{"id":"https://openalex.org/W2944550885","doi":"https://doi.org/10.1109/isbi.2019.8759322","title":"Ink Removal from Histopathology Whole Slide Images by Combining Classification, Detection and Image Generation Models","display_name":"Ink Removal from Histopathology Whole Slide Images by Combining Classification, Detection and Image Generation Models","publication_year":2019,"publication_date":"2019-04-01","ids":{"openalex":"https://openalex.org/W2944550885","doi":"https://doi.org/10.1109/isbi.2019.8759322","mag":"2944550885"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2019.8759322","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2019.8759322","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080765299","display_name":"Sharib Ali","orcid":"https://orcid.org/0000-0003-1313-3542"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210160384","display_name":"Institute of Biomedical Science","ror":"https://ror.org/05t77d857","country_code":"GB","type":"other","lineage":["https://openalex.org/I4210160384"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Sharib Ali","raw_affiliation_strings":["Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford","institution_ids":["https://openalex.org/I4210160384","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056257417","display_name":"Nasullah Khalid Alham","orcid":"https://orcid.org/0000-0003-1479-3251"},"institutions":[{"id":"https://openalex.org/I4210160384","display_name":"Institute of Biomedical Science","ror":"https://ror.org/05t77d857","country_code":"GB","type":"other","lineage":["https://openalex.org/I4210160384"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nasullah Khalid Alham","raw_affiliation_strings":["Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford","institution_ids":["https://openalex.org/I4210160384","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090096123","display_name":"Clare Verrill","orcid":"https://orcid.org/0000-0002-4905-8233"},"institutions":[{"id":"https://openalex.org/I4210146357","display_name":"Oxford BioMedica (United Kingdom)","ror":"https://ror.org/03dp0vf82","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210146357"]},{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Clare Verrill","raw_affiliation_strings":["Nuffield Department of Surgical Sciences and Oxford NIHR Biomedical Research Centre (BRC), University of Oxford, John Radcliffe Hospital, Oxford"],"affiliations":[{"raw_affiliation_string":"Nuffield Department of Surgical Sciences and Oxford NIHR Biomedical Research Centre (BRC), University of Oxford, John Radcliffe Hospital, Oxford","institution_ids":["https://openalex.org/I4210146357","https://openalex.org/I40120149","https://openalex.org/I2802742124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027416348","display_name":"Jens Rittscher","orcid":"https://orcid.org/0000-0002-8528-8298"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210160384","display_name":"Institute of Biomedical Science","ror":"https://ror.org/05t77d857","country_code":"GB","type":"other","lineage":["https://openalex.org/I4210160384"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jens Rittscher","raw_affiliation_strings":["Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford","institution_ids":["https://openalex.org/I4210160384","https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5080765299"],"corresponding_institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210160384"],"apc_list":null,"apc_paid":null,"fwci":1.2602,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.84868468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"928","last_page":"932"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10775","display_name":"Generative Adversarial Networks and Image Synthesis","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11105","display_name":"Advanced Image Processing Techniques","score":0.9722999930381775,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7472447156906128},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7330365777015686},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.6265692114830017},{"id":"https://openalex.org/keywords/convolution","display_name":"Convolution (computer science)","score":0.5853777527809143},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.5812503695487976},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5326884388923645},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.473865270614624},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.4484173059463501},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.4254266619682312},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.40572673082351685}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7472447156906128},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7330365777015686},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6265692114830017},{"id":"https://openalex.org/C45347329","wikidata":"https://www.wikidata.org/wiki/Q5166604","display_name":"Convolution (computer science)","level":3,"score":0.5853777527809143},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.5812503695487976},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5326884388923645},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.473865270614624},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.4484173059463501},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4254266619682312},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.40572673082351685},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2019.8759322","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2019.8759322","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4699999988079071,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G1277543710","display_name":null,"funder_award_id":"EP/M013774/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1670560428","https://openalex.org/W2095114940","https://openalex.org/W2099471712","https://openalex.org/W2132162500","https://openalex.org/W2795574863","https://openalex.org/W2796347433","https://openalex.org/W2962793481","https://openalex.org/W2962793691","https://openalex.org/W4293584584","https://openalex.org/W4320013936","https://openalex.org/W6750227808"],"related_works":["https://openalex.org/W4293226380","https://openalex.org/W3135697610","https://openalex.org/W2085033728","https://openalex.org/W4285411112","https://openalex.org/W2964954556","https://openalex.org/W2044092692","https://openalex.org/W2614621130","https://openalex.org/W2547665164","https://openalex.org/W3103111272","https://openalex.org/W4289655544"],"abstract_inverted_index":{"Histopathology":[0],"slides":[1],"are":[2,27],"routinely":[3],"marked":[4,28],"by":[5],"pathologists":[6],"using":[7,97],"permanent":[8],"ink":[9,70],"markers":[10],"that":[11,101,158],"should":[12],"not":[13],"be":[14],"removed":[15],"as":[16,82],"they":[17,83],"form":[18],"part":[19],"of":[20,33,68,124,143],"the":[21,31,56],"medical":[22],"record.":[23],"Often":[24],"tumour":[25],"regions":[26,86],"up":[29],"for":[30,51,121,141],"purpose":[32],"highlighting":[34],"features":[35],"or":[36],"other":[37],"downstream":[38],"processing":[39],"such":[40],"an":[41,89,94],"gene":[42],"sequencing.":[43],"Once":[44],"digitised":[45],"there":[46],"is":[47,77],"no":[48],"established":[49],"method":[50],"removing":[52],"this":[53],"information":[54,108],"from":[55,71],"whole":[57,74,154,165],"slide":[58,75,155,166],"images":[59,76,105,156],"limiting":[60],"its":[61],"usability":[62],"in":[63,88,103],"research":[64],"and":[65,79,87,109,132,148],"study.":[66],"Removal":[67],"marker":[69],"these":[72],"high-resolution":[73],"non-trivial":[78],"complex":[80],"problem":[81],"contaminate":[84],"different":[85,153],"inconsistent":[90],"manner.":[91],"We":[92],"propose":[93],"efficient":[95],"pipeline":[96,113],"convolution":[98,118],"neural":[99,119],"networks":[100],"results":[102,150],"ink-free":[104,164],"without":[106],"compromising":[107],"image":[110,126],"resolution.":[111],"Our":[112],"includes":[114],"a":[115,128,133],"sequential":[116],"classical":[117],"network":[120],"accurate":[122],"classification":[123],"contaminated":[125],"tiles,":[127],"fast":[129],"region":[130],"detector":[131],"domain":[134],"adaptive":[135],"cycle":[136],"consistent":[137],"adversarial":[138],"generative":[139],"model":[140],"restoration":[142],"foreground":[144],"pixels.":[145],"Both":[146],"quantitative":[147],"qualitative":[149],"on":[151],"four":[152],"show":[157],"our":[159],"approach":[160],"yields":[161],"visually":[162],"coherent":[163],"images.":[167]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}