{"id":"https://openalex.org/W3026843944","doi":"https://doi.org/10.1109/isbi45749.2020.9098441","title":"Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients","display_name":"Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients","publication_year":2020,"publication_date":"2020-04-01","ids":{"openalex":"https://openalex.org/W3026843944","doi":"https://doi.org/10.1109/isbi45749.2020.9098441","mag":"3026843944"},"language":"en","primary_location":{"id":"doi:10.1109/isbi45749.2020.9098441","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098441","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://researchprofiles.ku.dk/da/publications/fc5f913c-0f77-4b74-9319-39dc2dd9a36a","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034813328","display_name":"Astrid M. E. Engberg","orcid":null},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Astrid M. E. Engberg","raw_affiliation_strings":["Technical University of Denmark"],"affiliations":[{"raw_affiliation_string":"Technical University of Denmark","institution_ids":["https://openalex.org/I96673099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019206497","display_name":"Abdollah Amini","orcid":"https://orcid.org/0000-0002-9408-3200"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Abdullah Amini","raw_affiliation_strings":["Faculty of Health and Medical Sciences, University of Copenhagen"],"affiliations":[{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Copenhagen","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058250943","display_name":"Anne Willerslev","orcid":"https://orcid.org/0000-0002-2337-8968"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Anne Willerslev","raw_affiliation_strings":["Faculty of Health and Medical Sciences, University of Copenhagen"],"affiliations":[{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Copenhagen","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034221126","display_name":"Michael Larsen","orcid":"https://orcid.org/0000-0002-5172-5891"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Michael Larsen","raw_affiliation_strings":["Faculty of Health and Medical Sciences, University of Copenhagen"],"affiliations":[{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Copenhagen","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112172468","display_name":"Birgit Sander","orcid":null},"institutions":[{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Birgit Sander","raw_affiliation_strings":["The Eye Clinic, Rigshospitalet-Glostrup, Denmark"],"affiliations":[{"raw_affiliation_string":"The Eye Clinic, Rigshospitalet-Glostrup, Denmark","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051046432","display_name":"Line Kessel","orcid":"https://orcid.org/0000-0002-9375-1510"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Line Kessel","raw_affiliation_strings":["Faculty of Health and Medical Sciences, University of Copenhagen"],"affiliations":[{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Copenhagen","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031953389","display_name":"Anders Bjorholm Dahl","orcid":"https://orcid.org/0000-0002-0068-8170"},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Anders B. Dahl","raw_affiliation_strings":["Technical University of Denmark"],"affiliations":[{"raw_affiliation_string":"Technical University of Denmark","institution_ids":["https://openalex.org/I96673099"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012770020","display_name":"Vedrana Andersen Dahl","orcid":"https://orcid.org/0000-0001-6734-5570"},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Vedrana A. Dahl","raw_affiliation_strings":["Technical University of Denmark"],"affiliations":[{"raw_affiliation_string":"Technical University of Denmark","institution_ids":["https://openalex.org/I96673099"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5034813328"],"corresponding_institution_ids":["https://openalex.org/I96673099"],"apc_list":null,"apc_paid":null,"fwci":0.3345,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.6248497,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"1987","last_page":"1991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-flow","display_name":"Blood flow","score":0.5875082015991211},{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.5443382859230042},{"id":"https://openalex.org/keywords/angiography","display_name":"Angiography","score":0.5349902510643005},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5261332988739014},{"id":"https://openalex.org/keywords/macular-degeneration","display_name":"Macular degeneration","score":0.4350908100605011},{"id":"https://openalex.org/keywords/optical-coherence-tomography-angiography","display_name":"Optical coherence tomography angiography","score":0.43370458483695984},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3794971704483032},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3451225161552429},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.26290854811668396}],"concepts":[{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5875082015991211},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.5443382859230042},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.5349902510643005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5261332988739014},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.4350908100605011},{"id":"https://openalex.org/C2985858981","wikidata":"https://www.wikidata.org/wiki/Q60760969","display_name":"Optical