{"id":"https://openalex.org/W2911412243","doi":"https://doi.org/10.1109/isbi.2019.8759103","title":"Improving 3D MA-TIRF Reconstruction with Deconvolution and Background Estimation","display_name":"Improving 3D MA-TIRF Reconstruction with Deconvolution and Background Estimation","publication_year":2019,"publication_date":"2019-04-01","ids":{"openalex":"https://openalex.org/W2911412243","doi":"https://doi.org/10.1109/isbi.2019.8759103","mag":"2911412243"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2019.8759103","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2019.8759103","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://infoscience.epfl.ch/record/267672","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082606466","display_name":"Emmanuel Soubies","orcid":"https://orcid.org/0000-0003-0571-6983"},"institutions":[{"id":"https://openalex.org/I4210133377","display_name":"Centre d'Imagerie BioMedicale","ror":"https://ror.org/03fw2bn12","country_code":"CH","type":"facility","lineage":["https://openalex.org/I4210133377"]},{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Emmanuel Soubies","raw_affiliation_strings":["Biomedical Imaging Group, EPFL, Lausanne, Switzerland","Biomedical Imaging Group [Lausanne] (EPFL/STI/IMT/LIB BM 4.134 (B\u00e2timent BM) Station 17 CH-1015 Lausanne VD Switzerlan - Switzerland)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Imaging Group, EPFL, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210133377","https://openalex.org/I5124864"]},{"raw_affiliation_string":"Biomedical Imaging Group [Lausanne] (EPFL/STI/IMT/LIB BM 4.134 (B\u00e2timent BM) Station 17 CH-1015 Lausanne VD Switzerlan - Switzerland)","institution_ids":["https://openalex.org/I5124864","https://openalex.org/I4210133377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088603553","display_name":"Laure Blanc-F\u00e9raud","orcid":"https://orcid.org/0000-0002-9693-6924"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I1326498283","display_name":"Institut national de recherche en sciences et technologies du num\u00e9rique","ror":"https://ror.org/02kvxyf05","country_code":"FR","type":"government","lineage":["https://openalex.org/I1326498283"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laure Blanc-Feraud","raw_affiliation_strings":["Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inria, I3S, France","MORPHEME - Morphologie et Images (Laboratoire I3S - Algorithmes - Sophia Antipolis\r\nroute des lucioles\r\n06902 Sophia Antipolis - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inria, I3S, France","institution_ids":["https://openalex.org/I1326498283","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"MORPHEME - Morphologie et Images (Laboratoire I3S - Algorithmes - Sophia Antipolis\r\nroute des lucioles\r\n06902 Sophia Antipolis - France)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038534132","display_name":"S\u00e9bastien Schaub","orcid":"https://orcid.org/0000-0002-9624-3271"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I4210117840","display_name":"Institut de Biologie Valrose","ror":"https://ror.org/03bnma344","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210117840"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sebastien Schaub","raw_affiliation_strings":["Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inserm, iBV, France","IBV - Institut de Biologie Valrose (Facult\u00e9 des Sciences, parc Valrose 06108 Nice cedex 2 - France)","MORPHEME - Morphologie et Images (Laboratoire I3S - Algorithmes - Sophia Antipolis\r\nroute des lucioles\r\n06902 Sophia Antipolis - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inserm, iBV, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I201841394","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"IBV - Institut de Biologie Valrose (Facult\u00e9 des Sciences, parc Valrose 06108 Nice cedex 2 - France)","institution_ids":["https://openalex.org/I4210117840"]},{"raw_affiliation_string":"MORPHEME - Morphologie et Images (Laboratoire I3S - Algorithmes - Sophia Antipolis\r\nroute des lucioles\r\n06902 Sophia Antipolis - France)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082652915","display_name":"Ellen Van Obberghen\u2010Schilling","orcid":"https://orcid.org/0000-0003-2961-0059"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]},{"id":"https://openalex.org/I4210117840","display_name":"Institut de Biologie