{"id":"https://openalex.org/W3026560430","doi":"https://doi.org/10.1109/isbi45749.2020.9098398","title":"Circular Anchors for the Detection of Hematopoietic Cells Using Retinanet","display_name":"Circular Anchors for the Detection of Hematopoietic Cells Using Retinanet","publication_year":2020,"publication_date":"2020-04-01","ids":{"openalex":"https://openalex.org/W3026560430","doi":"https://doi.org/10.1109/isbi45749.2020.9098398","mag":"3026560430"},"language":"en","primary_location":{"id":"doi:10.1109/isbi45749.2020.9098398","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098398","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033693993","display_name":"Philipp Gr\u00e4bel","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Philipp Grabel","raw_affiliation_strings":["Institute of Imaging and Computer Vision, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Imaging and Computer Vision, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070656490","display_name":"\u00d6zcan \u00d6zkan","orcid":"https://orcid.org/0000-0002-5216-8361"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ozcan Ozkan","raw_affiliation_strings":["Institute of Imaging and Computer Vision, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Imaging and Computer Vision, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090648381","display_name":"Martina Crysandt","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martina Crysandt","raw_affiliation_strings":["University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052166914","display_name":"Reinhild Herwartz","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Reinhild Herwartz","raw_affiliation_strings":["University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104045857","display_name":"Melanie Baumann","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Melanie Baumann","raw_affiliation_strings":["University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068465621","display_name":"Barbara M. Klinkhammer","orcid":"https://orcid.org/0000-0002-1566-7129"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Barbara M. Klinkhammer","raw_affiliation_strings":["Institute of Pathology, University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Pathology, University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049305761","display_name":"Peter Boor","orcid":"https://orcid.org/0000-0001-9921-4284"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter Boor","raw_affiliation_strings":["Institute of Pathology, University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Pathology, University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024657373","display_name":"Tim H. Br\u00fcmmendorf","orcid":null},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tim H. Brummendorf","raw_affiliation_strings":["University Hospital RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064747056","display_name":"Dorit Merhof","orcid":"https://orcid.org/0000-0002-1672-2185"},"institutions":[{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dorit Merhof","raw_affiliation_strings":["Institute of Imaging and Computer Vision, RWTH Aachen University, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Imaging and Computer Vision, RWTH Aachen University, Germany","institution_ids":["https://openalex.org/I887968799"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5033693993"],"corresponding_institution_ids":["https://openalex.org/I887968799"],"apc_list":null,"apc_paid":null,"fwci":1.1724,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.80905088,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"249","last_page":"253"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.955299973487854,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.659769594669342},{"id":"https://openalex.org/keywords/object-detection","display_name":"Object detection","score":0.5705458521842957},{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.5083391070365906},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"Bone marrow","score":0.4942786693572998},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4355488717556},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.35710588097572327},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.32019615173339844},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13753235340118408},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.09791997075080872}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.659769594669342},{"id":"https://openalex.org/C2776151529","wikidata":"https://www.wikidata.org/wiki/Q3045304","display_name":"Object detection","level":3,"score":0.5705458521842957},{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.5083391070365906},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.4942786693572998},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4355488717556},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.35710588097572327},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.32019615173339844},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13753235340118408},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09791997075080872}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi45749.2020.9098398","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi45749.2020.9098398","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W639708223","https://openalex.org/W1861492603","https://openalex.org/W2037227137","https://openalex.org/W2096688994","https://openalex.org/W2117333179","https://openalex.org/W2565639579","https://openalex.org/W2613718673","https://openalex.org/W2717357949","https://openalex.org/W2889690299","https://openalex.org/W2898745677","https://openalex.org/W2917728795","https://openalex.org/W2963150697","https://openalex.org/W2963351448","https://openalex.org/W2969734936","https://openalex.org/W3037156242","https://openalex.org/W6620707391","https://openalex.org/W6639102338","https://openalex.org/W6755751804"],"related_works":["https://openalex.org/W3166204570","https://openalex.org/W3121246613","https://openalex.org/W2132137594","https://openalex.org/W2093537624","https://openalex.org/W350499458","https://openalex.org/W2062170304","https://openalex.org/W4231562521","https://openalex.org/W4240240174","https://openalex.org/W3128905899","https://openalex.org/W4321784794"],"abstract_inverted_index":{"Analysis":[0],"of":[1,15,105,142],"the":[2,103,115,140],"blood":[3],"cell":[4],"distribution":[5],"in":[6,31,44,54,67,125,131],"bone":[7,132],"marrow":[8,133],"is":[9,25,90],"necessary":[10],"for":[11],"a":[12,58],"detailed":[13],"diagnosis":[14],"many":[16],"hematopoietic":[17,129],"diseases,":[18],"such":[19],"as":[20],"leukemia.":[21],"While":[22],"this":[23,68,89],"task":[24],"performed":[26],"manually":[27],"on":[28,128],"microscope":[29],"images":[30,134],"clinical":[32],"routine,":[33],"automating":[34],"it":[35],"could":[36],"improve":[37],"reliability":[38],"and":[39,81,146],"objectivity.":[40],"Cell":[41],"detection":[42,65,148],"tasks":[43],"medical":[45],"imaging":[46],"have":[47],"successfully":[48],"been":[49],"solved":[50],"using":[51],"deep":[52],"learning,":[53],"particular":[55],"with":[56,96,121],"RetinaNet,":[57],"powerful":[59],"network":[60],"architecture":[61],"that":[62,119,123,136],"yields":[63],"good":[64],"results":[66],"scenario.":[69],"It":[70],"utilizes":[71],"axis-parallel,":[72],"rectangular":[73],"bounding":[74],"boxes":[75],"to":[76,114],"describe":[77],"an":[78,112],"object's":[79],"position":[80],"size.":[82,126],"However,":[83],"since":[84],"cells":[85,106,130],"are":[86],"mostly":[87],"circular,":[88],"suboptimal.":[91],"We":[92,109],"replace":[93],"RetinaNet's":[94],"anchors":[95],"more":[97,107],"suitable":[98],"Circular":[99],"Anchors,":[100],"which":[101],"cover":[102],"shape":[104],"precisely.":[108],"further":[110],"introduce":[111],"extension":[113],"Non-maximum":[116],"Suppression":[117],"algorithm":[118],"copes":[120],"predictions":[122,145],"differ":[124],"Experiments":[127],"show":[135],"these":[137],"methods":[138],"reduce":[139],"number":[141],"false":[143],"positive":[144],"increase":[147],"accuracy.":[149]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