coherence tomography angiography","level":3,"score":0.43370458483695984},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3794971704483032},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3451225161552429},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.26290854811668396}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi45749.2020.9098441","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098441","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:publications/fc5f913c-0f77-4b74-9319-39dc2dd9a36a","is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/fc5f913c-0f77-4b74-9319-39dc2dd9a36a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Engberg , A M E , Amini , A , Willerslev , A , Larsen , M , Sander , B , Kessel , L , Dahl , A B & Dahl , V A 2020 , Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients . in 2020 IEEE 17th International Symposium on Biomedical Imaging . , 9098441 , IEEE , Proceedings - International Symposium on Biomedical Imaging , vol. 2020-April , pp. 1987-1991 , 17th IEEE International Symposium on Biomedical Imaging, ISBI 2020 , Iowa City , United States , 03/04/2020 . https://doi.org/10.1109/ISBI45749.2020.9098441","raw_type":"contributionToPeriodical"},{"id":"pmh:oai:pure.atira.dk:publications/c9712b46-eefc-47e5-9dc5-8ed87235182f","is_oa":true,"landing_page_url":"https://orbit.dtu.dk/en/publications/c9712b46-eefc-47e5-9dc5-8ed87235182f","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Engberg , A M E , Amini , A , Willerslev , A , Larsen , M , Sander , B , Kessel , L , Dahl , A B &amp; Dahl , V A 2020 , Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients . in Proceedings of 17th IEEE International Symposium on Biomedical Imaging . , 9098441 , IEEE , pp. 1987-1991 , 2020 IEEE International Symposium on Biomedical Imaging , Iowa City , Iowa , United States , 03/04/2020 . https://doi.org/10.1109/ISBI45749.2020.9098441","raw_type":"contributionToPeriodical"}],"best_oa_location":{"id":"pmh:oai:pure.atira.dk:publications/fc5f913c-0f77-4b74-9319-39dc2dd9a36a","is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/fc5f913c-0f77-4b74-9319-39dc2dd9a36a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Engberg , A M E , Amini , A , Willerslev , A , Larsen , M , Sander , B , Kessel , L , Dahl , A B & Dahl , V A 2020 , Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients . in 2020 IEEE 17th International Symposium on Biomedical Imaging . , 9098441 , IEEE , Proceedings - International Symposium on Biomedical Imaging , vol. 2020-April , pp. 1987-1991 , 17th IEEE International Symposium on Biomedical Imaging, ISBI 2020 , Iowa City , United States , 03/04/2020 . https://doi.org/10.1109/ISBI45749.2020.9098441","raw_type":"contributionToPeriodical"},"sustainable_development_goals":[{"score":0.7300000190734863,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W814506198","https://openalex.org/W2066941820","https://openalex.org/W2151103935","https://openalex.org/W2342740558","https://openalex.org/W2408905170","https://openalex.org/W2493158058","https://openalex.org/W2519685943","https://openalex.org/W2526449456","https://openalex.org/W2549537043","https://openalex.org/W2581686684","https://openalex.org/W2743884226","https://openalex.org/W2754791742","https://openalex.org/W2766724135","https://openalex.org/W2767388526","https://openalex.org/W2924535611","https://openalex.org/W2945456648","https://openalex.org/W3000949749","https://openalex.org/W6762685999","https://openalex.org/W6772436658"],"related_works":["https://openalex.org/W3041046439","https://openalex.org/W2994531931","https://openalex.org/W4386789577","https://openalex.org/W4360991425","https://openalex.org/W2049145612","https://openalex.org/W4246192989","https://openalex.org/W2992454348","https://openalex.org/W2321279150","https://openalex.org/W2992711016","https://openalex.org/W1481978003"],"abstract_inverted_index":{"Abnormal":[0],"blood":[1,7,113],"compositions":[2],"can":[3,10,100],"lead":[4],"to":[5,23,60],"abnormal":[6],"flow":[8],"which":[9],"influence":[11],"the":[12,25,63,105],"macular":[13,26],"vasculature.":[14],"Optical":[15],"coherence":[16],"tomography":[17],"angiography":[18],"(OCTA)":[19],"makes":[20],"it":[21],"possible":[22],"study":[24],"vasculature":[27,106],"and":[28,44,49,80,91,94],"potential":[29],"vascular":[30,39,68],"abnormalities":[31],"induced":[32],"by":[33],"hematological":[34],"disorders.":[35],"Here,":[36],"we":[37,70,87,99],"investigate":[38,88],"changes":[40,54,103,111],"in":[41,45,62,104,107,112],"control":[42],"subjects":[43],"hematologic":[46],"patients":[47,90,108],"before":[48],"after":[50],"treatment.":[51],"Since":[52],"these":[53],"are":[55,58],"small,":[56],"they":[57],"difficult":[59],"notice":[61],"OCTA":[64],"images.":[65],"To":[66],"quantify":[67],"changes,":[69],"propose":[71],"a":[72],"method":[73],"for":[74],"combined":[75],"capillary":[76],"registration,":[77],"dictionary-based":[78],"segmentation":[79],"local":[81],"density":[82],"estimation.":[83],"Using":[84],"this":[85],"method,":[86],"three":[89],"five":[92],"controls,":[93],"our":[95],"results":[96],"show":[97],"that":[98],"detect":[101],"small":[102],"with":[109],"large":[110],"composition.":[114]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}