Valrose","ror":"https://ror.org/03bnma344","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I201841394","https://openalex.org/I4210096427","https://openalex.org/I4210117840"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ellen Van Obberghen-Schilling","raw_affiliation_strings":["Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inserm, iBV, France","IBV - Institut de Biologie Valrose (Facult\u00e9 des Sciences, parc Valrose 06108 Nice cedex 2 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 C\u00f4te d\u2019Azur, CNRS, Inserm, iBV, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I201841394","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"IBV - Institut de Biologie Valrose (Facult\u00e9 des Sciences, parc Valrose 06108 Nice cedex 2 - France)","institution_ids":["https://openalex.org/I4210117840"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2642,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74382398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"111","issue":null,"first_page":"316","last_page":"320"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10638","display_name":"Optical measurement and interference techniques","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-internal-reflection-fluorescence-microscope","display_name":"Total internal reflection fluorescence microscope","score":0.8735041618347168},{"id":"https://openalex.org/keywords/deconvolution","display_name":"Deconvolution","score":0.8391771912574768},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.6253379583358765},{"id":"https://openalex.org/keywords/reflection","display_name":"Reflection (computer programming)","score":0.6010457873344421},{"id":"https://openalex.org/keywords/autofluorescence","display_name":"Autofluorescence","score":0.5492281913757324},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.5358335375785828},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.47476840019226074},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4436093866825104},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.4433671832084656},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.41327065229415894},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4029022753238678},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.32150471210479736},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2941536009311676},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.2606143355369568}],"concepts":[{"id":"https://openalex.org/C121381206","wikidata":"https://www.wikidata.org/wiki/Q902514","display_name":"Total internal reflection fluorescence microscope","level":3,"score":0.8735041618347168},{"id":"https://openalex.org/C174576160","wikidata":"https://www.wikidata.org/wiki/Q1183700","display_name":"Deconvolution","level":2,"score":0.8391771912574768},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.6253379583358765},{"id":"https://openalex.org/C65682993","wikidata":"https://www.wikidata.org/wiki/Q1056451","display_name":"Reflection (computer programming)","level":2,"score":0.6010457873344421},{"id":"https://openalex.org/C179687394","wikidata":"https://www.wikidata.org/wiki/Q4826281","display_name":"Autofluorescence","level":3,"score":0.5492281913757324},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.5358335375785828},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.47476840019226074},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4436093866825104},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.4433671832084656},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41327065229415894},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4029022753238678},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.32150471210479736},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2941536009311676},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.2606143355369568},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2019.8759103","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2019.8759103","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)","raw_type":"proceedings-article"},{"id":"pmh:oai:HAL:hal-02017862v1","is_oa":false,"landing_page_url":"https://inria.hal.science/hal-02017862","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE International Symposium on Biomedical Imaging, Apr 2019, Venise, Italy. ⟨10.1109/ISBI.2019.8759103⟩","raw_type":"Conference papers"},{"id":"pmh:oai:infoscience.epfl.ch:267672","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/267672","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference