W1992973683","https://openalex.org/W2158836806","https://openalex.org/W2393816671"],"abstract_inverted_index":{"The":[0],"morphology":[1],"of":[2,27,45,70],"the":[3,12,41,46,100],"proximal":[4],"human":[5],"airway":[6,19,47,71,83,96],"tree":[7,48,72,84,97],"is":[8],"highly":[9],"variable":[10],"in":[11,18,32,36,40,74,99],"general":[13],"population,":[14],"and":[15,29,43,52,86,93],"known":[16],"variants":[17],"branching":[20],"patterns":[21],"are":[22,56],"associated":[23],"with":[24,30],"increased":[25],"risk":[26],"COPD":[28],"polymorphisms":[31],"growth":[33],"factors":[34],"involved":[35],"pulmonary":[37],"development.":[38],"Variation":[39],"geometry":[42],"topology":[44],"remains":[49],"incompletely":[50],"characterized,":[51],"their":[53],"clinical":[54],"implications":[55],"not":[57],"yet":[58],"understood.":[59],"In":[60],"this":[61],"work,":[62],"we":[63],"present":[64],"an":[65],"approach":[66],"to":[67,90],"unsupervised":[68],"clustering":[69],"structures":[73],"Billera-Holmes-Vogtmann":[75],"tree-space.":[76],"We":[77],"validate":[78],"our":[79,88],"pipeline":[80],"on":[81],"synthetic":[82],"data,":[85],"apply":[87],"algorithm":[89],"identify":[91],"reproducible":[92],"morphologically":[94],"distinct":[95],"subtypes":[98],"MESA":[101],"Lung":[102],"CT":[103],"cohort.":[104]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2025-10-10T00:00:00"}