{"id":"https://openalex.org/W3027566228","doi":"https://doi.org/10.1109/isbi45749.2020.9098548","title":"Weakly-Supervised Prediction of Cell Migration Modes in Confocal Microscopy Images Using Bayesian Deep Learning","display_name":"Weakly-Supervised Prediction of Cell Migration Modes in Confocal Microscopy Images Using Bayesian Deep Learning","publication_year":2020,"publication_date":"2020-04-01","ids":{"openalex":"https://openalex.org/W3027566228","doi":"https://doi.org/10.1109/isbi45749.2020.9098548","mag":"3027566228"},"language":"en","primary_location":{"id":"doi:10.1109/isbi45749.2020.9098548","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098548","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042662700","display_name":"Anindya Gupta","orcid":"https://orcid.org/0000-0003-3557-4947"},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Anindya Gupta","raw_affiliation_strings":["Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden"],"affiliations":[{"raw_affiliation_string":"Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084534026","display_name":"Veronica Larsson","orcid":null},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Veronica Larsson","raw_affiliation_strings":["Karolinska Institutet, Huddinge, Sweden"],"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Huddinge, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037587888","display_name":"Damian J. Matuszewski","orcid":"https://orcid.org/0000-0002-6148-5174"},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Damian Matuszewski","raw_affiliation_strings":["Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden"],"affiliations":[{"raw_affiliation_string":"Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012387028","display_name":"Staffan Str\u00f6mblad","orcid":"https://orcid.org/0000-0002-1236-6339"},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Staffan Stromblad","raw_affiliation_strings":["Karolinska Institutet, Huddinge, Sweden"],"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Huddinge, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028372092","display_name":"Carolina W\u00e4hlby","orcid":"https://orcid.org/0000-0002-4139-7003"},"institutions":[{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]},{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carolina Wahlby","raw_affiliation_strings":["Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden"],"affiliations":[{"raw_affiliation_string":"Centre for Image Analysis, SciLifeLab, Uppsala University, Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5042662700"],"corresponding_institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.04441444,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1626","last_page":"1629"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9873999953269958,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7397512197494507},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.716134250164032},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6786774396896362},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.6354959607124329},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.6216564178466797},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5855969786643982},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.5790047645568848},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4879981577396393},{"id":"https://openalex.org/keywords/labeled-data","display_name":"Labeled data","score":0.45355042815208435},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.4386168122291565}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7397512197494507},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.716134250164032},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6786774396896362},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.6354959607124329},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.6216564178466797},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5855969786643982},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.5790047645568848},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4879981577396393},{"id":"https://openalex.org/C2776145971","wikidata":"https://www.wikidata.org/wiki/Q30673951","display_name":"Labeled data","level":2,"score":0.45355042815208435},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.4386168122291565}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi45749.2020.9098548","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098548","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","score":0.800000011920929,"display_name":"Reduced inequalities"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W149540474","https://openalex.org/W582134693","https://openalex.org/W1686810756","https://openalex.org/W1826234144","https://openalex.org/W2194775991","https://openalex.org/W2289124684","https://openalex.org/W2746791238","https://openalex.org/W2951595529","https://openalex.org/W2951965145","https://openalex.org/W2963446712","https://openalex.org/W2964059111","https://openalex.org/W2964311439","https://openalex.org/W2965563166","https://openalex.org/W2972131290","https://openalex.org/W6617145748","https://openalex.org/W6749682228"],"related_works":["https://openalex.org/W2965546495","https://openalex.org/W4389116644","https://openalex.org/W2153315159","https://openalex.org/W3103844505","https://openalex.org/W259157601","https://openalex.org/W4205463238","https://openalex.org/W2761785940","https://openalex.org/W1734881440","https://openalex.org/W1757117718","https://openalex.org/W2889166412"],"abstract_inverted_index":{"Cell":[0],"migration":[1,23,103],"is":[2,37,66],"pivotal":[3],"for":[4,33,99],"their":[5,64],"development,":[6],"physiology":[7],"and":[8,76],"disease":[9],"treatment.":[10],"A":[11],"single":[12,34],"cell":[13,28,102],"on":[14],"a":[15,128,133],"2D":[16],"surface":[17],"can":[18],"utilize":[19],"continuous":[20],"or":[21],"discontinuous":[22],"modes.":[24,104],"To":[25],"comprehend":[26],"the":[27,70,88,101,112,115,124],"migration,":[29],"an":[30],"adequate":[31],"quantification":[32],"cell-based":[35],"analysis":[36],"crucial.":[38],"An":[39],"automatized":[40],"approach":[41],"could":[42],"alleviate":[43],"tedious":[44],"manual":[45],"analysis,":[46],"facilitating":[47],"large-scale":[48],"drug":[49],"screening.":[50],"Supervised":[51],"deep":[52,83],"learning":[53,84,91],"has":[54],"shown":[55],"promising":[56],"outcomes":[57],"in":[58],"computerized":[59],"microscopy":[60],"image":[61],"analysis.":[62],"However,":[63],"implication":[65],"limited":[67],"due":[68],"to":[69,86,110],"scarcity":[71],"of":[72,90,114,130,137],"carefully":[73],"annotated":[74,97],"data":[75,98],"uncertain":[77],"deterministic":[78],"outputs.":[79],"We":[80,105],"compare":[81],"three":[82,119],"models":[85],"study":[87],"problem":[89],"discriminative":[92],"morphological":[93],"representations":[94],"using":[95],"weakly":[96],"predicting":[100],"also":[106],"estimate":[107],"Bayesian":[108],"uncertainty":[109],"describe":[111],"confidence":[113],"probabilistic":[116],"predictions.":[117],"Amongst":[118],"compared":[120],"models,":[121],"DenseNet":[122],"yielded":[123],"best":[125],"results":[126],"with":[127],"sensitivity":[129],"87.91%\u00b113.22":[131],"at":[132],"false":[134],"negative":[135],"rate":[136],"1.26%\u00b14.18.":[138]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