proceedings"}],"best_oa_location":{"id":"pmh:oai:infoscience.epfl.ch:267672","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/267672","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference proceedings"},"sustainable_development_goals":[{"display_name":"Sustainable cities and communities","score":0.5299999713897705,"id":"https://metadata.un.org/sdg/11"}],"awards":[{"id":"https://openalex.org/G2113015678","display_name":"3IA C\u00f4te d'Azur","funder_award_id":"ANR-19-P3IA-0002","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G4347508432","display_name":"HOW PERICELLULAR MATRIX ORCHESTRATES THE ANGIOGENIC-TO-FIBROTIC TRANSITION","funder_award_id":"ANR-16-CE93-0005","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8533281491","display_name":"R\u00e9seau d'Innovation sur les Voies de Signalisation en Sciences de la Vie","funder_award_id":"ANR-11-LABX-0028","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1482162053","https://openalex.org/W1556700452","https://openalex.org/W1946620893","https://openalex.org/W1965598222","https://openalex.org/W1984866494","https://openalex.org/W2006493427","https://openalex.org/W2016235229","https://openalex.org/W2017269957","https://openalex.org/W2028406120","https://openalex.org/W2051542254","https://openalex.org/W2055926624","https://openalex.org/W2066597100","https://openalex.org/W2087685763","https://openalex.org/W2103559027","https://openalex.org/W2104624493","https://openalex.org/W2109673107","https://openalex.org/W2168665798","https://openalex.org/W2189364169","https://openalex.org/W2343038172","https://openalex.org/W2402771360","https://openalex.org/W2429729482","https://openalex.org/W2523119813","https://openalex.org/W2594812954","https://openalex.org/W2722359275","https://openalex.org/W2792727068","https://openalex.org/W2811277086","https://openalex.org/W2912767819","https://openalex.org/W4290646776","https://openalex.org/W6740075939"],"related_works":["https://openalex.org/W3035217167","https://openalex.org/W2131421679","https://openalex.org/W2751042822","https://openalex.org/W2255376542","https://openalex.org/W2967085485","https://openalex.org/W2903601283","https://openalex.org/W4300430230","https://openalex.org/W2967568476","https://openalex.org/W2141744736","https://openalex.org/W1978169319"],"abstract_inverted_index":{"Total":[0],"internal":[1],"reflection":[2],"fluorescence":[3],"microscopy":[4,89],"(TIRF)":[5],"produces":[6],"2D":[7,34],"images":[8,35],"of":[9,33,48,73,96,123,131,145,154,167],"the":[10,21,26,45,49,71,74,94,97,102,120,132,146,152,156,160,165,168],"fluorescent":[11],"activity":[12],"integrated":[13],"over":[14],"a":[15,31,128],"very":[16],"thin":[17],"layer":[18],"adjacent":[19],"to":[20,43,54,64,137],"glass":[22],"coverslip.":[23],"By":[24],"varying":[25],"illumination":[27],"angle":[28],"(multi-angle":[29],"TIRF),":[30],"stack":[32],"is":[36,41,62],"acquired":[37],"from":[38],"which":[39,90,135,163],"it":[40],"possible":[42],"estimate":[44],"axial":[46],"position":[47],"observed":[50],"biological":[51,68],"structures.":[52],"Due":[53],"its":[55],"unique":[56],"optical":[57],"sectioning":[58],"capability,":[59],"this":[60,78],"technique":[61],"ideal":[63],"observe":[65],"and":[66,101,113],"study":[67],"processes":[69],"at":[70,142],"vicinity":[72],"cell":[75],"membrane.":[76],"In":[77],"paper,":[79],"we":[80],"propose":[81],"an":[82],"efficient":[83],"reconstruction":[84,161],"algorithm":[85],"for":[86,92],"multi-angle":[87],"TIRF":[88],"accounts":[91],"both":[93],"PSF":[95],"acquisition":[98],"system":[99],"(diffraction)":[100],"background":[103,114,157],"signal":[104,158],"(e.g.,":[105],"autofluorescence).":[106],"It":[107],"jointly":[108],"performs":[109],"volume":[110],"reconstruction,":[111],"deconvolution,":[112],"estimation.":[115],"This":[116],"algorithm,":[117],"based":[118],"on":[119,127],"simultaneous-direction":[121],"method":[122],"multipliers":[124],"(SDMM),":[125],"relies":[126],"suitable":[129],"splitting":[130],"optimization":[133],"problem":[134],"allows":[136],"obtain":[138],"closed":[139],"form":[140],"solutions":[141],"each":[143],"step":[144],"algorithm.":[147],"Finally,":[148],"numerical":[149],"experiments":[150],"reveal":[151],"importance":[153],"considering":[155],"into":[159],"process,":[162],"reinforces":[164],"relevance":[166],"proposed":[169],"approach.":[170]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-06-22T08:00:12.763002","created_date":"2025-10-10T00:00:00"}