{"id":"https://openalex.org/W3163624263","doi":"https://doi.org/10.1109/isbi48211.2021.9433998","title":"Diffraction Tomography From Single-Molecule Localization Microscopy: Numerical Feasibility","display_name":"Diffraction Tomography From Single-Molecule Localization Microscopy: Numerical Feasibility","publication_year":2021,"publication_date":"2021-04-13","ids":{"openalex":"https://openalex.org/W3163624263","doi":"https://doi.org/10.1109/isbi48211.2021.9433998","mag":"3163624263"},"language":"en","primary_location":{"id":"doi:10.1109/isbi48211.2021.9433998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi48211.2021.9433998","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://infoscience.epfl.ch/record/285133","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057509369","display_name":"Thanh-an Pham","orcid":"https://orcid.org/0000-0001-6231-2569"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Thanh-an Pham","raw_affiliation_strings":["Biomedical Imaging Group, \u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"affiliations":[{"raw_affiliation_string":"Biomedical Imaging Group, \u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082606466","display_name":"Emmanuel Soubies","orcid":"https://orcid.org/0000-0003-0571-6983"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I134560555","display_name":"Universit\u00e9 Toulouse III - Paul Sabatier","ror":"https://ror.org/02v6kpv12","country_code":"FR","type":"education","lineage":["https://openalex.org/I134560555","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I17866349","display_name":"Universit\u00e9 F\u00e9d\u00e9rale de Toulouse Midi-Pyr\u00e9n\u00e9es","ror":"https://ror.org/004raaa70","country_code":"FR","type":"education","lineage":["https://openalex.org/I17866349"]},{"id":"https://openalex.org/I3131550300","display_name":"Universit\u00e9 Toulouse-I-Capitole","ror":"https://ror.org/0443n9e75","country_code":"FR","type":"education","lineage":["https://openalex.org/I3131550300"]},{"id":"https://openalex.org/I4210119061","display_name":"Institut de Recherche en Informatique de Toulouse","ror":"https://ror.org/01rx4qw44","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I205747304","https://openalex.org/I205747304","https://openalex.org/I4210119061","https://openalex.org/I4387153255","https://openalex.org/I4405258862","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210152422","display_name":"Universit\u00e9 Toulouse - Jean Jaur\u00e8s","ror":"https://ror.org/04ezk3x31","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210152422","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210160189","display_name":"Institut Polytechnique de Bordeaux","ror":"https://ror.org/054qv7y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210160189"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel Soubies","raw_affiliation_strings":["IRIT, Universit\u00e9 de Toulouse, CNRS, Toulouse, France"],"affiliations":[{"raw_affiliation_string":"IRIT, Universit\u00e9 de Toulouse, CNRS, Toulouse, France","institution_ids":["https://openalex.org/I17866349","https://openalex.org/I134560555","https://openalex.org/I3131550300","https://openalex.org/I4210160189","https://openalex.org/I4210152422","https://openalex.org/I1294671590","https://openalex.org/I4210119061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041218961","display_name":"Ferr\u00e9ol Soulez","orcid":"https://orcid.org/0000-0001-5678-1182"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210088987","display_name":"Centre de Recherche Astrophysique de Lyon","ror":"https://ror.org/0084x3h80","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I203339264","https://openalex.org/I4210088987"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ferreol Soulez","raw_affiliation_strings":["CNRS, Centre de Recherche Astrophysique de Lyon UMR5574, Univ Lyon, Univ Lyon1, Ens de Lyon, Saint-Genis-Laval, France"],"affiliations":[{"raw_affiliation_string":"CNRS, Centre de Recherche Astrophysique de Lyon UMR5574, Univ Lyon, Univ Lyon1, Ens de Lyon, Saint-Genis-Laval, France","institution_ids":["https://openalex.org/I4210088987","https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I113428412"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027830035","display_name":"Micha\u00ebl Unser","orcid":"https://orcid.org/0000-0003-1248-2513"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Unser","raw_affiliation_strings":["Biomedical Imaging Group, \u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"affiliations":[{"raw_affiliation_string":"Biomedical Imaging Group, \u00c9cole polytechnique f\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5057509369"],"corresponding_institution_ids":["https://openalex.org/I5124864"],"apc_list":null,"apc_paid":null,"fwci":0.2408,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74622284,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"854","last_page":"857"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12466","display_name":"Near-Field Optical Microscopy","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorophore","display_name":"Fluorophore","score":0.7351080775260925},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.7259600758552551},{"id":"https://openalex.org/keywords/refractive-index","display_name":"Refractive index","score":0.619188666343689},{"id":"https://openalex.org/keywords/sample","display_name":"Sample (material)","score":0.6021744608879089},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.570258617401123},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.5463647246360779},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.47341710329055786},{"id":"https://openalex.org/keywords/tomography","display_name":"Tomography","score":0.44915902614593506},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4394306540489197},{"id":"https://openalex.org/keywords/diffraction","display_name":"Diffraction","score":0.4387267231941223},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.42643028497695923},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.4260874390602112},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.4187370836734772},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3423449993133545},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.2768048644065857},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2722773551940918},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2483130395412445}],"concepts":[{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.7351080775260925},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.7259600758552551},{"id":"https://openalex.org/C42067758","wikidata":"https://www.wikidata.org/wiki/Q174102","display_name":"Refractive index","level":2,"score":0.619188666343689},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.6021744608879089},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.570258617401123},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.5463647246360779},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.47341710329055786},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.44915902614593506},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4394306540489197},{"id":"https://openalex.org/C207114421","wikidata":"https://www.wikidata.org/wiki/Q133900","display_name":"Diffraction","level":2,"score":0.4387267231941223},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.42643028497695923},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.4260874390602112},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4187370836734772},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3423449993133545},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.2768048644065857},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2722773551940918},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2483130395412445},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi48211.2021.9433998","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi48211.2021.9433998","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:infoscience.epfl.ch:285133","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/285133","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference proceedings"}],"best_oa_location":{"id":"pmh:oai:infoscience.epfl.ch:285133","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/285133","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference proceedings"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1971144253","https://openalex.org/W1992858116","https://openalex.org/W2002832520","https://openalex.org/W2054455698","https://openalex.org/W2066521860","https://openalex.org/W2100556411","https://openalex.org/W2101336703","https://openalex.org/W2103559027","https://openalex.org/W2142224912","https://openalex.org/W2613775555","https://openalex.org/W2739527085","https://openalex.org/W2740324498","https://openalex.org/W2904170147","https://openalex.org/W2934437784","https://openalex.org/W3003820456","https://openalex.org/W3023969167","https://openalex.org/W3103758174","https://openalex.org/W3104967842","https://openalex.org/W3106431100","https://openalex.org/W3109806995","https://openalex.org/W6786440940"],"related_works":["https://openalex.org/W3044246844","https://openalex.org/W46067684","https://openalex.org/W2056518562","https://openalex.org/W2945650625","https://openalex.org/W3080939513","https://openalex.org/W1959851497","https://openalex.org/W2075666075","https://openalex.org/W3146501038","https://openalex.org/W2537408670","https://openalex.org/W2034232486"],"abstract_inverted_index":{"Single-molecule":[0],"localization":[1],"microscopy":[2,7],"(SMLM)":[3],"is":[4,96],"a":[5,37],"fluorescence":[6],"technique":[8],"that":[9,28,94,103],"achieves":[10],"super-resolution":[11],"imaging":[12],"by":[13],"sequentially":[14],"activating":[15],"and":[16],"localizing":[17],"random":[18],"sparse":[19],"subsets":[20],"of":[21,39,48,56,60,71,80],"fluorophores.":[22],"Each":[23],"activated":[24],"fluorophore":[25],"emits":[26],"light":[27],"then":[29],"scatters":[30],"through":[31],"the":[32,43,46,54,57,61,69,77,81,85,100,105],"sample,":[33,83],"thus":[34],"acting":[35],"as":[36],"source":[38],"illumination":[40],"from":[41],"inside":[42],"sample.":[44,62],"Hence,":[45],"sequence":[47],"SMLM":[49,106],"frames":[50],"carries":[51],"information":[52,74,102],"on":[53],"distribution":[55],"refractive":[58,78],"index":[59,79],"In":[63],"this":[64,73],"proof-of-concept":[65],"work,":[66],"we":[67],"explore":[68],"possibility":[70],"exploiting":[72],"to":[75,98],"recover":[76],"imaged":[82],"given":[84],"localized":[86],"molecules.":[87],"Our":[88],"results":[89],"with":[90],"simulated":[91],"data":[92],"suggest":[93],"it":[95],"possible":[97],"exploit":[99],"phase":[101],"underlies":[104],"data.":[107]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}